Synthesis of new vitamin K analogues as steroid and xenobiotic receptor (SXR) agonists: Insights into the biological role of the side chain part of vitamin K

Journal of Medicinal Chemistry

Volumn 54, Issue 13, 2011, Pages 4918-4922

  Suhara, Yoshitomo ^a   Watanabe, Masato ^b   Motoyoshi, Sayaka ^c   Nakagawa, Kimie ^b   Wada, Akimori ^b   Takeda, Kazuyoshi ^a   Takahashi, Kazuhiko ^a   Tokiwa, Hiroaki ^c   Okano, Toshio ^b  

^a YOKOHAMA COLLEGE OF PHARMACY   (Japan)

^b KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

^c RIKKYO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 NAPHTHOQUINONE; CELL NUCLEUS RECEPTOR; MENADIONE; MENAQUINONE; PHYTOMENADIONE; STEROID AND XENOBIOTIC RECEPTOR; UNCLASSIFIED DRUG; VITAMIN K GROUP;

ARTICLE; CRYSTAL STRUCTURE; DRUG STRUCTURE; DRUG SYNTHESIS; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LIGAND BINDING; MOLECULAR DOCKING;

BINDING SITES; BUTADIENES; GENES, REPORTER; HEMITERPENES; HEP G2 CELLS; HUMANS; LIGANDS; LUCIFERASES; PENTANES; RECEPTORS, STEROID; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION, GENETIC; VITAMIN K;

EID: 79960179593     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm200201k     Document Type: Article

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