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Volumn 29, Issue 5, 2011, Pages 400-407

Functional roles of superoxide and hydrogen peroxide generated by mitochondrial DNA mutation in regulating tumorigenicity of HepG2 cells

Author keywords

Hydrogen peroxide; ND6 gene mutation; Respiratory complex I; Superoxide; Tumorigenesis

Indexed keywords

2 CHLORO 1,3 DIBENZOTHIAZOLINECYCLOHEXENE; CYCLOHEXENE DERIVATIVE; HYDROGEN PEROXIDE; MITOCHONDRIAL DNA; NAPHTHOFLUORESCEIN DISULFONATE; NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE SUBUNIT 6; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; SULFONIC ACID DERIVATIVE; SUPEROXIDE; UNCLASSIFIED DRUG;

EID: 79960085670     PISSN: 02636484     EISSN: 10990844     Source Type: Journal    
DOI: 10.1002/cbf.1764     Document Type: Article
Times cited : (11)

References (33)
  • 1
    • 34648813720 scopus 로고    scopus 로고
    • ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis
    • D'Autréaux B, Toledano MB. ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis. Nat Rev Mol Cell Biol 2007; 8: 813-824.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 813-824
    • D'Autréaux, B.1    Toledano, M.B.2
  • 2
    • 57649210205 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations in disease, aging, and neurodegeneration
    • Reeve A, Krishnan K, Turnbull D. Mitochondrial DNA mutations in disease, aging, and neurodegeneration. Ann NY Acad Sci 2008; 1147: 21-29.
    • (2008) Ann NY Acad Sci , vol.1147 , pp. 21-29
    • Reeve, A.1    Krishnan, K.2    Turnbull, D.3
  • 3
    • 34250650151 scopus 로고    scopus 로고
    • Mitochondrial DNA medicine
    • DiMauro S. Mitochondrial DNA medicine. Biosci Rep 2007; 27: 5-9.
    • (2007) Biosci Rep , vol.27 , pp. 5-9
    • DiMauro, S.1
  • 4
    • 13444271415 scopus 로고    scopus 로고
    • Mitochondrial genes in degenerative diseases, cancer and aging
    • Rimoin DL, Connor, JM (eds.). Churchill Livingstone: London
    • Wallace DC, Lott MT. Mitochondrial genes in degenerative diseases, cancer and aging. In Emery and Rimoin's Principles and Practice of Medical Genetics, Rimoin DL, Connor, JM (eds.). Churchill Livingstone: London, 2002; 299-409.
    • (2002) Emery and Rimoin's Principles and Practice of Medical Genetics , pp. 299-409
    • Wallace, D.C.1    Lott, M.T.2
  • 5
    • 0032541401 scopus 로고    scopus 로고
    • The mtDNA-encoded ND6 subunit of mitochondrial NADH dehydrogenase is essential for the assembly of the membrane arm and the respiratory function of the enzyme
    • Bai Y, Attardi G. The mtDNA-encoded ND6 subunit of mitochondrial NADH dehydrogenase is essential for the assembly of the membrane arm and the respiratory function of the enzyme. EMBO J 1998; 17: 4848-4858.
    • (1998) EMBO J , vol.17 , pp. 4848-4858
    • Bai, Y.1    Attardi, G.2
  • 6
    • 0025760073 scopus 로고
    • The respiratory-chain NADH dehydrogenase (Complex I) of mitochondria
    • Weiss H, Friedrich T, Hofhaus G, Preis D. The respiratory-chain NADH dehydrogenase (Complex I) of mitochondria. Eur J Biochem 1991; 197: 563-576.
    • (1991) Eur J Biochem , vol.197 , pp. 563-576
    • Weiss, H.1    Friedrich, T.2    Hofhaus, G.3    Preis, D.4
  • 7
    • 0030030467 scopus 로고    scopus 로고
    • Novel mitochondrial DNA deletion found in a renal cell carcinoma
    • Horton TM, Petros JA, Heddi A, et al. Novel mitochondrial DNA deletion found in a renal cell carcinoma. Genes Chromosom Cancer 1996; 15: 95-101.
    • (1996) Genes Chromosom Cancer , vol.15 , pp. 95-101
    • Horton, T.M.1    Petros, J.A.2    Heddi, A.3
  • 8
    • 0031736203 scopus 로고    scopus 로고
    • Somatic mutations of the mitochondrial genome in human colorectal tumors
    • Polyak K, Li Y, Zhu H, et al. Somatic mutations of the mitochondrial genome in human colorectal tumors. Nat Genet 1998; 20: 291-293.
    • (1998) Nat Genet , vol.20 , pp. 291-293
    • Polyak, K.1    Li, Y.2    Zhu, H.3
  • 9
    • 0037112431 scopus 로고    scopus 로고
    • Extensive somatic mitochondrial mutations in primary prostate cancer using laser capture microdissection
    • Chen JZ, Gokden N, Greene GF, Mukunyadzi P, Kadlubar FF. Extensive somatic mitochondrial mutations in primary prostate cancer using laser capture microdissection. Cancer Res 2002; 62: 6470-6474.
    • (2002) Cancer Res , vol.62 , pp. 6470-6474
    • Chen, J.Z.1    Gokden, N.2    Greene, G.F.3    Mukunyadzi, P.4    Kadlubar, F.F.5
  • 10
    • 43249112094 scopus 로고    scopus 로고
    • ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis
    • Ishikawa K, Takenaga K, Akimoto M, et al. ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis. Science 2008; 320: 661-664.
    • (2008) Science , vol.320 , pp. 661-664
    • Ishikawa, K.1    Takenaga, K.2    Akimoto, M.3
  • 11
    • 64549098628 scopus 로고    scopus 로고
    • A heteroplasmic, not homoplasmic, mitochondrial DNA mutation promotes tumorigenesis via alteration in reactive oxygen species generation and apoptosis
    • Park JS, Sharma LK, Li H, et al. A heteroplasmic, not homoplasmic, mitochondrial DNA mutation promotes tumorigenesis via alteration in reactive oxygen species generation and apoptosis. Hum Mol Genet 2009; 18: 1578-1589.
    • (2009) Hum Mol Genet , vol.18 , pp. 1578-1589
    • Park, J.S.1    Sharma, L.K.2    Li, H.3
  • 12
    • 0037452679 scopus 로고    scopus 로고
    • Electrophile and oxidant damage of mitochondrial DNA leading to rapid evolution of homoplasmic mutations
    • Mambo E, Gao X, Cohen Y, Guo Z, Talalay P, Sidransky D. Electrophile and oxidant damage of mitochondrial DNA leading to rapid evolution of homoplasmic mutations. Proc Natl Acad Sci 2003; 100: 1838-1843.
    • (2003) Proc Natl Acad Sci , vol.100 , pp. 1838-1843
    • Mambo, E.1    Gao, X.2    Cohen, Y.3    Guo, Z.4    Talalay, P.5    Sidransky, D.6
  • 14
    • 22144472961 scopus 로고    scopus 로고
    • Mutation in D-loop region of mitochondrial DNA in gastric cancer and its significance
    • Zhao YB, Yang HY, Zhang XW, Chen GY. Mutation in D-loop region of mitochondrial DNA in gastric cancer and its significance. World J Gastroenterol 2005; 11: 3304-3306.
    • (2005) World J Gastroenterol , vol.11 , pp. 3304-3306
    • Zhao, Y.B.1    Yang, H.Y.2    Zhang, X.W.3    Chen, G.Y.4
  • 16
    • 19944428919 scopus 로고    scopus 로고
    • A design of fluorescent probes for superoxide based on a nonredox mechanism
    • Maeda H, Yamamoto K, Nomura Y, et al. A design of fluorescent probes for superoxide based on a nonredox mechanism. J Am Chem Soc 2005; 127: 68-69.
    • (2005) J Am Chem Soc , vol.127 , pp. 68-69
    • Maeda, H.1    Yamamoto, K.2    Nomura, Y.3
  • 17
    • 34250327419 scopus 로고    scopus 로고
    • Design of a phosphinate-based fluorescent probe for superoxide detection in mouse peritoneal macrophages
    • Xu K, Liu X, Tang B, Yang G, Yang Y, An L. Design of a phosphinate-based fluorescent probe for superoxide detection in mouse peritoneal macrophages. Chemistry 2007; 13: 1411-1416.
    • (2007) Chemistry , vol.13 , pp. 1411-1416
    • Xu, K.1    Liu, X.2    Tang, B.3    Yang, G.4    Yang, Y.5    An, L.6
  • 18
    • 0035800889 scopus 로고    scopus 로고
    • Methods of detection of vascular reactive species nitric oxide, superoxide, hydrogen peroxide, and peroxynitrite
    • Tarpey MM, Fridovich I. Methods of detection of vascular reactive species nitric oxide, superoxide, hydrogen peroxide, and peroxynitrite. Circ Res. 2001; 89: 224-236.
    • (2001) Circ Res , vol.89 , pp. 224-236
    • Tarpey, M.M.1    Fridovich, I.2
  • 19
    • 0032211437 scopus 로고    scopus 로고
    • Critical evaluation of the use of hydroethidine as a measure of superoxide anion radical
    • Benov L, Sztejnberg L, Fridovich I. Critical evaluation of the use of hydroethidine as a measure of superoxide anion radical. Free Radical Biol Med 1998; 25: 826-831.
    • (1998) Free Radical Biol Med , vol.25 , pp. 826-831
    • Benov, L.1    Sztejnberg, L.2    Fridovich, I.3
  • 20
    • 77950515980 scopus 로고    scopus 로고
    • Hydroethidine- and MitoSOX-derived red fluorescence is not a reliable indicator of intracellular superoxide formation: another inconvenient truth
    • Zielonkaa J, Kalyanaraman B. Hydroethidine- and MitoSOX-derived red fluorescence is not a reliable indicator of intracellular superoxide formation: another inconvenient truth. Free Radical Biol Med 2010; 48: 983-1001.
    • (2010) Free Radical Biol Med , vol.48 , pp. 983-1001
    • Zielonkaa, J.1    Kalyanaraman, B.2
  • 21
    • 29744448959 scopus 로고    scopus 로고
    • Strong red fluorescent probes suitable for detecting hydrogen peroxide generated by mice peritoneal macrophages
    • Xu K, Tang B, Huang H, et al. Strong red fluorescent probes suitable for detecting hydrogen peroxide generated by mice peritoneal macrophages. Chem Comm 2005; 48: 5974-5976.
    • (2005) Chem Comm , vol.48 , pp. 5974-5976
    • Xu, K.1    Tang, B.2    Huang, H.3
  • 24
    • 33746329868 scopus 로고    scopus 로고
    • Energy converting NADH: quinone oxidoreductase (complex I)
    • Brandt U. Energy converting NADH: quinone oxidoreductase (complex I). Annu Rev Biochem 2006; 75: 69-92.
    • (2006) Annu Rev Biochem , vol.75 , pp. 69-92
    • Brandt, U.1
  • 25
    • 3442902484 scopus 로고    scopus 로고
    • Effect of N-acetyl cysteine on oxidative DNA damage and the frequency of DNA deletions in atm-deficient mice
    • Reliene R, Fischer E, Schiestl RH. Effect of N-acetyl cysteine on oxidative DNA damage and the frequency of DNA deletions in atm-deficient mice. Cancer Res 2004; 64: 5148-5153.
    • (2004) Cancer Res , vol.64 , pp. 5148-5153
    • Reliene, R.1    Fischer, E.2    Schiestl, R.H.3
  • 26
    • 28644447272 scopus 로고    scopus 로고
    • The antioxidant function of the p53 tumor suppressor
    • Sablina AA, Budanov AV, Ilyinskaya GV, et al. The antioxidant function of the p53 tumor suppressor. Nat Med 2005; 11: 1306-1313.
    • (2005) Nat Med , vol.11 , pp. 1306-1313
    • Sablina, A.A.1    Budanov, A.V.2    Ilyinskaya, G.V.3
  • 27
    • 0242319858 scopus 로고    scopus 로고
    • Antioxidant agents are effective in inducing lymphocyte progression through cell cycle in advanced cancer patients: assessment of the most important laboratory indexes of cachexia and oxidative stress
    • Mantovani G, Macciò A, Madeddu C, et al. Antioxidant agents are effective in inducing lymphocyte progression through cell cycle in advanced cancer patients: assessment of the most important laboratory indexes of cachexia and oxidative stress. J Mol Med 2003; 81: 664-673.
    • (2003) J Mol Med , vol.81 , pp. 664-673
    • Mantovani, G.1    Macciò, A.2    Madeddu, C.3
  • 28
    • 0035937771 scopus 로고    scopus 로고
    • 2 by catalase inhibits the proliferation of HER-2/Neutransformed rat-1 fibroblasts through the induction of a stress response
    • 2 by catalase inhibits the proliferation of HER-2/Neutransformed rat-1 fibroblasts through the induction of a stress response. J Biol Chem 2000; 276: 9558-9564.
    • (2000) J Biol Chem , vol.276 , pp. 9558-9564
    • Preston, T.J.1    Muller, W.J.2    Singh, G.3
  • 29
    • 33947250714 scopus 로고    scopus 로고
    • Selective detection of superoxide anion radicals generated from macrophages by using a novel fluorescent probe
    • Gao JJ, Xu Kh, Tang B, Yin LL, Yang GW, An LG. Selective detection of superoxide anion radicals generated from macrophages by using a novel fluorescent probe. FEBS J 2007; 274: 1725-1733.
    • (2007) FEBS J , vol.274 , pp. 1725-1733
    • Gao, J.J.1    Xu, K.2    Tang, B.3    Yin, L.L.4    Yang, G.W.5    An, L.G.6
  • 30
    • 34548148201 scopus 로고    scopus 로고
    • Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals?
    • Giorgio M, Trinei M, Migliaccio E, Pelicci PG. Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals? Nat Rev Mol Cell Biol 2007; 8: 722-728.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 722-728
    • Giorgio, M.1    Trinei, M.2    Migliaccio, E.3    Pelicci, P.G.4
  • 31
    • 75749123115 scopus 로고    scopus 로고
    • Orchestrating redox signaling networks through regulatory cysteine switches
    • Paulsen CE, Carroll KS. Orchestrating redox signaling networks through regulatory cysteine switches. ACS Chem Biol 2010; 1: 47-62.
    • (2010) ACS Chem Biol , vol.1 , pp. 47-62
    • Paulsen, C.E.1    Carroll, K.S.2
  • 33
    • 67649255876 scopus 로고    scopus 로고
    • A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish
    • Niethammer P, Grabher C, Look AT, Mitchison TJ. A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish. Nature 2009; 459: 996-999.
    • (2009) Nature , vol.459 , pp. 996-999
    • Niethammer, P.1    Grabher, C.2    Look, A.T.3    Mitchison, T.J.4


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