-
1
-
-
78651156947
-
Experimental evaluation of potential anticancer agents (XIII) on the criteria and kinetics associated with "curability" of experimental leukemia
-
H.E. Skipper, F.M. Schabel Jr., and W.S. Wilcox Experimental evaluation of potential anticancer agents (XIII) on the criteria and kinetics associated with "curability" of experimental leukemia Cancer Chemother Rep 35 1964 1
-
(1964)
Cancer Chemother Rep
, vol.35
, pp. 1
-
-
Skipper, H.E.1
Schabel, Jr.F.M.2
Wilcox, W.S.3
-
2
-
-
33846441659
-
Metronomic chemotherapy enhances the efficacy of antivascular therapy in ovarian cancer
-
A.A. Kamat, T.J. Kim, and C.N. Landen Jr. Metronomic chemotherapy enhances the efficacy of antivascular therapy in ovarian cancer Cancer Res 67 2007 281
-
(2007)
Cancer Res
, vol.67
, pp. 281
-
-
Kamat, A.A.1
Kim, T.J.2
Landen, Jr.C.N.3
-
3
-
-
0036897097
-
Protracted low-dose effects on human endothelial cell proliferation and survival in vitro reveal a selective anti-angiogenic window for various chemotherapeutic drugs
-
G. Bocci, K.C. Nicolaou, and R.S. Kerbel Protracted low-dose effects on human endothelial cell proliferation and survival in vitro reveal a selective anti-angiogenic window for various chemotherapeutic drugs Cancer Res 62 2002 6938
-
(2002)
Cancer Res
, vol.62
, pp. 6938
-
-
Bocci, G.1
Nicolaou, K.C.2
Kerbel, R.S.3
-
4
-
-
0037268220
-
Paclitaxel at ultra low concentrations inhibits angiogenesis without affecting cellular microtubule assembly
-
J. Wang, P. Lou, and R. Lesniewski Paclitaxel at ultra low concentrations inhibits angiogenesis without affecting cellular microtubule assembly Anticancer Drugs 14 2003 13
-
(2003)
Anticancer Drugs
, vol.14
, pp. 13
-
-
Wang, J.1
Lou, P.2
Lesniewski, R.3
-
5
-
-
0034087691
-
Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity
-
G. Klement, S. Baruchel, and J. Rak Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity J Clin Invest 105 2000 R15
-
(2000)
J Clin Invest
, vol.105
, pp. 15
-
-
Klement, G.1
Baruchel, S.2
Rak, J.3
-
6
-
-
0037093209
-
Antitumor effects in mice of low-dose (metronomic) cyclophosphamide administered continuously through the drinking water
-
S. Man, G. Bocci, and G. Francia Antitumor effects in mice of low-dose (metronomic) cyclophosphamide administered continuously through the drinking water Cancer Res 62 2002 2731
-
(2002)
Cancer Res
, vol.62
, pp. 2731
-
-
Man, S.1
Bocci, G.2
Francia, G.3
-
7
-
-
0034032882
-
Anti-angiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer
-
T. Browder, C.E. Butterfield, and B.M. Kraling Anti-angiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer Cancer Res 60 2000 1878
-
(2000)
Cancer Res
, vol.60
, pp. 1878
-
-
Browder, T.1
Butterfield, C.E.2
Kraling, B.M.3
-
8
-
-
0041589524
-
Maximum tolerable dose and low-dose metronomic chemotherapy have opposite effects on the mobilization and viability of circulating endothelial progenitor cells
-
F. Bertolini, S. Paul, and P. Mancuso Maximum tolerable dose and low-dose metronomic chemotherapy have opposite effects on the mobilization and viability of circulating endothelial progenitor cells Cancer Res 63 2003 4342
-
(2003)
Cancer Res
, vol.63
, pp. 4342
-
-
Bertolini, F.1
Paul, S.2
Mancuso, P.3
-
9
-
-
0035887463
-
Low-dose chemotherapy combined with an anti-angiogenic drug reduces human glioma growth in vivo
-
L. Bello, G. Carrabba, and C. Giussani Low-dose chemotherapy combined with an anti-angiogenic drug reduces human glioma growth in vivo Cancer Res 61 2001 7501
-
(2001)
Cancer Res
, vol.61
, pp. 7501
-
-
Bello, L.1
Carrabba, G.2
Giussani, C.3
-
10
-
-
0035206188
-
Novel use of an established agent: Topotecan is anti-angiogenic in experimental Wilms tumor
-
S.Z. Soffer, E. Kim, and J.T. Moore Novel use of an established agent: Topotecan is anti-angiogenic in experimental Wilms tumor J Pediatr Surg 36 2001 1781
-
(2001)
J Pediatr Surg
, vol.36
, pp. 1781
-
-
Soffer, S.Z.1
Kim, E.2
Moore, J.T.3
-
11
-
-
0036152447
-
Differences in therapeutic indexes of combination metronomic chemotherapy and an anti-VEGFR-2 antibody in multidrug-resistant human breast cancer xenografts
-
G. Klement, P. Huang, and B. Mayer Differences in therapeutic indexes of combination metronomic chemotherapy and an anti-VEGFR-2 antibody in multidrug-resistant human breast cancer xenografts Clin Cancer Res 8 2002 221
-
(2002)
Clin Cancer Res
, vol.8
, pp. 221
-
-
Klement, G.1
Huang, P.2
Mayer, B.3
-
12
-
-
0347626100
-
Synergistic effect of metronomic dosing of cyclophosphamide combined with specific antitumor immunotherapy in a murine melanoma model
-
I.F. Hermans, T.W. Chong, and M.J. Palmowski Synergistic effect of metronomic dosing of cyclophosphamide combined with specific antitumor immunotherapy in a murine melanoma model Cancer Res 63 2003 8408
-
(2003)
Cancer Res
, vol.63
, pp. 8408
-
-
Hermans, I.F.1
Chong, T.W.2
Palmowski, M.J.3
-
13
-
-
33744799963
-
Phase II clinical trial results involving treatment with low-dose daily oral cyclophosphamide, weekly vinblastine, and rofecoxib in patients with advanced solid tumors
-
S.D. Young, M. Whissell, and J.C. Noble Phase II clinical trial results involving treatment with low-dose daily oral cyclophosphamide, weekly vinblastine, and rofecoxib in patients with advanced solid tumors Clin Cancer Res 12 2006 3092
-
(2006)
Clin Cancer Res
, vol.12
, pp. 3092
-
-
Young, S.D.1
Whissell, M.2
Noble, J.C.3
-
14
-
-
0036225350
-
Low-dose oral methotrexate and cyclophosphamide in metastatic breast cancer: Antitumor activity and correlation with vascular endothelial growth factor levels
-
M. Colleoni, A. Rocca, and M.T. Sandri Low-dose oral methotrexate and cyclophosphamide in metastatic breast cancer: Antitumor activity and correlation with vascular endothelial growth factor levels Ann Oncol 13 2002 73
-
(2002)
Ann Oncol
, vol.13
, pp. 73
-
-
Colleoni, M.1
Rocca, A.2
Sandri, M.T.3
-
15
-
-
33748463225
-
Prolonged clinical benefit with metronomic chemotherapy in patients with metastatic breast cancer
-
L. Orlando, A. Cardillo, and A. Rocca Prolonged clinical benefit with metronomic chemotherapy in patients with metastatic breast cancer Anticancer Drugs 17 2006 961
-
(2006)
Anticancer Drugs
, vol.17
, pp. 961
-
-
Orlando, L.1
Cardillo, A.2
Rocca, A.3
-
16
-
-
0031027531
-
Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R))
-
R.J. Kowalski, P. Giannakakou, and E. Hamel Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R)) J Biol Chem 272 1997 2534
-
(1997)
J Biol Chem
, vol.272
, pp. 2534
-
-
Kowalski, R.J.1
Giannakakou, P.2
Hamel, E.3
-
17
-
-
0141507953
-
Suppression of microtubule dynamics by epothilone B is associated with mitotic arrest
-
K. Kamath, and M.A. Jordan Suppression of microtubule dynamics by epothilone B is associated with mitotic arrest Cancer Res 63 2003 6026
-
(2003)
Cancer Res
, vol.63
, pp. 6026
-
-
Kamath, K.1
Jordan, M.A.2
-
18
-
-
35848969354
-
Epothilones induce human colon cancer SW620 cell apoptosis via the tubulin polymerization independent activation of the nuclear factor-κB/IκB kinase signal pathway
-
S.H. Lee, S.M. Son, and D.J. Son Epothilones induce human colon cancer SW620 cell apoptosis via the tubulin polymerization independent activation of the nuclear factor-κB/IκB kinase signal pathway Mol Cancer Ther 6 2007 2786
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 2786
-
-
Lee, S.H.1
Son, S.M.2
Son, D.J.3
-
19
-
-
0029049468
-
Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action
-
D.M. Bollag, P.A. McQueney, and J. Zhu Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action Cancer Res 55 1995 2325
-
(1995)
Cancer Res
, vol.55
, pp. 2325
-
-
Bollag, D.M.1
McQueney, P.A.2
Zhu, J.3
-
20
-
-
0032416734
-
Desoxyepothilone B is curative against human tumor xenografts that are refractory to paclitaxel
-
T.C. Chou, X.G. Zhang, and C.R. Harris Desoxyepothilone B is curative against human tumor xenografts that are refractory to paclitaxel Proc Natl Acad Sci U S A 95 1998 15798
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 15798
-
-
Chou, T.C.1
Zhang, X.G.2
Harris, C.R.3
-
21
-
-
33644831567
-
Phase i dose-finding study of weekly single-agent patupilone in patients with advanced solid tumors
-
E.H. Rubin, J. Rothermel, and F. Tesfaye Phase I dose-finding study of weekly single-agent patupilone in patients with advanced solid tumors J Clin Oncol 23 2005 9120
-
(2005)
J Clin Oncol
, vol.23
, pp. 9120
-
-
Rubin, E.H.1
Rothermel, J.2
Tesfaye, F.3
-
22
-
-
33749565180
-
Microtubule-targeting agents inhibit angiogenesis at sub-toxic concentrations, a process associated with inhibition of Rac1 and Cdc42 activity and changes in the endothelial cytoskeleton
-
M.N. Bijman, G.P. van Nieuw Amerongen, and N. Laurens Microtubule-targeting agents inhibit angiogenesis at sub-toxic concentrations, a process associated with inhibition of Rac1 and Cdc42 activity and changes in the endothelial cytoskeleton Mol Cancer Ther 5 2006 2348
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2348
-
-
Bijman, M.N.1
Van Nieuw Amerongen, G.P.2
Laurens, N.3
-
23
-
-
85047690366
-
Development of a novel in vitro human tissue-based angiogenesis assay to evaluate the effect of anti-angiogenic drugs
-
E.A. Woltering, J.M. Lewis, and P.J. Maxwell Development of a novel in vitro human tissue-based angiogenesis assay to evaluate the effect of anti-angiogenic drugs Ann Surg 237 2003 790
-
(2003)
Ann Surg
, vol.237
, pp. 790
-
-
Woltering, E.A.1
Lewis, J.M.2
Maxwell, P.J.3
-
24
-
-
0030773083
-
Breast cancer increases initiation of angiogenesis without accelerating neovessel growth rate
-
J.C. Watson, J.G. Redmann, and M.O. Meyers Breast cancer increases initiation of angiogenesis without accelerating neovessel growth rate Surgery 122 1997 508
-
(1997)
Surgery
, vol.122
, pp. 508
-
-
Watson, J.C.1
Redmann, J.G.2
Meyers, M.O.3
-
25
-
-
34547486126
-
Phase II study of metronomic chemotherapy for recurrent malignant gliomas in adults
-
S. Kesari, D. Schiff, and L. Doherty Phase II study of metronomic chemotherapy for recurrent malignant gliomas in adults Neuro Oncol 9 2007 354
-
(2007)
Neuro Oncol
, vol.9
, pp. 354
-
-
Kesari, S.1
Schiff, D.2
Doherty, L.3
-
26
-
-
0036532055
-
Combined anti-fetal liver kinase 1 monoclonal antibody and continuous low-dose doxorubicin inhibits angiogenesis and growth of human soft tissue sarcoma xenografts by induction of endothelial cell apoptosis
-
L. Zhang, D. Yu, and D.J. Hicklin Combined anti-fetal liver kinase 1 monoclonal antibody and continuous low-dose doxorubicin inhibits angiogenesis and growth of human soft tissue sarcoma xenografts by induction of endothelial cell apoptosis Cancer Res 62 2002 2034
-
(2002)
Cancer Res
, vol.62
, pp. 2034
-
-
Zhang, L.1
Yu, D.2
Hicklin, D.J.3
-
27
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
H. Hurwitz, L. Fehrenbacher, and W. Novotny Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer N Engl J Med 350 2004 2335
-
(2004)
N Engl J Med
, vol.350
, pp. 2335
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
-
28
-
-
0242331613
-
Thrombospondin 1, a mediator of the anti-angiogenic effects of low-dose metronomic chemotherapy
-
G. Bocci, G. Francia, and S. Man Thrombospondin 1, a mediator of the anti-angiogenic effects of low-dose metronomic chemotherapy Proc Natl Acad Sci USA 100 2003 12917
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 12917
-
-
Bocci, G.1
Francia, G.2
Man, S.3
-
29
-
-
0037458325
-
Minimizing long-term tumor burden: The logic for metronomic chemotherapeutic dosing and its anti-angiogenic basis
-
P. Hahnfeldt, J. Folkman, and L. Hlatky Minimizing long-term tumor burden: The logic for metronomic chemotherapeutic dosing and its anti-angiogenic basis J Theor Biol 220 2003 545
-
(2003)
J Theor Biol
, vol.220
, pp. 545
-
-
Hahnfeldt, P.1
Folkman, J.2
Hlatky, L.3
-
30
-
-
38449120471
-
Novel tubulin-targeting agents: Anticancer activity and pharmacologic profile of epothilones and related analogues
-
P. Fumoleau, B. Coudert, and N. Isambert Novel tubulin-targeting agents: Anticancer activity and pharmacologic profile of epothilones and related analogues Ann Oncol 18 Suppl 5 2007 v9
-
(2007)
Ann Oncol
, vol.18
, Issue.SUPPL. 5
, pp. 9
-
-
Fumoleau, P.1
Coudert, B.2
Isambert, N.3
-
31
-
-
38449091336
-
Potential clinical applications of epothilones: A review of phase II studies
-
J.M. Larkin, and S.B. Kaye Potential clinical applications of epothilones: A review of phase II studies Ann Oncol 18 Suppl 5 2007 v28
-
(2007)
Ann Oncol
, vol.18
, Issue.SUPPL. 5
, pp. 28
-
-
Larkin, J.M.1
Kaye, S.B.2
-
32
-
-
34548385800
-
Phase i clinical study of the novel epothilone B analogue BMS-310705 given on a weekly schedule
-
C. Sessa, A. Perotti, and A. Llado Phase I clinical study of the novel epothilone B analogue BMS-310705 given on a weekly schedule Ann Oncol 18 2007 1548
-
(2007)
Ann Oncol
, vol.18
, pp. 1548
-
-
Sessa, C.1
Perotti, A.2
Llado, A.3
|