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Volumn 666, Issue 1-3, 2011, Pages 150-157

Molecular mechanism of vasorelaxant and antiatherogenic effects of the statins in the human saphenous vein graft

Author keywords

Coronary artery bypass surgery; Human saphenous vein graft; Molecular mechanism; Statin

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ANGIOTENSIN II; CAPTOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE; ENALAPRIL; FLUINDOSTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INDOMETACIN; MEVALONOLACTONE; N(G) NITROARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHOSPHOLIPASE A2; PRAVASTATIN; PROSTAGLANDIN SYNTHASE; RHO KINASE;

EID: 79960026090     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.05.013     Document Type: Article
Times cited : (6)

References (38)
  • 1
    • 11444251238 scopus 로고    scopus 로고
    • Prostaglandins mediate the cardioprotective effects of atorvastatin against ischemia-reperfusion injury
    • DOI 10.1016/j.cardiores.2004.10.018, PII S0008636304004651
    • Y. Birnbaum, Y. Ye, S. Rosanio, S. Tavackoli, Z.Y. Hu, E.R. Schwarz, and B.F. Uretsky Prostaglandins mediate the cardioprotective effects of atorvastatin against ischemia-reperfusion injury Cardiovasc. Res. 65 2005 345 355 (Pubitemid 40082476)
    • (2005) Cardiovascular Research , vol.65 , Issue.2 , pp. 345-355
    • Birnbaum, Y.1    Ye, Y.2    Rosanio, S.3    Tavackoli, S.4    Hu, Z.-Y.5    Schwarz, E.R.6    Uretsky, B.F.7
  • 2
    • 33750965225 scopus 로고    scopus 로고
    • Simvastatin Reduces CD40 Expression in an Experimental Model of Early Arterialization of Saphenous Vein Graft
    • DOI 10.1016/j.jss.2006.06.013, PII S0022480406003222
    • M. Chello, C. Spadaccio, A. Anselmi, G. Patti, M. Lusini, G. Di Sciascio, and E. Covino Simvastatin reduces CD40 expression in an experimental model of early arterialization of saphenous vein graft J. Surg. Res. 136 2006 302 308 (Pubitemid 44737844)
    • (2006) Journal of Surgical Research , vol.136 , Issue.2 , pp. 302-308
    • Chello, M.1    Spadaccio, C.2    Anselmi, A.3    Patti, G.4    Lusini, M.5    Di Sciascio, G.6    Covino, E.7
  • 3
    • 8644249173 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors induce COX-2 gene expression in murine macrophages: Role of MAPK cascades and promoter elements for CREB and C/EBPβ
    • DOI 10.1016/j.yexcr.2004.05.039, PII S0014482704004422
    • J.C. Chen, K.C. Huang, B. Wingerd, W.T. Wu, and W.W. Lin HMG-CoA reductase inhibitors induce COX-2 gene expression in murine macrophages: role of MAPK cascades and promoter elements for CREB and C/EBPbeta Exp. Cell. Res. 301 2004 305 319 (Pubitemid 39504982)
    • (2004) Experimental Cell Research , vol.301 , Issue.2 , pp. 305-319
    • Chen, J.-C.1    Huang, K.-C.2    Wingerd, B.3    Wu, W.-T.4    Lin, W.-W.5
  • 4
    • 0037428209 scopus 로고    scopus 로고
    • Long-term vitamin C treatment increases vascular tetrahydrobiopterin levels and nitric oxide synthase activity
    • DOI 10.1161/01.RES.0000049166.33035.62
    • L.V. d'Uscio, S. Milstien, D. Richardson, L. Smith, and Z.S. Katusic Long-term vitamin C treatment increases vascular tetrahydrobiopterin levels and nitric oxide synthase activity Circ. Res. 92 2003 88 95 (Pubitemid 36105611)
    • (2003) Circulation Research , vol.92 , Issue.1 , pp. 88-95
    • D'Uscio, L.V.1    Milstien, S.2    Richardson, D.3    Smith, L.4    Katusic, Z.S.5
  • 5
    • 23944489864 scopus 로고    scopus 로고
    • Effect of vein graft harvesting on endothelial nitric oxide synthase and nitric oxide production
    • DOI 10.1016/j.athoracsur.2005.03.042, PII S0003497505004005
    • M.R. Dashwood, K. Savage, A. Dooley, X. Shi-Wen, D.J. Abraham, and D.S. Souza Effect of vein graft harvesting on endothelial nitric oxide synthase and nitric oxide production Ann. Thorac. Surg. 80 2005 939 944 (Pubitemid 41196788)
    • (2005) Annals of Thoracic Surgery , vol.80 , Issue.3 , pp. 939-944
    • Dashwood, M.R.1    Savage, K.2    Dooley, A.3    Shi-Wen, X.4    Abraham, D.J.5    Souza, D.S.R.6
  • 8
    • 7644242146 scopus 로고    scopus 로고
    • Effects of statins on endothelium and signaling mechanisms
    • DOI 10.1161/01.STR.0000143319.73503.38
    • M. Endres, and U. Laufs Effects of statins on endothelium and signaling mechanisms Stroke 35 2004 2708 2711 (Pubitemid 39458376)
    • (2004) Stroke , vol.35 , Issue.11 SUPPL. 1 , pp. 2708-2711
    • Endres, M.1    Laufs, U.2
  • 9
    • 35548983434 scopus 로고    scopus 로고
    • Patency of internal thoracic artery compared to vein grafts - Postoperative angiographic findings in 1189 symptomatic patients in 12 years
    • DOI 10.1055/s-2007-965372
    • B. Gansera, F. Schmidtler, I. Angelis, T. Kiask, B.M. Kemkes, and F. Botzenhardt Patency of internal thoracic artery compared to vein grafts-postoperative angiographic findings in 1189 symptomatic patients in 12 years Thorac. Cardiovasc. Surg. 55 2007 412 417 (Pubitemid 350013792)
    • (2007) Thoracic and Cardiovascular Surgeon , vol.55 , Issue.7 , pp. 412-417
    • Gansera, B.1    Schmidtler, F.2    Angelis, I.3    Kiask, T.4    Kemkes, B.M.5    Botzenhardt, F.6
  • 10
    • 0030818151 scopus 로고    scopus 로고
    • Effects of nitric oxide and superoxide on relaxation in human artery and vein
    • DOI 10.1016/S0021-9150(97)00114-7
    • C.A. Hamilton, G. Berg, M. Mcintyre, A.R. Mcphaden, J.L. Reid, and A.F. Dominiczak Effects of nitric oxide and superoxide on relaxation in human artery and vein Atherosclerosis 133 1997 77 86 (Pubitemid 27322120)
    • (1997) Atherosclerosis , vol.133 , Issue.1 , pp. 77-86
    • Hamilton, C.A.1    Berg, G.2    Mcintyre, M.3    Mcphaden, A.R.4    Reid, J.L.5    Dominiczak, A.F.6
  • 11
    • 33748741380 scopus 로고    scopus 로고
    • Vein Graft Harvesting Induces Inflammation and Impairs Vessel Reactivity
    • DOI 10.1016/j.athoracsur.2006.05.038, PII S0003497506010241
    • K. Hinokiyama, G. Valen, S. Tokuno, J.B. Vedin, and J. Vaage Vein graft harvesting induces inflammation and impairs vessel reactivity Ann. Thorac. Surg. 82 2006 1458 1464 (Pubitemid 44402355)
    • (2006) Annals of Thoracic Surgery , vol.82 , Issue.4 , pp. 1458-1464
    • Hinokiyama, K.1    Valen, G.2    Tokuno, S.3    Vedin, J.B.4    Vaage, J.5
  • 13
    • 0032896636 scopus 로고    scopus 로고
    • Pravastatin sodium activates endothelial nitric oxide synthase independent of its cholesterol-lowering actions
    • DOI 10.1016/S0735-1097(98)00514-2, PII S0735109798005142
    • W.H. Kaesemeyer, R.B. Caldwell, J. Huang, and R.W. Caldwell Pravastatin sodium activates endothelial nitric oxide synthase independent of its cholesterol-lowering actions J. Am. Coll. Cardiol. 33 1999 234 241 (Pubitemid 29064099)
    • (1999) Journal of the American College of Cardiology , vol.33 , Issue.1 , pp. 234-241
    • Kaesemeyer, W.H.1    Caldwell, R.B.2    Huang, J.3    William Caldwell, R.4
  • 14
    • 26844490920 scopus 로고    scopus 로고
    • Effects of resveratrol in storage solution on adhesion molecule expression and nitric oxide synthesis in vein grafts
    • DOI 10.1016/j.athoracsur.2005.04.039, PII S0003497505007393
    • S. Kaplan, J.A. Morgan, G. Bisleri, F.H. Cheema, H.O. Akman, V.K. Topkara, and M.C. Oz Effects of resveratrol in storage solution on adhesion molecule expression and nitric oxide synthesis in vein grafts Ann. Thorac. Surg. 80 2005 1773 1778 (Pubitemid 41464299)
    • (2005) Annals of Thoracic Surgery , vol.80 , Issue.5 , pp. 1773-1778
    • Kaplan, S.1    Morgan, J.A.2    Bisleri, G.3    Cheema, F.H.4    Akman, H.O.5    Topkara, V.K.6    Oz, M.C.7
  • 15
    • 27644497981 scopus 로고    scopus 로고
    • Statins prevent pulsatile stretch-induced proliferation of human saphenous vein smooth muscle cells via inhibition of Rho/Rho-kinase pathway
    • DOI 10.1016/j.cardiores.2005.07.002, PII S0008636305003676
    • T. Kozai, M. Eto, Z. Yang, H. Shimokawa, and T.F. Lüscher Statins prevent pulsatile stretch-induced proliferation of human saphenous vein smooth muscle cells via inhibition of Rho/Rho-kinase pathway Cardiovasc. Res. 68 2005 475 482 (Pubitemid 41566567)
    • (2005) Cardiovascular Research , vol.68 , Issue.3 , pp. 475-482
    • Kozai, T.1    Eto, M.2    Yang, Z.3    Shimokawa, H.4    Luscher, T.F.5
  • 16
    • 0032584177 scopus 로고    scopus 로고
    • Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors
    • U. Laufs, V. La Fata, J. Plutzky, and J.K. Liao Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors Circulation 1998 1129 1135 (Pubitemid 28152885)
    • (1998) Circulation , vol.97 , Issue.12 , pp. 1129-1135
    • Laufs, U.1    La Fata, V.2    Plutzky, J.3    Liao, J.K.4
  • 17
    • 0035133978 scopus 로고    scopus 로고
    • Direct measurement of nitric oxide release from saphenous vein: Abolishment by surgical preparation
    • DOI 10.1016/S0003-4975(00)02231-1, PII S0003497500022311
    • Z.G. Liu, X.C. Liu, A.P. Yim, and G.W. He Direct measurement of nitric oxide release from saphenous vein: abolishment by surgical preparation Ann. Thorac. Surg. 71 2001 133 137 (Pubitemid 32102647)
    • (2001) Annals of Thoracic Surgery , vol.71 , Issue.1 , pp. 133-137
    • Liu, Z.-G.1    Liu, X.-C.2    Yim, A.P.C.3    He, G.-W.4
  • 18
    • 33748149718 scopus 로고    scopus 로고
    • Internal mammary artery smooth muscle cells resist migration and possess high antioxidant capacity
    • DOI 10.1016/j.cardiores.2006.06.022, PII S000863630600294X
    • V.S. Mahadevan, M. Campbell, P.P. McKeown, and U. Bayraktutan Internal mammary artery smooth muscle cells resist migration and possess high antioxidant capacity Cardiovasc. Res. 72 2006 60 68 (Pubitemid 44429903)
    • (2006) Cardiovascular Research , vol.72 , Issue.1 , pp. 60-68
    • Mahadevan, V.S.1    Campbell, M.2    McKeown, P.P.3    Bayraktutan, U.4
  • 19
    • 76749152023 scopus 로고    scopus 로고
    • Beneficial microvascular and anti-inflammatory effects of pravastatin during sepsis involve nitric oxide synthase III
    • C.C. McGown, N.J. Brown, P.G. Hellewell, C.S. Reilly, and Z.L. Brookes Beneficial microvascular and anti-inflammatory effects of pravastatin during sepsis involve nitric oxide synthase III Br. J. Anaesth. 104 2010 183 190
    • (2010) Br. J. Anaesth. , vol.104 , pp. 183-190
    • McGown, C.C.1    Brown, N.J.2    Hellewell, P.G.3    Reilly, C.S.4    Brookes, Z.L.5
  • 20
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology, and pharmacology
    • S. Moncada, R.M. Palmer, and E.A. Higgs Nitric oxide: physiology, pathophysiology, and pharmacology Pharmacol. Rev. 43 1991 109 142
    • (1991) Pharmacol. Rev. , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.2    Higgs, E.A.3
  • 22
    • 33747033675 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitor fluvastatin prevents angiotensin II-induced cardiac hypertrophy via Rho kinase and inhibition of cyclin D1
    • DOI 10.1016/j.lfs.2006.04.005, PII S0024320506003304
    • K. Morikawa-Futamatsu, S. Adachi, Y. Maejima, M. Tamamori-Adachi, J. Suzuki, S. Kitajima, H. Ito, and M. Isobe HMG-CoA reductase inhibitor fluvastatin prevents angiotensin II-induced cardiac hypertrophy via Rho kinase and inhibition of cyclin D1 Life Sci. 79 2006 1380 1390 (Pubitemid 44215930)
    • (2006) Life Sciences , vol.79 , Issue.14 , pp. 1380-1390
    • Morikawa-Futamatsu, K.1    Adachi, S.2    Maejima, Y.3    Tamamori-Adachi, M.4    Suzuki, J.-i.5    Kitajima, S.6    Ito, H.7    Isobe, M.8
  • 24
    • 1342289577 scopus 로고    scopus 로고
    • Lovastatin inhibits Rho-regulated expression of E-selectin by TNFα and attenuates tumor cell adhesion
    • T. Nübel, W. Dippold, H. Kleinert, B. Kaina, and G. Fritz Lovastatin inhibits Rho-regulated expression of E-selectin by TNFα and attenuates tumor cell adhesion FASEB 18 2004 140 142
    • (2004) FASEB , vol.18 , pp. 140-142
    • Nübel, T.1    Dippold, W.2    Kleinert, H.3    Kaina, B.4    Fritz, G.5
  • 25
    • 0031032831 scopus 로고    scopus 로고
    • Simvastatin, an HMG-coenzyme A reductase inhibitor, improves endothelial function within 1 month
    • G. O'Driscoll, D. Green, and R.R. Taylor Simvastatin, an HMG-coenzyme A reductase inhibitor, improves endothelial function within 1 month Circulation 95 1997 1126 1131 (Pubitemid 27097821)
    • (1997) Circulation , vol.95 , Issue.5 , pp. 1126-1131
    • O'Driscoll, G.1    Green, D.2    Taylor, R.R.3
  • 26
    • 33644694919 scopus 로고    scopus 로고
    • Rho GTPases, statins and nitric oxide
    • Y. Rikitake, and J.K. Liao Rho GTPases, statins and nitric oxide Circ. Res. 97 2005 1232 1235
    • (2005) Circ. Res. , vol.97 , pp. 1232-1235
    • Rikitake, Y.1    Liao, J.K.2
  • 28
    • 13244278134 scopus 로고    scopus 로고
    • Comparison of saphenous vein and internal thoracic artery graft patency by coronary system
    • DOI 10.1016/j.athoracsur.2004.07.047, PII S000349750401611X
    • J.F. SabIk, B.W. Lytle, E.H. Blackstone, P.L. Houghtaling, and D.M. Cosgrove Comparison of saphenous vein and internal thoracic artery graft patency by coronary system Ann. Thorac. Surg. 79 2005 544 551 (Pubitemid 40186555)
    • (2005) Annals of Thoracic Surgery , vol.79 , Issue.2 , pp. 544-551
    • Sabik III, J.F.1    Lytle, B.W.2    Blackstone, E.H.3    Houghtaling, P.L.4    Cosgrove, D.M.5
  • 29
    • 0036768788 scopus 로고    scopus 로고
    • Mechanisms and future directions for prevention of vein graft failure in coronary bypass surgery
    • DOI 10.1016/S1010-7940(02)00253-1, PII S1010794002002531
    • J.H. Shuhaiber, A.N. Evans, M.G. Massad, and A.S. Geha Mechanisms and future directions for prevention of vein graft failure in coronary bypass surgery Eur. J. Cardiothorac. Surg. 22 2002 387 396 (Pubitemid 36157379)
    • (2002) European Journal of Cardio-thoracic Surgery , vol.22 , Issue.3 , pp. 387-396
    • Shuhaiber, J.H.1    Evans, A.N.2    Massad, M.G.3    Geha, A.S.4
  • 30
    • 0020538799 scopus 로고
    • Ultrastructure of human and transplanted canine veins: Effects of different preparation media
    • V.S. Sottiurai, J.C. Stanley, and W.J. Fry Ultrastructure of human and transplanted canine veins: effects of different preparation media Surgery 93 1983 128 138
    • (1983) Surgery , vol.93 , pp. 128-138
    • Sottiurai, V.S.1    Stanley, J.C.2    Fry, W.J.3
  • 31
    • 0036645303 scopus 로고    scopus 로고
    • Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase
    • DOI 10.1161/01.CIR.0000020682.73694.AB
    • M. Takemoto, J. Sun, J. Hiroki, H. Shimokawa, and J.K. Liao Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase Circulation 106 2002 57 62 (Pubitemid 34747442)
    • (2002) Circulation , vol.106 , Issue.1 , pp. 57-62
    • Takemoto, M.1    Sun, J.2    Hiroki, J.3    Shimokawa, H.4    Liao, J.K.5
  • 32
    • 0036482335 scopus 로고    scopus 로고
    • Localization of nitric oxide synthase in saphenous vein grafts havested with a novel "no-touch" technique: Potential role of nitric oxide contribution to improved early graft patency rates
    • DOI 10.1067/mva.2002.121072
    • J.C. Tsui, D.S. Souza, D. Filbey, M.G. Karlsson, and M.R. Dashwood Localization of nitric oxide synthase in saphenous vein grafts harvested with a novel "no-touch" technique: potential role of nitric oxide contribution to improved early graft patency rates J. Vasc. Surg. 35 2002 356 362 (Pubitemid 44718645)
    • (2002) Journal of Vascular Surgery , vol.35 , Issue.2 , pp. 356-362
    • Tsui, J.C.S.1    Souza, D.S.R.2    Filbey, D.3    Karlsson, M.G.4    Dashwood, M.R.5
  • 33
    • 38049034068 scopus 로고    scopus 로고
    • Pleiotropic effects of statin therapy: Molecular mechanisms and clinical results
    • C.Y. Wang, P.Y. Liu, and J.K. Liao Pleiotropic effects of statin therapy: molecular mechanisms and clinical results Trends Mol. Med. 14 2008 37 44
    • (2008) Trends Mol. Med. , vol.14 , pp. 37-44
    • Wang, C.Y.1    Liu, P.Y.2    Liao, J.K.3
  • 34
    • 0035569562 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors improve endothelial dysfunction in normocholesterolemic hypertension via reduced production of reactive oxygen species
    • S. Wassmann, U. Laufs, A.T. Bäumer, K. Müller, K. Ahlbory, W. Linz, G. Itter, R. Rösen, M. Böhm, and G. Nickenig HMG-CoA reductase inhibitors improve endothelial dysfunction in normocholesterolemic hypertension via reduced production of reactive oxygen species Hypertension 37 2001 1450 1457 (Pubitemid 34225391)
    • (2001) Hypertension , vol.37 , Issue.6 , pp. 1450-1457
    • Wassmann, S.1    Laufs, U.2    Baumer, A.T.3    Muller, K.4    Ahlbory, K.5    Linz, W.6    Itter, G.7    Rosen, R.8    Bohm, M.9    Nickenig, G.10


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