메뉴 건너뛰기




Volumn 2, Issue 5, 2011, Pages 995-1001

Overexpression of Hedgehog signaling molecules and its involvement in triple-negative breast cancer

Author keywords

Cancer stem cell; Glioma associated oncogene homoglog 1; Patched 1; Smoothened; Sonic Hedgehog; Triple negative breast cancer

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR; PROTEIN PATCHED 1; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1;

EID: 79960287553     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2011.357     Document Type: Article
Times cited : (68)

References (33)
  • 1
    • 67649225452 scopus 로고    scopus 로고
    • Triple-negative breast cancers express receptors for growth hormone-releasing hormone (GHRH) and respond to GHRH antagonists with growth inhibition
    • Köster F, Engel JB, Schally AV, et al: Triple-negative breast cancers express receptors for growth hormone-releasing hormone (GHRH) and respond to GHRH antagonists with growth inhibition. Breast Cancer Res Treat 116: 273-279, 2009.
    • (2009) Breast Cancer Res Treat , vol.116 , pp. 273-279
    • Köster, F.1    Engel, J.B.2    Schally, A.V.3
  • 2
    • 33847063053 scopus 로고    scopus 로고
    • The triple negative paradox: Primary tumor chemosensitivity of breast cancer subtypes
    • Carey LA, Dees EC, Sawyer L, et al: The triple negative paradox: primary tumor chemosensitivity of breast cancer subtypes. Clin Cancer Res 13: 2329-2334, 2007.
    • (2007) Clin Cancer Res , vol.13 , pp. 2329-2334
    • Carey, L.A.1    Dees, E.C.2    Sawyer, L.3
  • 3
    • 60849097255 scopus 로고    scopus 로고
    • Gene-expression signatures in breast cancer
    • Sotiriou C, Phil D and Pusztaj J: Gene-expression signatures in breast cancer. N Engl J Med 360: 790-800, 2009.
    • (2009) N Engl J Med , vol.360 , pp. 790-800
    • Sotiriou, C.1    Phil, D.2    Pusztaj, J.3
  • 4
    • 41649102048 scopus 로고    scopus 로고
    • Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer
    • Liedtke C, Mazouni C, Hess KR, et al: Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer. J Clin Oncol 26: 1275-1281, 2008.
    • (2008) J Clin Oncol , vol.26 , pp. 1275-1281
    • Liedtke, C.1    Mazouni, C.2    Hess, K.R.3
  • 6
    • 65249104546 scopus 로고    scopus 로고
    • Triple-negative breast cancer: Distinguishing between basal and nonbasal subtypes
    • Rakha EA, Elsheikh SE, Aleskandarany MA, et al: Triple-negative breast cancer: distinguishing between basal and nonbasal subtypes. Clin Cancer Res 15: 2302-2310, 2009.
    • (2009) Clin Cancer Res , vol.15 , pp. 2302-2310
    • Rakha, E.A.1    Elsheikh, S.E.2    Aleskandarany, M.A.3
  • 7
    • 77449111634 scopus 로고    scopus 로고
    • Metaplastic breast carcinoma: Clinicopathologic features and prognostic value of triple negativity
    • Lim KH, Oh DY, Chie EY, et al: Metaplastic breast carcinoma: clinicopathologic features and prognostic value of triple negativity. Jpn J Clin Oncol 40: 112-118, 2010.
    • (2010) Jpn J Clin Oncol , vol.40 , pp. 112-118
    • Lim, K.H.1    Oh, D.Y.2    Chie, E.Y.3
  • 9
    • 55849132481 scopus 로고    scopus 로고
    • Sites of distant relapse and clinical outcomes in patients with metastatic triple-negative breast cancer: High incidence of central nervous system metastases
    • Lin NU, Claus E, Sohl J, Razzak AR, Arnaout A and Winer EP: Sites of distant relapse and clinical outcomes in patients with metastatic triple-negative breast cancer: high incidence of central nervous system metastases. Cancer 113: 2638-2645, 2008.
    • (2008) Cancer , vol.113 , pp. 2638-2645
    • Lin, N.U.1    Claus, E.2    Sohl, J.3    Razzak, A.R.4    Arnaout, A.5    Winer, E.P.6
  • 10
    • 78650911210 scopus 로고    scopus 로고
    • Triple-negative breast cancer
    • Chacón RD and Costanzo MV: Triple-negative breast cancer. Breast Cancer Res 12 (Suppl 2): 3, 2010.
    • (2010) Breast Cancer Res , vol.12 , Issue.SUPPL. 2 , pp. 3
    • Chacón, R.D.1    Costanzo, M.V.2
  • 14
    • 68949147586 scopus 로고    scopus 로고
    • Hedgehog signaling regulates the survival of gastric cancer cells by regulating the expression of Bcl-2
    • Han ME, Lee YS, Baek SY, Kim BS, Kim JB and Oh SO: Hedgehog signaling regulates the survival of gastric cancer cells by regulating the expression of Bcl-2. Int J Mol Sci 10: 3033-3043, 2009.
    • (2009) Int J Mol Sci , vol.10 , pp. 3033-3043
    • Han, M.E.1    Lee, Y.S.2    Baek, S.Y.3    Kim, B.S.4    Kim, J.B.5    Oh, S.O.6
  • 15
    • 74049138338 scopus 로고    scopus 로고
    • The sonic hedgehog signaling pathway is reactivated in human renal cell carcinoma and plays orchestral role in tumor growth
    • Dormoy V, Danilin S, Lindner V, et al: The sonic hedgehog signaling pathway is reactivated in human renal cell carcinoma and plays orchestral role in tumor growth. Mol Cancer 8: 123, 2009.
    • (2009) Mol Cancer , vol.8 , pp. 123
    • Dormoy, V.1    Danilin, S.2    Lindner, V.3
  • 16
    • 60749093903 scopus 로고    scopus 로고
    • Androgenic regulation of hedgehog signaling pathway components in prostate cancer cells
    • Chen M, Tanner M, Levine AC, Levina E, Ohouo P and Buttyan R: Androgenic regulation of hedgehog signaling pathway components in prostate cancer cells. Cell Cycle 8: 149-157, 2009.
    • (2009) Cell Cycle , vol.8 , pp. 149-157
    • Chen, M.1    Tanner, M.2    Levine, A.C.3    Levina, E.4    Ohouo, P.5    Buttyan, R.6
  • 17
    • 18944407603 scopus 로고    scopus 로고
    • Mammary stem cells, self-renewal pathways, and carcinogenesis
    • Liu S, Dontu G and Wicha MS: Mammary stem cells, self-renewal pathways, and carcinogenesis. Breast Cancer Res 7: 86-95, 2005.
    • (2005) Breast Cancer Res , vol.7 , pp. 86-95
    • Liu, S.1    Dontu, G.2    Wicha, M.S.3
  • 18
    • 33745869471 scopus 로고    scopus 로고
    • Role of sonic hedgehog in maintaining a pool of proliferating stem cells in the human fetal epidermis
    • Zhou JX, Jia LW, Liu WM, Miao CL, Liu S, Cao YJ and Duan EK: Role of sonic hedgehog in maintaining a pool of proliferating stem cells in the human fetal epidermis. Hum Reprod 21: 1698-1704, 2006.
    • (2006) Hum Reprod , vol.21 , pp. 1698-1704
    • Zhou, J.X.1    Jia, L.W.2    Liu, W.M.3    Miao, C.L.4    Liu, S.5    Cao, Y.J.6    Duan, E.K.7
  • 20
    • 33745728170 scopus 로고    scopus 로고
    • Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells
    • Liu S, Dontu G, Mantle ID, Patel S, Ahn NS, Jackson KW, Suri P and Wicha MS: Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells. Cancer Res 66: 6063-6071, 2006.
    • (2006) Cancer Res , vol.66 , pp. 6063-6071
    • Liu, S.1    Dontu, G.2    Mantle, I.D.3    Patel, S.4    Ahn, N.S.5    Jackson, K.W.6    Suri, P.7    Wicha, M.S.8
  • 21
    • 32444445937 scopus 로고    scopus 로고
    • Breast cancer staging: Working with the sixth edition of the AJCC Cancer Staging Manual
    • Singletary SE and Connolly JL: Breast cancer staging: working with the sixth edition of the AJCC Cancer Staging Manual. CA Cancer J Clin 56: 37-47, 2006.
    • (2006) CA Cancer J Clin , vol.56 , pp. 37-47
    • Singletary, S.E.1    Connolly, J.L.2
  • 23
    • 70349786795 scopus 로고    scopus 로고
    • Expression of the glioma-associated oncogene homolog (GLI) 1 in human breast cancer is associated with unfavourable overall survival
    • Ten Haaf A, Bektas N, von Serenyi S, Losen I, Arweiler EC, Hartmann A, Knüchel R and Dahl E: Expression of the glioma-associated oncogene homolog (GLI) 1 in human breast cancer is associated with unfavourable overall survival. BMC Cancer 9: 298-309, 2009.
    • (2009) BMC Cancer , vol.9 , pp. 298-309
    • Ten, H.A.1    Bektas, N.2    von Serenyi, S.3    Losen, I.4    Arweiler, E.C.5    Hartmann, A.6    Knüchel, R.7    Dahl, E.8
  • 24
    • 74549200943 scopus 로고    scopus 로고
    • Mechanisms of inactivation of PTCH1 gene in nevoid basal cell carcinoma syndrome: Modifica- tion of the two-hit hypothesis
    • Pan S, Dong Q, Sun LS and Li TJ: Mechanisms of inactivation of PTCH1 gene in nevoid basal cell carcinoma syndrome: modifica- tion of the two-hit hypothesis. Clin Cancer Res 16: 442-450, 2010.
    • (2010) Clin Cancer Res , vol.16 , pp. 442-450
    • Pan, S.1    Dong, Q.2    Sun, L.S.3    Li, T.J.4
  • 25
    • 70350496540 scopus 로고    scopus 로고
    • Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma
    • Yauch RL, Dijkgraaf GJ, Alicke B, et al: Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma. Science 326: 572-574, 2009.
    • (2009) Science , vol.326 , pp. 572-574
    • Yauch, R.L.1    Dijkgraaf, G.J.2    Alicke, B.3
  • 26
    • 52649111039 scopus 로고    scopus 로고
    • Basal cell carcinomas: Attack of the hedgehog
    • Epstein EH: Basal cell carcinomas: attack of the hedgehog. Nat Rev Cancer 8: 743-754, 2008.
    • (2008) Nat Rev Cancer , vol.8 , pp. 743-754
    • Epstein, E.H.1
  • 27
    • 34247192972 scopus 로고    scopus 로고
    • Hedgehog signaling maintains a tumor stem cell compartment in multiple myeloma
    • Peacock CD, Wang Q, Gesell GS, et al: Hedgehog signaling maintains a tumor stem cell compartment in multiple myeloma. Proc Natl Acad Sci USA 104: 4048-4053, 2007.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 4048-4053
    • Peacock, C.D.1    Wang, Q.2    Gesell, G.S.3
  • 28
    • 34247398806 scopus 로고    scopus 로고
    • Constitutive activation of smoothened (SMO) in mammary glands of transgenic mice leads to increased proliferation, altered differentiation and ductal dysplasia
    • Moraes RC, Zhang X, Harrington N, Fung JY, Wu MF, Hilsenbeck SG, Allred DC and Lewis MT: Constitutive activation of smoothened (SMO) in mammary glands of transgenic mice leads to increased proliferation, altered differentiation and ductal dysplasia. Development 134: 1231-1242, 2007.
    • (2007) Development , vol.134 , pp. 1231-1242
    • Moraes, R.C.1    Zhang, X.2    Harrington, N.3    Fung, J.Y.4    Wu, M.F.5    Hilsenbeck, S.G.6    Allred, D.C.7    Lewis, M.T.8
  • 29
    • 66049102512 scopus 로고    scopus 로고
    • Hedgehog signaling is dispensable for adult hematopoietic stem cell function
    • Gao J, Graves S, Koch U, Liu S, et al: Hedgehog signaling is dispensable for adult hematopoietic stem cell function. Cell Stem Cell 4: 548-558, 2009.
    • (2009) Cell Stem Cell , vol.4 , pp. 548-558
    • Gao, J.1    Graves, S.2    Koch, U.3    Liu, S.4
  • 30
    • 64749091867 scopus 로고    scopus 로고
    • Hedgehog signaling is essential for maintenance of cancer stem cells in myeloid leukaemia
    • Zhao C, Chen A, Jamieson CH, et al: Hedgehog signaling is essential for maintenance of cancer stem cells in myeloid leukaemia. Nature 458: 776-779, 2009.
    • (2009) Nature , vol.458 , pp. 776-779
    • Zhao, C.1    Chen, A.2    Jamieson, C.H.3
  • 32
    • 72449206262 scopus 로고    scopus 로고
    • Expression of Gli1 correlates with the transition of breast cancer cells to estrogen-independent growth
    • Zhao J, Chen G, Cao D, Li Y, Diao F, Cai H, Jin Y and Lu J: Expression of Gli1 correlates with the transition of breast cancer cells to estrogen-independent growth. Breast Cancer Res Treat 119: 39-51, 2010.
    • (2010) Breast Cancer Res Treat , vol.119 , pp. 39-51
    • Zhao, J.1    Chen, G.2    Cao, D.3    Li, Y.4    Diao, F.5    Cai, H.6    Jin, Y.7    Lu, J.8
  • 33
    • 45549096766 scopus 로고    scopus 로고
    • Cancer stem cells: A step toward the cure
    • Boman BM and Wicha MS: Cancer stem cells: a step toward the cure. J Clin Oncol 26: 2795-2799, 2008.
    • (2008) J Clin Oncol , vol.26 , pp. 2795-2799
    • Boman, B.M.1    Wicha, M.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.