메뉴 건너뛰기




Volumn 6, Issue 2, 2011, Pages 121-136

Management of painful symptoms with duloxetine: A review of the efficacy in pre-clinical and clinical studies

Author keywords

Anxiety; Depression; Diabetic neuropathic pain; Duloxetine; Fibromyalgia; Pain

Indexed keywords

ANTIARRHYTHMIC AGENT; ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; DULOXETINE; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE; PLACEBO;

EID: 79960027669     PISSN: 15748855     EISSN: 10657630     Source Type: Journal    
DOI: 10.2174/157488511795304903     Document Type: Article
Times cited : (7)

References (94)
  • 2
    • 0035256911 scopus 로고    scopus 로고
    • The molecular dynamics of pain control
    • Hunt SP, Mantyh PW. The molecular dynamics of pain control. Nat Rev Neurosci 2001; 2: 83-91.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 83-91
    • Hunt, S.P.1    Mantyh, P.W.2
  • 3
    • 0036844495 scopus 로고    scopus 로고
    • Descending modulation in persistent pain: An update
    • Ren K, Dubner R. Descending modulation in persistent pain: an update. Pain 2002; 100: 1-6.
    • (2002) Pain , vol.100 , pp. 1-6
    • Ren, K.1    Dubner, R.2
  • 5
    • 0036277865 scopus 로고    scopus 로고
    • Descending control of pain
    • Millan MJ. Descending control of pain. Prog Neurobiol 2002; 66: 355-474.
    • (2002) Prog Neurobiol , vol.66 , pp. 355-474
    • Millan, M.J.1
  • 6
    • 0142165209 scopus 로고    scopus 로고
    • Is noradrenalin a significant factor in the analgesic effect of antidepressants?
    • Jasmin L, Tien D, Janni G, Ohara PT. Is noradrenalin a significant factor in the analgesic effect of antidepressants? Pain 2003; 106(1-2): 3-8.
    • (2003) Pain , vol.106 , Issue.1-2 , pp. 3-8
    • Jasmin, L.1    Tien, D.2    Janni, G.3    Ohara, P.T.4
  • 7
    • 33750630238 scopus 로고    scopus 로고
    • Noradrenergic pain modulation
    • Pertovaara A. Noradrenergic pain modulation. Prog Neurobiol 2006; 80(2): 53-83.
    • (2006) Prog Neurobiol , vol.80 , Issue.2 , pp. 53-83
    • Pertovaara, A.1
  • 8
    • 33847326928 scopus 로고    scopus 로고
    • Gaeta R. The role of adrenergic receptors and pain: The good, the bad, and the unknown
    • Carroll I, Mackey S, Gaeta R. The role of adrenergic receptors and pain: The good, the bad, and the unknown. Semin Anesthesia Periop Med Pain 2007; 26: 17-21.
    • (2007) Semin Anesthesia Periop Med Pain , vol.26 , pp. 17-21
    • Carroll, I.1    Mackey, S.2
  • 9
    • 63649150808 scopus 로고    scopus 로고
    • Noradrenergic neurons in the locus coeruleus contribute to neuropathic pain
    • Brightwell JJ, Taylor BK. Noradrenergic neurons in the locus coeruleus contribute to neuropathic pain. Neuroscience 2009; 160: 174-85.
    • (2009) Neuroscience , vol.160 , pp. 174-185
    • Brightwell, J.J.1    Taylor, B.K.2
  • 10
    • 0036711243 scopus 로고    scopus 로고
    • Reduced basal release of serotonin from the ventrobasal thalamus of the rat model of neuropathic pain
    • Goettl VM, Huang Y, Hackshaw KV, Stephens RL Jr. Reduced basal release of serotonin from the ventrobasal thalamus of the rat model of neuropathic pain. Pain 2002; 99(1): 359-66.
    • (2002) Pain , vol.99 , Issue.1 , pp. 359-366
    • Goettl, V.M.1    Huang, Y.2    Hackshaw, K.V.3    Stephens Jr., R.L.4
  • 11
    • 0036282045 scopus 로고    scopus 로고
    • Hulsebosch CE. Changes in serotonin, serotonin transport expression, and serotonin denervation supersensitivity: Involvement in chronic central pain after spinal hemisection in the rat
    • Hains BC, Everhart AW, Fullwood SD, Hulsebosch CE. Changes in serotonin, serotonin transport expression, and serotonin denervation supersensitivity: Involvement in chronic central pain after spinal hemisection in the rat. Exper Neurol 2002; 175: 347-62.
    • (2002) Exper Neurol , vol.175 , pp. 347-362
    • Hains, B.C.1    Everhart, A.W.2    Fullwood, S.D.3
  • 12
    • 7644219835 scopus 로고    scopus 로고
    • Bad news from the brain: Descending 5-HT pathways that control spinal pain processing
    • Suzuki R, Rygh LJ, Dickenson AH. Bad news from the brain: descending 5-HT pathways that control spinal pain processing. Trends Pharmacol Sci 2004; 25(12): 613-17.
    • (2004) Trends Pharmacol Sci , vol.25 , Issue.12 , pp. 613-617
    • Suzuki, R.1    Rygh, L.J.2    Dickenson, A.H.3
  • 13
    • 44649112692 scopus 로고    scopus 로고
    • Reduced thermal hyperalgesia and enhanced peripheral nerve injury after hind paw inflammation in mice lacking the serotonin-transporter
    • Palm F, Mossner R, Chen Y, et al. Reduced thermal hyperalgesia and enhanced peripheral nerve injury after hind paw inflammation in mice lacking the serotonin-transporter. Eur J Pain 2008; 12: 790-7.
    • (2008) Eur J Pain , vol.12 , pp. 790-797
    • Palm, F.1    Mossner, R.2    Chen, Y.3
  • 14
    • 70349440715 scopus 로고    scopus 로고
    • Preclinical and early clinical investigations related to monoaminergic pain modulation
    • Bannister K, Bee LA, Dickenson AH. Preclinical and early clinical investigations related to monoaminergic pain modulation. Neurotherapeutics 2009; 6: 703-12.
    • (2009) Neurotherapeutics , vol.6 , pp. 703-712
    • Bannister, K.1    Bee, L.A.2    Dickenson, A.H.3
  • 15
    • 1542268262 scopus 로고    scopus 로고
    • Pain: Moving from symptom control toward mechanismspecific pharmacologic management
    • Woolf CJ. Pain: moving from symptom control toward mechanismspecific pharmacologic management. Ann Intern Med 2004; 140: 441-51.
    • (2004) Ann Intern Med , vol.140 , pp. 441-451
    • Woolf, C.J.1
  • 16
    • 0031404271 scopus 로고    scopus 로고
    • Peripheral and central hyperexcitability: Differential signs and symptoms in persistent pain
    • Coderre TJ, Katz J. Peripheral and central hyperexcitability: differential signs and symptoms in persistent pain. Behav Brain Sci 1997; 20: 404-19.
    • (1997) Behav Brain Sci , vol.20 , pp. 404-419
    • Coderre, T.J.1    Katz, J.2
  • 17
    • 70449130625 scopus 로고    scopus 로고
    • Should we switch from analgesics to the concept of Pain Modifying Analgesic Drugs (PMADs) in osteoarthritis and rheumatic chronic pain conditions?
    • Perrot S. Should we switch from analgesics to the concept of Pain Modifying Analgesic Drugs (PMADs) in osteoarthritis and rheumatic chronic pain conditions? Pain 2009; 146(3): 253-60.
    • (2009) Pain , vol.146 , Issue.3 , pp. 253-260
    • Perrot, S.1
  • 18
    • 33751326506 scopus 로고    scopus 로고
    • The concept of central sensitivity syndromes
    • Wallace DJ, Clauw DJ, Eds., Philadelphia, PA: Lippincott, Williams & Wilkins
    • Yunus MB. The concept of central sensitivity syndromes. In: Wallace DJ, Clauw DJ, Eds. Fibromyalgia & Other Central Pain Syndromes. Philadelphia, PA: Lippincott, Williams & Wilkins. 2005; 29-44.
    • (2005) Fibromyalgia & Other Central Pain Syndromes , pp. 29-44
    • Yunus, M.B.1
  • 20
    • 0029971214 scopus 로고    scopus 로고
    • The relationship between pain and depression
    • von Korff M, Simon G. The relationship between pain and depression. Br J Psychiatry Suppl 1996; 101-8.
    • (1996) Br J Psychiatry Suppl , pp. 101-108
    • von Korff, M.1    Simon, G.2
  • 21
    • 0030442838 scopus 로고    scopus 로고
    • Depression in the patient with chronic pain
    • Ruoff GE. Depression in the patient with chronic pain. J Fam Pract 1996; 43: S25-S33.
    • (1996) J Fam Pract , vol.43 , pp. 25-33
    • Ruoff, G.E.1
  • 22
    • 0030965057 scopus 로고    scopus 로고
    • Chronic painassociated depression: Antecedent or consequence of chronic pain
    • Fishbain DA, Cutler R, Rosomoff HL, Rosomoff RS. Chronic painassociated depression: antecedent or consequence of chronic pain? A review. Clin J Pain 1997; 13 (2): 116-37.
    • (1997) A Review. Clin J Pain , vol.13 , Issue.2 , pp. 116-137
    • Fishbain, D.A.1    Cutler, R.2    Rosomoff, H.L.3    Rosomoff, R.S.4
  • 23
    • 0141832226 scopus 로고    scopus 로고
    • Persistent pain and depression: A biopsychosocial perspective
    • Campbell LC, Clauw DJ, Keefe FJ. Persistent pain and depression: a biopsychosocial perspective. Biol Psychiatry 2003; 54: 399-409.
    • (2003) Biol Psychiatry , vol.54 , pp. 399-409
    • Campbell, L.C.1    Clauw, D.J.2    Keefe, F.J.3
  • 24
    • 4644255535 scopus 로고    scopus 로고
    • Common pathways of depression and pain
    • Delgado PL. Common pathways of depression and pain. J Clin Psychiatry 2004; 65 (Suppl. 12): 16-9.
    • (2004) J Clin Psychiatry , vol.65 , Issue.SUPPL. 12 , pp. 16-19
    • Delgado, P.L.1
  • 25
    • 6344282277 scopus 로고    scopus 로고
    • Understanding pain in depression
    • Stahl S, Briley M. Understanding pain in depression. Hum Psychopharmacol 2004; 19 (Suppl. 1): S9-S13.
    • (2004) Hum Psychopharmacol , vol.19 , Issue.SUPPL. 1 , pp. 9-13
    • Stahl, S.1    Briley, M.2
  • 26
    • 0031612907 scopus 로고    scopus 로고
    • Anna-Monika-Prize paper. The hypothalamic-pituitaryadrenal system in depression
    • Heuser I. Anna-Monika-Prize paper. The hypothalamic-pituitaryadrenal system in depression. Pharmacopsychiatry 1998; 31: 10-13.
    • (1998) Pharmacopsychiatry , vol.31 , pp. 10-13
    • Heuser, I.1
  • 27
    • 0035184459 scopus 로고    scopus 로고
    • Chronic pain, chronic stress and depression: Coincidence or consequence?
    • Blackburn-Munro G, Blackburn-Munro RE. Chronic pain, chronic stress and depression: coincidence or consequence? J Neuroendocrinol 2001; 13: 1009-23.
    • (2001) J Neuroendocrinol , vol.13 , pp. 1009-1023
    • Blackburn-Munro, G.1    Blackburn-Munro, R.E.2
  • 28
    • 2342592548 scopus 로고    scopus 로고
    • Hypothalamic-pituitary-adrenal axis dysfunction as a contributory factor to chronic pain and depression
    • Blackburn-Munro G. Hypothalamic-pituitary-adrenal axis dysfunction as a contributory factor to chronic pain and depression. Curr Pain Headache Rep 2004; 8: 116-24.
    • (2004) Curr Pain Headache Rep , vol.8 , pp. 116-124
    • Blackburn-Munro, G.1
  • 30
    • 0027353096 scopus 로고
    • The role of corticotropin-releasing factor in the pathophysiology of affective and anxiety disorders: Laboratory and clinical studies
    • Owens MJ, Nemeroff CB. The role of corticotropin-releasing factor in the pathophysiology of affective and anxiety disorders: laboratory and clinical studies. Ciba Found Symp 1993; 172: 296-308.
    • (1993) Ciba Found Symp , vol.172 , pp. 296-308
    • Owens, M.J.1    Nemeroff, C.B.2
  • 31
    • 0035280252 scopus 로고    scopus 로고
    • Glucocorticoid receptors in major depression: Relevance to pathophysiology and treatment
    • Pariante CM, Miller AH. Glucocorticoid receptors in major depression: relevance to pathophysiology and treatment. Biol Psychiatry 2001; 49(5): 391-404.
    • (2001) Biol Psychiatry , vol.49 , Issue.5 , pp. 391-404
    • Pariante, C.M.1    Miller, A.H.2
  • 32
    • 20644472635 scopus 로고    scopus 로고
    • Human brain mechanisms of pain perception and regulation in health and disease
    • Apkarian AV, Bushnell MC, Treede RD, Zubieta JK. Human brain mechanisms of pain perception and regulation in health and disease. Eur J Pain 2005; 9(4): 463-84.
    • (2005) Eur J Pain , vol.9 , Issue.4 , pp. 463-484
    • Apkarian, A.V.1    Bushnell, M.C.2    Treede, R.D.3    Zubieta, J.K.4
  • 33
    • 0034667345 scopus 로고    scopus 로고
    • Neuroimaging studies of mood disorders
    • Drevets WC. Neuroimaging studies of mood disorders. Biol Psychiatry 2000; 48: 813-29.
    • (2000) Biol Psychiatry , vol.48 , pp. 813-29
    • Drevets, W.C.1
  • 34
    • 0037322513 scopus 로고    scopus 로고
    • Differential sensitization of amygdale neurons to afferent inputs in a model of arthritic pain
    • Neugebauer V, Li W. Differential sensitization of amygdale neurons to afferent inputs in a model of arthritic pain. J Neurophysiol 2003; 89: 716-27.
    • (2003) J Neurophysiol , vol.89 , pp. 716-727
    • Neugebauer, V.1    Li, W.2
  • 35
    • 33745607370 scopus 로고    scopus 로고
    • New and emerging treatment options for neuropathic pain
    • Gidal BE. New and emerging treatment options for neuropathic pain. Am J Manag Care 2006; 12(Suppl 9): S269-S278.
    • (2006) Am J Manag Care , vol.12 , Issue.SUPPL. 9 , pp. 269-278
    • Gidal, B.E.1
  • 36
    • 33746792050 scopus 로고    scopus 로고
    • Neuropathic pain: A practical guide for the clinician
    • Gilron I, Watson CP, Cahill CM, Moulin DE. Neuropathic pain: a practical guide for the clinician. CMAJ 2006; 175(3): 265-75.
    • (2006) CMAJ , vol.175 , Issue.3 , pp. 265-275
    • Gilron, I.1    Watson, C.P.2    Cahill, C.M.3    Moulin, D.E.4
  • 38
    • 0035677108 scopus 로고    scopus 로고
    • Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors
    • Bymaster FP, Dreshfield-Ahmad LJ, Threlkeld PG, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology 2001; 25(6): 871-80.
    • (2001) Neuropsychopharmacology , vol.25 , Issue.6 , pp. 871-880
    • Bymaster, F.P.1    Dreshfield-Ahmad, L.J.2    Threlkeld, P.G.3
  • 39
    • 0036236178 scopus 로고    scopus 로고
    • Dual serotonin and noradrenaline uptake inhibitor class of antidepressants potential for greater efficacy or just hype?
    • Wong DT, Bymaster FP. Dual serotonin and noradrenaline uptake inhibitor class of antidepressants potential for greater efficacy or just hype? Prog Drug Res 2002; 58: 169-222.
    • (2002) Prog Drug Res , vol.58 , pp. 169-222
    • Wong, D.T.1    Bymaster, F.P.2
  • 40
    • 0024438481 scopus 로고
    • Modified formalin test: Characteristic biphasic pain response
    • Shibata M, Ohkubo T, Takahashi H, Inoki R. Modified formalin test: characteristic biphasic pain response. Pain 1989; 38: 347-52.
    • (1989) Pain , vol.38 , pp. 347-352
    • Shibata, M.1    Ohkubo, T.2    Takahashi, H.3    Inoki, R.4
  • 41
    • 0025014877 scopus 로고
    • The rat paw formalin test: Comparison of noxious agents
    • Wheeler-Aceto H, Porreca F, Cowan A. The rat paw formalin test: comparison of noxious agents. Pain 1990; 40: 229-38.
    • (1990) Pain , vol.40 , pp. 229-238
    • Wheeler-Aceto, H.1    Porreca, F.2    Cowan, A.3
  • 43
    • 0026727999 scopus 로고
    • An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat
    • Kim SH, Chung JM. An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. Pain 1992; 50: 355-63.
    • (1992) Pain , vol.50 , pp. 355-363
    • Kim, S.H.1    Chung, J.M.2
  • 44
    • 0023924046 scopus 로고
    • A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia
    • Hargreaves K, Dubner R, Brown F, Flores C, Joris J. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 1988; 32: 77-88.
    • (1988) Pain , vol.32 , pp. 77-88
    • Hargreaves, K.1    Dubner, R.2    Brown, F.3    Flores, C.4    Joris, J.5
  • 45
    • 0002261078 scopus 로고
    • A method for determining loss of pain sensation
    • D'Amour FE, Smith DL. A method for determining loss of pain sensation. J Pharmacol Exp Ther 1941; 72: 74-9.
    • (1941) J Pharmacol Exp Ther , vol.72 , pp. 74-79
    • D'amour, F.E.1    Smith, D.L.2
  • 46
    • 6244309292 scopus 로고    scopus 로고
    • Efficacy of duloxetine, a potent and balanced serotoninnorepinephrine reuptake inhibitor in persistent pain models in rats
    • Iyengar S, Webster AA, Hemrick-Luecke SK, Xu JY, Simmons RM. Efficacy of duloxetine, a potent and balanced serotoninnorepinephrine reuptake inhibitor in persistent pain models in rats. J Pharmacol Exp Ther 2004; 311: 576-84.
    • (2004) J Pharmacol Exp Ther , vol.311 , pp. 576-584
    • Iyengar, S.1    Webster, A.A.2    Hemrick-Luecke, S.K.3    Xu, J.Y.4    Simmons, R.M.5
  • 47
    • 13244284671 scopus 로고    scopus 로고
    • Efficacy of duloxetine, a potent and balanced serotonergic and noradrenergic reuptake inhibitor, in inflammatory and acute pain models in rodents
    • Jones CK, Peters SC, Shannon HE. Efficacy of duloxetine, a potent and balanced serotonergic and noradrenergic reuptake inhibitor, in inflammatory and acute pain models in rodents. J Pharmacol Exp Ther 2005; 312: 726-32.
    • (2005) J Pharmacol Exp Ther , vol.312 , pp. 726-732
    • Jones, C.K.1    Peters, S.C.2    Shannon, H.E.3
  • 48
    • 0028395482 scopus 로고
    • Pain assessment: Global use of the Brief Pain Inventory
    • Cleeland CS, Ryan KM. Pain assessment: global use of the Brief Pain Inventory. Ann Acad Med Singapore 1994; 23: 129-38.
    • (1994) Ann Acad Med Singapore , vol.23 , pp. 129-138
    • Cleeland, C.S.1    Ryan, K.M.2
  • 49
    • 0031965568 scopus 로고    scopus 로고
    • The visual analog scale in the immediate postoperative period: Intrasubject variability and correlation with a numeric scale
    • DeLoach LJ, Higgins MS, Caplan AB, Stiff JL. The visual analog scale in the immediate postoperative period: intrasubject variability and correlation with a numeric scale. Anesth Analg 1998; 86: 102-6.
    • (1998) Anesth Analg , vol.86 , pp. 102-106
    • Deloach, L.J.1    Higgins, M.S.2    Caplan, A.B.3    Stiff, J.L.4
  • 50
  • 51
    • 0032842283 scopus 로고    scopus 로고
    • Diabetic neuropathy: Pathogenesis and therapy
    • Vinik AI. Diabetic neuropathy: pathogenesis and therapy. Am J Med 1999; 107(2B): 17S-26S.
    • (1999) Am J Med , vol.107 , Issue.2 B
    • Vinik, A.I.1
  • 52
    • 0036844605 scopus 로고    scopus 로고
    • Epidemiology and impact on quality of life of postherpetic neuralgia and painful diabetic neuropathy
    • Schmader KE. Epidemiology and impact on quality of life of postherpetic neuralgia and painful diabetic neuropathy. Clin J Pain 2002; 18(6): 350-54.
    • (2002) Clin J Pain , vol.18 , Issue.6 , pp. 350-354
    • Schmader, K.E.1
  • 53
    • 20444464304 scopus 로고    scopus 로고
    • Duloxetine vs. placebo in patients with painful diabetic neuropathy
    • Goldstein DJ, Lu Y, Detke MJ, Lee TC, Iyengar S. Duloxetine vs. placebo in patients with painful diabetic neuropathy. Pain 2005; 116: 109-18.
    • (2005) Pain , vol.116 , pp. 109-118
    • Goldstein, D.J.1    Lu, Y.2    Detke, M.J.3    Lee, T.C.4    Iyengar, S.5
  • 54
    • 33750341692 scopus 로고    scopus 로고
    • A randomized controlled trial of duloxetine in diabetic peripheral neuropathic pain
    • Wernicke JF, Pritchett YL, D'Souza DN, et al. A randomized controlled trial of duloxetine in diabetic peripheral neuropathic pain. Neurology 2006; 67(8): 1411-20.
    • (2006) Neurology , vol.67 , Issue.8 , pp. 1411-1420
    • Wernicke, J.F.1    Pritchett, Y.L.2    D'souza, D.N.3
  • 55
    • 28444459170 scopus 로고    scopus 로고
    • A double-blind, randomized multicenter trial comparing duloxetine with placebo in the management of diabetic peripheral neuropathic pain
    • Raskin J, Pritchett YL, Wang F, et al. A double-blind, randomized multicenter trial comparing duloxetine with placebo in the management of diabetic peripheral neuropathic pain. Pain Med 2005; 6(5): 346-56.
    • (2005) Pain Med , vol.6 , Issue.5 , pp. 346-356
    • Raskin, J.1    Pritchett, Y.L.2    Wang, F.3
  • 56
    • 0028077808 scopus 로고
    • A practical two-step quantitative clinical and electrophysiological assessment for the diagnosis and staging of diabetic neuropathy
    • Feldman EL, Stevens MJ, Thomas PK, Brown MB, Canal N, Greene DA. A practical two-step quantitative clinical and electrophysiological assessment for the diagnosis and staging of diabetic neuropathy. Diabetes Care 1994; 17(11): 1281-9.
    • (1994) Diabetes Care , vol.17 , Issue.11 , pp. 1281-1289
    • Feldman, E.L.1    Stevens, M.J.2    Thomas, P.K.3    Brown, M.B.4    Canal, N.5    Greene, D.A.6
  • 57
    • 0025266660 scopus 로고
    • The American College of Rheumatology 1990 criteria for the classification of fibromyalgia. Report of the Multicenter Criteria Committee
    • Wolfe F, Smythe HA, Yunus MB, et al. The American College of Rheumatology 1990 criteria for the classification of fibromyalgia. Report of the Multicenter Criteria Committee. Arthritis Rheum 1990; 33(2): 160-72.
    • (1990) Arthritis Rheum , vol.33 , Issue.2 , pp. 160-172
    • Wolfe, F.1    Smythe, H.A.2    Yunus, M.B.3
  • 58
    • 0029981949 scopus 로고    scopus 로고
    • The relationship between fibromyalgia and major depressive disorder
    • Hudson JI, Pope HG Jr. The relationship between fibromyalgia and major depressive disorder. Rheum Dis Clin North Am 1996; 22(2): 285-303.
    • (1996) Rheum Dis Clin North Am , vol.22 , Issue.2 , pp. 285-303
    • Hudson, J.I.1    Pope, H.G.2
  • 59
    • 4444381930 scopus 로고    scopus 로고
    • A double-blind, multicenter trial comparing duloxetine with placebo in the treatment of fibromyalgia patients with or without major depressive disorder
    • Arnold LM, Lu Y, Crofford LJ, et al. A double-blind, multicenter trial comparing duloxetine with placebo in the treatment of fibromyalgia patients with or without major depressive disorder. Arthritis Rheum 2004; 50(9): 2974-84.
    • (2004) Arthritis Rheum , vol.50 , Issue.9 , pp. 2974-2984
    • Arnold, L.M.1    Lu, Y.2    Crofford, L.J.3
  • 60
    • 28644442626 scopus 로고    scopus 로고
    • A randomized, doubleblind, placebo-controlled trial of duloxetine in the treatment of women with fibromyalgia with or without major depressive disorder
    • Arnold LM, Rosen A, Pritchett YL, et al. A randomized, doubleblind, placebo-controlled trial of duloxetine in the treatment of women with fibromyalgia with or without major depressive disorder. Pain 2005; 119(1-3): 5-15.
    • (2005) Pain , vol.119 , Issue.1-3 , pp. 5-15
    • Arnold, L.M.1    Rosen, A.2    Pritchett, Y.L.3
  • 61
    • 43549091316 scopus 로고    scopus 로고
    • Efficacy and safety of duloxetine for treatment of fibromyalgia in patients with or without major depressive disorder: Results from a 6-month randomized, double-blind, placebo-controlled, fixed-dosed trial
    • Russell IJ, Mease P, Smith TR, et al. Efficacy and safety of duloxetine for treatment of fibromyalgia in patients with or without major depressive disorder: results from a 6-month randomized, double-blind, placebo-controlled, fixed-dosed trial. Pain 2008; 136: 432-44.
    • (2008) Pain , vol.136 , pp. 432-444
    • Russell, I.J.1    Mease, P.2    Smith, T.R.3
  • 62
    • 67649373629 scopus 로고    scopus 로고
    • A 6-month double-blind, placebo-controlled, randomized clinical trial of duloxetine for the treatment of fibromyalgia
    • Chappell AS, Bradley LA, Wiltse C, Detke MJ, D'Souza DN, Spaeth M. A 6-month double-blind, placebo-controlled, randomized clinical trial of duloxetine for the treatment of fibromyalgia. Int J Gen Med 2008; 1: 91-102.
    • (2008) Int J Gen Med , vol.1 , pp. 91-102
    • Chappell, A.S.1    Bradley, L.A.2    Wiltse, C.3    Detke, M.J.4    D'souza, D.N.5    Spaeth, M.6
  • 63
    • 0026165648 scopus 로고
    • The Fibromyalgia Impact Questionnaire: Development and validation
    • Burckhardt CS, Clark SR, Bennett RM. The Fibromyalgia Impact Questionnaire: Development and validation. J heumatol 1991; 18: 728-33.
    • (1991) J Heumatol , vol.18 , pp. 728-733
    • Burckhardt, C.S.1    Clark, S.R.2    Bennett, R.M.3
  • 64
    • 84862908787 scopus 로고    scopus 로고
    • Efficacy of duloxetine in patients with fibromyalgia: Pooled analysis of four placebo-controlled clinical trials
    • Arnold LM, Clauw DJ, Wohlreich MM, et al. Efficacy of duloxetine in patients with fibromyalgia: Pooled analysis of four placebo-controlled clinical trials. Prim Care Companion J Clin Psychiatry 2009; 11(5): 237-44.
    • (2009) Prim Care Companion J Clin Psychiatry , vol.11 , Issue.5 , pp. 237-244
    • Arnold, L.M.1    Clauw, D.J.2    Wohlreich, M.M.3
  • 65
    • 0021040528 scopus 로고
    • Pain as a symptom in depressive disorders. II. Relationship to personality traits as assessed by means of KSP
    • von Knorring L, Perris C, Eisemann M, Eriksson U, Perris H. Pain as a symptom in depressive disorders. II. Relationship to personality traits as assessed by means of KSP. Pain 1983; 17(4): 377-84.
    • (1983) Pain , vol.17 , Issue.4 , pp. 377-384
    • von Knorring, L.1    Perris, C.2    Eisemann, M.3    Eriksson, U.4    Perris, H.5
  • 66
  • 69
    • 33748688471 scopus 로고    scopus 로고
    • Duloxetine in the treatment of major depressive disorder: A placebo- and paroxetine-controlled trial
    • Perahia DG, Wang F, Mallinckrodt CH, Walker DJ, Detke MJ. Duloxetine in the treatment of major depressive disorder: a placebo- and paroxetine-controlled trial. Eur Psychiatry 2006; 21: 367-78.
    • (2006) Eur Psychiatry , vol.21 , pp. 367-378
    • Perahia, D.G.1    Wang, F.2    Mallinckrodt, C.H.3    Walker, D.J.4    Detke, M.J.5
  • 70
    • 0036232639 scopus 로고    scopus 로고
    • Duloxetine, 60 mg once daily, for major depressive disorder: A randomized double-blind placebo-controlled trial
    • Detke MJ, Lu Y, Goldstein DJ, Hayes JR, Demitrack MA. Duloxetine, 60 mg once daily, for major depressive disorder: a randomized double-blind placebo-controlled trial. J Clin Psychiatry 2002; 63: 308-15.
    • (2002) J Clin Psychiatry , vol.63 , pp. 308-315
    • Detke, M.J.1    Lu, Y.2    Goldstein, D.J.3    Hayes, J.R.4    Demitrack, M.A.5
  • 71
    • 0036829053 scopus 로고    scopus 로고
    • Duloxetine 60 mg once daily dosing versus placebo in the acute treatment of major depression
    • Detke MJ, Lu Y, Goldstein DJ, McNamara RK, Demitrack MA. Duloxetine 60 mg once daily dosing versus placebo in the acute treatment of major depression. J Psychiatr Res 2002; 36: 383-90.
    • (2002) J Psychiatr Res , vol.36 , pp. 383-390
    • Detke, M.J.1    Lu, Y.2    Goldstein, D.J.3    McNamara, R.K.4    Demitrack, M.A.5
  • 73
    • 37049001394 scopus 로고    scopus 로고
    • Efficacy and safety of duloxetine 60 mg once daily in the treatment of pain in patients with major depressive disorder and at least moderate pain of unknown etiology: A randomized controlled trial
    • Brecht S, Courtecuisse C, Debieuvre C, et al. Efficacy and safety of duloxetine 60 mg once daily in the treatment of pain in patients with major depressive disorder and at least moderate pain of unknown etiology: a randomized controlled trial. J Clin Psychiatry 2007; 68: 1707-16.
    • (2007) J Clin Psychiatry , vol.68 , pp. 1707-1716
    • Brecht, S.1    Courtecuisse, C.2    Debieuvre, C.3
  • 74
    • 34250832737 scopus 로고    scopus 로고
    • Efficacy of duloxetine on cognition, depression, and pain in elderly patients with major depressive disorder: An 8-week, double-blind, placebo-controlled trial
    • Raskin J, Wiltse CG, Siegal A, et al. Efficacy of duloxetine on cognition, depression, and pain in elderly patients with major depressive disorder: an 8-week, double-blind, placebo-controlled trial. Am J Psychiatry 2007; 164 (6): 900-9.
    • (2007) Am J Psychiatry , vol.164 , Issue.6 , pp. 900-909
    • Raskin, J.1    Wiltse, C.G.2    Siegal, A.3
  • 75
    • 0030861766 scopus 로고    scopus 로고
    • The visual analogue pain intensity scale: What is moderate pain in millimetres?
    • Collins SL, Moore RA, McQuay HJ. The visual analogue pain intensity scale: what is moderate pain in millimetres? Pain 1997; 72(1-2): 95-7.
    • (1997) Pain , vol.72 , Issue.1-2 , pp. 95-97
    • Collins, S.L.1    Moore, R.A.2    McQuay, H.J.3
  • 76
    • 33646336858 scopus 로고    scopus 로고
    • Duloxetine for the treatment of major depressive disorder: A closer look at efficacy and safety data across the approved dose range
    • Mallinckrodt CH, Prakash A, Andorn AC, Watkin JG, Wohlreich MM. Duloxetine for the treatment of major depressive disorder: A closer look at efficacy and safety data across the approved dose range. J Psychiatr Res 2006; 40(4): 337-48.
    • (2006) J Psychiatr Res , vol.40 , Issue.4 , pp. 337-348
    • Mallinckrodt, C.H.1    Prakash, A.2    Andorn, A.C.3    Watkin, J.G.4    Wohlreich, M.M.5
  • 77
    • 0034074161 scopus 로고    scopus 로고
    • Prevalence of depression and its treatment in an elderly population: The Cache County study
    • Steffens DC, Skoog I, Norton MC, et al. Prevalence of depression and its treatment in an elderly population: the Cache County study. Arch Gen Psychiatry 2000; 57(6): 601-7.
    • (2000) Arch Gen Psychiatry , vol.57 , Issue.6 , pp. 601-607
    • Steffens, D.C.1    Skoog, I.2    Norton, M.C.3
  • 78
    • 0031722132 scopus 로고    scopus 로고
    • Psychic and somatic anxiety: Worries, somatic symptoms and physiological changes
    • Hoehn-Saric R. Psychic and somatic anxiety: worries, somatic symptoms and physiological changes. Acta Psychiatr Scand Suppl 1998; 393: 32-8.
    • (1998) Acta Psychiatr Scand Suppl , vol.393 , pp. 32-38
    • Hoehn-Saric, R.1
  • 79
    • 0034970234 scopus 로고    scopus 로고
    • What is generalized anxiety disorder
    • Rickels K, Rynn MA. What is generalized anxiety disorder? J Clin Psychiatry 2001; 62 Suppl 11: 4-12.
    • (2001) J Clin Psychiatry , vol.62 , Issue.SUPPL. 11 , pp. 4-12
    • Rickels, K.1    Rynn, M.A.2
  • 80
    • 0036093608 scopus 로고    scopus 로고
    • Generalized anxiety and depression in primary care: Prevalence, recognition, and management
    • Wittchen HU, Kessler RC, Bessdo K, Krause P, Höfler M, Hoyer J. Generalized anxiety and depression in primary care: prevalence, recognition, and management. J Clin Psychiatry 2002; 63 Suppl 8: 24-34.
    • (2002) J Clin Psychiatry , vol.63 , Issue.SUPPL. 8 , pp. 24-34
    • Wittchen, H.U.1    Kessler, R.C.2    Bessdo, K.3    Krause, P.4    Höfler, M.5    Hoyer, J.6
  • 81
    • 0027438702 scopus 로고
    • Symptoms in the community. Prevalence, classification, and psychiatric comorbidity
    • Kroenke K, Price RK. Symptoms in the community. Prevalence, classification, and psychiatric comorbidity. Arch Intern Med 1993; 153(21): 2474-80.
    • (1993) Arch Intern Med , vol.153 , Issue.21 , pp. 2474-2480
    • Kroenke, K.1    Price, R.K.2
  • 82
    • 4344702848 scopus 로고    scopus 로고
    • Depression and anxiety associated with three pain conditions: Results from a nationally representative sample
    • McWilliams LA, Goodwin RD, Cox BJ. Depression and anxiety associated with three pain conditions: results from a nationally representative sample. Pain 2004; 111(1-2): 77-83.
    • (2004) Pain , vol.111 , Issue.1-2 , pp. 77-83
    • McWilliams, L.A.1    Goodwin, R.D.2    Cox, B.J.3
  • 83
    • 0021800572 scopus 로고
    • Chronic pain and depression. II. Symptoms of anxiety in chronic low back pain patients and their relationship to subtypes of depression
    • Krishnan KR, France RD, Pelton S, McCann UD, Davidson J, Urban BJ. Chronic pain and depression. II. Symptoms of anxiety in chronic low back pain patients and their relationship to subtypes of depression. Pain 1985; 22(3): 289-94.
    • (1985) Pain , vol.22 , Issue.3 , pp. 289-294
    • Krishnan, K.R.1    France, R.D.2    Pelton, S.3    McCann, U.D.4    Davidson, J.5    Urban, B.J.6
  • 84
    • 0027087127 scopus 로고
    • Chest pain in generalized anxiety disorder
    • Carter CS, Maddock RJ. Chest pain in generalized anxiety disorder. Int J Psychiatry Med 1992; 22(3): 291-98.
    • (1992) Int J Psychiatry Med , vol.22 , Issue.3 , pp. 291-298
    • Carter, C.S.1    Maddock, R.J.2
  • 85
    • 0027240906 scopus 로고
    • Somatization and the recognition of depression and anxiety in primary care
    • Kirmayer LJ, Robbins JM, Dworkind M, Yaffe MJ. Somatization and the recognition of depression and anxiety in primary care. Am J Psychiatry 1993; 150(5): 734-41.
    • (1993) Am J Psychiatry , vol.150 , Issue.5 , pp. 734-741
    • Kirmayer, L.J.1    Robbins, J.M.2    Dworkind, M.3    Yaffe, M.J.4
  • 86
    • 15744381914 scopus 로고    scopus 로고
    • Generalized anxiety disorder in medical practice
    • Hoehn-Saric R. Generalized anxiety disorder in medical practice. Prim Psychiatry 2005; 12: 30-4.
    • (2005) Prim Psychiatry , vol.12 , pp. 30-34
    • Hoehn-Saric, R.1
  • 87
    • 0032534952 scopus 로고    scopus 로고
    • Generalized anxiety disorder: Neurobiological and pharmacotherapeutic perspectives
    • Connor KM, Davidson JR. Generalized anxiety disorder: neurobiological and pharmacotherapeutic perspectives. Biol Psychiatry 1998; 44(12): 1286-94.
    • (1998) Biol Psychiatry , vol.44 , Issue.12 , pp. 1286-1294
    • Connor, K.M.1    Davidson, J.R.2
  • 88
    • 34147180827 scopus 로고    scopus 로고
    • Efficacy of duloxetine for the treatment of generalized anxiety disorder: Implications for primary care physicians
    • Koponen H, Allgulander C, Erickson J, et al. Efficacy of duloxetine for the treatment of generalized anxiety disorder: Implications for primary care physicians. Prim Care Companion J Clin Psychiatry 2007; 9(2): 100-7.
    • (2007) Prim Care Companion J Clin Psychiatry , vol.9 , Issue.2 , pp. 100-107
    • Koponen, H.1    Allgulander, C.2    Erickson, J.3
  • 89
    • 41849137610 scopus 로고    scopus 로고
    • Efficacy and safety of duloxetine in the treatment of generalized anxiety disorder: A flexible-dose, progressive-titration, placebo-controlled trial
    • Rynn M, Russell J, Erickson J, et al. Efficacy and safety of duloxetine in the treatment of generalized anxiety disorder: a flexible-dose, progressive-titration, placebo-controlled trial. Depress Anxiety 2008; 25(3): 182-9.
    • (2008) Depress Anxiety , vol.25 , Issue.3 , pp. 182-189
    • Rynn, M.1    Russell, J.2    Erickson, J.3
  • 90
    • 0034748159 scopus 로고    scopus 로고
    • Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale
    • Farrar JT, Young JP Jr, LaMoreaux L, Werth JL, Poole RM. Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale. Pain 2001; 94(2): 149-58.
    • (2001) Pain , vol.94 , Issue.2 , pp. 149-158
    • Farrar, J.T.1    Young Jr., J.P.2    Lamoreaux, L.3    Werth, J.L.4    Poole, R.M.5
  • 91
    • 34547934677 scopus 로고    scopus 로고
    • Assessment of pain in rheumatoid arthritis: Minimal clinically significant difference, predictors, and the effect of anti-tumor necrosis factor therapy
    • Wolfe F, Michaud K. Assessment of pain in rheumatoid arthritis: Minimal clinically significant difference, predictors, and the effect of anti-tumor necrosis factor therapy. J Rheumatology 2007; 34(8): 1674-83.
    • (2007) J Rheumatology , vol.34 , Issue.8 , pp. 1674-1683
    • Wolfe, F.1    Michaud, K.2
  • 92
    • 37349086775 scopus 로고    scopus 로고
    • Duloxetine for the management of diabetes peripheral neuropathic pain: Evidencedbased findings from post hoc analysis of three multicenter, randomized, double-blind, placebo-controlled, parallel-group studies
    • Kajdazs DK, Iyengar S, Desaiah D, et al. Duloxetine for the management of diabetes peripheral neuropathic pain: Evidencedbased findings from post hoc analysis of three multicenter, randomized, double-blind, placebo-controlled, parallel-group studies. Clin Thera 2007; 29 Suppl: 2536-2546.
    • (2007) Clin Thera , vol.29 , Issue.SUPPL , pp. 2536-2546
    • Kajdazs, D.K.1    Iyengar, S.2    Desaiah, D.3
  • 93
    • 33746740474 scopus 로고    scopus 로고
    • Treatment benefits of duloxetine in major depressive disorder as assessed by the number needed to treat
    • Cookson J, Gilaberte I, Desaiah D, Kajdazs DK. Treatment benefits of duloxetine in major depressive disorder as assessed by the number needed to treat. Int Clin Psychopharmacol 2006; 21: 267-73.
    • (2006) Int Clin Psychopharmacol , vol.21 , pp. 267-273
    • Cookson, J.1    Gilaberte, I.2    Desaiah, D.3    Kajdazs, D.K.4
  • 94
    • 77951097481 scopus 로고    scopus 로고
    • Profile of adverse events with duloxetine treatment: A pooled analysis of placebo-controlled studies
    • Brunton S, Wang F, Edwards SE, et al. Profile of adverse events with duloxetine treatment: a pooled analysis of placebo-controlled studies. Drug Saf 2010; 33(5): 393-407.
    • (2010) Drug Saf , vol.33 , Issue.5 , pp. 393-407
    • Brunton, S.1    Wang, F.2    Edwards, S.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.