In vitro inhibition of human and rat platelets by NO donors, nitrosoglutathione, sodium nitroprusside and SIN-1, through activation of cGMP-independent pathways

Pharmacological Research

Volumn 64, Issue 3, 2011, Pages 289-297

  Priora, Raffaella ^a   Margaritis, Antonios ^a   Frosali, Simona ^a   Coppo, Lucia ^a   Summa, Domenico ^b   Di Giuseppe, Danila ^a   Aldinucci, Carlo ^a   Pessina, Gianpaolo ^a   Di Stefano, Anna ^a   Di Simplicio, Paolo ^a  

^a UNIVERSITY OF SIENA   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

cGMP independent response; GSNO; Platelets; Protein sulfhydryl groups (PSH); SIN 1; Sodium nitroprusside

Indexed keywords

CYCLIC GMP; FIBRINOGEN RECEPTOR; LINSIDOMINE; NITRIC OXIDE; NITROPRUSSIDE SODIUM; S NITROSOGLUTATHIONE;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG MECHANISM; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; NITROSYLATION; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; RAT; THROMBOCYTE AGGREGATION; THROMBOCYTE AGGREGATION INHIBITION; THROMBOCYTE RICH PLASMA;

ANIMALS; BLOOD PLATELETS; CYCLIC GMP; HUMANS; MALE; MOLSIDOMINE; NITRIC OXIDE DONORS; NITROPRUSSIDE; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PROTEIN CONFORMATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, FIBRINOGEN; S-NITROSOGLUTATHIONE;

EID: 79960021199     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2011.03.014     Document Type: Article

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