Divergent activities of osteogenic BMP2, and tenogenic BMP12 and BMP13 independent of receptor binding affinities

Growth Factors

Volumn 29, Issue 4, 2011, Pages 128-139

  Berasi, Stephen P ^a   Varadarajan, Usha ^a   Archambault, Joanne ^a   Cain, Michael ^a   Souza, Tatyana A ^a   Abouzeid, Abe ^a   Li, Jian ^a   Brown, Christopher T ^a   Dorner, Andrew J ^a   J Seeherman, Howard ^a   Jelinsky, Scott A ^a  

^a PFIZER INC   (United States)

Author keywords

Bone morphogenetic proteins; Tendon markers; Thrombospondin 4

Indexed keywords

ACTIVIN RECEPTOR 2; ACTIVIN RECEPTOR 2A; ACTIVIN RECEPTOR 2B; BIOLOGICAL MARKER; BONE MORPHOGENETIC PROTEIN RECEPTOR 1A; BONE MORPHOGENETIC PROTEIN RECEPTOR 1B; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; MESSENGER RNA; OSTEOCALCIN; RECOMBINANT BONE MORPHOGENETIC PROTEIN 12; RECOMBINANT BONE MORPHOGENETIC PROTEIN 13; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; RECOMBINANT GROWTH FACTOR; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; THBS4 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; GENE INDUCTION; IN VIVO STUDY; INTRACELLULAR SIGNALING; MALE; MUSCLE DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR AFFINITY; TENDON DEVELOPMENT;

ACTIVIN RECEPTORS; ANIMALS; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE I; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II; BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; CELL LINE; GROWTH DIFFERENTIATION FACTOR 6; GROWTH DIFFERENTIATION FACTORS; HUMANS; MICE; MICE, INBRED C3H; OSTEOCALCIN; OSTEOGENESIS; POLYMERASE CHAIN REACTION; PROTEIN BINDING; RECOMBINANT PROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; SMAD PROTEINS; TENDONS; THROMBOSPONDINS;

EID: 79960357508     PISSN: 08977194     EISSN: 10292292     Source Type: Journal    
DOI: 10.3109/08977194.2011.593178     Document Type: Article

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