메뉴 건너뛰기




Volumn 98 B, Issue 2, 2011, Pages 290-299

Synthesis, self-assembly, and cytotoxicity of well-defined trimethylated chitosan-O-poly(ε-caprolactone): Effect of chitosan molecular weight

Author keywords

chitosan; cytotoxicity; micelle; modification; polyelectrolyte surfactant complex

Indexed keywords

AQUEOUS MEDIA; AVERAGE DIAMETER; CAPROLACTONE; CATIONIC MICELLES; CHITOSAN COMPLEX; CRITICAL AGGREGATION CONCENTRATION; GRAFTING LEVELS; HOMOGENEOUS CONDITIONS; IMPROVED SOLUBILITY; MODIFICATION; ORGANOSOLUBLE; POLYELECTROLYTE-SURFACTANT COMPLEXES; SPHERICAL MICELLES; TRIMETHYLATION;

EID: 79960095894     PISSN: 15524973     EISSN: 15524981     Source Type: Journal    
DOI: 10.1002/jbm.b.31851     Document Type: Article
Times cited : (8)

References (35)
  • 1
    • 33750136313 scopus 로고    scopus 로고
    • Current state, achievements, and future prospects of polymeric micelles as nanocarriers for drug and gene delivery
    • DOI 10.1016/j.pharmthera.2006.05.006, PII S0163725806000933
    • Nishiyama N, Kazunori K,. Current state, achievements, and future prospects of polymeric micelles as nanocarriers for drug and gene delivery. Pharmacol Therap 2006; 112: 630-648. (Pubitemid 44592613)
    • (2006) Pharmacology and Therapeutics , vol.112 , Issue.3 , pp. 630-648
    • Nishiyama, N.1    Kataoka, K.2
  • 2
    • 0033221068 scopus 로고    scopus 로고
    • Nano-engineering block copolymer aggregates for drug delivery
    • Allen C, Maysinger D, Eisenberg A,. Nano-engineering block copolymer aggregates for drug delivery. Colloids Surf B 1999; 16: 3-27.
    • (1999) Colloids Surf B , vol.16 , pp. 3-27
    • Allen, C.1    Maysinger, D.2    Eisenberg, A.3
  • 3
    • 51049108389 scopus 로고    scopus 로고
    • Preclinical studies to understand nanoparticles interaction with the immune system and its potential effects on nanoparticle biodistribution
    • Dobrovolskaia MA, Aggarwal P, Hall JB, McNeil SE,. Preclinical studies to understand nanoparticles interaction with the immune system and its potential effects on nanoparticle biodistribution. Mol Pharm 2008; 5: 487-495.
    • (2008) Mol Pharm , vol.5 , pp. 487-495
    • Dobrovolskaia, M.A.1    Aggarwal, P.2    Hall, J.B.3    McNeil, S.E.4
  • 4
    • 51049092308 scopus 로고    scopus 로고
    • Factors affecting the clearance and biodistribution of polymeric nanoparticles
    • Alexis F, Pridgen E, Molnar LK, Farokhzad OC,. Factors affecting the clearance and biodistribution of polymeric nanoparticles. Mol Pharm 2008; 5: 505-515.
    • (2008) Mol Pharm , vol.5 , pp. 505-515
    • Alexis, F.1    Pridgen, E.2    Molnar, L.K.3    Farokhzad, O.C.4
  • 5
    • 39749178290 scopus 로고    scopus 로고
    • Surface charge of nanoparticles determines their endocytic and transcytotic pathway in polarized MDCK cells
    • DOI 10.1021/bm700535p
    • Harush-Frenkel O, Rozentur E, Benita S, Altschuler Y,. Surface charge of nanoparticles determines their endocytic and transcytotic pathway in polarized MDCK cells. Biomacromolecules 2008; 9: 435-443. (Pubitemid 351298461)
    • (2008) Biomacromolecules , vol.9 , Issue.2 , pp. 435-443
    • Harush-Frenkel, O.1    Rozentur, E.2    Benita, S.3    Altschuler, Y.4
  • 6
    • 34249820576 scopus 로고    scopus 로고
    • Multifunctional nanocarriers
    • DOI 10.1016/j.addr.2006.09.009, PII S0169409X06001785, Particulate Nanomedicines
    • Torchilin VP,. Multifunctional nanocarriers. Adv Drug Delivery Rev 2006; 58: 1532-1555. (Pubitemid 44822608)
    • (2006) Advanced Drug Delivery Reviews , vol.58 , Issue.14 , pp. 1532-1555
    • Torchilin, V.P.1
  • 7
    • 0037400585 scopus 로고    scopus 로고
    • New micelle-like polymer aggregates made from PEI-PLGA diblock copolymers: Micellar characteristics and cellular uptake
    • DOI 10.1016/S0142-9612(02)00641-5
    • Nam YS, Kang HS, Park JY, Park TG, Han SH, Chang IS,. New micelle-like polymer aggregates made from PEI-PLGA diblock copolymers: Micellar characteristics and cellular uptake. Biomaterials 2003; 24: 2053-2059. (Pubitemid 36298776)
    • (2003) Biomaterials , vol.24 , Issue.12 , pp. 2053-2059
    • Nam, Y.S.1    Kang, H.S.2    Park, J.Y.3    Park, T.G.4    Han, S.-H.5    Chang, I.-S.6
  • 8
    • 55349109645 scopus 로고    scopus 로고
    • Novel amphiphilic degradable poly(ε-caprolactone)-graft-poly(4-vinyl pyridine), poly(ε-caprolactone)-graft-poly(dimethylaminoethyl methacrylate) and water-soluble derivatives
    • Nottelet B, Vert M, Coudane J,. Novel amphiphilic degradable poly(ε-caprolactone)-graft-poly(4-vinyl pyridine), poly(ε- caprolactone)-graft-poly(dimethylaminoethyl methacrylate) and water-soluble derivatives. Macromol Rapid Commun 2008; 29: 743-750.
    • (2008) Macromol Rapid Commun , vol.29 , pp. 743-750
    • Nottelet, B.1    Vert, M.2    Coudane, J.3
  • 9
    • 60549108609 scopus 로고    scopus 로고
    • Complexes of cationic block copolymer micelles with DNA: Histone/DNA complex mimetics
    • Talelli M, Pispas S,. Complexes of cationic block copolymer micelles with DNA: Histone/DNA complex mimetics. Macromol Biosci 2008; 8: 960-967.
    • (2008) Macromol Biosci , vol.8 , pp. 960-967
    • Talelli, M.1    Pispas, S.2
  • 10
    • 0037130190 scopus 로고    scopus 로고
    • Poly(L-lysine)-g-poly(D,L-lactic-co-glycolic acid) micelles for low cytotoxic biodegradable gene delivery carriers
    • DOI 10.1016/S0168-3659(02)00131-1, PII S0168365902001311
    • Jeong JH, Park TG,. Poly(L-lysine)-g-poly(D,L-lactic-co-glycolic acid) micelles for low cytotoxic biodegradable gene delivery carriers. J Control Release 2002; 82: 159-166. (Pubitemid 34775057)
    • (2002) Journal of Controlled Release , vol.82 , Issue.1 , pp. 159-166
    • Jeong, J.H.1    Park, T.G.2
  • 11
    • 33947648022 scopus 로고    scopus 로고
    • Synthesis and characterizationo of cationic micelles self-assembled from a biodegradable copolymer for gene delivery
    • DOI 10.1021/bm061051c
    • Wang Y, Wang LS, Goh SH, Yang YY,. Synthesis and characterization of cationic micelles self-assembled from a biodegradable copolymer for gene delivery. Biomacromolecules 2007; 8: 1028-1037. (Pubitemid 46488488)
    • (2007) Biomacromolecules , vol.8 , Issue.3 , pp. 1028-1037
    • Wang, Y.1    Wang, L.-S.2    Goh, S.-H.3    Yang, Y.-Y.4
  • 12
    • 35248821266 scopus 로고    scopus 로고
    • Tumoral acidic extracellular pH targeting of pH-responsive MPEG-poly(beta-amino ester) block copolymer micelles for cancer therapy
    • DOI 10.1016/j.jconrel.2007.07.012, PII S0168365907003847
    • Ko J, Park K, Kim YS, Kim MS, Han JK, Kim K, Park RW, Kim IS, Song HK, Lee DS, Kwon IC,. Tumoral acidic extracellular pH targeting of pH-responsive mPEG-poly (beta-amino ester) block copolymer micelles for cancer therapy. J Control Release 2007; 123: 109-115. (Pubitemid 47562136)
    • (2007) Journal of Controlled Release , vol.123 , Issue.2 , pp. 109-115
    • Ko, J.1    Park, K.2    Kim, Y.-S.3    Kim, M.S.4    Han, J.K.5    Kim, K.6    Park, R.-W.7    Kim, I.-S.8    Song, H.K.9    Lee, D.S.10    Kwon, I.C.11
  • 14
    • 33845901550 scopus 로고    scopus 로고
    • Self-catalysis of phthaloylchitosan for graft copolymerization of caprolactone with chitosan
    • DOI 10.1002/marc.200600508
    • Liu L, Chen LX, Fang YE,. Self-catalysis of phthaloylchitosan for graft copolymerization of ε-caprolactone with chitosan. Macromol Rapid Commun 2006; 27: 1988-1994. (Pubitemid 46025934)
    • (2006) Macromolecular Rapid Communications , vol.27 , Issue.23 , pp. 1988-1994
    • Liu, L.1    Chen, L.2    Fang, Y.3
  • 15
    • 33646532048 scopus 로고    scopus 로고
    • Crystalline and micellar properties of amphiphilic biodegradable chitooligosaccharide-graft-poly(ε-caprolactone) copolymers
    • Wang CQ, Li GT, Tao SY, Guo RR, Yan Z,. Crystalline and micellar properties of amphiphilic biodegradable chitooligosaccharide-graft-poly(ε- caprolactone) copolymers. Carbohydr Polym 2006; 64: 466-472.
    • (2006) Carbohydr Polym , vol.64 , pp. 466-472
    • Wang, C.Q.1    Li, G.T.2    Tao, S.Y.3    Guo, R.R.4    Yan, Z.5
  • 16
    • 48449097770 scopus 로고    scopus 로고
    • Biocompatible and biodegradable ultrafine fibrillar scaffold materials for tissue engineering by facile grafting of l-lactide onto chitosan
    • Skotak M, Leonov AP, Larsen G, Noriega S, Subramanian, A,. Biocompatible and biodegradable ultrafine fibrillar scaffold materials for tissue engineering by facile grafting of l-lactide onto chitosan. Biomacromolecules 2008; 9: 1902-1908.
    • (2008) Biomacromolecules , vol.9 , pp. 1902-1908
    • Skotak, M.1    Leonov, A.P.2    Larsen, G.3    Noriega, S.4    Subramanian, A.5
  • 17
    • 0036161444 scopus 로고    scopus 로고
    • Chemoselective protection of the amino groups of chitosan by controlled phthaloylation: Facile preparation of a precursor useful for chemical modifications
    • DOI 10.1021/bm0101163
    • Kurita K, Ikeda H, Yoshida Y, Shimojoh M, Harata M,. Chemoselective protection of the amino groups of chitosan by controlled phthaloylation: Facile preparation of a precursor useful for chemical modifications. Biomacromolecules 2002; 3: 1-4. (Pubitemid 34121151)
    • (2002) Biomacromolecules , vol.3 , Issue.1 , pp. 1-4
    • Kurita, K.1    Ikeda, H.2    Yoshida, Y.3    Shimojoh, M.4    Harata, M.5
  • 18
    • 11844285650 scopus 로고    scopus 로고
    • Different ways for grafting ester derivatives of poly(ethylene glycol) onto chitosan: Related characteristics and potential properties
    • DOI 10.1016/j.polymer.2004.11.104, PII S003238610401239X
    • Lebouc F, Dez I, DesbriÃres J, Picton L, Madec PJ,. Different ways for grafting ester derivatives of poly(ethylene glycol) onto chitosan: Related characteristics and potential properties. Polymer 2005; 46: 639-651. (Pubitemid 40091757)
    • (2005) Polymer , vol.46 , Issue.3 , pp. 639-651
    • Lebouc, F.1    Dez, I.2    Desbrieres, J.3    Picton, L.4    Madec, P.-J.5
  • 19
    • 65149090527 scopus 로고    scopus 로고
    • A facile route for regioselective conjugation of organo-soluble polymers onto chitosan
    • Cai GQ, Jiang HL, Tu KH, Wang LQ,. A facile route for regioselective conjugation of organo-soluble polymers onto chitosan. Macromol Biosci 2009; 9: 256-261.
    • (2009) Macromol Biosci , vol.9 , pp. 256-261
    • Cai, G.Q.1    Jiang, H.L.2    Tu, K.H.3    Wang, L.Q.4
  • 20
    • 0035813752 scopus 로고    scopus 로고
    • Oral drug absorption enhancement by chitosan and its derivatives
    • DOI 10.1016/S0169-409X(01)00231-9, PII S0169409X01002319
    • Thanou M, Verhoef JC, Junginger HE,. Oral drug absorption enhancement by chitosan and its derivatives. Adv Drug Delivery Rev 2001; 52: 117-126. (Pubitemid 33079167)
    • (2001) Advanced Drug Delivery Reviews , vol.52 , Issue.2 , pp. 117-126
    • Thanou, M.1    Verhoef, J.C.2    Junginger, H.E.3
  • 21
    • 37349101929 scopus 로고    scopus 로고
    • Gene delivery using chitosan, trimethyl chitosan or polyethylenglycol- graft-trimethyl chitosan block copolymers: Establishment of structure-activity relationships in vitro
    • DOI 10.1016/j.jconrel.2007.10.013, PII S016836590700569X
    • Germershous O, Mao S, Sitterverg J, Bakowsky U, Kissel T,. Gene delivery using chitosan, trimethyl chitosan or polyethylenglycol-graft-trimethyl chitosan block copolymers: Establishment of structure-activity relationships in vitro. J Control Release 2008; 125: 145-154. (Pubitemid 350299611)
    • (2008) Journal of Controlled Release , vol.125 , Issue.2 , pp. 145-154
    • Germershaus, O.1    Mao, S.2    Sitterberg, J.3    Bakowsky, U.4    Kissel, T.5
  • 22
    • 46749090384 scopus 로고    scopus 로고
    • Synthesis, characterization and in vitro biological properties of O-methyl free N,N,N-trimethylated chitosan
    • Verheul RJ, Amidi M, van der Wal S, van Riet E, Jiskoot W, Hennink WE,. Synthesis, characterization and in vitro biological properties of O-methyl free N,N,N-trimethylated chitosan. Biomaterials 2008; 29: 3642-3649.
    • (2008) Biomaterials , vol.29 , pp. 3642-3649
    • Verheul, R.J.1    Amidi, M.2    Van Der Wal, S.3    Van Riet, E.4    Jiskoot, W.5    Hennink, W.E.6
  • 23
    • 0033707596 scopus 로고    scopus 로고
    • Supramolecular polymer materials: Chain extension of telechelic polymers using a reactive hydrogen-bonding synthon
    • Folmer BJB, Sijbesma RP, Versteegen RM, van der Rijt JAJ, Meijer EW,. Supramolecular polymer materials: Chain extension of telechelic polymers using a reactive hydrogen-bonding synthon. Adv Mater 2000; 12: 874-878.
    • (2000) Adv Mater , vol.12 , pp. 874-878
    • Folmer, B.J.B.1    Sijbesma, R.P.2    Versteegen, R.M.3    Van Der Rijt, J.A.J.4    Meijer, E.W.5
  • 24
    • 0037059206 scopus 로고    scopus 로고
    • Incorporation and release of hydrophobic probes in biocompatible polycaprolactone-block-poly(ethylene oxide) micelles: Implications for drug delivery
    • Soo PL, Luo LB, Maysinger D, Eisenberg A,. Incorporation and release of hydrophobic probes in biocompatible polycaprolactone-block-poly(ethylene oxide) micelles: Implications for drug delivery. Langmuir 2002; 18: 9996-10004.
    • (2002) Langmuir , vol.18 , pp. 9996-10004
    • Soo, P.L.1    Luo, L.B.2    Maysinger, D.3    Eisenberg, A.4
  • 25
    • 3543051289 scopus 로고    scopus 로고
    • The depolymerization of chitosan: Effects on physicochemical and biological properties
    • DOI 10.1016/j.ijpharm.2004.05.019, PII S037851730400300X
    • Mao S, Shuai XT, Unger F, Simon M, Bi DZ, Kissel T,. The depolymerization of chitosan: effects on physicochemical and biological properties. Intern J Pharm 2004; 281: 45-54. (Pubitemid 39024262)
    • (2004) International Journal of Pharmaceutics , vol.281 , Issue.1-2 , pp. 45-54
    • Mao, S.1    Shuai, X.2    Unger, F.3    Simon, M.4    Bi, D.5    Kissel, T.6
  • 26
    • 33845980248 scopus 로고    scopus 로고
    • Preparation, characterization, and self-sssembled properties of biodegradable chitosan-poly(L-lactide) hybrid amphiphiles
    • DOI 10.1021/bm060568l
    • Feng H, Dong CM,. Preparation, characterization, and self-assembled properties of biodegradable chitosan-poly(L-lactide) hybrid amphiphiles. Biomacromolecules 2006; 7: 3069-3075. (Pubitemid 46039962)
    • (2006) Biomacromolecules , vol.7 , Issue.11 , pp. 3069-3075
    • Feng, H.1    Dong, C.-M.2
  • 27
    • 66849083442 scopus 로고    scopus 로고
    • Poly[lactic-co-(glycolic acid)]-grafted hyaluronic acid copolymer micelle nanoparticles for target-specific delivery of doxorubicin
    • Lee H, Ahn Chee, Park TG,. Poly[lactic-co-(glycolic acid)]-grafted hyaluronic acid copolymer micelle nanoparticles for target-specific delivery of doxorubicin. Macromol Biosci 2008; 9: 336-342.
    • (2008) Macromol Biosci , vol.9 , pp. 336-342
    • Lee, H.1    Ahn, C.2    Park, T.G.3
  • 28
    • 33646353919 scopus 로고    scopus 로고
    • Preparation of amphiphilic poly(L-lactide)-graft-chondroitin sulfate copolymer self-aggregates and its aggregation behavior
    • Lee CT, Huang CP, Lee YD,. Preparation of amphiphilic poly(L-lactide)-graft-chondroitin sulfate copolymer self-aggregates and its aggregation behavior. Biomacromolecules 2006; 7: 1179-1186.
    • (2006) Biomacromolecules , vol.7 , pp. 1179-1186
    • Lee, C.T.1    Huang, C.P.2    Lee, Y.D.3
  • 29
    • 0346634895 scopus 로고    scopus 로고
    • In vitro cytotoxicity testing of polycations: Influence of polymer structure on cell viability and hemolysis
    • DOI 10.1016/S0142-9612(02)00445-3, PII S0142961202004453
    • Fischer D, Li YX, Ahlemeyer B, Krieglstein J, Kissel T,. In vitro cytotoxicity testing of polycations: Influence of polymer structure on cell viability and hemolysis. Biomaterials 2003; 24: 1121-1131. (Pubitemid 36069121)
    • (2003) Biomaterials , vol.24 , Issue.7 , pp. 1121-1131
    • Fischer, D.1    Li, Y.2    Ahlemeyer, B.3    Krieglstein, J.4    Kissel, T.5
  • 30
    • 20444441841 scopus 로고    scopus 로고
    • Synthesis, characterization and cytotoxicity of poly(ethylene glycol)-graft-trimethyl chitosan block copolymers
    • DOI 10.1016/j.biomaterials.2005.03.036, PII S0142961205002723
    • Mao SR, Shuai XT, Unger F, Wittmar M, Xie XL, Kissel T,. Synthesis, characterization and cytotoxicity of poly(ethylene glycol)-graft-trimethyl chitosan block copolymers. Biomaterials 2005; 26: 6343-6356. (Pubitemid 40828390)
    • (2005) Biomaterials , vol.26 , Issue.32 , pp. 6343-6356
    • Mao, S.1    Shuai, X.2    Unger, F.3    Wittmar, M.4    Xie, X.5    Kissel, T.6
  • 31
    • 0033960143 scopus 로고    scopus 로고
    • Effect of degree of quaternization of N-trimethyl chitosan chloride for enhanced transport of hydrophilic compounds across intestinal Caco-2 cell monolayers
    • DOI 10.1016/S0168-3659(99)00131-5, PII S0168365999001315
    • Thanou M, Kotzé AF, Scharringhausen T, Lueβn HL, De Boer AG, Verhoef JC, Junginger HE,. Effect of degree of quaternization of N-trimethyl chitosan chloride for enhanced transport of hydrophilic compounds across intestinal Caco-2 cell monolayers. J Control Release 2000; 64: 15-25. (Pubitemid 30035304)
    • (2000) Journal of Controlled Release , vol.64 , Issue.1-3 , pp. 15-25
    • Thanou, M.M.1    Kotze, A.F.2    Scharringhausen, T.3    Luessen, H.L.4    De Boer, A.G.5    Verhoef, J.C.6    Junginger, H.E.7
  • 33
    • 0036832895 scopus 로고    scopus 로고
    • The relationship between the absolute molecular weight and the degree of quaternisation of N-trimethyl chitosan chloride
    • DOI 10.1016/S0144-8617(02)00008-5, PII S0144861702000085
    • Snyman D, Hamman JH, Kotzé JS, Rollings JE, Kotzé AF,. The relationship between the absolute molecular weight and the degree of quaternisation of N-trimethyl chitosan chloride. Carbohydr Polym 2002; 50: 145-150. (Pubitemid 34661462)
    • (2002) Carbohydrate Polymers , vol.50 , Issue.2 , pp. 145-150
    • Snyman, D.1    Hamman, J.H.2    Kotze, J.S.3    Rollings, J.E.4    Kotze, A.F.5
  • 34
    • 0142152952 scopus 로고    scopus 로고
    • Methylation of Chitosan with Iodomethane: Effect of Reaction Conditions on Chemoselectivity and Degree of Substitution
    • DOI 10.1002/mabi.200300030
    • Curti E, De Britto D, Campana-Filho SP,. Methylation of chitosan with iodomethane: Effect of reaction conditions on chemoselectivity and degree of substitution. Macromol Biosci 2003; 3: 571-576. (Pubitemid 37309683)
    • (2003) Macromolecular Bioscience , vol.3 , Issue.10 , pp. 571-576
    • Curti, E.1    De Britto, D.2    Campana-Filho, S.P.3
  • 35
    • 37849010028 scopus 로고    scopus 로고
    • Preparation, characterization and aggregation behavior of amphiphilic chitosan derivative having poly (L-lactic acid) side chains
    • Li G, Zhuang YL, Mu Q, Wang MZ, Fang YE,. Preparation, characterization and aggregation behavior of amphiphilic chitosan derivative having poly (L-lactic acid) side chains. Carbohydr Polym 2008; 72: 60-66.
    • (2008) Carbohydr Polym , vol.72 , pp. 60-66
    • Li, G.1    Zhuang, Y.L.2    Mu, Q.3    Wang, M.Z.4    Fang, Y.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.