Targeting Phosphatidylcholine-Specific Phospholipase C for Atherogenesis Therapy

Trends in Cardiovascular Medicine

Volumn 20, Issue 5, 2010, Pages 172-176

  Li, HaiYing ^a   Zhang, Lu ^a   Yin, DeLing ^b   Zhang, Yun ^c   Miao, JunYing ^a  

^a SHANDONG UNIVERSITY   (China)

^b East Tennessee State University   (United States)

^c SHANDONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHOLIPASE C; PHOSPHOLIPASE C INHIBITOR;

ATHEROGENESIS; ATHEROSCLEROSIS; ENDOTHELIAL DYSFUNCTION; ENZYME ANALYSIS; HUMAN; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; REVIEW;

ATHEROSCLEROSIS; HUMANS; MOLECULAR TARGETED THERAPY; TYPE C PHOSPHOLIPASES;

EID: 79960081490     PISSN: 10501738     EISSN: 18732615     Source Type: Journal    
DOI: 10.1016/j.tcm.2011.02.002     Document Type: Review

References (39)

1. Baggiolini M., Dewald B., Moser B. Human chemokines: An update. Annu Rev Immunol 1997, 15:675-705.
2. Cheng Y., Zhao Q., Liu X., et al. Phosphatidylcholine-specific phospholipase C, p53 and ROS in the association of apoptosis and senescence in vascular endothelial cells. FEBS Lett 2006, 580:4911-4915.
3. Dong Z., Wang L., Xu J., et al. Promotion of autophagy and inhibition of apoptosis by low concentrations of cadmium in vascular endothelial cells. Toxicol In Vitro 2009, 23:105-110.
4. Du C., Zhao Q., Araki S., et al. Apoptosis mediated by phosphatidylcholine-specific phospholipase C is associated with cAMP, p53 level, and cell-cycle distribution in vascular endothelial cells. Endothelium 2003, 10:141-147.
5. Fantuzzi L., Spadaro F., Purificato C., et al. Phosphatidylcholine-specific phospholipase C activation is required for CCR5-dependent, NF-kB-driven CCL2 secretion elicited in response to HIV-1 gp120 in human primary macrophages. Blood 2008, 111:3355-3363.
6. Fenton M.J., Golenbock D.T. LPS-binding proteins and receptors. J Leukoc Biol 1998, 64:25-32.
7. Fuster V., Badimon L., Badimon J.J., Chesebro J.H. The pathogenesis of coronary artery disease and the acute coronary syndromes (1). N Engl J Med 1992, 326:242-250.
8. Goebeler M., Gillitzer R., Kilian K., et al. Multiple signaling pathways regulate NF-kappaB-dependent transcription of the monocyte chemoattractant protein-1 gene in primary endothelial cells. Blood 2001, 97:46-55.
9. Gonzalez-Bulnes P., Gonzalez-Roura A., Canals D., et al. 2-Aminohydroxamic acid derivatives as inhibitors of Bacillus cereus phosphatidylcholine preferred phospholipase C PC-PLC(Bc). Bioorg Med Chem 2010, 18:8549-8555.
10. Horstmeyer A., Licht C., Scherr G., et al. Signalling and regulation of collagen I synthesis by ET-1 and TGF-beta1. FEBS J 2005, 272:6297-6309.
11. Kiss Z., Tomono M. Compound D609 inhibits phorbol ester-stimulated phospholipase D activity and phospholipase C-mediated phosphatidylethanolamine hydrolysis. Biochim Biophys Acta 1995, 1259:105-108.
12. Krunkosky T.M., Fischer B.M., Martin L.D., et al. Effects of TNF-alpha on expression of ICAM-1 in human airway epithelial cells in vitro: Signaling pathways controlling surface and gene expression. Am J Respir Cell Mol Biol 2000, 22:685-692.
13. Li D., Liu L., Chen H., et al. LOX-1 mediates oxidized low-density lipoprotein-induced expression of matrix metalloproteinases in human coronary artery endothelial cells. Circulation 2003, 107:612-617.
14. Liu X., Yin D., Zhang Y., et al. Vascular endothelial cell senescence mediated by integrin beta4 in vitro. FEBS Lett 2007, 581:5337-5342.
15. Mateos M.V., Uranga R.M., Salvador G.A., Giusto N.M. Coexistence of phosphatidylcholine-specific phospholipase C and phospholipase D activities in rat cerebral cortex synaptosomes. Lipids 2006, 41:273-280.
16. Mehta J.L., Sanada N., Hu C.P., et al. Deletion of LOX-1 reduces atherogenesis in LDLR knockout mice fed high cholesterol diet. Circ Res 2007, 100:1634-1642.
17. Miao J.Y., Kaji K., Hayashi H., Araki S. Suppression of apoptosis by inhibition of phosphatidylcholine-specific phospholipase C in vascular endothelial cells. Endothelium 1997, 5:231-239.
18. Miao J.Y., Zhao B.X., Li H.H., et al. Effect of safrole oxide on vascular endothelial cell growth and apoptosis induced by deprivation of fibroblast growth factor. Acta Pharmacol Sin 2002, 23:323-326.
19. Monick M.M., Carter A.B., Gudmundsson G., et al. A phosphatidylcholine-specific phospholipase C regulates activation of p42/44 mitogen-activated protein kinases in lipopolysaccharide-stimulated human alveolar macrophages. J Immunol 1999, 162:3005-3012.
20. Paris L., Cecchetti S., Spadaro F., et al. Inhibition of phosphatidylcholine-specific phospholipase C downregulates HER2 overexpression on plasma membrane of breast cancer cells. Breast Cancer Res 2010, 12:R27.
21. Pober J.S., Min W., Bradley J.R. Mechanisms of endothelial dysfunction, injury, and death. Annu Rev Pathol 2009, 4:71-95.
22. Podo F., Ferretti A., Knijn A., et al. Detection of phosphatidylcholine-specific phospholipase C in NIH-3T3 fibroblasts and their H-ras transformants: NMR and immunochemical studies. Anticancer Res 1996, 16:1399-1412.
23. Pomerantsev A.P., Kalnin K.V., Osorio M., Leppla S.H. Phosphatidylcholine-specific phospholipase C and sphingomyelinase activities in bacteria of the Bacillus cereus group. Infect Immun 2003, 71:6591-6606.
24. Ramoni C., Spadaro F., Barletta B., et al. Phosphatidylcholine-specific phospholipase C in mitogen-stimulated fibroblasts. Exp Cell Res 2004, 299:370-382.
25. Ramoni C., Spadaro F., Menegon M., Podo F. Cellular localization and functional role of phosphatidylcholine-specific phospholipase C in NK cells. J Immunol 2001, 167:2642-2650.
26. Roth G.A., Moser B., Roth-Walter F., et al. Infection with a periodontal pathogen increases mononuclear cell adhesion to human aortic endothelial cells. Atherosclerosis 2007, 190:271-281.
27. Sheikhnejad R.G., Srivastava P.N. Isolation and properties of a phosphatidylcholine-specific phospholipase C from bull seminal plasma. J Biol Chem 1986, 261:7544-7549.
28. Spadaro F., Ramoni C., Mezzanzanica D., et al. Phosphatidylcholine-specific phospholipase C activation in epithelial ovarian cancer cells. Cancer Res 2008, 68:6541-6549.
29. Tsai C.C., Kai J.I., Huang W.C., et al. Glycogen synthase kinase-3beta facilitates IFN-gamma-induced STAT1 activation by regulating Src homology-2 domain-containing phosphatase 2. J Immunol 2009, 183:856-864.
30. Valledor A.F., Comalada M., Xaus J., Celada A. The differential time-course of extracellular-regulated kinase activity correlates with the macrophage response toward proliferation or activation. J Biol Chem 2000, 275:7403-7409.
31. Volwerk J.J., Wetherwax P.B., Evans L.M., et al. Phosphatidylinositol-specific phospholipase C from Bacillus cereus: Improved purification, amino acid composition, and amino-terminal sequence. J Cell Biochem 1989, 39:315-325.
32. Weber C., Erl W., Pietsch A., et al. Docosahexaenoic acid selectively attenuates induction of vascular cell adhesion molecule-1 and subsequent monocytic cell adhesion to human endothelial cells stimulated by tumor necrosis factor-alpha. Arterioscler Thromb Vasc Biol 1995, 15:622-628.
33. Wolf R.A., Gross R.W. Identification of neutral active phospholipase C which hydrolyzes choline glycerophospholipids and plasmalogen selective phospholipase A2 in canine myocardium. J Biol Chem 1985, 260:7295-7303.
34. Xuan H., Zhu R., Li Y. Inhibitory effect of Chinese propolis on phosphatidylcholine-specific phospholipase C activity in vascular endothelial cells. Evid Based Complement Alternat Med 2011, 2011:985278.
35. Zetter B.R., Johnson L.K., Shuman M.A., Gospodarowicz D. The isolation of vascular endothelial cell lines with altered cell surface and platelet-binding properties. Cell 1978, 14:501-509.
36. Zhang L., Li H.Y., Li H., et al. Lipopolysaccharide activated phosphatidylcholine-specific phospholipase C and induced IL-8 and MCP-1 production in vascular endothelial cells. J Cell Physiol 2011, 226:1694-1701.
37. Zhang L., Zhao J., Su L., et al. D609 inhibits progression of preexisting atheroma and promotes lesion stability in apolipoprotein e-/- mice: A role of phosphatidylcholine-specific phospholipase in atherosclerosis. Arterioscler Thromb Vasc Biol 2010, 30:411-418.
38. Zhao J., Miao J., Zhao B., Zhang S. Upregulating of Fas, integrin beta4 and P53 and depressing of PC-PLC activity and ROS level in VEC apoptosis by safrole oxide. FEBS Lett 2005, 579:5809-5813.
39. Zhao Q., Araki S., Zhang S., Miao J. Rattlesnake venom induces apoptosis by stimulating PC-PLC and upregulating the expression of integrin beta4, P53 in vascular endothelial cells. Toxicon 2004, 44:161-168.