The role of a new CD44st in increasing the invasion capability of the human breast cancer cell line MCF-7

BMC Cancer

Volumn 11, Issue , 2011, Pages

  Fang, Xin J ^a   Jiang, Hua ^a   Zhao, Xv P ^b   Jiang, Wei M ^a  

^a BENGBU MEDICAL COLLEGE   (China)

^b The First Affiliated Hospital of China Medial University   (China)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; GELATINASE A; GELATINASE B; HERMES ANTIGEN; LIPOFECTAMINE; MITOGEN ACTIVATED PROTEIN KINASE; HYALURONIC ACID; ISOPROTEIN; RAS PROTEIN;

ARTICLE; BREAST CANCER; CANCER INVASION; CD44 GENE; CELL INVASION; CELL STRAIN MCF 7; CELL VIABILITY; CONTROLLED STUDY; DNA VECTOR; EUKARYOTIC CELL; EXON; EXPRESSION VECTOR; GENE; GENE ACTIVITY; GENE EXPRESSION REGULATION; GENE SEQUENCE; GENETIC ANALYSIS; HUMAN; HUMAN CELL; MATRIX METALLOPROTEINASE 2 GENE; MATRIX METALLOPROTEINASE 9 GENE; MOLECULAR CLONING; MOLECULAR DYNAMICS; MULTIDRUG RESISTANCE; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PROTEIN EXPRESSION; RESTRICTION MAPPING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; SIGNAL TRANSDUCTION; STABLE TRANSFECTION; UPREGULATION; WESTERN BLOTTING; ZYMOGRAPHY; ALTERNATIVE RNA SPLICING; BREAST TUMOR; CELL MOTION; CELL STRAIN HL 60; CELL STRAIN K 562; DRUG EFFECT; DRUG RESISTANCE; ENZYME ACTIVATION; FEMALE; GENETICS; METABOLISM; MOLECULAR GENETICS; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

ALTERNATIVE SPLICING; ANTIGENS, CD44; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CLONING, MOLECULAR; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HL-60 CELLS; HUMANS; HYALURONIC ACID; K562 CELLS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR SEQUENCE DATA; NEOPLASM INVASIVENESS; PROTEIN ISOFORMS; RAS PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 79960167042     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-11-290     Document Type: Article

References (33)

1. Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000, 100:57-70. 10.1016/S0092-8674(00)81683-9, 10647931.
2. Screaton GR, Bell MV, Jackson DG, Cornelis FB, Gerth U, Bell JI. Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons. Proc Natl Acad Sci USA 1992, 89:12160-12164. 10.1073/pnas.89.24.12160, 50718, 1465456.
3. Screaton GR, Bell MV, Bell JI, Jackson DG. The identification of a new alternative exon with highly restricted tissue expression in transcripts encoding the mouse Pgp-1 (CD44) homing receptor. J Biol Chem 1993, 268:12235-12238.
4. Naor D, Nedvetzki S. CD44 in rheumatoid arthritis. Arthritis Res Ther 2003, 5:105-115. 165042, 12723975.
5. Xin-Jian F, Wen-L-in X, Xu Z, Hui Q, Chen C, LI-Li F, Qiao-Yun C. Construction of human CD44 eukaryotic expression vector and its expression in mammary carcinoma cells. Jian Su university medical journal 2009, 19:102-106.
6. Fang XJ, Xu WL, Gong JL, Chen C, Fang LL, Chen QY. CD44 variant increases the invasive ability of human breast cancer cell line MCF-7 cells. Zhonghua Zhong Liu Za Zhi 2010, 32(1):22-28.
7. Ponta H, Sherman L, Herrlich PA. CD44: from adhesion molecules to signalling regulators. Nat Rev Mol Cell Biol 2003, 4:33-45. 10.1038/nrm1004, 12511867.
8. Naor D, Nedvetzki S, Golan I, Melnik L, Faitelson Y. CD44 in cancer. Crit Rev Clin Lab Sci 2002, 39:527-579. 10.1080/10408360290795574, 12484499.
9. Underhill C. CD44: the hyaluronan receptor. J Cell Sci 1992, 103:293-298.
10. Rail CJN, Rustgi AK. CD44 isoform expression in primary and metastatic pancreatic adenocarcinoma. Cancer Res 1995, 55:1831-1835.
11. Jiang H, Peterson RS, Wang W, Bartnik E, Knudson CB, Knudson W. A requirement for the CD44 cytoplasmic domain for hyaluronan binding, pericellular matrix assembly, and receptor-mediated endocytosis in COS-7 cells. J Biol Chem 2002, 277:10531-10538. 10.1074/jbc.M108654200, 11792695.
12. Knudson W. tumor-associated hyaluronan providing an extracellular matrix that facilitates invasion. Am J Pathol 1996, 148:1721-1726. 1861627, 8669457.
13. Slevin M, Krupinski J, Gaffney J, Matou S, West D, Delisser H, Savani RC, Kumar S. Hyaluronan-mediated angiogenesis in vascular disease:Uncovering RHAMM and CD44 receptor signaling pathways. Matrix Biol 2007, 26:58-68. 10.1016/j.matbio.2006.08.261, 17055233.
14. Golshani R, Lopez L, Estrella V, Kramer M, Iida N, Lokeshwar VB. Hyaluronic acid synthase-1 expression regulates bladder cancer growth, invasion, and angiogenesis through CD44. Cancer Res 2008, 68:483-491. 10.1158/0008-5472.CAN-07-2140, 18199543.
15. Kleiner DE, Stetler-Stevenson WG. Matrix metalloproteinases and metastasis. Cancer Chemother Pharmacol 1999, 43(Suppl):S42-51.
16. Zhang Y, Thant AA, Machida K, Ichigotani Y, Naito Y, Hiraiwa Y, Senga T, Sohara Y, Matsuda S, Hamaguchi M. Hyaluronan-CD44s signaling regulates matrix metalloproteinase-2 secretion in a human lung carcinoma cell line QG90. Cancer Res 2002, 62:3962-3965.
17. Dufour A, Nicole S, Kuscu C, Zucker S, Cao J. Abstract 533: Critical role of MMP-9 dimers in cell migration: design of inhibitory peptides. Cancer Research 2010, 70(8). Supplement 1.
18. Sohara Y, Ishiguro N, Machida K, Kurata H, Thant AA, Senga T, Matsuda S, Kimata K, Iwata H, and Hamaguchi M. Hyaluronan activates cell motility of v-Src-Transformed cells via Ras-mitogen-activated protein kinase and phosphoinositide3-kinase-Akt in a tumor-specific manner. Mol Biol Cell 2001, 12:1859-1868. 37347, 11408591.
19. Thorne RF, Legg JW, Isacke CM. The role of the CD44 transmembrane and cytoplasmic domains in co-ordinating adhesive and signalling events. J Cell Sci 2004, 117:373-380.
20. Yang JM, Xu Z, Wu H, Zhu H, Wu X, Hait WN. Overexpression of extracellular matrix metalloproteinase inducer in multidrug resistant cancer cells. Mol Cancer Res 2003, 1:420-427.
21. Misra S, Ghatak S, Zoltan-Jones A, Toole BP. Regulation of multi-drug resistance in cancer cells by hyaluronan. J Biol Chem 2003, 278:25285-25288. 10.1074/jbc.C300173200, 12738783.
22. Miletti-González KE, Chen S, Muthukumaran N, Saglimbeni GN, Wu X, Yang J, Apolito K, Shih WJ, Hait WN, Rodríguez-Rodríguez L. The CD44 receptor interacts with P-Glycoprotein to promote cell migration and invasion in cancer. Cancer Res 2005, 65:6660-6667. 10.1158/0008-5472.CAN-04-3478, 16061646.
23. Slomiany MG, Grass GD, Robertson AD, Yang XY, Maria BL, Beeson C, Toole BP. Hyaluronan, CD44, and emmprin regulate lactate efflux and membrane localization of monocarboxylate transporters in human breast carcinoma cells. Cancer Res 2009, 69:1293-1301. 10.1158/0008-5472.CAN-08-2491, 19176383.
24. Slomiany MG, Dai L, Bomar PA, Knackstedt TJ, Kranc DA, Tolliver L, Maria BL, Toole BP. Abrogating drug resistance in malignant peripheral nerve sheath tumors by disrupting hyaluronan-CD44 interactions with small hyaluronan oligosaccharides. Cancer Res 2009, 69:4992-4998. 10.1158/0008-5472.CAN-09-0143, 19470767.
25. Cordo RRI, Garcia MG, Alaniz L, Blanco G, Alvarez E, Hajos SE. Hyaluronan oligosaccharides sensitize lymphoma resistant cell lines to vincristine by modulating P-glycoprotein activity and PI3K/Akt pathway. Int J Cancer 2008, 122:1012-1018.
26. Ohashi R, Takahashi F, Cui R, Yoshioka M, Gu T, Sasaki S, Tominaga S, Nishio K, and Takahashi K. Interaction between CD44 and hyaluronate induces chemoresistance in non-small cell lung cancer cell. Cancer Lett 2007, 252:225-234. 10.1016/j.canlet.2006.12.025, 17276588.
27. Wang SJ, Peyrollier K, and Bourguignon LY. The influence of hyaluronan-CD44 interaction on topoisomerase II activity and etoposide cytotoxicity in head and neck cancer. Arch Otolaryngol Head Neck Surg 2007, 133:281-288. 10.1001/archotol.133.3.281, 17372087.
28. Bourguignon LY, Peyrollier K, Xia W, Gilad E. Hyaluronan-CD44 interaction activates stem cell marker nanog, Stat-3-mediated MDR1 gene expression, and ankyrin-regulated multidrug efflux in breast and ovarian tumor cells. J Biol Chem 2008, 283:17635-17651. 10.1074/jbc.M800109200, 2427357,2427357, 18441325.
29. Huang D, Ding Y, Luo WM, Bender S, Qian CN, Kort E, Zhang ZF, VandenBeldt K, Duesbery NS, Resau JH, Teh BT. Inhibition of MAPK kinase signaling pathways suppressed renal cell carcinoma growth and angiogenesis in vivo. Cancer Res 2008, 68:81-88. 10.1158/0008-5472.CAN-07-5311, 18172299.
30. Bourguignon LY. Hyaluronan-mediated CD44 activation of Rho GTPase signaling and cytoskeleton function promotes tumor progression. Semin Cancer Biol 2008, 18:251-259. 10.1016/j.semcancer.2008.03.007, 2505114, 18450475.
31. Götte M, Yip GW. Heparanase, hyaluronan, and CD44 in Cancers: a breast carcinoma perspective. Cancer Res 2006, 66:10233-10237. 10.1158/0008-5472.CAN-06-1464, 17079438.
32. Sheridan C, Kishimoto H, Fuchs RK, Mehrotra S, Bhat-Nakshatri P, Turner CH, Goulet R, Badve S, Nakshatri H. CD44+/CD24-breast cancer cells exhibit enhanced invasive properties, an early step necessary for metastasis. Breast Cancer Res 2006, 8:R59. 10.1186/bcr1610, 1779499, 17062128.
33. Lopez JI, Camenisch TD, Stevens MV, Sands BJ, McDonald J, Schroeder JA. CD44 attenuates metastatic invasion during breast cancer progression. Cancer Res 2005, 65:6755-6763. 10.1158/0008-5472.CAN-05-0863, 16061657.