메뉴 건너뛰기




Volumn 72, Issue 8, 2011, Pages 641-651

Lack of an association between interleukin-6 gene promoter polymorphisms (-174G/C, -572G/C) and ischemic heart disease and/or ischemic stroke: A meta-analysis

Author keywords

Interleukin 6; Ischemic heart disease; Ischemic stroke; Meta analysis; Single nucleotide polymorphism

Indexed keywords

INTERLEUKIN 6;

EID: 79960159518     PISSN: 01988859     EISSN: 18791166     Source Type: Journal    
DOI: 10.1016/j.humimm.2011.03.019     Document Type: Article
Times cited : (25)

References (66)
  • 1
    • 0025190892 scopus 로고
    • Interleukin-6 and the acute phase response
    • Heinrich P.C., Castell J.V., Andus T. Interleukin-6 and the acute phase response. Biochem J 1990, 265:621-636.
    • (1990) Biochem J , vol.265 , pp. 621-636
    • Heinrich, P.C.1    Castell, J.V.2    Andus, T.3
  • 3
    • 19344365098 scopus 로고    scopus 로고
    • Proinflammatory cytokines and myocardial viability in patients after acute myocardial infarction
    • Kosmala W., Przewlocka-Kosmala M., Mazurek W. Proinflammatory cytokines and myocardial viability in patients after acute myocardial infarction. Int J Cardiol 2005, 101:449-456.
    • (2005) Int J Cardiol , vol.101 , pp. 449-456
    • Kosmala, W.1    Przewlocka-Kosmala, M.2    Mazurek, W.3
  • 5
    • 0028261395 scopus 로고
    • Interleukin 6 gene transcripts are expressed in human atherosclerotic lesions
    • Seino Y., Ikeda U., Ikeda M., Yamamoto K., Misawa Y., Hasegawa T., et al. Interleukin 6 gene transcripts are expressed in human atherosclerotic lesions. Cytokines 1994, 6:87-91.
    • (1994) Cytokines , vol.6 , pp. 87-91
    • Seino, Y.1    Ikeda, U.2    Ikeda, M.3    Yamamoto, K.4    Misawa, Y.5    Hasegawa, T.6
  • 6
    • 0346787875 scopus 로고    scopus 로고
    • Biochemical changes and inflammatory response as markers for brain ischaemia: molecular markers of diagnostic utility and prognosis in human clinical practice
    • Castillo J., Rodríguez I. Biochemical changes and inflammatory response as markers for brain ischaemia: molecular markers of diagnostic utility and prognosis in human clinical practice. Cerebrovasc Dis 2004, 17(suppl 1):7-18.
    • (2004) Cerebrovasc Dis , vol.17 , Issue.SUPPL. , pp. 7-18
    • Castillo, J.1    Rodríguez, I.2
  • 7
    • 35648965192 scopus 로고    scopus 로고
    • Interleukin-6 174G/C polymorphism and ischemic stroke: a systematic review
    • Tso A.R., Merino J.G., Warach S. Interleukin-6 174G/C polymorphism and ischemic stroke: a systematic review. Stroke 2007, 38:3070-3075.
    • (2007) Stroke , vol.38 , pp. 3070-3075
    • Tso, A.R.1    Merino, J.G.2    Warach, S.3
  • 8
    • 0034681920 scopus 로고    scopus 로고
    • Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men
    • Ridker P.M., Rifai N., Stampfer M.J., Hennekens C.H. Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men. Circulation 2000, 101:1767-1772.
    • (2000) Circulation , vol.101 , pp. 1767-1772
    • Ridker, P.M.1    Rifai, N.2    Stampfer, M.J.3    Hennekens, C.H.4
  • 9
    • 0034945885 scopus 로고    scopus 로고
    • Interleukin-6 gene polymorphisms and susceptibility to myocardial infarction: the ECTIM study. Etude Cas-Témoin de l'infarctus du Myocarde
    • Georges J.L., Loukaci V., Poirier O., Evans A., Luc G., Arveiler D., et al. Interleukin-6 gene polymorphisms and susceptibility to myocardial infarction: the ECTIM study. Etude Cas-Témoin de l'infarctus du Myocarde. J Mol Med 2001, 79:300-305.
    • (2001) J Mol Med , vol.79 , pp. 300-305
    • Georges, J.L.1    Loukaci, V.2    Poirier, O.3    Evans, A.4    Luc, G.5    Arveiler, D.6
  • 10
    • 72949091661 scopus 로고    scopus 로고
    • The association of functional polymorphisms of IL-6 gene promoter with ischemic stroke: analysis in two Chinese populations
    • Tong Y., Wang Z., Geng Y., Liu J., Zhang R., Lin Q., et al. The association of functional polymorphisms of IL-6 gene promoter with ischemic stroke: analysis in two Chinese populations. Biochem Biophys Res Commun 2010, 391:481-485.
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 481-485
    • Tong, Y.1    Wang, Z.2    Geng, Y.3    Liu, J.4    Zhang, R.5    Lin, Q.6
  • 11
    • 0032189103 scopus 로고    scopus 로고
    • The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis
    • Fishman D., Faulds G., Jeffery R., Mohamed-Ali V., Yudkin J.S., Humphries S., et al. The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. J Clin Invest 1998, 102:1369-1376.
    • (1998) J Clin Invest , vol.102 , pp. 1369-1376
    • Fishman, D.1    Faulds, G.2    Jeffery, R.3    Mohamed-Ali, V.4    Yudkin, J.S.5    Humphries, S.6
  • 12
    • 0040780540 scopus 로고    scopus 로고
    • Cooperative influence of genetic polymorphisms on interleukin 6 transcriptional regulation
    • Terry C.F., Loukaci V., Green F.R. Cooperative influence of genetic polymorphisms on interleukin 6 transcriptional regulation. J Biol Chem 2000, 275:18138-18144.
    • (2000) J Biol Chem , vol.275 , pp. 18138-18144
    • Terry, C.F.1    Loukaci, V.2    Green, F.R.3
  • 13
    • 43449128097 scopus 로고    scopus 로고
    • Association of serum interleukin-6 concentration with a functional IL6 -6331T>C polymorphism
    • Smith A.J., D'Aiuto F., Palmen J., Cooper J.A., Samuel J., Thompson S., et al. Association of serum interleukin-6 concentration with a functional IL6 -6331T>C polymorphism. Clin Chem 2008, 54:841-850.
    • (2008) Clin Chem , vol.54 , pp. 841-850
    • Smith, A.J.1    D'Aiuto, F.2    Palmen, J.3    Cooper, J.A.4    Samuel, J.5    Thompson, S.6
  • 14
    • 34547862388 scopus 로고    scopus 로고
    • Genetic polymorphism in the pregnancy-associated plasma protein-A associated with acute myocardial infarction
    • Park S., Youn J.C., Shin D.J., Park C.M., Kim J.S., Ko Y.G., et al. Genetic polymorphism in the pregnancy-associated plasma protein-A associated with acute myocardial infarction. Coron Artery Dis 2007, 18:417-422.
    • (2007) Coron Artery Dis , vol.18 , pp. 417-422
    • Park, S.1    Youn, J.C.2    Shin, D.J.3    Park, C.M.4    Kim, J.S.5    Ko, Y.G.6
  • 16
    • 33747198521 scopus 로고    scopus 로고
    • Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery
    • Podgoreanu M.V., White W.D., Morris R.W., Mathew J.P., Stafford-Smith M., Welsby I.J., et al. Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery. Circulation 2006, 114(1 suppl):I275-I281.
    • (2006) Circulation , vol.114 , Issue.SUPPL.
    • Podgoreanu, M.V.1    White, W.D.2    Morris, R.W.3    Mathew, J.P.4    Stafford-Smith, M.5    Welsby, I.J.6
  • 17
    • 20844445291 scopus 로고    scopus 로고
    • Effect of interleukin-6 promoter polymorphisms in survivors of myocardial infarction and matched controls in the North and South of Europe. The HIFMECH Study
    • Kelberman D., Hawe E., Luong L.A., Mohamed-Ali V., Lundman P., Tornvall P., et al. Effect of interleukin-6 promoter polymorphisms in survivors of myocardial infarction and matched controls in the North and South of Europe. The HIFMECH Study. Thromb Haemost 2004, 92:1122-1128.
    • (2004) Thromb Haemost , vol.92 , pp. 1122-1128
    • Kelberman, D.1    Hawe, E.2    Luong, L.A.3    Mohamed-Ali, V.4    Lundman, P.5    Tornvall, P.6
  • 18
    • 0035661847 scopus 로고    scopus 로고
    • The interleukin-6 -174 G/C promoter polymorphism is associated with risk of coronary heart disease and systolic blood pressure in healthy men
    • Humphries S.E., Luong L.A., Ogg M.S., Hawe E., Miller G.J. The interleukin-6 -174 G/C promoter polymorphism is associated with risk of coronary heart disease and systolic blood pressure in healthy men. Eur Heart J 2001, 22:2243-2252.
    • (2001) Eur Heart J , vol.22 , pp. 2243-2252
    • Humphries, S.E.1    Luong, L.A.2    Ogg, M.S.3    Hawe, E.4    Miller, G.J.5
  • 19
    • 77952585414 scopus 로고    scopus 로고
    • Interleukin-1 beta and interleukin-6 gene polymorphism associations with angiographically assessed coronary artery disease in Brazilians
    • Rios D.L., Cerqueira C.C., Bonfim-Silva R., Araujo L.J., Pereira J.F., Gadelha S.R., et al. Interleukin-1 beta and interleukin-6 gene polymorphism associations with angiographically assessed coronary artery disease in Brazilians. Cytokines 2010, 50:292-296.
    • (2010) Cytokines , vol.50 , pp. 292-296
    • Rios, D.L.1    Cerqueira, C.C.2    Bonfim-Silva, R.3    Araujo, L.J.4    Pereira, J.F.5    Gadelha, S.R.6
  • 20
    • 77956176283 scopus 로고    scopus 로고
    • TNF-alpha -308G>A and IL-6 -174 G>C polymorphisms in Tunisian patients with coronary artery disease
    • Ghazouani L., Ben Hadj Khalifa S., Abboud N., Hamda K.B., Khalfallah A.B., Brahim N., et al. TNF-alpha -308G>A and IL-6 -174 G>C polymorphisms in Tunisian patients with coronary artery disease. Clin Biochem 2010, 43:1085-1089.
    • (2010) Clin Biochem , vol.43 , pp. 1085-1089
    • Ghazouani, L.1    Ben Hadj Khalifa, S.2    Abboud, N.3    Hamda, K.B.4    Khalfallah, A.B.5    Brahim, N.6
  • 21
    • 60649121402 scopus 로고    scopus 로고
    • Association between inflammatory gene polymorphisms and coronary artery disease in an Indian population
    • Banerjee I., Pandey U., Hasan O.M., Parihar R., Tripathi V., Ganesh S. Association between inflammatory gene polymorphisms and coronary artery disease in an Indian population. J Thromb Thrombolysis 2009, 27:88-94.
    • (2009) J Thromb Thrombolysis , vol.27 , pp. 88-94
    • Banerjee, I.1    Pandey, U.2    Hasan, O.M.3    Parihar, R.4    Tripathi, V.5    Ganesh, S.6
  • 22
    • 41849119426 scopus 로고    scopus 로고
    • Synergistic effects of the polymorphisms in the PAI-1 and IL-6 genes with smoking in determining their associated risk with coronary artery disease
    • Sarecka B., Zak I., Krauze J. Synergistic effects of the polymorphisms in the PAI-1 and IL-6 genes with smoking in determining their associated risk with coronary artery disease. Clin Biochem 2008, 41:467-473.
    • (2008) Clin Biochem , vol.41 , pp. 467-473
    • Sarecka, B.1    Zak, I.2    Krauze, J.3
  • 23
    • 0036373824 scopus 로고    scopus 로고
    • The interleukin-6 G(-174)C promoter polymorphism in the LURIC cohort: no association with plasma interleukin-6, coronary artery disease, and myocardial infarction
    • Nauck M., Winkelmann B.R., Hoffmann M.M., Bohm B.O., Wieland H., Marz W. The interleukin-6 G(-174)C promoter polymorphism in the LURIC cohort: no association with plasma interleukin-6, coronary artery disease, and myocardial infarction. J Mol Med 2002, 80:507-513.
    • (2002) J Mol Med , vol.80 , pp. 507-513
    • Nauck, M.1    Winkelmann, B.R.2    Hoffmann, M.M.3    Bohm, B.O.4    Wieland, H.5    Marz, W.6
  • 24
    • 0036123849 scopus 로고    scopus 로고
    • Interleukin-6 -174G>C polymorphism and risk of coronary heart disease in West of Scotland coronary prevention study (WOSCOPS)
    • Basso F., Lowe G.D., Rumley A., McMahon A.D., Humphries S.E. Interleukin-6 -174G>C polymorphism and risk of coronary heart disease in West of Scotland coronary prevention study (WOSCOPS). Arterioscler Thromb Vasc Biol 2002, 22:599-604.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 599-604
    • Basso, F.1    Lowe, G.D.2    Rumley, A.3    McMahon, A.D.4    Humphries, S.E.5
  • 26
    • 40349105705 scopus 로고    scopus 로고
    • Comparison of serum levels of inflammatory markers and allelic variant of interleukin-6 in patients with acute coronary syndrome and stable angina pectoris
    • Ozdemir O., Gundogdu F., Karakelleoglu S., Sevimli S., Pirim I., Acikel M., et al. Comparison of serum levels of inflammatory markers and allelic variant of interleukin-6 in patients with acute coronary syndrome and stable angina pectoris. Coron Artery Dis 2008, 19:15-19.
    • (2008) Coron Artery Dis , vol.19 , pp. 15-19
    • Ozdemir, O.1    Gundogdu, F.2    Karakelleoglu, S.3    Sevimli, S.4    Pirim, I.5    Acikel, M.6
  • 27
    • 58149098228 scopus 로고    scopus 로고
    • The additive contribution from inflammatory genetic markers on the severity of cardiovascular disease
    • Berg K.K., Madsen H.O., Garred P., Wiseth R., Gunnes S., Videm V. The additive contribution from inflammatory genetic markers on the severity of cardiovascular disease. Scand J Immunol 2009, 69:36-42.
    • (2009) Scand J Immunol , vol.69 , pp. 36-42
    • Berg, K.K.1    Madsen, H.O.2    Garred, P.3    Wiseth, R.4    Gunnes, S.5    Videm, V.6
  • 28
    • 52149111839 scopus 로고    scopus 로고
    • Serum interleukin-6 levels, not genotype, correlate with coronary plaque complexity
    • Kuo L.T., Yang N.I., Cherng W.J., Verma S., Hung M.J., Wang S.Y., et al. Serum interleukin-6 levels, not genotype, correlate with coronary plaque complexity. Int Heart J 2008, 49:391-402.
    • (2008) Int Heart J , vol.49 , pp. 391-402
    • Kuo, L.T.1    Yang, N.I.2    Cherng, W.J.3    Verma, S.4    Hung, M.J.5    Wang, S.Y.6
  • 29
    • 38949097096 scopus 로고    scopus 로고
    • Interleukin-6-572C>G polymorphism-association with inflammatory variables in Korean men with coronary artery disease
    • Jang Y., Kim O.Y., Hyun Y.J., Chae J.S., Koh S.J., Heo Y.M., et al. Interleukin-6-572C>G polymorphism-association with inflammatory variables in Korean men with coronary artery disease. Transl Res 2008, 151:154-161.
    • (2008) Transl Res , vol.151 , pp. 154-161
    • Jang, Y.1    Kim, O.Y.2    Hyun, Y.J.3    Chae, J.S.4    Koh, S.J.5    Heo, Y.M.6
  • 30
    • 26044482278 scopus 로고    scopus 로고
    • Additive effects of the chemokine receptor 2, vitamin D receptor, interleukin-6 polymorphisms and cardiovascular risk factors on the prevalence of myocardial infarction in patients below 65 years
    • Ortlepp J.R., Krantz C., Kimmel M., von Korff A., Vesper K., Schmitz F., et al. Additive effects of the chemokine receptor 2, vitamin D receptor, interleukin-6 polymorphisms and cardiovascular risk factors on the prevalence of myocardial infarction in patients below 65 years. Int J Cardiol 2005, 105:90-95.
    • (2005) Int J Cardiol , vol.105 , pp. 90-95
    • Ortlepp, J.R.1    Krantz, C.2    Kimmel, M.3    von Korff, A.4    Vesper, K.5    Schmitz, F.6
  • 31
    • 69249154579 scopus 로고    scopus 로고
    • Influence of interleukin-6 G-174C gene polymorphism on coronary artery disease, cardiovascular complications and mortality in dialysis patients
    • Aker S., Bantis C., Reis P., Kuhr N., Schwandt C., Grabensee B., et al. Influence of interleukin-6 G-174C gene polymorphism on coronary artery disease, cardiovascular complications and mortality in dialysis patients. Nephrol Dial Transplant 2009, 24:2847-2851.
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 2847-2851
    • Aker, S.1    Bantis, C.2    Reis, P.3    Kuhr, N.4    Schwandt, C.5    Grabensee, B.6
  • 32
    • 58549101885 scopus 로고    scopus 로고
    • Carrier-state of two or three polymorphic variants of MTHFR, IL-6 and ICAM1 genes increases the risk of coronary artery disease
    • Sarecka-Hujar B., Zak I., Krauze J. Carrier-state of two or three polymorphic variants of MTHFR, IL-6 and ICAM1 genes increases the risk of coronary artery disease. Kardiol Pol 2008, 66:1269-1277.
    • (2008) Kardiol Pol , vol.66 , pp. 1269-1277
    • Sarecka-Hujar, B.1    Zak, I.2    Krauze, J.3
  • 33
    • 28444457805 scopus 로고    scopus 로고
    • Interleukin-6 gene polymorphism is an age-dependent risk factor for myocardial infarction in men
    • Chiappelli M., Tampieri C., Tumini E., Porcellini E., Caldarera C.M., Nanni S., et al. Interleukin-6 gene polymorphism is an age-dependent risk factor for myocardial infarction in men. Int J Immunogenet 2005, 32:349-353.
    • (2005) Int J Immunogenet , vol.32 , pp. 349-353
    • Chiappelli, M.1    Tampieri, C.2    Tumini, E.3    Porcellini, E.4    Caldarera, C.M.5    Nanni, S.6
  • 34
    • 4344617212 scopus 로고    scopus 로고
    • The concomitant presence of polymorphic alleles of interleukin-1beta, interleukin-6 and apolipoprotein E is associated with an increased risk of myocardial infarction in elderly men. Results from a pilot study
    • Licastro F., Chiappelli M., Caldarera C.M., Tampieri C., Nanni S., Gallina M., et al. The concomitant presence of polymorphic alleles of interleukin-1beta, interleukin-6 and apolipoprotein E is associated with an increased risk of myocardial infarction in elderly men. Results from a pilot study. Mech Ageing Dev 2004, 125:575-579.
    • (2004) Mech Ageing Dev , vol.125 , pp. 575-579
    • Licastro, F.1    Chiappelli, M.2    Caldarera, C.M.3    Tampieri, C.4    Nanni, S.5    Gallina, M.6
  • 35
    • 4744362285 scopus 로고    scopus 로고
    • Proinflammatory genetic profiles in subjects with history of ischemic stroke
    • Flex A., Gaetani E., Papaleo P., Straface G., Proia A.S., Pecorini G., et al. Proinflammatory genetic profiles in subjects with history of ischemic stroke. Stroke 2004, 35:2270-2275.
    • (2004) Stroke , vol.35 , pp. 2270-2275
    • Flex, A.1    Gaetani, E.2    Papaleo, P.3    Straface, G.4    Proia, A.S.5    Pecorini, G.6
  • 36
    • 0037383552 scopus 로고    scopus 로고
    • Synergistic effect of -174 G/C polymorphism of the interleukin-6 gene promoter and 469 e/K polymorphism of the intercellular adhesion molecule-1 gene in Italian patients with history of ischemic stroke
    • Pola R., Flex A., Gaetani E., Flore R., Serricchio M., Pola P. Synergistic effect of -174 G/C polymorphism of the interleukin-6 gene promoter and 469 e/K polymorphism of the intercellular adhesion molecule-1 gene in Italian patients with history of ischemic stroke. Stroke 2003, 34:881-885.
    • (2003) Stroke , vol.34 , pp. 881-885
    • Pola, R.1    Flex, A.2    Gaetani, E.3    Flore, R.4    Serricchio, M.5    Pola, P.6
  • 38
    • 0242317416 scopus 로고    scopus 로고
    • The (-174) G/C polymorphism in the interleukin-6 gene is associated with the severity of acute cerebrovascular events
    • Greisenegger S., Endler G., Haering D., Schillinger M., Lang W., Lalouschek W., et al. The (-174) G/C polymorphism in the interleukin-6 gene is associated with the severity of acute cerebrovascular events. Thromb Res 2003, 110:181-186.
    • (2003) Thromb Res , vol.110 , pp. 181-186
    • Greisenegger, S.1    Endler, G.2    Haering, D.3    Schillinger, M.4    Lang, W.5    Lalouschek, W.6
  • 39
    • 24144436042 scopus 로고    scopus 로고
    • Systematic review and meta-analysis of the association between {beta}2-adrenoceptor polymorphisms and asthma: a HuGE review
    • Thakkinstian A., McEvoy M., Minelli C., Gibson P., Hancox B., Duffy D., et al. Systematic review and meta-analysis of the association between {beta}2-adrenoceptor polymorphisms and asthma: a HuGE review. Am J Epidemiol 2005, 162:201-211.
    • (2005) Am J Epidemiol , vol.162 , pp. 201-211
    • Thakkinstian, A.1    McEvoy, M.2    Minelli, C.3    Gibson, P.4    Hancox, B.5    Duffy, D.6
  • 40
    • 33749363062 scopus 로고    scopus 로고
    • Interleukin-1beta and interleukin-1 receptor antagonist gene polymorphisms and gastric cancer: a meta-analysis
    • Camargo M.C., Mera R., Correa P., Peek R.M., Fontham E.T., Goodman K.J., et al. Interleukin-1beta and interleukin-1 receptor antagonist gene polymorphisms and gastric cancer: a meta-analysis. Cancer Epidemiol Biomarkers Prev 2006, 15:1674-1687.
    • (2006) Cancer Epidemiol Biomarkers Prev , vol.15 , pp. 1674-1687
    • Camargo, M.C.1    Mera, R.2    Correa, P.3    Peek, R.M.4    Fontham, E.T.5    Goodman, K.J.6
  • 41
    • 0344464788 scopus 로고    scopus 로고
    • Interleukin-6 serum levels and genotypes influence the risk for myocardial infarction
    • Bennet A.M., Prince J.A., Fei G.Z., Lyrenäs L., Huang Y., Wiman B., et al. Interleukin-6 serum levels and genotypes influence the risk for myocardial infarction. Atherosclerosis 2003, 171:359-367.
    • (2003) Atherosclerosis , vol.171 , pp. 359-367
    • Bennet, A.M.1    Prince, J.A.2    Fei, G.Z.3    Lyrenäs, L.4    Huang, Y.5    Wiman, B.6
  • 42
    • 37349043910 scopus 로고    scopus 로고
    • Inflammatory system gene polymorphism and the risk of stroke: a case-control study in an Indian population
    • Banerjee I., Gupta V., Ahmed T., Faizaan M., Agarwal P., Ganesh S. Inflammatory system gene polymorphism and the risk of stroke: a case-control study in an Indian population. Brain Res Bull 2008, 75:158-165.
    • (2008) Brain Res Bull , vol.75 , pp. 158-165
    • Banerjee, I.1    Gupta, V.2    Ahmed, T.3    Faizaan, M.4    Agarwal, P.5    Ganesh, S.6
  • 43
    • 0037098199 scopus 로고    scopus 로고
    • Quantifying heterogeneity in a meta-analysis
    • Higgins J.P., Thompson S.G. Quantifying heterogeneity in a meta-analysis. Stat Med 2002, 21:1539-1558.
    • (2002) Stat Med , vol.21 , pp. 1539-1558
    • Higgins, J.P.1    Thompson, S.G.2
  • 45
    • 84959801619 scopus 로고
    • Statistical aspects of the analysis of data from retrospective studies of disease
    • Mantel N., Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 1959, 22:719-748.
    • (1959) J Natl Cancer Inst , vol.22 , pp. 719-748
    • Mantel, N.1    Haenszel, W.2
  • 47
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • Egger M., Davey Smith G., Schneider M., Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997, 315:629-634.
    • (1997) BMJ , vol.315 , pp. 629-634
    • Egger, M.1    Davey Smith, G.2    Schneider, M.3    Minder, C.4
  • 48
    • 77649251844 scopus 로고    scopus 로고
    • Association between the interleukin-6 gene -572G/C and -597G/A polymorphisms and coronary heart disease in the Han Chinese
    • Jia X., Tian Y., Wang Y., Deng X., Dong Z., Scafa N., et al. Association between the interleukin-6 gene -572G/C and -597G/A polymorphisms and coronary heart disease in the Han Chinese. Med Sci Monit 2010, 16:CR103-CR108.
    • (2010) Med Sci Monit , vol.16
    • Jia, X.1    Tian, Y.2    Wang, Y.3    Deng, X.4    Dong, Z.5    Scafa, N.6
  • 49
    • 14044251443 scopus 로고    scopus 로고
    • The -174G/C polymorphism of the interleukin 6 gene is a hallmark of lacunar stroke and not other ischemic stroke phenotypes
    • Chamorro A., Revilla M., Obach V., Vargas M., Planas A.M. The -174G/C polymorphism of the interleukin 6 gene is a hallmark of lacunar stroke and not other ischemic stroke phenotypes. Cerebrovasc Dis 2005, 19:91-95.
    • (2005) Cerebrovasc Dis , vol.19 , pp. 91-95
    • Chamorro, A.1    Revilla, M.2    Obach, V.3    Vargas, M.4    Planas, A.M.5
  • 50
    • 14844302204 scopus 로고    scopus 로고
    • The IL-6 G-174C polymorphism may be associated with ischaemic stroke in patients without a history of hypertension
    • Balding J., Livingstone W.J., Pittock S.J., Mynett-Johnson L., Ahern T., Hodgson A., et al. The IL-6 G-174C polymorphism may be associated with ischaemic stroke in patients without a history of hypertension. Ir J Med Sci 2004, 173:200-203.
    • (2004) Ir J Med Sci , vol.173 , pp. 200-203
    • Balding, J.1    Livingstone, W.J.2    Pittock, S.J.3    Mynett-Johnson, L.4    Ahern, T.5    Hodgson, A.6
  • 51
    • 4644262151 scopus 로고    scopus 로고
    • No association of interleukin-6 gene polymorphism (-174 G/C) with myocardial infarction or traditional cardiovascular risk factors
    • Lieb W., Pavlik R., Erdmann J., Mayer B., Holmer S.R., Fischer M., et al. No association of interleukin-6 gene polymorphism (-174 G/C) with myocardial infarction or traditional cardiovascular risk factors. Int J Cardiol 2004, 97:205-212.
    • (2004) Int J Cardiol , vol.97 , pp. 205-212
    • Lieb, W.1    Pavlik, R.2    Erdmann, J.3    Mayer, B.4    Holmer, S.R.5    Fischer, M.6
  • 52
    • 34547502657 scopus 로고    scopus 로고
    • No association of interleukin-6 gene polymorphism (-174 G/C) with premature coronary artery disease in a Turkish cohort
    • Sekuri C., Cam F.S., Sagcan A., Ercan E., Tengiz I., Alioglu E., et al. No association of interleukin-6 gene polymorphism (-174 G/C) with premature coronary artery disease in a Turkish cohort. Coron Artery Dis 2007, 18:333-337.
    • (2007) Coron Artery Dis , vol.18 , pp. 333-337
    • Sekuri, C.1    Cam, F.S.2    Sagcan, A.3    Ercan, E.4    Tengiz, I.5    Alioglu, E.6
  • 53
    • 27944432628 scopus 로고    scopus 로고
    • Interaction between inflammation-related gene polymorphisms and cigarette smoking on the risk of myocardial infarction in the Physician's Health Study
    • Rosner S.A., Ridker P.M., Zee R.Y., Cook N.R. Interaction between inflammation-related gene polymorphisms and cigarette smoking on the risk of myocardial infarction in the Physician's Health Study. Hum Genet 2005, 118:287-294.
    • (2005) Hum Genet , vol.118 , pp. 287-294
    • Rosner, S.A.1    Ridker, P.M.2    Zee, R.Y.3    Cook, N.R.4
  • 54
    • 12844273455 scopus 로고    scopus 로고
    • Role of the interleukin-6 -174 G>C gene polymorphism in retinal artery occlusion
    • Weger M., Steinbrugger I., Haas A., Marz W., El-Shabrawi Y., Weger W., et al. Role of the interleukin-6 -174 G>C gene polymorphism in retinal artery occlusion. Stroke 2005, 36:249-252.
    • (2005) Stroke , vol.36 , pp. 249-252
    • Weger, M.1    Steinbrugger, I.2    Haas, A.3    Marz, W.4    El-Shabrawi, Y.5    Weger, W.6
  • 55
  • 56
    • 18844401943 scopus 로고    scopus 로고
    • Interleukin-6 polymorphism: a genetic risk factor for cardiac transplant related coronary vasculopathy?
    • Densem C.G., Ray M., Hutchinson I.V., Yonan N., Brooks N.H. Interleukin-6 polymorphism: a genetic risk factor for cardiac transplant related coronary vasculopathy?. J Heart Lung Transplant 2005, 24:559-565.
    • (2005) J Heart Lung Transplant , vol.24 , pp. 559-565
    • Densem, C.G.1    Ray, M.2    Hutchinson, I.V.3    Yonan, N.4    Brooks, N.H.5
  • 57
    • 77952551250 scopus 로고    scopus 로고
    • A meta-analysis of interleukin-6 promoter polymorphisms on risk of hip and knee osteoarthritis
    • Valdes A.M., Arden N.K., Tamm A., Kisand K., Doherty S., Pola E., et al. A meta-analysis of interleukin-6 promoter polymorphisms on risk of hip and knee osteoarthritis. Osteoarthritis Cartilage 2010, 18:699-704.
    • (2010) Osteoarthritis Cartilage , vol.18 , pp. 699-704
    • Valdes, A.M.1    Arden, N.K.2    Tamm, A.3    Kisand, K.4    Doherty, S.5    Pola, E.6
  • 58
    • 33644820475 scopus 로고    scopus 로고
    • Interleukin 6 -174 g/c promoter polymorphism and risk of coronary heart disease: results from the Rotterdam study and a meta-analysis
    • Sie M.P., Sayed-Tabatabaei F.A., Oei H.H., Uitterlinden A.G., Pols H.A., Hofman A., et al. Interleukin 6 -174 g/c promoter polymorphism and risk of coronary heart disease: results from the Rotterdam study and a meta-analysis. Arterioscler Thromb Vasc Biol 2006, 26:212-217.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 212-217
    • Sie, M.P.1    Sayed-Tabatabaei, F.A.2    Oei, H.H.3    Uitterlinden, A.G.4    Pols, H.A.5    Hofman, A.6
  • 59
    • 0035889519 scopus 로고    scopus 로고
    • Relation of the -174 G/C polymorphism of interleukin-6 to interleukin-6 plasma levels and to length of hospitalization after surgical coronary revascularization
    • Burzotta F., Iacoviello L., Di Castelnuovo A., Glieca F., Luciani N., Zamparelli R., et al. Relation of the -174 G/C polymorphism of interleukin-6 to interleukin-6 plasma levels and to length of hospitalization after surgical coronary revascularization. Am J Cardiol 2001, 88:1125-1128.
    • (2001) Am J Cardiol , vol.88 , pp. 1125-1128
    • Burzotta, F.1    Iacoviello, L.2    Di Castelnuovo, A.3    Glieca, F.4    Luciani, N.5    Zamparelli, R.6
  • 60
    • 0034938412 scopus 로고    scopus 로고
    • Elevated interleukin-6 plasma levels are regulated by the promoter region polymorphism of the IL6 gene in primary Sjogren's syndrome and correlate with the clinical manifestations of the disease
    • Hulkkonen J., Pertovaara M., Antonen J., Pasternack A., Hurme M. Elevated interleukin-6 plasma levels are regulated by the promoter region polymorphism of the IL6 gene in primary Sjogren's syndrome and correlate with the clinical manifestations of the disease. Rheumatol Oxf 2001, 40:656-661.
    • (2001) Rheumatol Oxf , vol.40 , pp. 656-661
    • Hulkkonen, J.1    Pertovaara, M.2    Antonen, J.3    Pasternack, A.4    Hurme, M.5
  • 61
    • 0037321041 scopus 로고    scopus 로고
    • Interleukin-6 promoter polymorphism modulates the effects of heavy alcohol consumption on early carotid artery atherosclerosis: the Carotid Atherosclerosis Progression Study (CAPS)
    • Jerrard-Dunne P., Sitzer M., Risley P., Steckel D.A., Buehler A., von Kegler S., et al. Interleukin-6 promoter polymorphism modulates the effects of heavy alcohol consumption on early carotid artery atherosclerosis: the Carotid Atherosclerosis Progression Study (CAPS). Stroke 2003, 34:402-407.
    • (2003) Stroke , vol.34 , pp. 402-407
    • Jerrard-Dunne, P.1    Sitzer, M.2    Risley, P.3    Steckel, D.A.4    Buehler, A.5    von Kegler, S.6
  • 63
    • 33846424939 scopus 로고    scopus 로고
    • Genetic variation in the interleukin-6 gene in relation to risk and outcomes in acute coronary syndrome
    • Mälarstig A., Wallentin L., Siegbahn A. Genetic variation in the interleukin-6 gene in relation to risk and outcomes in acute coronary syndrome. Thromb Res 2007, 119:467-473.
    • (2007) Thromb Res , vol.119 , pp. 467-473
    • Mälarstig, A.1    Wallentin, L.2    Siegbahn, A.3
  • 65
    • 14144253851 scopus 로고    scopus 로고
    • TNF-alpha -308G/A and IL-6 -174 G/C polymorphisms in the Turkish pediatric stroke patients
    • Karahan Z.C., Deda G., Sipahi T., Elhan A.H., Akar N. TNF-alpha -308G/A and IL-6 -174 G/C polymorphisms in the Turkish pediatric stroke patients. Thromb Res 2005, 115:393-398.
    • (2005) Thromb Res , vol.115 , pp. 393-398
    • Karahan, Z.C.1    Deda, G.2    Sipahi, T.3    Elhan, A.H.4    Akar, N.5
  • 66
    • 38849124033 scopus 로고    scopus 로고
    • Interleukin 6 polymorphism corresponds to the number of severely stenosed coronary arteries
    • Myśliwska J., Wieckiewicz J., Hak L., Siebert J., Rogowski J., Szyndler K., et al. Interleukin 6 polymorphism corresponds to the number of severely stenosed coronary arteries. Eur Cytokine Netw 2006, 17:181-188.
    • (2006) Eur Cytokine Netw , vol.17 , pp. 181-188
    • Myśliwska, J.1    Wieckiewicz, J.2    Hak, L.3    Siebert, J.4    Rogowski, J.5    Szyndler, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.