Inhibition of platelet aggregation by S-nitroso-cysteine via cGMP-independent mechanisms: Evidence of inhibition of thromboxane A2 synthesis in human blood platelets

FEBS Letters

Volumn 442, Issue 2-3, 1999, Pages 162-166

  Tsikas, Dimitrios ^a   Ikic, Milos ^a   Tewes, Kathrin S ^a   Raida, Manfred ^b   Frölich, Jürgen C ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b IPF PHARMACEUTICALS GMBH   (Germany)

Author keywords

1H 1,2,4 Oxadiazolo 4,3 a quinoxalin 1 one; Aggregation; cGMP; S Nitroso L cysteine; S Nitrosylation; SQ 29548

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 7 [3 [(4 PHENYLSEMICARBAZIDO)METHYL] 7 OXABICYCLO[2.2.1]HEPT 2 YL] 5 HEPTENOIC ACID; ARACHIDONIC ACID; COLLAGEN; CYCLIC GMP; S NITROSOCYSTEINE; THROMBOXANE A2; THROMBOXANE A2 RECEPTOR BLOCKING AGENT;

ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; HUMAN; HUMAN CELL; NITROSATION; PRIORITY JOURNAL; THROMBOCYTE AGGREGATION; THROMBOCYTE MEMBRANE;

ARACHIDONIC ACID; ASPIRIN; BLOOD PLATELETS; COLLAGEN; CYCLIC GMP; CYSTEINE; GLUTATHIONE; GUANYLATE CYCLASE; HUMANS; HYDRAZINES; INHIBITORY CONCENTRATION 50; NITRIC OXIDE; NITRITES; NITROPRUSSIDE; NITROSO COMPOUNDS; OXADIAZOLES; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; QUINOXALINES; S-NITROSOGLUTATHIONE; S-NITROSOTHIOLS; THROMBOXANE A2;

EID: 0032955272     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(98)01633-0     Document Type: Article

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