메뉴 건너뛰기




Volumn 51, Issue 1, 1996, Pages 29-38

Meloxican: Influence on arachidonic acid metabolism Part II. In vivo findings

Author keywords

In vivo; Leucotrienes; Meloxicam; Prostaglandins; Thromboxane

Indexed keywords

ACETYLSALICYLIC ACID; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DEXAMETHASONE; DICLOFENAC; DIPYRONE; FLURBIPROFEN; INDOMETACIN; LEUKOTRIENE B4; LEUKOTRIENE C4; MELOXICAM; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; PARACETAMOL; PIROXICAM; PROSTAGLANDIN E2; TENIDAP; TENOXICAM; THROMBOXANE B2;

EID: 0030061289     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(95)02110-8     Document Type: Article
Times cited : (138)

References (48)
  • 1
    • 0028860983 scopus 로고
    • Anti-inflammatory, analgesic, antipyretic and related properties of meloxicam, a new nonsteroidal anti-inflammatory agent
    • Engelhardt G, Homma D, Schlegel K, Schnitzler Chr and Utzmann R, Anti-inflammatory, analgesic, antipyretic and related properties of meloxicam, a new nonsteroidal anti-inflammatory agent. Inflamm Res 44: 423-433, 1995.
    • (1995) Inflamm Res , vol.44 , pp. 423-433
    • Engelhardt, G.1    Homma, D.2    Schlegel, K.3    Schnitzler, Chr.4    Utzmann, R.5
  • 2
    • 0012073092 scopus 로고
    • Meloxicam, a potent inhibitor of adjuvant arthritis in the rat
    • Abstr. No. 110
    • Engelhardt G, Meloxicam, a potent inhibitor of adjuvant arthritis in the rat. Scand J Rheumatol 98: (Suppl) Abstr. No. 110, 1994.
    • (1994) Scand J Rheumatol , vol.98 , Issue.SUPPL.
    • Engelhardt, G.1
  • 3
    • 0015237292 scopus 로고
    • Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
    • Vane JR, Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nature New Biol 231: 232-235, 1971.
    • (1971) Nature New Biol , vol.231 , pp. 232-235
    • Vane, J.R.1
  • 4
    • 0004428513 scopus 로고
    • Mode of action of aspirin and similar compounds
    • (Eds. Robinson HJ and Vane JR), Raven Press, New York
    • Vane JR, Mode of action of aspirin and similar compounds. In: Prostaglandin Synthetase Inhibitors (Eds. Robinson HJ and Vane JR), pp. 155-163. Raven Press, New York, 1974.
    • (1974) Prostaglandin Synthetase Inhibitors , pp. 155-163
    • Vane, J.R.1
  • 5
    • 0001208476 scopus 로고
    • Temporal and pharmacological division of fibroblast cyclooxygenase expression into transcriptional and translational phases
    • Raz A, Wyche A and Needleman P, Temporal and pharmacological division of fibroblast cyclooxygenase expression into transcriptional and translational phases. Proc Natl Acad Sci USA 86: 1657-1661, 1989.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 1657-1661
    • Raz, A.1    Wyche, A.2    Needleman, P.3
  • 6
    • 0025754779 scopus 로고
    • Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by RNA splicing
    • Xie W, Chipman JG, Robertson DL, Erikson RC and Simmons DL, Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by RNA splicing. Proc Natl Acad Sci USA 88: 2692-2696, 1991.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 2692-2696
    • Xie, W.1    Chipman, J.G.2    Robertson, D.L.3    Erikson, R.C.4    Simmons, D.L.5
  • 7
    • 0017094798 scopus 로고
    • An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation
    • Moncada S, Grygliewski R, Bunting S and Vane JR, An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation. Nature 263: 663-665, 1976.
    • (1976) Nature , vol.263 , pp. 663-665
    • Moncada, S.1    Grygliewski, R.2    Bunting, S.3    Vane, J.R.4
  • 8
    • 0027146692 scopus 로고
    • Selectivity of nonsteroidal anti-inflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase
    • Mitchell JA, Akarasereenont P, Thiemerman C, Flower R and Vane JR, Selectivity of nonsteroidal anti-inflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc Natl Acad Sci USA 90: 11693-11697, 1994.
    • (1994) Proc Natl Acad Sci USA , vol.90 , pp. 11693-11697
    • Mitchell, J.A.1    Akarasereenont, P.2    Thiemerman, C.3    Flower, R.4    Vane, J.R.5
  • 9
    • 0028044609 scopus 로고
    • Towards a better aspirin
    • Vane J, Towards a better aspirin. Nature 367: 215-216, 1994.
    • (1994) Nature , vol.367 , pp. 215-216
    • Vane, J.1
  • 10
    • 0027480087 scopus 로고
    • Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other nonsteroidal anti-inflammatory drugs
    • Meade EA, Smith WL and DeWitt DL, Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other nonsteroidal anti-inflammatory drugs. J Biol Chem 268: 6610-6614, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 6610-6614
    • Meade, E.A.1    Smith, W.L.2    DeWitt, D.L.3
  • 11
    • 0024452740 scopus 로고
    • A review of gastric ulcer and gastroduodenal injury in normal volunteers receiving aspirin and other nonsteroidal anti-inflammatory drugs
    • Lanza FL, A review of gastric ulcer and gastroduodenal injury in normal volunteers receiving aspirin and other nonsteroidal anti-inflammatory drugs. Scand J Gastroenterol 24: 24-31, 1989.
    • (1989) Scand J Gastroenterol , vol.24 , pp. 24-31
    • Lanza, F.L.1
  • 12
    • 0028327671 scopus 로고
    • Risk of upper gastrointestinal bleeding and perforation associated with individual non-steroidal anti-inflammatory drugs
    • Garcia Rodriguez LA and Jick H, Risk of upper gastrointestinal bleeding and perforation associated with individual non-steroidal anti-inflammatory drugs. Lancet 343: 769-772, 1994.
    • (1994) Lancet , vol.343 , pp. 769-772
    • Garcia Rodriguez, L.A.1    Jick, H.2
  • 13
    • 0015879324 scopus 로고
    • Some quantitative temporal characteristics of carrageenin-induced pleurisy in the rat
    • Vinegar R, Tonax JF and Selph JL, Some quantitative temporal characteristics of carrageenin-induced pleurisy in the rat. Proc Soc Exp Biol Med 143: 711-714, 1973.
    • (1973) Proc Soc Exp Biol Med , vol.143 , pp. 711-714
    • Vinegar, R.1    Tonax, J.F.2    Selph, J.L.3
  • 16
    • 0000063441 scopus 로고
    • A fundamental formula in the statistics of biological assay, and some applications
    • Fieller EC, A fundamental formula in the statistics of biological assay, and some applications. Q J Pharm Pharmacol 17: 117-125, 1944.
    • (1944) Q J Pharm Pharmacol , vol.17 , pp. 117-125
    • Fieller, E.C.1
  • 17
    • 0019350396 scopus 로고
    • Lowering of the convulsive threshold by nonsteroidal anti-inflammatory drugs
    • Steinhauer HB and Hertting G, Lowering of the convulsive threshold by nonsteroidal anti-inflammatory drugs. Eur J Pharmacol 69: 199-205, 1981.
    • (1981) Eur J Pharmacol , vol.69 , pp. 199-205
    • Steinhauer, H.B.1    Hertting, G.2
  • 18
    • 0025005862 scopus 로고
    • The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes
    • Fu JY, Masferrer JL, Seibert K, Raz A and Needleman P, The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes. J Biol Chem 265: 16737-16740, 1990.
    • (1990) J Biol Chem , vol.265 , pp. 16737-16740
    • Fu, J.Y.1    Masferrer, J.L.2    Seibert, K.3    Raz, A.4    Needleman, P.5
  • 19
    • 0026662385 scopus 로고
    • Dexamethasone inhibits mitogen induction of the TIS 10 prostaglandin synthase cyclooxygenase gene
    • Kujubu DA and Herschman HR, Dexamethasone inhibits mitogen induction of the TIS 10 prostaglandin synthase cyclooxygenase gene. J Biol Chem 267: 7991-7994, 1992.
    • (1992) J Biol Chem , vol.267 , pp. 7991-7994
    • Kujubu, D.A.1    Herschman, H.R.2
  • 21
    • 0025187588 scopus 로고
    • Selective regulation of cellular cyclooxygenase by dexamethasone and endotoxin in mice
    • Masferrer JL, Zweifel BS, Seibert K and Needleman P, Selective regulation of cellular cyclooxygenase by dexamethasone and endotoxin in mice. J Clin Incest 86: 1375-1379, 1990.
    • (1990) J Clin Incest , vol.86 , pp. 1375-1379
    • Masferrer, J.L.1    Zweifel, B.S.2    Seibert, K.3    Needleman, P.4
  • 23
    • 85029991266 scopus 로고
    • The induction of a second and different cyclooxygenase is important in inflammation
    • Sept. 28-29, London Abstr.
    • Vane JR, The induction of a second and different cyclooxygenase is important in inflammation. In: William Harvey Res Conf, Sept. 28-29, London 1992, Vol. 3, Abstr. p. 3.
    • (1992) William Harvey Res Conf , vol.3 , pp. 3
    • Vane, J.R.1
  • 24
    • 0028926813 scopus 로고
    • New insights into the mode of action of anti-inflammatory drugs
    • Vane JR and Botting RM, New insights into the mode of action of anti-inflammatory drugs. Inflamm Res 44: 1-10, 1995.
    • (1995) Inflamm Res , vol.44 , pp. 1-10
    • Vane, J.R.1    Botting, R.M.2
  • 26
    • 0020672513 scopus 로고
    • The eicosanoids of asthma
    • Weissmann G, The eicosanoids of asthma. N Engl J Med 308: 454-455, 1983.
    • (1983) N Engl J Med , vol.308 , pp. 454-455
    • Weissmann, G.1
  • 27
    • 0025973735 scopus 로고
    • Inhibition of 5-lipoxygenase product formation and polymorphonuclear cell degranulation by tenidap sodium in patients with rheumatoid arthritis
    • Blackburn WD, Heck LW, Loose LD, Eskra JD and Carty TJ, Inhibition of 5-lipoxygenase product formation and polymorphonuclear cell degranulation by tenidap sodium in patients with rheumatoid arthritis. Arthritis Rheum 34: 204-210, 1991.
    • (1991) Arthritis Rheum , vol.34 , pp. 204-210
    • Blackburn, W.D.1    Heck, L.W.2    Loose, L.D.3    Eskra, J.D.4    Carty, T.J.5
  • 28
    • 0026443983 scopus 로고
    • NSAIDs, ulcers and prostaglandins
    • Kimmey MB, NSAIDs, ulcers and prostaglandins. J Rheumatol 19, Suppl 36, 68-73, 1992.
    • (1992) J Rheumatol , vol.19 , Issue.SUPPL. 36 , pp. 68-73
    • Kimmey, M.B.1
  • 29
    • 0027252475 scopus 로고
    • Are systemic levels of non steroidal anti-inflammatory drugs relevant to acute upper gastrointestinal haemorrhage?
    • Wynne HA and Rawlins MD, Are systemic levels of non steroidal anti-inflammatory drugs relevant to acute upper gastrointestinal haemorrhage? Eur J Clin Pharmacol 44: 309-313, 1993.
    • (1993) Eur J Clin Pharmacol , vol.44 , pp. 309-313
    • Wynne, H.A.1    Rawlins, M.D.2
  • 30
    • 0021701756 scopus 로고
    • A biochemical basis for the gastrointestinal toxicity of nonsteroidal anti-rheumatoid drugs
    • Whittle BJR and Vane JR, A biochemical basis for the gastrointestinal toxicity of nonsteroidal anti-rheumatoid drugs. Arch Toxicol Suppl. 7, 315-322, 1984.
    • (1984) Arch Toxicol Suppl. , vol.7 , pp. 315-322
    • Whittle, B.J.R.1    Vane, J.R.2
  • 31
    • 0023697639 scopus 로고
    • Prevention of NSAID-induced gastric ulcer with synthetic prostaglandin, misoprostol: Multicentre double-blind placebo controlled trial
    • Graham DY, Agraval NM and Roth SH, Prevention of NSAID-induced gastric ulcer with synthetic prostaglandin, misoprostol: multicentre double-blind placebo controlled trial. Lancet 2: 1277-1280, 1988.
    • (1988) Lancet , vol.2 , pp. 1277-1280
    • Graham, D.Y.1    Agraval, N.M.2    Roth, S.H.3
  • 32
    • 0025997453 scopus 로고
    • Mechanisms of gastric mucosal injury and protection
    • Szabo S, Mechanisms of gastric mucosal injury and protection. J Clin Gastroenterol 13: S21-S24, 1991.
    • (1991) J Clin Gastroenterol , vol.13
    • Szabo, S.1
  • 33
    • 0018904225 scopus 로고
    • Selective inhibition of prostaglandin production in inflammatory exudates and gastric mucosa
    • Whittle BJR, Higgs GA, Eakins KE, Moncada S and Vane JR, Selective inhibition of prostaglandin production in inflammatory exudates and gastric mucosa. Nature 284: 271-273, 1980.
    • (1980) Nature , vol.284 , pp. 271-273
    • Whittle, B.J.R.1    Higgs, G.A.2    Eakins, K.E.3    Moncada, S.4    Vane, J.R.5
  • 34
    • 0023883941 scopus 로고
    • Effect of a new anti-inflammatory compound, CGP 28237, on arachidonate metabolism in rat gastrointestinal tissue
    • Green JR, Böttcher I and Peskar BA, Effect of a new anti-inflammatory compound, CGP 28237, on arachidonate metabolism in rat gastrointestinal tissue. Agents Actions 23: 110-111, 1988.
    • (1988) Agents Actions , vol.23 , pp. 110-111
    • Green, J.R.1    Böttcher, I.2    Peskar, B.A.3
  • 35
    • 0023028158 scopus 로고
    • A subchronic study of the effect of etodolac on the gastric mucosal prostaglandin levels in the rat
    • Lee DKH, Cohen R, Gilliar J, Mulder B and Smith T, A subchronic study of the effect of etodolac on the gastric mucosal prostaglandin levels in the rat. Agents Actions 19: 228-232, 1986.
    • (1986) Agents Actions , vol.19 , pp. 228-232
    • Lee, D.K.H.1    Cohen, R.2    Gilliar, J.3    Mulder, B.4    Smith, T.5
  • 36
    • 0022341735 scopus 로고
    • Etodolac: Effect on prostaglandin concentrations in gastric mucosa of rats
    • Lee D and Dvornik D, Etodolac: effect on prostaglandin concentrations in gastric mucosa of rats. Life Sci 36: 1157-1162, 1985.
    • (1985) Life Sci , vol.36 , pp. 1157-1162
    • Lee, D.1    Dvornik, D.2
  • 37
    • 0023010914 scopus 로고
    • Effects of salicylic and acetylsalicylic acid alone and in combination on platelet aggregation and prostanoid synthesis in man
    • Rosenkranz B, Fischer C, Meese CO and Frölich JC, Effects of salicylic and acetylsalicylic acid alone and in combination on platelet aggregation and prostanoid synthesis in man. Br J Clin Pharmacol 21: 309-317, 1986.
    • (1986) Br J Clin Pharmacol , vol.21 , pp. 309-317
    • Rosenkranz, B.1    Fischer, C.2    Meese, C.O.3    Frölich, J.C.4
  • 38
    • 0020398738 scopus 로고
    • In vitro prostaglandin synthesis by human glomeruli and papillae
    • Sraer J, Ardaillon N, Sraer JD and Ardaillon R, In vitro prostaglandin synthesis by human glomeruli and papillae. Prostaglandins 23: 855-864, 1982.
    • (1982) Prostaglandins , vol.23 , pp. 855-864
    • Sraer, J.1    Ardaillon, N.2    Sraer, J.D.3    Ardaillon, R.4
  • 40
    • 0025275548 scopus 로고
    • Effects of acetylsalicyclic acid and paracetamol alone and in combination on prostanoid synthesis in man
    • Bippi H and Frölich JC, Effects of acetylsalicyclic acid and paracetamol alone and in combination on prostanoid synthesis in man. Br J Clin Pharmacol 29: 305-310, 1990.
    • (1990) Br J Clin Pharmacol , vol.29 , pp. 305-310
    • Bippi, H.1    Frölich, J.C.2
  • 41
    • 0026332608 scopus 로고
    • Die nierenfunktion unter therapie mit nichtsteroidalen antiphlogistika
    • Lang B, Hank P, Meske S, Keller E and Peter HH, Die Nierenfunktion unter Therapie mit nichtsteroidalen Antiphlogistika. Z Rheumatol 50: 366-370, 1991.
    • (1991) Z Rheumatol , vol.50 , pp. 366-370
    • Lang, B.1    Hank, P.2    Meske, S.3    Keller, E.4    Peter, H.H.5
  • 43
    • 0025282685 scopus 로고
    • The comparative effects of paracetamol and indomethacin on renal function in healthy female volunteers
    • Prescott LF, Mattison P, Menzies DG and Manson LM, The comparative effects of paracetamol and indomethacin on renal function in healthy female volunteers. Br J Clin Pharmacol 29: 403-412, 1990.
    • (1990) Br J Clin Pharmacol , vol.29 , pp. 403-412
    • Prescott, L.F.1    Mattison, P.2    Menzies, D.G.3    Manson, L.M.4
  • 44
    • 0021352405 scopus 로고
    • Renal syndromes associated with nonsteroidal anti-inflammatory drugs
    • Clive DM and Stoff JS, Renal syndromes associated with nonsteroidal anti-inflammatory drugs. N Engl J Med 310: 563-572, 1984.
    • (1984) N Engl J Med , vol.310 , pp. 563-572
    • Clive, D.M.1    Stoff, J.S.2
  • 45
    • 0021318261 scopus 로고
    • Nonsteroidal anti-inflammatory drugs and renal function
    • Dunn MJ, Nonsteroidal anti-inflammatory drugs and renal function. Ann Rev Med 35: 411-428, 1984.
    • (1984) Ann Rev Med , vol.35 , pp. 411-428
    • Dunn, M.J.1
  • 46
    • 0023251042 scopus 로고
    • Die bedeutung der renalen prostaglandine für die nierenfunktion im frühen kindesalter
    • Seyberth HW, Die Bedeutung der renalen Prostaglandine für die Nierenfunktion im frühen Kindesalter. Monatsschr Kinderheilk 135: 178-184, 1987.
    • (1987) Monatsschr Kinderheilk , vol.135 , pp. 178-184
    • Seyberth, H.W.1
  • 47
    • 0012049839 scopus 로고
    • The effects of indomethacin, ketoprofcn and piroxicam on basal and furosemide-induced sodium excretion in the healthy subject
    • (Eds. Rainsford KD and Velo GP), MTP Press Ltd, Lancaster
    • Sörgel F, Krankau J, Lang E, Braun J and Gessier U, The effects of indomethacin, ketoprofcn and piroxicam on basal and furosemide-induced sodium excretion in the healthy subject. In: Side Effects of Anti-inflammatory Drugs (Eds. Rainsford KD and Velo GP), MTP Press Ltd, Lancaster, 1985.
    • (1985) Side Effects of Anti-inflammatory Drugs
    • Sörgel, F.1    Krankau, J.2    Lang, E.3    Braun, J.4    Gessier, U.5
  • 48
    • 0027290813 scopus 로고
    • Expression of a mitogen-inducible cyclooxygenase in brain neurons: Regulation by synaptic activity and glucocorticoids
    • Yamagata K, Andreasson KJ, Kaufmann WE, Barnes CA and Worley PF, Expression of a mitogen-inducible cyclooxygenase in brain neurons: Regulation by synaptic activity and glucocorticoids. Neuron 11: 371-386, 1993.
    • (1993) Neuron , vol.11 , pp. 371-386
    • Yamagata, K.1    Andreasson, K.J.2    Kaufmann, W.E.3    Barnes, C.A.4    Worley, P.F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.