메뉴 건너뛰기




Volumn 2, Issue MAR, 2011, Pages

New concepts in immunity to Neisseria gonorrhoeae: Innate responses and suppression of adaptive immunity favor the pathogen, not the host

Author keywords

Adaptive immunity; IL 17; Immunosuppression; Innate immunity; TGF ; Th17

Indexed keywords


EID: 79960182157     PISSN: None     EISSN: 1664302X     Source Type: Journal    
DOI: 10.3389/fmicb.2011.00052     Document Type: Article
Times cited : (67)

References (69)
  • 1
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the gen-eration of pathogenic effector TH17 and regulatory T cells
    • Bettelli, E., Carrier, Y., Gao, W., Korn, T., Strom, T. B., Oukka, M., Weiner, H. L., and Kuchroo, V. K. (2006). Reciprocal developmental pathways for the gen-eration of pathogenic effector TH17 and regulatory T cells. Nature 441, 235-238
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3    Korn, T.4    Strom, T.B.5    Oukka, M.6    Weiner, H.L.7    Kuchroo, V.K.8
  • 3
    • 0036009113 scopus 로고    scopus 로고
    • Neisserial binding to CEACAM1 arrests the activation and proliferation of CD4+ T lymphocytes
    • Boulton, I. C., and Gray-Owen, S. D. (2002). Neisserial binding to CEACAM1 arrests the activation and proliferation of CD4+ T lymphocytes. Nat. Immunol. 3, 229-236
    • (2002) Nat. Immunol. , vol.3 , pp. 229-236
    • Boulton, I.C.1    Gray-Owen, S.D.2
  • 5
    • 0018726974 scopus 로고
    • Demonstration of intracellular growth of gonococci in human phagocytes using spectinomycin to kill extracellular organisms
    • Casey, S. G., Veale, D. R., and Smith, H. (1979). Demonstration of intracellular growth of gonococci in human phagocytes using spectinomycin to kill extracellular organisms. J. Gen. Microbiol. 113, 395-398
    • (1979) J. Gen. Microbiol. , vol.113 , pp. 395-398
    • Casey, S.G.1    Veale, D.R.2    Smith, H.3
  • 7
    • 46049091614 scopus 로고    scopus 로고
    • Identification and characterization of gonococcal iron transport systems as potential vaccine antigens
    • Cornelissen, C. N. (2008). Identification and characterization of gonococcal iron transport systems as potential vaccine antigens. Future Microbiol. 3, 287-298
    • (2008) Future Microbiol , vol.3 , pp. 287-298
    • Cornelissen, C.N.1
  • 8
    • 66749099428 scopus 로고    scopus 로고
    • Resistance of Neisseria gonorrhoeae to non-oxidative killing by adherent human polymorphonuclear leucocytes
    • Criss, A. K., Katz, B. Z., and Seifert, H. S. (2009). Resistance of Neisseria gonorrhoeae to non-oxidative killing by adherent human polymorphonuclear leucocytes. Cell. Microbiol. 11, 1074-1087
    • (2009) Cell. Microbiol. , vol.11 , pp. 1074-1087
    • Criss, A.K.1    Katz, B.Z.2    Seifert, H.S.3
  • 9
    • 54049127365 scopus 로고    scopus 로고
    • Neisseria gonorrhoeae suppresses the oxidative burst of human polymor-phonuclear leukocytes
    • Criss, A. K., and Seifert, H. S. (2008). Neisseria gonorrhoeae suppresses the oxidative burst of human polymor-phonuclear leukocytes. Cell. Microbiol. 10, 2257-2270
    • (2008) Cell. Microbiol. , vol.10 , pp. 2257-2270
    • Criss, A.K.1    Seifert, H.S.2
  • 10
    • 58149296036 scopus 로고    scopus 로고
    • Interleukin-17 in host defence against bacterial, mycobacterial and fungal pathogens
    • Curtis, M. M., and Way, S. S. (2009). Interleukin-17 in host defence against bacterial, mycobacterial and fungal pathogens. Immunology 126, 177-185
    • (2009) Immunology , vol.126 , pp. 177-185
    • Curtis, M.M.1    Way, S.S.2
  • 11
    • 0032408860 scopus 로고    scopus 로고
    • The role of neisserial Opa proteins in interactions with host cells
    • Dehio, C., Gray-Owen, S. D., and Meyer, T. F. (1998). The role of neisserial Opa proteins in interactions with host cells. Trends Microbiol. 6, 489-495
    • (1998) Trends Microbiol , vol.6 , pp. 489-495
    • Dehio, C.1    Gray-Owen, S.D.2    Meyer, T.F.3
  • 12
    • 77951483708 scopus 로고    scopus 로고
    • Critical role of [17Th] responses in a murine model of Neisseria gonorrhoeae genital infection
    • Feinen, B., Jerse, A. E., Gaffen, S. L., and Russell, M. W. (2010). Critical role of [17Th] responses in a murine model of Neisseria gonorrhoeae genital infection. Mucosal Immunol. 3, 312-321
    • (2010) Mucosal Immunol , vol.3 , pp. 312-321
    • Feinen, B.1    Jerse, A.E.2    Gaffen, S.L.3    Russell, M.W.4
  • 13
    • 0034874761 scopus 로고    scopus 로고
    • Distinct proinflammatory host responses to Neisseria gonorrhoeae infection in immortalized human cervical and vaginal epithelial cells
    • Fichorova, R. N., Desai, P. J., Gibson, F. C., and Genco, C. A. (2001). Distinct proinflammatory host responses to Neisseria gonorrhoeae infection in immortalized human cervical and vaginal epithelial cells. Infect. Immun. 69, 5840-5848
    • (2001) Infect. Immun. , vol.69 , pp. 5840-5848
    • Fichorova, R.N.1    Desai, P.J.2    Gibson, F.C.3    Genco, C.A.4
  • 17
    • 27544490377 scopus 로고    scopus 로고
    • Interleukin 17-producing CD4+ effec-tor T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
    • Harrington, L. E., Hatton, R. D., Mangan, P. R., Turner, H., Murphy, T. L., Murphy, K. M., and Weaver, C. T. (2005). Interleukin 17-producing CD4+ effec-tor T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat. Immunol. 6, 1123-1132
    • (2005) Nat. Immunol. , vol.6 , pp. 1123-1132
    • Harrington, L.E.1    Hatton, R.D.2    Mangan, P.R.3    Turner, H.4    Murphy, T.L.5    Murphy, K.M.6    Weaver, C.T.7
  • 18
    • 0024712514 scopus 로고
    • The potential protective effect of immunization with outer- membrane protein I from Neisseria gonorrhoeae
    • Heckels, J. E., Fletcher, J. N., and Virji, M. (1989). The potential protective effect of immunization with outer- membrane protein I from Neisseria gonorrhoeae. J. Gen. Microbiol. 135, 2269-2276
    • (1989) J. Gen. Microbiol. , vol.135 , pp. 2269-2276
    • Heckels, J.E.1    Fletcher, J.N.2    Virji, M.3
  • 19
    • 0032769613 scopus 로고    scopus 로고
    • Limited local and systemic antibody responses to Neisseria gonorrhoeae during uncomplicated genital infections
    • Hedges, S. R., Mayo, M. S., Mestecky, J., Hook, E. W., and Russell, M. W. (1999). Limited local and systemic antibody responses to Neisseria gonorrhoeae during uncomplicated genital infections. Infect. Immun. 67, 3937-3946
    • (1999) Infect. Immun. , vol.67 , pp. 3937-3946
    • Hedges, S.R.1    Mayo, M.S.2    Mestecky, J.3    Hook, E.W.4    Russell, M.W.5
  • 20
    • 0031656028 scopus 로고    scopus 로고
    • Cytokine and antibody responses in women infected with Neisseria gonor-rhoeae: effects of concomitant infections
    • Hedges, S. R., Sibley, D., Mayo, M. S., Hook, E. W., and Russell, M. W. (1998). Cytokine and antibody responses in women infected with Neisseria gonor-rhoeae: effects of concomitant infections. J. Infect. Dis. 178, 742-751
    • (1998) J. Infect. Dis. , vol.178 , pp. 742-751
    • Hedges, S.R.1    Sibley, D.2    Mayo, M.S.3    Hook, E.W.4    Russell, M.W.5
  • 21
    • 33751579426 scopus 로고    scopus 로고
    • TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertus-sis: role of IL-17-producing T cells
    • Higgins, S. C., Jarnicki, A. G., Lavelle, E. C., and Mills, K. H. G. (2006). TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertus-sis: role of IL-17-producing T cells. J. Immunol. 177, 7980-7989
    • (2006) J. Immunol. , vol.177 , pp. 7980-7989
    • Higgins, S.C.1    Jarnicki, A.G.2    Lavelle, E.C.3    Mills, K.H.G.4
  • 22
    • 64349102519 scopus 로고    scopus 로고
    • Pilin gene variation in Neisseria gonorrhoeae: reassessing the old paradigms
    • Hill, S. A., and Davies, J. K. (2009). Pilin gene variation in Neisseria gonorrhoeae: reassessing the old paradigms. FEMS Microbiol. Rev. 33, 521-530
    • (2009) FEMS Microbiol. Rev. , vol.33 , pp. 521-530
    • Hill, S.A.1    Davies, J.K.2
  • 24
    • 0032707631 scopus 로고    scopus 로고
    • Experimental gonococcal genital tract infection and opacity protein expression in estradiol-treated mice
    • Jerse, A. E. (1999). Experimental gonococcal genital tract infection and opacity protein expression in estradiol-treated mice. Infect. Immun. 67, 5699-5708
    • (1999) Infect. Immun. , vol.67 , pp. 5699-5708
    • Jerse, A.E.1
  • 25
    • 0028014274 scopus 로고
    • Multiple gonococcal opacity proteins are expressed during experimental urethral infection in the male
    • Jerse, A. E., Cohen, M. S., Drown, P. M., Whicker, L. G., Isbey, S. F., Seifert, S., and Cannon, J. G. (1994). Multiple gonococcal opacity proteins are expressed during experimental urethral infection in the male. J. Exp. Med. 179, 911-920
    • (1994) J. Exp. Med. , vol.179 , pp. 911-920
    • Jerse, A.E.1    Cohen, M.S.2    Drown, P.M.3    Whicker, L.G.4    Isbey, S.F.5    Seifert, S.6    Cannon, J.G.7
  • 26
    • 0031156034 scopus 로고    scopus 로고
    • Adhesion and invasion by the pathogenic Neisseria
    • Jerse, A. E., and Rest, R. F. (1997). Adhesion and invasion by the pathogenic Neisseria. Trends Microbiol. 5, 217-221
    • (1997) Trends Microbiol , vol.5 , pp. 217-221
    • Jerse, A.E.1    Rest, R.F.2
  • 27
    • 69249145293 scopus 로고    scopus 로고
    • Th17 cells at the crossroads of innate and adaptive immunity against infectious diseases at the mucosa
    • Khader, S. A., Gaffen, S. L., and Kolls, J. K. (2009). Th17 cells at the crossroads of innate and adaptive immunity against infectious diseases at the mucosa. Mucosal Immunol. 2, 403-411
    • (2009) Mucosal Immunol , vol.2 , pp. 403-411
    • Khader, S.A.1    Gaffen, S.L.2    Kolls, J.K.3
  • 28
    • 5644277476 scopus 로고    scopus 로고
    • Interleukin-17 family members and inflammation
    • Kolls, J. K., and Linden, A. (2004). Interleukin-17 family members and inflammation. Immunity 21, 467-476
    • (2004) Immunity , vol.21 , pp. 467-476
    • Kolls, J.K.1    Linden, A.2
  • 29
    • 54949142477 scopus 로고    scopus 로고
    • Cytokine-mediated regulation of antimicrobial proteins
    • Kolls, J. K., McCray, P. B., and Chan, Y. R. (2008). Cytokine-mediated regulation of antimicrobial proteins. Nat. Rev. Immunol. 8, 829-835
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 829-835
    • Kolls, J.K.1    McCray, P.B.2    Chan, Y.R.3
  • 30
    • 77952138257 scopus 로고    scopus 로고
    • Interactions of Neisseria with complement
    • eds C. A. Genco and L. Wetzler (Norfolk: Caister Academic Press)
    • Lewis, L. A., Burrowes, E., Rice, P. A., and Ram, S. (2010). "Interactions of Neisseria with complement," in Neisseria: Molecular Mechanisms of Pathogenesis, eds. C. A. Genco and L. Wetzler (Norfolk: Caister Academic Press), 123-144
    • (2010) in Neisseria: Molecular Mechanisms of Pathogenesis , pp. 123-144
    • Lewis, L.A.1    Burrowes, E.2    Rice, P.A.3    Ram, S.4
  • 31
    • 55049083674 scopus 로고    scopus 로고
    • Population genomics: diversity and virulence in the Neisseria
    • Maiden, M. C. (2008). Population genomics: diversity and virulence in the Neisseria. Curr. Opin. Microbiol. 11, 467-471
    • (2008) Curr. Opin. Microbiol. , vol.11 , pp. 467-471
    • Maiden, M.C.1
  • 32
    • 0035118341 scopus 로고    scopus 로고
    • Interactions of Neisseria gonorrhoeae with mature human macrophage opacity proteins influence production of proinflammatory cytokines
    • Makepeace, B. L., Watt, P. J., Heckels, J. E., and Christodoulides, M. (2001). Interactions of Neisseria gonorrhoeae with mature human macrophage opacity proteins influence production of proinflammatory cytokines. Infect. Immun. 69, 1909-1913
    • (2001) Infect. Immun. , vol.69 , pp. 1909-1913
    • Makepeace, B.L.1    Watt, P.J.2    Heckels, J.E.3    Christodoulides, M.4
  • 33
    • 0037320106 scopus 로고    scopus 로고
    • The role of porins in neisserial pathogenesis and immunity
    • Massari, P., Ram, S., Macleod, H., and Wetzler, L. M. (2003). The role of porins in neisserial pathogenesis and immunity. Trends Microbiol. 11, 87-93
    • (2003) Trends Microbiol , vol.11 , pp. 87-93
    • Massari, P.1    Ram, S.2    Macleod, H.3    Wetzler, L.M.4
  • 34
    • 1842287946 scopus 로고    scopus 로고
    • Neisseria gonorrhoeae epithelial cell interaction leads to the activation of the transcription factors nuclear factor κB and activator protein 1 and the induction of inflammatory cytokines
    • Naumann, M., Wessler, S., Bartsch, C., Wieland, B., and Meyer, T. F. (1997). Neisseria gonorrhoeae epithelial cell interaction leads to the activation of the transcription factors nuclear factor κB and activator protein 1 and the induction of inflammatory cytokines. J. Exp. Med. 186, 247-258
    • (1997) J. Exp. Med. , vol.186 , pp. 247-258
    • Naumann, M.1    Wessler, S.2    Bartsch, C.3    Wieland, B.4    Meyer, T.F.5
  • 35
    • 0017475977 scopus 로고
    • Recidivism among patients with gonococcal infection presenting to a venereal disease clinic
    • Noble, R. C., Kirk, N. M., Slagel, W. A., Vance, B. J., and Somes, G. W. (1977). Recidivism among patients with gonococcal infection presenting to a venereal disease clinic. Sex. Transm. Dis. 4, 39-43.
    • (1977) Sex. Transm. Dis. , vol.4 , pp. 39-43
    • Noble, R.C.1    Kirk, N.M.2    Slagel, W.A.3    Vance, B.J.4    Somes, G.W.5
  • 36
    • 75949102667 scopus 로고    scopus 로고
    • Interleukin-17 and its target genes: mechanisms of interleukin-17 function in disease
    • Onishi, R. M., and Gaffen, S. L. (2010). Interleukin-17 and its target genes: mechanisms of interleukin-17 function in disease. Immunology 129, 311-321
    • (2010) Immunology , vol.129 , pp. 311-321
    • Onishi, R.M.1    Gaffen, S.L.2
  • 37
    • 50149097975 scopus 로고    scopus 로고
    • IL-22 in mucosal immunity
    • Ouyang, W., and Valdez, P. (2008). IL-22 in mucosal immunity. Mucosal Immunol. 1, 335-338
    • (2008) Mucosal Immunol , vol.1 , pp. 335-338
    • Ouyang, W.1    Valdez, P.2
  • 38
    • 73449137235 scopus 로고    scopus 로고
    • Mouse strain-dependent differences in susceptibility to Neisseria gonorrhoeae infection and induction of innate immune responses
    • Packiam, M., Veit, S. J., Anderson, D. J., Ingalls, R. R., and Jerse, A. E. (2010). Mouse strain-dependent differences in susceptibility to Neisseria gonorrhoeae infection and induction of innate immune responses. Infect. Immun. 78, 433-440
    • (2010) Infect. Immun. , vol.78 , pp. 433-440
    • Packiam, M.1    Veit, S.J.2    Anderson, D.J.3    Ingalls, R.R.4    Jerse, A.E.5
  • 39
    • 21544462006 scopus 로고    scopus 로고
    • Neisseria gonorrhoeae kills carcinoembryonic antigen-related cellular adhesion molecule 1 (CD66a)- expressing human B cells and inhibits antibody production
    • Pantelic, M., Kim, Y.-J., Bolland, S., Chen, I., Shively, J., and Chen, T. (2005). Neisseria gonorrhoeae kills carcinoembryonic antigen-related cellular adhesion molecule 1 (CD66a)- expressing human B cells and inhibits antibody production. Infect. Immun. 73, 4171-4179
    • (2005) Infect. Immun. , vol.73 , pp. 4171-4179
    • Pantelic, M.1    Kim, Y.-J.2    Bolland, S.3    Chen, I.4    Shively, J.5    Chen, T.6
  • 44
    • 0032473556 scopus 로고    scopus 로고
    • A novel sialic acid binding site on factor H mediates serum resistance of sialylated Neisseria gonorrhoeae
    • Ram, S., Sharma, A. K., Simpson, S. D., Gulati, S., McQuillen, D. P., Pangburn, M. K., and Rice, P. A. (1998). A novel sialic acid binding site on factor H mediates serum resistance of sialylated Neisseria gonorrhoeae. J. Exp. Med. 187, 743-752
    • (1998) J. Exp. Med. , vol.187 , pp. 743-752
    • Ram, S.1    Sharma, A.K.2    Simpson, S.D.3    Gulati, S.4    McQuillen, D.P.5    Pangburn, M.K.6    Rice, P.A.7
  • 46
    • 0023018746 scopus 로고
    • Immunoglobulin G antibodies directed against protein III block killing of serum resistant Neisseria gonorrhoeae by immune serum
    • Rice, P. A., Vayo, H. E., Tam, M. R., and Blake, M. S. (1986). Immunoglobulin G antibodies directed against protein III block killing of serum resistant Neisseria gonorrhoeae by immune serum. J. Exp. Med. 164, 1735-1748
    • (1986) J. Exp. Med. , vol.164 , pp. 1735-1748
    • Rice, P.A.1    Vayo, H.E.2    Tam, M.R.3    Blake, M.S.4
  • 48
    • 77952197413 scopus 로고    scopus 로고
    • Tolerance and protection against infection in the genital tract
    • Russell, M. W., and Mestecky, J. (2010). Tolerance and protection against infection in the genital tract. Immunol. Invest. 39, 500-525
    • (2010) Immunol. Invest. , vol.39 , pp. 500-525
    • Russell, M.W.1    Mestecky, J.2
  • 49
    • 0032539553 scopus 로고    scopus 로고
    • Modulation of Neisseria gonorrhoeae susceptibility to vertebrate antibacterial peptides due to a member of the resistance/nodula-tion/division efflux pump family
    • Shafer, W. M., Qu, X., Waring, A. J., and Lehrer, R. I. (1998). Modulation of Neisseria gonorrhoeae susceptibility to vertebrate antibacterial peptides due to a member of the resistance/nodula-tion/division efflux pump family. Proc. Natl. Acad. Sci. U.S.A. 95, 1829-1833.
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 1829-1833
    • Shafer, W.M.1    Qu, X.2    Waring, A.J.3    Lehrer, R.I.4
  • 50
    • 34250198676 scopus 로고    scopus 로고
    • Inhibition of human neu-trophil degranulation by transforming growth factor-β1
    • Shen, L., Smith, J. M., Shen, Z., Eriksson, M., Sentman, C., and Wira, C. R. (2007). Inhibition of human neu-trophil degranulation by transforming growth factor-β1. Clin. Exp. Immunol. 149, 155-161
    • (2007) Clin. Exp. Immunol. , vol.149 , pp. 155-161
    • Shen, L.1    Smith, J.M.2    Shen, Z.3    Eriksson, M.4    Sentman, C.5    Wira, C.R.6
  • 51
    • 33947677787 scopus 로고    scopus 로고
    • Resident Vδ1+ γδ T cells control early infiltration of neutrophils after Escherichia coli infection via IL-17 pro-duction
    • Shibata, K., Yamada, H., Hara, H., Kishihara, K., and Yoshikai, Y. (2007). Resident Vδ1+ γδ T cells control early infiltration of neutrophils after Escherichia coli infection via IL-17 pro-duction. J. Immunol. 178, 4466-4472
    • (2007) J. Immunol. , vol.178 , pp. 4466-4472
    • Shibata, K.1    Yamada, H.2    Hara, H.3    Kishihara, K.4    Yoshikai, Y.5
  • 52
    • 0032849397 scopus 로고    scopus 로고
    • T lymphocyte response to Neisseria gonorrhoeae porin in individuals with mucosal gonococcal infections
    • Simpson, S. D., Ho, Y., Rice, P. A., and Wetzler, L. M. (1999). T lymphocyte response to Neisseria gonorrhoeae porin in individuals with mucosal gonococcal infections. J. Infect. Dis. 180, 762-773
    • (1999) J. Infect. Dis. , vol.180 , pp. 762-773
    • Simpson, S.D.1    Ho, Y.2    Rice, P.A.3    Wetzler, L.M.4
  • 53
    • 0029556313 scopus 로고
    • Sialylation of neisserial lipopolysaccharide: A major influence on pathogenicity
    • Smith, H., Parsons, N. J., and Cole, J. A. (1995). Sialylation of neisserial lipopolysaccharide: A major influence on pathogenicity. Microb. Pathog. 19, 365-377.
    • (1995) Microb. Pathog. , vol.19 , pp. 365-377
    • Smith, H.1    Parsons, N.J.2    Cole, J.A.3
  • 54
    • 52949125249 scopus 로고    scopus 로고
    • Local and humoral immune responses against primary and repeat Neisseria gonorrhoeae genital tract infections of 17β-estradiol-treated mice
    • Song, W., Condron, S., Mocca, B. T., Veit, S. J., Hill, D., Abbas, A., and Jerse, A E. (2008). Local and humoral immune responses against primary and repeat Neisseria gonorrhoeae genital tract infections of 17β-estradiol-treated mice. Vaccine 26, 5741-5751.
    • (2008) Vaccine , vol.26 , pp. 5741-5751
    • Song, W.1    Condron, S.2    Mocca, B.T.3    Veit, S.J.4    Hill, D.5    Abbas, A.6    Jerse, A.E.7
  • 57
    • 63049088278 scopus 로고    scopus 로고
    • Pathogenic neisseriae: surface modulation, pathogenesis and infection control
    • Virji, M. (2009). Pathogenic neisseriae: surface modulation, pathogenesis and infection control. Nat. Rev. Microbiol. 7, 274-286
    • (2009) Nat. Rev. Microbiol. , vol.7 , pp. 274-286
    • Virji, M.1
  • 58
    • 0032752835 scopus 로고    scopus 로고
    • Critical determinants of host receptor targeting by Neisseria menin-gitidis and Neisseria gonorrhoeae: iden-tification of Opa adhesiotopes on the N-domain of CD66 molecules
    • Virji, M., Evans, D., Hadfield, A., Grunert, F., Teixeira, A. M., and Watt, S. M. (1999). Critical determinants of host receptor targeting by Neisseria menin-gitidis and Neisseria gonorrhoeae: iden-tification of Opa adhesiotopes on the N-domain of CD66 molecules. Mol. Microbiol. 34, 538-551
    • (1999) Mol. Microbiol. , vol.34 , pp. 538-551
    • Virji, M.1    Evans, D.2    Hadfield, A.3    Grunert, F.4    Teixeira, A.M.5    Watt, S.M.6
  • 59
    • 0021811575 scopus 로고
    • Role of anti-pilus antibodies in host defense against gonococcal infection studied with monoclonal anti-pilus antibod-ies
    • Virji, M., and Heckels, J. E. (1985). Role of anti-pilus antibodies in host defense against gonococcal infection studied with monoclonal anti-pilus antibod-ies. Infect. Immun. 49, 621-628
    • (1985) Infect. Immun. , vol.49 , pp. 621-628
    • Virji, M.1    Heckels, J.E.2
  • 60
    • 0023814987 scopus 로고
    • Nonbactericidal antibodies against Neisseria gonorrhoeae: evaluation of their blocking effect on bactericidal antibodies directed against outer membrane antigens
    • Virji, M., and Heckels, J. E. (1988). Nonbactericidal antibodies against Neisseria gonorrhoeae: evaluation of their blocking effect on bactericidal antibodies directed against outer membrane antigens. J. Gen. Microbiol. 134, 2703-2711
    • (1988) J. Gen. Microbiol. , vol.134 , pp. 2703-2711
    • Virji, M.1    Heckels, J.E.2
  • 61
    • 33847206969 scopus 로고    scopus 로고
    • IL-17 family cytokines and the expanding diversity of effector T cell lineages
    • Weaver, C. T., Hatton, R. D., Mangan, P. R., and Harrington, L. E. (2007). IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu. Rev. Immunol. 25, 821-852
    • (2007) Annu. Rev. Immunol. , vol.25 , pp. 821-852
    • Weaver, C.T.1    Hatton, R.D.2    Mangan, P.R.3    Harrington, L.E.4
  • 62
    • 0026542942 scopus 로고
    • Gonococcal lipooligosaccharide sialylation prevents complement dependent killing by immune sera
    • Wetzler, L. M., Barry, K., Blake, M. S., and Gotschlich, E. C. (1992a). Gonococcal lipooligosaccharide sialylation prevents complement dependent killing by immune sera. Infect. Immun. 60, 39-43
    • (1992) Infect. Immun. , vol.60 , pp. 39-43
    • Wetzler, L.M.1    Barry, K.2    Blake, M.S.3    Gotschlich, E.C.4
  • 63
    • 0026707358 scopus 로고
    • Gonococcal porin vaccine evaluation: Comparison of Por proteosomes, liposomes, and blebs isolated from rmp deletion mutants
    • Wetzler, L. M., Blake, M. S., Barry, K., and Gotschlich, E. C. (1992b). Gonococcal porin vaccine evaluation: Comparison of Por proteosomes, liposomes, and blebs isolated from rmp deletion mutants. J. Infect. Dis. 166, 551-555
    • (1992) J. Infect. Dis. , vol.166 , pp. 551-555
    • Wetzler, L.M.1    Blake, M.S.2    Barry, K.3    Gotschlich, E.C.4
  • 64
    • 77953920807 scopus 로고    scopus 로고
    • Sex hormone regulation of innate immunity in the female reproductive tract: the role of epithelial cells in balancing reproductive potential with protection against sexually transmitted pathogens
    • Wira, C. R., Fahey, J. V., Ghosh, M., Patel, M. V., Hickey, D. K., and Ochiel, D. O. (2010). Sex hormone regulation of innate immunity in the female reproductive tract: the role of epithelial cells in balancing reproductive potential with protection against sexually transmitted pathogens. Am. J. Reprod. Immunol. 63, 544-565
    • (2010) Am. J. Reprod. Immunol. , vol.63 , pp. 544-565
    • Wira, C.R.1    Fahey, J.V.2    Ghosh, M.3    Patel, M.V.4    Hickey, D.K.5    Ochiel, D.O.6
  • 65
    • 0038466109 scopus 로고    scopus 로고
    • Oestradiol regulation of antigen presentation by uterine stromal cells: role of transforming growth factor-β production by epithelial cells in mediating antigen-presenting cell function
    • Wira, C. R., and Rossoll, R. M. (2003). Oestradiol regulation of antigen presentation by uterine stromal cells: role of transforming growth factor-β production by epithelial cells in mediating antigen-presenting cell function. Immunology 109, 398-406
    • (2003) Immunology , vol.109 , pp. 398-406
    • Wira, C.R.1    Rossoll, R.M.2
  • 66
    • 0030032275 scopus 로고    scopus 로고
    • Variation of gonococcal lipooligosac-charide structure is due to alterations in poly-G tracts in lgt genes encoding glycosyl transferases
    • Yang, Q. L., and Gotschlich, E. C. (1996). Variation of gonococcal lipooligosac-charide structure is due to alterations in poly-G tracts in lgt genes encoding glycosyl transferases. J. Exp. Med. 183, 323-327
    • (1996) J. Exp. Med. , vol.183 , pp. 323-327
    • Yang, Q.L.1    Gotschlich, E.C.2
  • 68
    • 70350446638 scopus 로고    scopus 로고
    • Opa+ and Opa- isolates of Neisseria meningitidis and Neisseria gonorrhoeae induce sustained proliferative responses in human CD4+ T cells
    • Youssef, A.-R., van der Flier, M., Estevao, S., Hartwig, N. G., van der Ley, P., and Virji, M. (2009). Opa+ and Opa- isolates of Neisseria meningitidis and Neisseria gonorrhoeae induce sustained proliferative responses in human CD4+ T cells. Infect. Immun. 77, 5170-5180
    • (2009) Infect. Immun. , vol.77 , pp. 5170-5180
    • Youssef, A.-R.1    van der Flier, M.2    Estevao, S.3    Hartwig, N.G.4    van der Ley, P.5    Virji, M.6
  • 69
    • 34147126728 scopus 로고    scopus 로고
    • An essential role for IL-17 in preventing pathogen-initiated bone destruction: recruitment of neutrophils to inflamed bone requires IL-17 receptor-dependent signals
    • Yu, J. J., Ruddy, M. J., Wong, G. C., Sfintescu, C., Baker, P. J., Smith, J. B., Evans, R. T., and Gaffen, S. L. (2007). An essential role for IL-17 in preventing pathogen-initiated bone destruction: recruitment of neutrophils to inflamed bone requires IL-17 receptor-dependent signals. Blood 109, 3794-3802.
    • (2007) Blood , vol.109 , pp. 3794-3802
    • Yu, J.J.1    Ruddy, M.J.2    Wong, G.C.3    Sfintescu, C.4    Baker, P.J.5    Smith, J.B.6    Evans, R.T.7    Gaffen, S.L.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.