Influence of kinetics of drug binding on EGFR signaling: A comparative study of three EGFR signaling pathway models

Proteins: Structure, Function and Bioinformatics

Volumn 79, Issue 8, 2011, Pages 2491-2504

  Bairy, Sneha ^a   Wong, Chung F ^a  

^a UNIVERSITY OF MISSOURI ST LOUIS   (United States)

Author keywords

COPASI; Drug binding kinetics; Epidermal growth factor receptor signaling; Pathway modeling; Protein kinases

Indexed keywords

DRUG; EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE; RAF PROTEIN; RAS PROTEIN;

ARTICLE; CELL LINE; CELL PROLIFERATION; CELL SURFACE; CONTROLLED STUDY; DRUG BINDING; DRUG RECEPTOR BINDING; DRUG TARGETING; FEMALE; HUMAN; HUMAN CELL; MODEL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SIMULATION;

COMPUTER SIMULATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; KINETICS; PHARMACEUTICAL PREPARATIONS; PROTEIN BINDING; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 79960079726     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.23072     Document Type: Article

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