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Volumn 47, Issue 3, 2011, Pages 109-117

Meloxicam, a COX-2 inhibitor, ameliorates ischemia/reperfusion injury in non-heart-beating donor livers

Author keywords

COX 2 inhibition; Ischemia reperfusion injury; Liver preservation; Transplantation; Warm ischemia

Indexed keywords

ALANINE AMINOTRANSFERASE; BILE ACID; CYCLOOXYGENASE 2; GLUTAMATE LACTATE DEHYDROGENASE; LACTATE DEHYDROGENASE; MALONALDEHYDE; MELOXICAM; MESSENGER RNA; THROMBOXANE B2; UNCLASSIFIED DRUG;

EID: 79960257849     PISSN: 0014312X     EISSN: 14219921     Source Type: Journal    
DOI: 10.1159/000329414     Document Type: Article
Times cited : (11)

References (57)
  • 2
    • 6444241320 scopus 로고    scopus 로고
    • Liver transplantation from non-heart-beating donors: Current status and future prospects
    • DOI 10.1002/lt.20268
    • Reddy S, Zilvetti M, Brockmann J, McLaren A, Friend P: Liver transplantation from nonheart-beating donors: current status and future prospects. Liver Transpl 2004; 10: 1223-1232. (Pubitemid 39406075)
    • (2004) Liver Transplantation , vol.10 , Issue.10 , pp. 1223-1232
    • Reddy, S.1    Zilvetti, M.2    Brockmann, J.3    McLaren, A.4    Friend, P.J.5
  • 3
    • 0028838388 scopus 로고
    • Time is of the essence: The pressing need for comprehensive non-heart-beating cadaveric donation policies
    • Arnold RM, Youngner SJ: Time is of the essence: the pressing need for comprehensive non-heart-beating cadaveric donation policies. Transplant Proc 1995; 27: 2913-2917.
    • (1995) Transplant Proc , vol.27 , pp. 2913-2917
    • Arnold, R.M.1    Youngner, S.J.2
  • 4
    • 0030951513 scopus 로고    scopus 로고
    • The asystolic, or non-heartbeating, donor
    • DOI 10.1097/00007890-199704150-00001
    • Kootstra G: The asystolic, or non-heartbeating, donor. Transplantation 1997; 63: 917-921. (Pubitemid 27173009)
    • (1997) Transplantation , vol.63 , Issue.7 , pp. 917-921
    • Kootstra, G.1
  • 5
    • 0038012539 scopus 로고    scopus 로고
    • Liver transplantation from controlled non-heartbeating donors: An increased incidence of biliary complications
    • DOI 10.1097/01.TP.0000062574.18648.7C
    • Abt P, Crawford M, Desai N, Markmann J, Olthoff K, Shaked A: Liver transplantation from controlled non-heart-beating donors: an increased incidence of biliary complications. Transplantation 2003; 75: 1659-1663. (Pubitemid 36629146)
    • (2003) Transplantation , vol.75 , Issue.10 , pp. 1659-1663
    • Abt, P.1    Crawford, M.2    Desai, N.3    Markmann, J.4    Olthoff, K.5    Shaked, A.6
  • 8
    • 0033609165 scopus 로고    scopus 로고
    • Endothelial cell and hepatocyte deaths occur by apoptosis after ischemia-reperfusion injury in the rat liver
    • DOI 10.1097/00007890-199904270-00003
    • Kohli V, Selzner M, Madden JF, Bentley RC, Clavien PA: Endothelial cell and hepatocyte deaths occur by apoptosis after ischemia-reperfusion injury in the rat liver. Transplantation 1999; 67: 1099-1105. (Pubitemid 29205570)
    • (1999) Transplantation , vol.67 , Issue.8 , pp. 1099-1105
    • Kohli, V.1    Selzner, M.2    Madden, J.F.3    Bentley, R.C.4    Clavien, P.-A.5
  • 9
    • 0031778208 scopus 로고    scopus 로고
    • Apoptosis of sinusoidal endothelial cells is a critical mechanism of preservation injury in rat liver transplantation
    • DOI 10.1002/hep.510270626
    • Gao W, Bentley RC, Madden JF, Clavien PA: Apoptosis of sinusoidal endothelial cells is a critical mechanism of preservation injury in rat liver transplantation. Hepatology 1998; 27: 1652-1660. (Pubitemid 28264691)
    • (1998) Hepatology , vol.27 , Issue.6 , pp. 1652-1660
    • Gao, W.1    Bentley, R.C.2    Madden, J.E.3    Clavien, P.-A.4
  • 10
    • 0029888972 scopus 로고    scopus 로고
    • Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis
    • Anderson GD, Hauser SD, McGarity KL, Bremer ME, Isakson PC, Gregory SA: Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis. J Clin Invest 1996; 97: 2672-2679. (Pubitemid 26187355)
    • (1996) Journal of Clinical Investigation , vol.97 , Issue.11 , pp. 2672-2679
    • Anderson, G.D.1    Hauser, S.D.2    McGarity, K.L.3    Bremer, M.E.4    Isakson, P.C.5    Gregory, S.A.6
  • 12
    • 0016905932 scopus 로고
    • Prostaglandins as mediators of inflammation
    • Vane JR: Prostaglandins as mediators of inflammation. Adv Prostaglandin Thromboxane Res 1976; 2: 791-801.
    • (1976) Adv Prostaglandin Thromboxane Res , vol.2 , pp. 791-801
    • Vane, J.R.1
  • 14
    • 0029923087 scopus 로고    scopus 로고
    • Differential regulation of cyclo-oxygenase-1 and cyclo-oxygenase-2 gene expression by lipopolysaccharide treatment in vivo in the rat
    • Liu SF, Newton R, Evans TW, Barnes PJ: Differential regulation of cyclo-oxygenase-1 and cyclo-oxygenase-2 gene expression by lipopolysaccharide treatment in vivo in the rat. Clin Sci (Lond) 1996; 90: 301-306.
    • (1996) Clin Sci (Lond) , vol.90 , pp. 301-306
    • Liu, S.F.1    Newton, R.2    Evans, T.W.3    Barnes, P.J.4
  • 16
    • 0028787224 scopus 로고
    • Cyclooxygenase-2: Regulation and relevance in inflammation
    • Mitchell JA, Larkin S, Williams TJ: Cyclooxygenase-2: regulation and relevance in inflammation. Biochem Pharmacol 1995; 50: 1535-1542.
    • (1995) Biochem Pharmacol , vol.50 , pp. 1535-1542
    • Mitchell, J.A.1    Larkin, S.2    Williams, T.J.3
  • 18
    • 0028842742 scopus 로고
    • Prostaglandin endoperoxide synthases-1 and-2
    • Otto JC, Smith WL: Prostaglandin endoperoxide synthases-1 and-2. J Lipid Mediat Cell Signal 1995; 12: 139-156.
    • (1995) J Lipid Mediat Cell Signal , vol.12 , pp. 139-156
    • Otto, J.C.1    Smith, W.L.2
  • 19
    • 0028814935 scopus 로고
    • Differential measurement of constitutive (COX-1) and inducible (COX-2) cyclooxygenase expression in human umbilical vein endothelial cells using specific immunometric enzyme immunoassays
    • Creminon C, Habib A, Maclouf J, Pradelles P, Grassi J, Frobert Y: Differential measurement of constitutive (COX-1) and inducible (COX-2) cyclooxygenase expression in human umbilical vein endothelial cells using specific immunometric enzyme immunoassays. Biochim Biophys Acta 1995; 1254: 341-348.
    • (1995) Biochim Biophys Acta , vol.1254 , pp. 341-348
    • Creminon, C.1    Habib, A.2    MacLouf, J.3    Pradelles, P.4    Grassi, J.5    Frobert, Y.6
  • 21
    • 0031838354 scopus 로고    scopus 로고
    • Peptidergic and cholinergic neurons and mediators in peptoneinduced gastroprotection: Role of cyclooxygenase-2
    • Ehrlich K, Plate S, Stroff T, Gretzer B, Respondek M, Peskar BM: Peptidergic and cholinergic neurons and mediators in peptoneinduced gastroprotection: role of cyclooxygenase-2. Am J Physiol 1998; 274(5 Pt 1): G955-G964.
    • (1998) Am J Physiol , vol.274 , Issue.5 PART 1
    • Ehrlich, K.1    Plate, S.2    Stroff, T.3    Gretzer, B.4    Respondek, M.5    Peskar, B.M.6
  • 22
    • 0025005862 scopus 로고
    • The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes
    • FU JY, Masferrer JL, Seibert K, Raz A, Needleman P: The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes. J Biol Chem 1990; 265: 16737-16740.
    • (1990) J Biol Chem , vol.265 , pp. 16737-16740
    • Jy, F.U.1    Masferrer, J.L.2    Seibert, K.3    Raz, A.4    Needleman, P.5
  • 23
    • 0031081781 scopus 로고    scopus 로고
    • 2 and by cyclooxygenase inhibitors
    • DOI 10.1002/(SICI)1098-1136(199702)19:2<152::AID-GLIA6>3.0.CO;2-2
    • Minghetti L, Nicolini A, Polazzi E, Creminon C, Maclouf J, Levi G: Inducible nitric oxide synthase expression in activated rat microglial cultures is downregulated by exogenous prostaglandin E2 and by cyclooxygenase inhibitors. Glia 1997; 19: 152-160. (Pubitemid 27094132)
    • (1997) GLIA , vol.19 , Issue.2 , pp. 152-160
    • Minghetti, L.1    Nicolini, A.2    Polazzi, E.3    Creminon, C.4    Maclouf, J.5    Levi, G.6
  • 24
    • 0032167857 scopus 로고    scopus 로고
    • Interaction between inducible nitric oxide synthase and cyclooxygenase-after cerebral ischemia
    • Nogawa S, Forster C, Zhang F, Nagayama M, Ross ME, Iadecola C: Interaction between inducible nitric oxide synthase and cyclooxygenase-after cerebral ischemia. Proc Natl Acad Sci USA 1998; 95: 10966-10971.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 10966-10971
    • Nogawa, S.1    Forster, C.2    Zhang, F.3    Nagayama, M.4    Ross, M.E.5    Iadecola, C.6
  • 25
    • 0031902251 scopus 로고    scopus 로고
    • Cyclooxygenase 2 is induced in colonic epithelial cells in inflammatory bowel disease
    • DOI 10.1016/S0016-5085(98)70196-9
    • Singer II, Kawka DW, Schloemann S, Tessner T, Riehl T, Stenson WF: Cyclooxygenase 2 is induced in colonic epithelial cells in inflammatory bowel disease. Gastroenterology 1998; 115: 297-306. (Pubitemid 28363422)
    • (1998) Gastroenterology , vol.115 , Issue.2 , pp. 297-306
    • Singer, I.I.1    Kawka, D.W.2    Schloemann, S.3    Tessner, T.4    Riehl, T.5    Stenson, W.F.6
  • 26
    • 0028954821 scopus 로고
    • Expression and role of cyclooxygenase isoforms in alveolar and peritoneal macrophages
    • Wilborn J, DeWitt DL, Peters-Golden M: Expression and role of cyclooxygenase isoforms in alveolar and peritoneal macrophages. Am J Physiol 1995; 268(2 Pt 1):L294-L301.
    • (1995) Am J Physiol , vol.268 , Issue.2 PART 1
    • Wilborn, J.1    Dewitt, D.L.2    Peters-Golden, M.3
  • 27
    • 0030826370 scopus 로고    scopus 로고
    • 2. Distinct roles of cyclooxygenase-1 and -2
    • DOI 10.1074/jbc.272.41.25693
    • Williams JA, Shacter E: Regulation of macrophage cytokine production by prostaglandin E2. Distinct roles of cyclooxygenase-1 and-2. J Biol Chem 1997; 272: 25693-25699. (Pubitemid 27438886)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.41 , pp. 25693-25699
    • Williams, J.A.1    Shacter, E.2
  • 29
    • 0033510313 scopus 로고    scopus 로고
    • The cyclooxygenase-2 inhibitor NS-398 ameliorates ischemic brain injury in wild-type mice but not in mice with deletion of the inducible nitric oxide synthase gene
    • Nagayama M, Niwa K, Nagayama T, Ross ME, Iadecola C: The cyclooxygenase-2 inhibitor NS-398 ameliorates ischemic brain injury in wild-type mice but not in mice with deletion of the inducible nitric oxide synthase gene. J Cereb Blood Flow Metab 1999; 19: 1213-1219. (Pubitemid 30176449)
    • (1999) Journal of Cerebral Blood Flow and Metabolism , vol.19 , Issue.11 , pp. 1213-1219
    • Nagayama, M.1    Niwa, K.2    Nagayama, T.3    Ross, M.E.4    Iadecola, C.5
  • 30
    • 34447327780 scopus 로고    scopus 로고
    • Effects of the COX-2 inhibitor FK3311 on ischemia - Reperfusion injury in the rat lung
    • DOI 10.1080/08941930701365986, PII 779874173
    • Otani Y, Takeyoshi I, Yoshinari D, Matsumoto K, Morishita Y: Effects of the COX-2 inhibitor FK3311 on ischemia-reperfusion injury in the rat lung. J Invest Surg 2007; 20: 175-180. (Pubitemid 47050380)
    • (2007) Journal of Investigative Surgery , vol.20 , Issue.3 , pp. 175-180
    • Otani, Y.1    Takeyoshi, I.2    Yoshinari, D.3    Matsumoto, K.4    Morishita, Y.5
  • 34
    • 73949092457 scopus 로고    scopus 로고
    • The effects of cyclooxygenase (COX)-2 inhibition on ischemia-reperfusion injury in liver transplantation
    • Oshima K, Yabata Y, Yoshinari D, Takeyoshi I: The effects of cyclooxygenase (COX)-2 inhibition on ischemia-reperfusion injury in liver transplantation. J Invest Surg 2009; 22: 239-245.
    • (2009) J Invest Surg , vol.22 , pp. 239-245
    • Oshima, K.1    Yabata, Y.2    Yoshinari, D.3    Takeyoshi, I.4
  • 36
    • 31344476480 scopus 로고    scopus 로고
    • The effect of celecoxib, a selective COX-2 inhibitor, on liver ischemia/reperfusion-induced oxidative stress in rats
    • DOI 10.1016/j.hepres.2005.11.003, PII S1386634605004341
    • Ozturk H, Gezici A, Ozturk H: The effect of celecoxib, a selective COX-2 inhibitor, on liver ischemia/reperfusion-induced oxidative stress in rats. Hepatol Res 2006; 34: 76-83. (Pubitemid 43137555)
    • (2006) Hepatology Research , vol.34 , Issue.2 , pp. 76-83
    • Ozturk, H.1    Gezici, A.2    Ozturk, H.3
  • 37
    • 0042386436 scopus 로고    scopus 로고
    • Effects of selective cyclooxygenase inhibitors on ischemia/reperfusion- induced hepatic microcirculatory dysfunction in mice
    • DOI 10.1159/000072174
    • Ito Y, Katagiri H, Ishii K, Kakita A, Hayashi I, Majima M: Effects of selective cyclooxygenase inhibitors on ischemia/reperfusion-induced hepatic microcirculatory dysfunction in mice. Eur Surg Res 2003; 35: 408-416. (Pubitemid 37034391)
    • (2003) European Surgical Research , vol.35 , Issue.5 , pp. 408-416
    • Ito, Y.1    Katagiri, H.2    Ishii, K.3    Kakita, A.4    Hayashi, I.5    Majima, M.6
  • 38
    • 0029619752 scopus 로고
    • Meloxicam: A potent inhibitor of adjuvant arthritis in the Lewis rat
    • DOI 10.1007/BF01757360
    • Engelhardt G, Homma D, Schnitzler C: Meloxicam: a potent inhibitor of adjuvant arthritis in the Lewis rat. Inflamm Res 1995; 44: 548-555. (Pubitemid 26008751)
    • (1995) Inflammation Research , vol.44 , Issue.12 , pp. 548-555
    • Engelhardt, G.1    Homma, D.2    Schnitzler, C.3
  • 39
    • 0030061289 scopus 로고    scopus 로고
    • Meloxicam: Influence on arachidonic acid metabolism. Part II. in vivo findings
    • Engelhardt G, Bogel R, Schnitzler C, Utzmann R: Meloxicam: influence on arachidonic acid metabolism. Part II. In vivo findings. Biochem Pharmacol 1996; 51: 29-38.
    • (1996) Biochem Pharmacol , vol.51 , pp. 29-38
    • Engelhardt, G.1    Bogel, R.2    Schnitzler, C.3    Utzmann, R.4
  • 40
    • 0031813031 scopus 로고    scopus 로고
    • Differential inhibition of cyclooxygenases-1 and -2 by meloxicam and its 4'-isomer
    • DOI 10.1007/s000110050329
    • Pairet M, van Ryn J, Schierok H, Mauz A, Trummlitz G, Engelhardt G: Differential inhibition of cyclooxygenases-1 and-2 by meloxicam and its 4f-isomer. Inflamm Res 1998; 47: 270-276. (Pubitemid 28325586)
    • (1998) Inflammation Research , vol.47 , Issue.6 , pp. 270-276
    • Pairet, M.1    Van Ryn, J.2    Schierok, H.3    Mauz, A.4    Trummlitz, G.5    Engelhardt, G.6
  • 43
    • 0033973312 scopus 로고    scopus 로고
    • Cold preservation of fatty liver grafts: Prevention of functional and ultrastructural impairments by venous oxygen persufflation
    • Minor T, Akbar S, Tolba R, Dombrowski F: Cold preservation of fatty liver grafts: prevention of functional and ultrastructural impairments by venous oxygen persufflation. J Hepatol 2000; 32: 105-111. (Pubitemid 30039454)
    • (2000) Journal of Hepatology , vol.32 , Issue.1 , pp. 105-111
    • Minor, T.1    Akbar, S.2    Tolba, R.3    Dombrowski, F.4
  • 44
    • 0343673978 scopus 로고    scopus 로고
    • Gaseous oxygen for hypothermic preservation of predamaged liver grafts: Fuel to cellular homeostasis or radical tissue alteration?
    • DOI 10.1006/cryo.2000.2231
    • Minor T, Kotting M: Gaseous oxygen for hypothermic preservation of predamaged liver grafts: fuel to cellular homeostasis or radical tissue alteration? Cryobiology 2000; 40: 182-186. (Pubitemid 30314265)
    • (2000) Cryobiology , vol.40 , Issue.2 , pp. 182-186
    • Minor, T.1    Kotting, M.2
  • 47
    • 0035958191 scopus 로고    scopus 로고
    • Fibrinolytic preflush upon liver retrieval from non-heart beating donors to enhance postpreservation viability and energetic recovery upon reperfusion
    • Minor T, Hachenberg A, Tolba R, Pauleit D, Akbar S: Fibrinolytic preflush upon liver retrieval from non-heart beating donors to enhance postpreservation viability and energetic recovery upon reperfusion. Transplantation 2001; 71: 1792-1796. (Pubitemid 32622492)
    • (2001) Transplantation , vol.71 , Issue.12 , pp. 1792-1796
    • Minor, T.1    Hachenberg, A.2    Tolba, R.3    Pauleit, D.4    Akbar, S.5
  • 48
    • 0023272639 scopus 로고
    • Bile flow - An index of ischemic injury
    • DOI 10.1016/0022-4804(87)90033-3
    • Bowers BA, Branum GD, Rotolo FS, Watters CR, Meyers WC: Bile flow-an index of ischemic injury. J Surg Res 1987; 42: 565-569. (Pubitemid 17091906)
    • (1987) Journal of Surgical Research , vol.42 , Issue.5 , pp. 565-569
    • Bowers, B.A.1    Branum, G.D.2    Rotolo, F.S.3
  • 49
    • 0026751233 scopus 로고
    • Preservation and reperfusion injuries in liver allografts. An overview and synthesis of current studies
    • Clavien PA, Harvey PR, Strasberg SM: Preservation and reperfusion injuries in liver allografts. An overview and synthesis of current studies. Transplantation 1992; 53: 957-978.
    • (1992) Transplantation , vol.53 , pp. 957-978
    • Clavien, P.A.1    Harvey, P.R.2    Strasberg, S.M.3
  • 50
    • 0025735957 scopus 로고
    • Microcirculatory disturbances and leucocyte adherence in transplanted livers after cold storage in Euro-Collins, UW and HTK solutions
    • Marzi I, Walcher F, Menger M, Buhren V, Harbauer G, Trentz O: Microcirculatory disturbances and leucocyte adherence in transplanted livers after cold storage in Euro-Collins, UW and HTK solutions. Transpl Int 1991; 4: 45-50.
    • (1991) Transpl Int , vol.4 , pp. 45-50
    • Marzi, I.1    Walcher, F.2    Menger, M.3    Buhren, V.4    Harbauer, G.5    Trentz, O.6
  • 51
    • 0026351369 scopus 로고
    • Role of oxygen radicals in the microcirculatory manifestations of postischemic injury
    • Menger MD, Lehr HA, Messmer K: Role of oxygen radicals in the microcirculatory manifestations of postischemic injury. Klin Wochenschr 1991; 69: 1050-1055.
    • (1991) Klin Wochenschr , vol.69 , pp. 1050-1055
    • Menger, M.D.1    Lehr, H.A.2    Messmer, K.3
  • 52
    • 0025756580 scopus 로고
    • Neutrophil and Kupffer cell-induced oxidant stress and ischemia-reperfusion injury in rat liver
    • Jaeschke H, Farhood A: Neutrophil and Kupffer cell-induced oxidant stress and ischemia-reperfusion injury in rat liver. Am J Physiol 1991; 260(3 Pt 1):G355-G362.
    • (1991) Am J Physiol , vol.260 , Issue.3 PART 1
    • Jaeschke, H.1    Farhood, A.2
  • 53
    • 1842329163 scopus 로고    scopus 로고
    • Mechanisms of neutrophil-induced parenchymal cell injury
    • Jaeschke H, Smith CW: Mechanisms of neutrophil-induced parenchymal cell injury. J Leukoc Biol 1997; 61: 647-653. (Pubitemid 27276056)
    • (1997) Journal of Leukocyte Biology , vol.61 , Issue.6 , pp. 647-653
    • Jaeschke, H.1    Smith, C.W.2
  • 54
    • 4544331729 scopus 로고    scopus 로고
    • Antithrombin reduces ischemia/reperfusion-induced liver injury in rats by activation of cyclooxygenase-I
    • DOI 10.1160/TH03-07-0460
    • Harada N, Okajima K, Uchiba M, Kushimoto S, Isobe H: Antithrombin reduces ischemia/reperfusion-induced liver injury in rats by activation of cyclooxygenase-1. Thromb Haemost 2004; 92: 550-558. (Pubitemid 39248011)
    • (2004) Thrombosis and Haemostasis , vol.92 , Issue.3 , pp. 550-558
    • Harada, N.1    Okajima, K.2    Uchiba, M.3    Kushimoto, S.4    Isobe, H.5
  • 55
    • 0029844689 scopus 로고    scopus 로고
    • 1 to improve lung preservation
    • Naka Y, Roy DK, Liao H, Chowdhury NC, Michler RE, Oz MC, Pinsky DJ: cAMP-mediated vascular protection in an orthotopic rat lung transplant model. Insights into the mechanism of action of prostaglandin E1 to improve lung preservation. Circ Res 1996; 79: 773-783. (Pubitemid 26317825)
    • (1996) Circulation Research , vol.79 , Issue.4 , pp. 773-783
    • Naka, Y.1    Roy, D.K.2    Liao, H.3    Chowdhury, N.C.4    Michler, R.E.5    Oz, M.C.6    Pinsky, D.J.7


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