메뉴 건너뛰기




Volumn 366, Issue 1575, 2011, Pages 2307-2311

Using stem cells to study and possibly treat type 1 diabetes

Author keywords

Chemical screening; Diabetes; Juvenile diabetes; Pancreas; Stem cells; Type 1 diabetes

Indexed keywords

CYTOLOGY; DIABETES; JUVENILE; MOLECULAR ANALYSIS; PHENOTYPE; THEORETICAL STUDY;

EID: 79960038146     PISSN: 09628436     EISSN: 14712970     Source Type: Journal    
DOI: 10.1098/rstb.2011.0019     Document Type: Review
Times cited : (23)

References (18)
  • 1
    • 34347341846 scopus 로고    scopus 로고
    • Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
    • (doi:10.1038/ng2068)
    • Todd, J. A. et al. 2007 Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nat. Genet. 39, 857-864. (doi:10.1038/ng2068)
    • (2007) Nat. Genet. , vol.39 , pp. 857-864
    • Todd, J.A.1
  • 2
    • 0033358374 scopus 로고    scopus 로고
    • The predisposition to type 1 diabetes linked to the human leukocyte antigen complex includes at least one non-class II gene
    • (doi:10.1086/302283)
    • Benedicte, A. L. et al. 1999 The predisposition to type 1 diabetes linked to the human leukocyte antigen complex includes at least one non-class II gene. Am. J. Hum. Genet. 64, 793-800. (doi:10.1086/302283)
    • (1999) Am. J. Hum. Genet. , vol.64 , pp. 793-800
    • Benedicte, A.L.1
  • 3
    • 78751662679 scopus 로고    scopus 로고
    • Type 1 diabetes: Etiology, immunology and therapeutic strategies
    • (doi:10.1152/physrev.00003.2010)
    • Van Belle, T. L., Coppieters, K. T. & Von Herrath, M. G. 2011 Type 1 diabetes: etiology, immunology and therapeutic strategies. Physiol. Rev. 91, 79-118. (doi:10.1152/physrev.00003.2010)
    • (2011) Physiol. Rev. , vol.91 , pp. 79-118
    • van Belle, T.L.1    Coppieters, K.T.2    von Herrath, M.G.3
  • 4
    • 33644750399 scopus 로고    scopus 로고
    • Autoantibodies in diabetes
    • (doi:10.2337/diabetes.54.suppl_2.S52)
    • Pihoker, C., Gilliam, L. K., Hampe, C. S. & Lernmark, A. 2005 Autoantibodies in diabetes. Diabetes 54(Suppl. 2), S52-S561. (doi:10.2337/diabetes.54.suppl_2.S52)
    • (2005) Diabetes , vol.54 , Issue.SUPPL. 2
    • Pihoker, C.1    Gilliam, L.K.2    Hampe, C.S.3    Lernmark, A.4
  • 5
    • 0029026658 scopus 로고
    • Islet infiltrating lympocytes from prediabetic NOD mice rapidly transfer diabetes to NOD-scid/scid mice
    • (doi:10.2337/diabetes.44.5.550)
    • Rohane, P. W., Shimada, A., Kim, D. T., Edwards, C. T., Charlton, B., Shultz, L. D. & Fathman, C. G. 1995 Islet infiltrating lympocytes from prediabetic NOD mice rapidly transfer diabetes to NOD-scid/scid mice. Diabetes 44, 550-554. (doi:10.2337/diabetes.44.5.550)
    • (1995) Diabetes , vol.44 , pp. 550-554
    • Rohane, P.W.1    Shimada, A.2    Kim, D.T.3    Edwards, C.T.4    Charlton, B.5    Shultz, L.D.6    Fathman, C.G.7
  • 6
    • 78049423506 scopus 로고    scopus 로고
    • An update on the use of NOD mice to study autoimmune (type 1) diabetes
    • (doi:10.1586/eci.10.68)
    • Chaparro, R. J. & DiLorenzo, T. P. 2010 An update on the use of NOD mice to study autoimmune (type 1) diabetes. Expert Rev. Clin. Immunol. 6, 939-955. (doi:10.1586/eci.10.68)
    • (2010) Expert Rev. Clin. Immunol. , vol.6 , pp. 939-955
    • Chaparro, R.J.1    Dilorenzo, T.P.2
  • 7
    • 58449085511 scopus 로고    scopus 로고
    • Animal models of human type 1 diabetes
    • (doi:10.1038/ni0209-129)
    • von Herrath, M. & Nepom, G. 2009 Animal models of human type 1 diabetes. Nat. Immunol. 10, 129-132. (doi:10.1038/ni0209-129)
    • (2009) Nat. Immunol. , vol.10 , pp. 129-132
    • von Herrath, M.1    Nepom, G.2
  • 8
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • (doi:10.1016/j.cell.2007.11.019)
    • Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K. & Yamanaka, S. 2007 Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131, 861-872. (doi:10.1016/j.cell.2007.11.019)
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6    Yamanaka, S.7
  • 9
    • 77958536106 scopus 로고    scopus 로고
    • Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA
    • (doi:10.1016/j.stem.2010.08.012)
    • Warren, L. et al. 2010 Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 7, 618-630. (doi:10.1016/j.stem.2010.08.012)
    • (2010) Cell Stem Cell , vol.7 , pp. 618-630
    • Warren, L.1
  • 10
    • 58149262961 scopus 로고    scopus 로고
    • Transcriptional dynamics of endodermal organ formation
    • (doi:10.1002/dvdy.21810)
    • Sherwood, R. I., Chen, T. Y. & Melton, D. A. 2009 Transcriptional dynamics of endodermal organ formation. Dev. Dyn. 238, 29-42. (doi:10.1002/dvdy.21810)
    • (2009) Dev. Dyn. , vol.238 , pp. 29-42
    • Sherwood, R.I.1    Chen, T.Y.2    Melton, D.A.3
  • 11
    • 33745532385 scopus 로고    scopus 로고
    • Formation of a functional thymus initiated by a postnatal epithelial progenitor cell
    • (doi:10.1038/ nature04850)
    • Bleul, C. C., Corbeaux, T., Reuter, A., Fisch, P., Mönting, J. S. & Boehm, T. 2006 Formation of a functional thymus initiated by a postnatal epithelial progenitor cell. Nature 441, 992-996. (doi:10.1038/ nature04850)
    • (2006) Nature , vol.441 , pp. 992-996
    • Bleul, C.C.1    Corbeaux, T.2    Reuter, A.3    Fisch, P.4    Mönting, J.S.5    Boehm, T.6
  • 12
    • 77749326488 scopus 로고    scopus 로고
    • Humanized mouse models to study human diseases
    • (doi:10.1097/MED.0b013e328337282f)
    • Brehm, M. A., Shultz, L. D. & Greiner, D. L. 2010 Humanized mouse models to study human diseases. Curr. Opin. Endocrinol. Diabetes Obes. 17, 120-125. (doi:10.1097/MED.0b013e328337282f)
    • (2010) Curr. Opin. Endocrinol. Diabetes Obes. , vol.17 , pp. 120-125
    • Brehm, M.A.1    Shultz, L.D.2    Greiner, D.L.3
  • 13
    • 2342510386 scopus 로고    scopus 로고
    • Adult pancreatic b cells are formed by selfduplication rather than stem-cell differentiation
    • (doi:10.1038/nature02520)
    • Dor, Y., Brown, J., Martinez, O. I. & Melton, D. A. 2004 Adult pancreatic b cells are formed by selfduplication rather than stem-cell differentiation. Nature 429, 41-46. (doi:10.1038/nature02520)
    • (2004) Nature , vol.429 , pp. 41-46
    • Dor, Y.1    Brown, J.2    Martinez, O.I.3    Melton, D.A.4
  • 14
    • 53349178722 scopus 로고    scopus 로고
    • In vivo reprogramming of adult pancreatic exocrine cells to b-cells
    • (doi:10.1038/nature07314)
    • Zhou, Q., Brown, J., Kanarek, A., Rajagopal, J. & Melton, D. A. 2008 In vivo reprogramming of adult pancreatic exocrine cells to b-cells. Nature 455, 627-632. (doi:10.1038/nature07314)
    • (2008) Nature , vol.455 , pp. 627-632
    • Zhou, Q.1    Brown, J.2    Kanarek, A.3    Rajagopal, J.4    Melton, D.A.5
  • 15
    • 77951611220 scopus 로고    scopus 로고
    • Conversion of adult pancreatic a cells to b cells after extreme b cell loss
    • (doi:10.1038/nature08894)
    • Thorel, F., Népote, V., Avril, I., Kohno, K., Desgraz, R., Chera, S. & Herrera, P. L. 2010 Conversion of adult pancreatic a cells to b cells after extreme b cell loss. Nature 464, 1149-1154. (doi:10.1038/nature08894)
    • (2010) Nature , vol.464 , pp. 1149-1154
    • Thorel, F.1    Népote, V.2    Avril, I.3    Kohno, K.4    Desgraz, R.5    Chera, S.6    Herrera, P.L.7
  • 16
    • 62949210744 scopus 로고    scopus 로고
    • Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells
    • (doi:10.1016/j.stem.2009.01.014)
    • Borowiak, M., Maehr, R., Chen, S., Chen, A.E., Tang, W., Fox, J. L., Schreiber, S. L. & Melton, D. A. 2009 Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells. Cell Stem Cell 4, 348-358. (doi:10.1016/j.stem.2009.01.014)
    • (2009) Cell Stem Cell , vol.4 , pp. 348-358
    • Borowiak, M.1    Maehr, R.2    Chen, S.3    Chen, A.E.4    Tang, W.5    Fox, J.L.6    Schreiber, S.L.7    Melton, D.A.8
  • 17
    • 62649138086 scopus 로고    scopus 로고
    • A small molecule that directs differentiation of human ESCs into the pancreatic lineage
    • (doi:10.1038/ nchembio.154)
    • Chen, S. et al. 2009 A small molecule that directs differentiation of human ESCs into the pancreatic lineage. Nat. Chem. Biol. 5, 258-265. (doi:10.1038/ nchembio.154)
    • (2009) Nat. Chem. Biol. , vol.5 , pp. 258-265
    • Chen, S.1
  • 18
    • 41849151748 scopus 로고    scopus 로고
    • Pancreatic endoderm derived from human embryonic stem cells generates glucoseresponsive insulin-secreting cells in vivo
    • (doi:10.1038/nbt1393)
    • Kroon, E. et al. 2008 Pancreatic endoderm derived from human embryonic stem cells generates glucoseresponsive insulin-secreting cells in vivo. Nat. Biotechnol. 26, 443-452. (doi:10.1038/nbt1393)
    • (2008) Nat. Biotechnol. , vol.26 , pp. 443-452
    • Kroon, E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.