Bacterial translocation is reduced by a specific nutritional combination in mice with chemotherapy-induced neutropenia

Journal of Nutrition

Volumn 141, Issue 7, 2011, Pages 1292-1298

  Faber, Joyce ^a,b   van Limpt, Kees ^a   Kegler, Diane ^a   Luiking, Yvette ^a,c   Garssen, Johan ^a,b   van Helvoort, Ardy ^a   Vos, Arjan Paul ^a,b   Knol, Jan ^a  

^a DANONE RESEARCH   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHOSPHAMIDE; CYTOKINE; FISH OIL; LEUCINE; OLIGOSACCHARIDE; PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL COUNT; BACTERIAL TRANSLOCATION; CONTROLLED STUDY; DIET SUPPLEMENTATION; FECES; FEMALE; LIVER; LUNG; MOUSE; NEUTROPENIA; NONHUMAN; PH; PROTEIN BLOOD LEVEL; PROTEIN DIET; PSEUDOMONAS AERUGINOSA;

ANIMALS; ANTINEOPLASTIC AGENTS; BACTERIAL TRANSLOCATION; CYCLOPHOSPHAMIDE; CYTOKINES; DIETARY PROTEINS; DIETARY SUPPLEMENTS; DINOPROSTONE; DISEASE MODELS, ANIMAL; FECES; FEMALE; FISH OILS; HYDROGEN-ION CONCENTRATION; LEUCINE; MICE; MICE, INBRED C3H; NEUTROPENIA; OLIGOSACCHARIDES; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS;

BACTERIA (MICROORGANISMS); MUS; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS AERUGINOSA PAO1;

EID: 79960300039     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.110.136986     Document Type: Article

References (46)

1. Hadden JW. Immunodeficiency and cancer: prospects for correction. Int Immunopharmacol. 2003;3:1061-71.
2. Evans C, Dalgleish AG, Kumar D. Review article: immune suppression and colorectal cancer. Aliment Pharmacol Ther. 2006;24:1163-77.
3. Ben-Baruch A. Inflammation-associated immune suppression in cancer: the roles played by cytokines, chemokines and additional mediators. Semin Cancer Biol. 2006;16:38-52.
4. Allavena P, Sica A, Garlanda C, Mantovani A. The yin-yang of tumorassociated macrophages in neoplastic progression and immune surveillance. Immunol Rev. 2008;222:155-61.
5. Dolcetti L, Marigo I, Mantelli B, Peranzoni E, Zanovello P, Bronte V. Myeloid-derived suppressor cell role in tumor-related inflammation. Cancer Lett. 2008;267:216-25.
6. Allavena P, Garlanda C, Borrello MG, Sica A, Mantovani A. Pathways connecting inflammation and cancer. Curr Opin Genet Dev. 2008;18: 3-10.
7. Mantovani A. Cancer: inflaming metastasis. Nature. 2009;457:36-7.
8. Van Cutsem E, Arends J. The causes and consequences of cancerassociated malnutrition. Eur J Oncol Nurs. 2005;9 Suppl 2:S51-63.
9. Kuderer NM, Dale DC, Crawford J, Cosler LE, Lyman GH. Mortality, morbidity, and cost associated with febrile neutropenia in adult cancer patients. Cancer. 2006;106:2258-66.
10. Whimbey E, Englund JA, Couch RB. Community respiratory virus infections in immunocompromised patients with cancer. Am J Med. 1997;102:10-8, discussion 25-6.
11. Senesse P, Assenat E, Schneider S, Chargari C, Magne N, Azria D, Hebuterne X. Nutritional support during oncologic treatment of patients with gastrointestinal cancer: who could benefit? Cancer Treat Rev. 2008; 34:568-75.
12. Stringer AM, Gibson RJ, Bowen JM, Keefe DM. Chemotherapy-induced modifications to gastrointestinal microflora: evidence and implications of change. Curr Drug Metab. 2009;10:79-83.
13. Keefe DM, Cummins AG, Dale BM, Kotasek D, Robb TA, Sage RE. Effect of high-dose chemotherapy on intestinal permeability in humans. Clin Sci (Lond). 1997;92:385-9.
14. Gibson RJ, Stringer AM. Chemotherapy-induced diarrhoea. Curr Opin Support Palliat Care. 2009;3:31-5.
15. Wessner B, Strasser EM, Koitz N, Schmuckenschlager C, Unger-Manhart N, Roth E. Green tea polyphenol administration partly ameliorates chemotherapy-induced side effects in the small intestine of mice. J Nutr. 2007;137:634-40.
16. van Bokhorst-de van der SchuerenMA. Nutritional support strategies for malnourished cancer patients. Eur J Oncol Nurs. 2005;9 Suppl 2:S74-83.
17. del Giglio A, Eniu A, Ganea-Motan D, Topuzov E, Lubenau H. XM02 is superior to placebo and equivalent to Neupogen in reducing the duration of severe neutropenia and the incidence of febrile neutropenia in cycle 1 in breast cancer patients receiving docetaxel/doxorubicin chemotherapy. BMC Cancer. 2008;8:332.
18. Rolston KVI. Bacterial infection in neutropenic cancer patients: an overview. Iranian Journal of Clinical Infectious Diseases. 2009;4:8.
19. Klastersky J, Ameye L, Maertens J, Georgala A, Muanza F, Aoun M, Ferrant A, Rapoport B, Rolston K, et al. Bacteraemia in febrile neutropenic cancer patients. Int J Antimicrob Agents. 2007;30 Suppl 1:S51-9.
20. Koh AY, Priebe GP, Pier GB. Virulence of Pseudomonas aeruginosa in a murine model of gastrointestinal colonization and dissemination in neutropenia. Infect Immun. 2005;73:2262-72.
21. Mutlu GM, Wunderink RG. Severe pseudomonal infections. Curr Opin Crit Care. 2006;12:458-63.
22. Tetaert D, Pierre M, Demeyer D, Husson MO, Beghin L, Galabert C, Gottrand F, Beermann C, Guery B, et al. Dietary n-3 fatty acids have suppressive effects on mucin upregulation in mice infected with Pseudomonas aeruginosa. Respir Res. 2007;8:39.
23. Faber J, Vos P, Kegler D, van Norren K, Argiles JM, Laviano A, Garssen J, van Helvoort A. Beneficial immune modulatory effects of a specific nutritional combination in a murine model for cancer cachexia. Br J Cancer. 2008;99:2029-36.
24. van Norren K, Kegler D, Argiles JM, Luiking Y, Gorselink M, Laviano A, Arts K, Faber J, Jansen H, et al. Dietary supplementation with a specific combination of high protein, leucine, and fish oil improves muscle function and daily activity in tumour-bearing cachectic mice. Br J Cancer. 2009;100:713-22.
25. Matsumoto T, Tateda K, Miyazaki S, Furuya N, Ohno A, Ishii Y, Hirakata Y, Yamaguchi K. Adverse effects of tumour necrosis factor in cyclophosphamide-treated mice subjected to gut-derived Pseudomonas aeruginosa sepsis. Cytokine. 1997;9:763-9.
26. Urano T, Maejima K. Provocation of pseudomoniasis with cyclophosphamide in mice. Lab Anim. 1978;12:159-61.
27. Van Leeuwen PA, Boermeester MA, Houdijk AP, Ferwerda CC, Cuesta MA, Meyer S, Wesdorp RI. Clinical significance of translocation. Gut. 1994;35:S28-34.
28. MacFie J, O'Boyle C, Mitchell CJ, Buckley PM, Johnstone D, Sudworth P. Gut origin of sepsis: a prospective study investigating associations between bacterial translocation, gastric microflora, and septic morbidity. Gut. 1999;45:223-8.
29. Reeves PG. Components of the AIN-93 diets as improvements in the AIN-76A diet. J Nutr. 1997;127:S838-41.
30. Steele TA. Chemotherapy-induced immunosuppression and reconstitution of immune function. Leuk Res. 2002;26:411-4.
31. Vos AP, M'Rabet L, Stahl B, Boehm G, Garssen J. Immune-modulatory effects and potential working mechanisms of orally applied nondigestible carbohydrates. Crit Rev Immunol. 2007;27:97-140.
32. Macfarlane GT, Steed H, Macfarlane S. Bacterial metabolism and healthrelated effects of galacto-oligosaccharides and other prebiotics. J Appl Microbiol. 2008;104:305-44.
33. Worthley DL, Le Leu RK, Whitehall VL, Conlon M, Christophersen C, Belobrajdic D, Mallitt KA, Hu Y, Irahara N, et al. A human, doubleblind, placebo-controlled, crossover trial of prebiotic, probiotic, and synbiotic supplementation: effects on luminal, inflammatory, epigenetic, and epithelial biomarkers of colorectal cancer. Am J Clin Nutr. 2009; 90:578-86.
34. Boehm G, Moro G. Structural and functional aspects of prebiotics used in infant nutrition. J Nutr. 2008;138:1818S-28S.
35. Andremont A, Marang B, Tancrede C, Baume D, Hill C. Antibiotic treatment and intestinal colonization by Pseudomonas aeruginosa in cancer patients. Antimicrob Agents Chemother. 1989;33:1400-2.
36. Alexander JW. Bacterial translocation during enteral and parenteral nutrition. Proc Nutr Soc. 1998;57:389-93.
37. Pscheidl E, Schywalsky M, Tschaikowsky K, Boke-Prols T. Fish oilsupplemented parenteral diets normalize splanchnic blood flow and improve killing of translocated bacteria in a low-dose endotoxin rat model. Crit Care Med. 2000;28:1489-96.
38. Calder PC. Use of fish oil in parenteral nutrition: rationale and reality. Proc Nutr Soc. 2006;65:264-77.
39. Bjornsson S, Hardardottir I, Gunnarsson E, Haraldsson A. Dietary fish oil supplementation increases survival in mice following Klebsiella pneumoniae infection. Scand J Infect Dis. 1997;29:491-3.
40. Calder PC. n-3 Polyunsaturated fatty acids, inflammation, and inflammatory diseases. Am J Clin Nutr. 2006;83:S1505-19.
41. Wu D, Meydani SN. n-3 Polyunsaturated fatty acids and immune function. Proc Nutr Soc. 1998;57:503-9.
42. Tiesset H, Pierre M, Desseyn JL, Guery B, Beermann C, Galabert C, Gottrand F, Husson MO. Dietary (n-3) polyunsaturated fatty acids affect the kinetics of pro- and antiinflammatory responses in mice with Pseudomonas aeruginosa lung infection. J Nutr. 2009;139: 82-9.
43. Reeves PG, Nielsen FH, Fahey GC Jr. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr. 1993;123:1939-51.
44. Xue H, Sawyer MB, Wischmeyer PE, Baracos VE. Nutrition modulation of gastrointestinal toxicity related to cancer chemotherapy: from preclinical findings to clinical strategy. JPEN J Parenter Enteral Nutr. 2011; 35:74-90.
45. Robinson LE, Clandinin MT, Field CJ. The role of dietary long-chain n-3 fatty acids in anti-cancer immune defense and R3230AC mammary tumor growth in rats: influence of diet fat composition. Breast Cancer Res Treat. 2002;73:145-60.
46. Baracos VE, Mazurak VC, Ma DW. n-3 Polyunsaturated fatty acids throughout the cancer trajectory: influence on disease incidence, progression, response to therapy and cancer-associated cachexia. Nutr Res Rev. 2004;17:177-92.