Micronization of dihydroartemisinin by rapid expansion of supercritical solutions

Drug Development and Industrial Pharmacy

Volumn 34, Issue 6, 2008, Pages 609-617

  Chingunpitak, Jiraporn ^a   Puttipipatkhachorn, Satit ^a   Tozuka, Yuichi ^b   Moribe, Kunikazu ^c   Yamamoto, Keiji ^c  

^a MAHIDOL UNIVERSITY   (Thailand)

^b GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^c CHIBA UNIVERSITY   (Japan)

Author keywords

Dihydroartemisinin; Micronization; Rapid expansion of supercritical solutions; RESS; Supercritical fluid

Indexed keywords

CARBON DIOXIDE; DIHYDROARTEMISININ;

ARTICLE; DRUG MANUFACTURE; DRUG SOLUBILITY; DRUG SYNTHESIS; MICRONIZATION; MORPHOLOGY; PARTICLE SIZE; PHYSICAL CHEMISTRY; RAPID EXPANSION OF SUPERCRITICAL SOLUTION; SUPERCRITICAL FLUID; SUPERCRITICAL FLUID EXTRACTION; X RAY DIFFRACTION;

ANTIMALARIALS; ARTEMISININS; CALORIMETRY, DIFFERENTIAL SCANNING; CARBON DIOXIDE; DRUG COMPOUNDING; MICROSCOPY, ELECTRON, SCANNING; PARTICLE SIZE; SOLUTIONS; TEMPERATURE; X-RAY DIFFRACTION;

EID: 45849151126     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.1080/03639040701833682     Document Type: Article

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