Variation in the CYP19A1 gene and risk of colon and rectal cancer

Cancer Causes and Control

Volumn 22, Issue 7, 2011, Pages 955-963

  Slattery, Martha L ^a   Lundgreen, Abbie ^a   Herrick, Jennifer S ^a   Kadlubar, Susan ^b   Caan, Bette J ^c   Potter, John D ^d   Wolff, Roger K ^a  

^a UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

^b UNIVERSITY OF ARKANSAS AT LITTLE ROCK   (United States)

^c DIVISION OF RESEARCH   (United States)

^d USA   (United States)

Author keywords

Aspirin; BMI; CIMP+; Colon cancer; CYP19A1; KRAS2; MSI; NF B1; Rectal cancer

Indexed keywords

ANDROGEN; AROMATASE; ESTROGEN; TUMOR MARKER;

ADULT; AGED; AR ONCOGENE; ARTICLE; CANCER RISK; CARCINOGENESIS; CASE CONTROL STUDY; COLON CANCER; COLON CARCINOGENESIS; CONTROLLED STUDY; CYP19A1 ONCOGENE; ESR1 ONCOGENE; ESR2 ONCOGENE; FEMALE; GENE INTERACTION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; NFKB1 ONCOGENE; ONCOGENE; ONCOGENE K RAS; ONCOGENE K RAS2; POPULATION RESEARCH; PRIORITY JOURNAL; RECTUM CANCER; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; AGED, 80 AND OVER; AROMATASE; CARCINOMA; CASE-CONTROL STUDIES; COLONIC NEOPLASMS; ESTROGENS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOTYPE; HUMANS; INFLAMMATION; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RECTAL NEOPLASMS; RISK FACTORS;

EID: 79960213234     PISSN: 09575243     EISSN: 15737225     Source Type: Journal    
DOI: 10.1007/s10552-011-9768-x     Document Type: Article

References (46)

1. HD Nelson LL Humphrey P Nygren, et al. 2002 Postmenopausal hormone replacement therapy: scientific review JAMA 288 872 881 12186605 10.1001/jama.288.7.872 1:CAS:528:DC%2BD38Xmt1yitL8%3D
2. K Nanda LA Bastian V Hasselblad DL Simel 1999 Hormone replacement therapy and the risk of colorectal cancer: a meta-analysis Obstet Gynecol 93 880 888 10912438 10.1016/S0029-7844(98)00424-4 1:STN:280:DC%2BD3czovVyktw%3D%3D (Pubitemid 29197937)
3. AJ McMichael JD Potter 1980 Reproduction, endogenous and exogenous sex hormones, and colon cancer: a review and hypothesis J Natl Cancer Inst 65 1201 1207 7001123 1:STN:280:DyaL3M%2FltVejsQ%3D%3D (Pubitemid 11196006)
4. RT Chlebowski J Wactawski-Wende C Ritenbaugh, et al. 2004 Estrogen plus progestin and colorectal cancer in postmenopausal women N Engl J Med 350 991 1004 14999111 10.1056/NEJMoa032071 1:CAS:528:DC%2BD2cXhvFGjs7g%3D (Pubitemid 38269276)
5. ML Slattery R Ballard-Barbash S Edwards, et al. 2003 Body mass index and colon cancer: an evaluation of the modifying effects of estrogen (United States) Cancer Causes Control 14 75 84 12708728 10.1023/A:1022545017867 1:STN:280:DC%2BD3s7ovFCgtg%3D%3D (Pubitemid 36403272)
6. ML Slattery JD Potter K Curtin, et al. 2001 Estrogens reduce and withdrawal of estrogens increase risk of microsatellite instability-positive colon cancer Cancer Res 61 126 130 11196149 1:CAS:528:DC%2BD3MXlsl2ltg%3D%3D (Pubitemid 32095709)
7. ML Slattery K Anderson W Samowitz, et al. 1999 Hormone replacement therapy and improved survival among postmenopausal women diagnosed with colon cancer (USA) Cancer Causes Control 10 467 473 10530618 10.1023/A:1008974215622 1:STN:280:DyaK1MvlvVajsw%3D%3D (Pubitemid 29454325)
8. DL Segev TU Ha TT Tran, et al. 2000 Mullerian inhibiting substance inhibits breast cancer cell growth through an NFkappa B-mediated pathway J Biol Chem 275 28371 28379 10874041 10.1074/jbc.M004554200 1:CAS:528: DC%2BD3cXms1Crur4%3D
9. DH Fagan D Yee 2008 Crosstalk between IGF1R and estrogen receptor signaling in breast cancer J Mammary Gland Biol Neoplasia 13 423 429 19003523 10.1007/s10911-008-9098-0
10. D Catalano GM Trovato D Spadaro, et al. 2008 Insulin resistance in postmenopausal women: concurrent effects of hormone replacement therapy and coffee Climacteric 11 373 382 18781481 10.1080/13697130802348728 1:CAS:528:DC%2BD1cXhtFaisrjJ
11. M Marino P Galluzzo S Leone, et al. 2006 Nitric oxide impairs the 17beta-estradiol-induced apoptosis in human colon adenocarcinoma cells Endocr Relat Cancer 13 559 569 16728582 10.1677/erc.1.01106 1:CAS:528: DC%2BD28XntF2mtb0%3D (Pubitemid 43890873)
12. ML Slattery MA Murtaugh C Quesenberry, et al. 2007 Changing population characteristics, effect-measure modification, cancer risk factor identification Epidemiol Perspect Innov 4 10 17908309 10.1186/1742-5573-4-10 (Pubitemid 350198386)
13. M Cutolo A Sulli S Capellino, et al. 2004 Sex hormones influence on the immune system: basic and clinical aspects in autoimmunity Lupus 13 635 638 15485092 10.1191/0961203304lu1094oa 1:CAS:528:DC%2BD2cXptlKks78%3D (Pubitemid 39279773)
14. R Deshpande H Khalili RG Pergolizzi, et al. 1997 Estradiol down-regulates LPS-induced cytokine production and NFkB activation in murine macrophages Am J Reprod Immunol 38 46 54 9266010 1:STN:280:DyaK2svhtV2lsw%3D%3D (Pubitemid 27308153)
15. NJ Camp ML Slattery 2002 Classification tree analysis: a statistical tool to investigate risk factor interactions with an example for colon cancer (United States) Cancer Causes Control 13 813 823 12462546 10.1023/A: 1020611416907 (Pubitemid 35305200)
16. LJ Marnett 1992 Aspirin and the potential role of prostaglandins in colon cancer Cancer Res 52 5575 5589 1394181 1:CAS:528:DyaK38XmsV2htLo%3D
17. ML Slattery FA Fitzpatrick 2009 Convergence of hormones, inflammation, and energy-related factors: a novel pathway of cancer etiology Cancer Prev Res (Phila Pa) 2 922 930 10.1158/1940-6207.CAPR-08-0191 1:CAS:528: DC%2BC3cXptVyrsb0%3D
18. ML Slattery C Sweeney M Murtaugh, et al. 2005 Associations between ERalpha, ERbeta, and AR genotypes and colon and rectal cancer Cancer Epidemiol Biomarkers Prev 14 2936 2942 16365013 10.1158/1055-9965.EPI-05-0514 1:CAS:528:DC%2BD2MXhtlahs7vN (Pubitemid 43068828)
19. J Lin RY Zee KY Liu, et al. 2010 Genetic variation in sex-steroid receptors and synthesizing enzymes and colorectal cancer risk in women Cancer Causes Control 21 897 908 20148360 10.1007/s10552-010-9518-5
20. JC Huber C Schneeberger CB Tempfer 2002 Genetic modelling of the estrogen metabolism as a risk factor of hormone-dependent disorders Maturitas 42 1 12 12020974 10.1016/S0378-5122(02)00021-X 1:CAS:528:DC%2BD38XjvVWjsb0%3D (Pubitemid 34521716)
21. ML Slattery JD Potter DM Duncan TD Berry 1997 Dietary fats and colon cancer: assessment of risk associated with specific fatty acids Int J Cancer 73 670 677 9398044 10.1002/(SICI)1097-0215(19971127)73:5<670::AID-IJC10>3.0. CO;2-A 1:CAS:528:DyaK2sXns1Kmtrk%3D (Pubitemid 127483062)
22. ML Slattery BJ Caan J Benson M Murtaugh 2003 Energy balance and rectal cancer: an evaluation of energy intake, energy expenditure, and body mass index Nutr Cancer 46 166 171 14690792 10.1207/S15327914NC4602-09 (Pubitemid 37504976)
23. ML Slattery J Potter B Caan, et al. 1997 Energy balance and colon cancer-beyond physical activity Cancer Res 57 75 80 8988044 1:CAS:528: DyaK2sXjvFOisQ%3D%3D (Pubitemid 27020333)
24. ML Slattery S Edwards K Curtin, et al. 2003 Physical activity and colorectal cancer Am J Epidemiol 158 214 224 12882943 10.1093/aje/kwg134 1:STN:280:DC%2BD3szltVeisA%3D%3D (Pubitemid 36944414)
25. S Edwards ML Slattery M Mori, et al. 1994 Objective system for interviewer performance evaluation for use in epidemiologic studies Am J Epidemiol 140 1020 1028 7985650 1:STN:280:DyaK2M%2Fns12msA%3D%3D (Pubitemid 24373007)
26. WS Samowitz K Curtin KN Ma, et al. 2002 Prognostic significance of p53 mutations in colon cancer at the population level Int J Cancer 99 597 602 11992552 10.1002/ijc.10405 1:CAS:528:DC%2BD38XjsFansb8%3D (Pubitemid 34461615)
27. ML Slattery K Curtin K Anderson, et al. 2000 Associations between cigarette smoking, lifestyle factors, and microsatellite instability in colon tumors J Natl Cancer Inst 92 1831 1836 11078760 10.1093/jnci/92.22.1831 1:STN:280:DC%2BD3M3jt1eisg%3D%3D
28. WS Samowitz K Curtin D Schaffer, et al. 2000 Relationship of Ki-ras mutations in colon cancers to tumor location, stage, and survival: a population-based study Cancer Epidemiol Biomarkers Prev 9 1193 1197 11097226 1:CAS:528:DC%2BD3cXos12isb4%3D
29. ML Slattery K Curtin C Sweeney, et al. 2007 Diet and lifestyle factor associations with CpG island methylator phenotype and BRAF mutations in colon cancer Int J Cancer 120 656 663 17096326 10.1002/ijc.22342 1:CAS:528: DC%2BD28XhtlGqs77P (Pubitemid 44969038)
30. KN Conneely M Boehnke 2007 So many correlated tests, so little time! Rapid adjustment of p values for multiple correlated tests Am J Hum Genet 81 1158 1168 17966093 10.1086/522036 1:CAS:528:DC%2BD2sXhtl2ju77N (Pubitemid 350211447)
31. ML Slattery K Curtin RK Wolff, et al. 2009 A comparison of colon and rectal somatic DNA alterations Dis Colon Rectum 52 1304 1311 19571709 10.1007/DCR.0b013e3181a0e5df
32. Y Benjamini YaH 1995 Controlling the false discovery rate: a practical and powerful approach to multiple testing J Roy Stat Soc 57 289 300
33. K Kawakami A Ruszkiewicz G Bennett, et al. 2006 DNA hypermethylation in the normal colonic mucosa of patients with colorectal cancer Br J Cancer 94 593 598 16421593 10.1038/sj.bjc.6602940 1:CAS:528:DC%2BD28Xhs1ersrw%3D (Pubitemid 43289765)
34. CA Haiman L Dossus VW Setiawan, et al. 2007 Genetic variation at the CYP19A1 locus predicts circulating estrogen levels but not breast cancer risk in postmenopausal women Cancer Res 67 1893 1897 17325027 10.1158/0008-5472.CAN-06- 4123 1:CAS:528:DC%2BD2sXit12qtbg%3D (Pubitemid 46424203)
35. IM Dick A Devine RL Prince 2005 Association of an aromatase TTTA repeat polymorphism with circulating estrogen, bone structure, and biochemistry in older women Am J Physiol Endocrinol Metab 288 E989 E995 15613678 10.1152/ajpendo.00550.2004 1:CAS:528:DC%2BD2MXktlSnsrg%3D (Pubitemid 40547894)
36. AM Dunning M Dowsett CS Healey, et al. 2004 Polymorphisms associated with circulating sex hormone levels in postmenopausal women J Natl Cancer Inst 96 936 945 15199113 10.1093/jnci/djh167 1:CAS:528:DC%2BD2cXltVWmtb8%3D (Pubitemid 38868140)
37. T Salmen AM Heikkinen A Mahonen, et al. 2003 Relation of aromatase gene polymorphism and hormone replacement therapy to serum estradiol levels, bone mineral density, and fracture risk in early postmenopausal women Ann Med 35 282 288 12846271 10.1080/07853890310006370 (Pubitemid 36791696)
38. RC Travis F Schumacher JN Hirschhorn, et al. 2009 CYP19A1 genetic variation in relation to prostate cancer risk and circulating sex hormone concentrations in men from the Breast and Prostate Cancer Cohort Consortium Cancer Epidemiol Biomarkers Prev 18 2734 2744 19789370 10.1158/1055-9965.EPI-09- 0496 1:CAS:528:DC%2BD1MXht1OiurnK
39. VW Setiawan JA Doherty XO Shu, et al. 2009 Two estrogen-related variants in CYP19A1 and endometrial cancer risk: a pooled analysis in the Epidemiology of Endometrial Cancer Consortium Cancer Epidemiol Biomarkers Prev 18 242 247 19124504 10.1158/1055-9965.EPI-08-0689 1:CAS:528:DC%2BD1MXhvFeqsg%3D%3D
40. Q Cai N Kataoka C Li, et al. 2008 Haplotype analyses of CYP19A1 gene variants and breast cancer risk: results from the Shanghai Breast Cancer Study Cancer Epidemiol Biomarkers Prev 17 27 32 18199708 10.1158/1055-9965.EPI-07-0688 1:CAS:528:DC%2BD1cXmt12gsA%3D%3D (Pubitemid 351196270)
41. MH Tao Q Cai ZF Zhang, et al. 2007 Polymorphisms in the CYP19A1 (aromatase) gene and endometrial cancer risk in Chinese women Cancer Epidemiol Biomarkers Prev 16 943 949 17507620 10.1158/1055-9965.EPI-06-1012 1:CAS:528:DC%2BD2sXltlWgt7s%3D (Pubitemid 46910096)
42. L Wang KA Ellsworth I Moon, et al. 2010 Functional genetic polymorphisms in the aromatase gene CYP19 vary the response of breast cancer patients to neoadjuvant therapy with aromatase inhibitors Cancer Res 70 319 328 20048079 10.1158/0008-5472.CAN-09-3224 1:CAS:528:DC%2BC3cXltVSn
43. WH Xu Q Dai YB Xiang, et al. 2007 Interaction of soy food and tea consumption with CYP19A1 genetic polymorphisms in the development of endometrial cancer Am J Epidemiol 166 1420 1430 17827443 10.1093/aje/kwm242 (Pubitemid 350209050)
44. Y Guo DH Xiong TL Yang, et al. 2006 Polymorphisms of estrogen- biosynthesis genes CYP17 and CYP19 may influence age at menarche: a genetic association study in Caucasian females Hum Mol Genet 15 2401 2408 16782804 10.1093/hmg/ddl155 1:CAS:528:DC%2BD28Xotlais7w%3D (Pubitemid 44288694)
45. RB Riggins AH Bouton MC Liu R Clarke 2005 Antiestrogens, aromatase inhibitors, and apoptosis in breast cancer Vitam Horm 71 201 237 16112269 10.1016/S0083-6729(05)71007-4 1:CAS:528:DC%2BD28XotlSiur4%3D (Pubitemid 43631307)
46. R Sato T Suzuki Y Katayose, et al. 2009 Steroid sulfatase and estrogen sulfotransferase in colon carcinoma: regulators of intratumoral estrogen concentrations and potent prognostic factors Cancer Res 69 914 922 19141651 10.1158/0008-5472.CAN-08-0906 1:CAS:528:DC%2BD1MXhtFOktb4%3D