Melatonin independent protective role of l-tryptophan in experimental reflux esophagitis in rats

Pharmacological Research

Volumn 64, Issue 3, 2011, Pages 249-257

  Singh, Pratibha ^a   Singh, Neetu ^a   Ahmad, Ausaf ^a,b   Singh, Omprakash ^a   Palit, Gautam ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b AMITY UNIVERSITY   (India)

Author keywords

Arylalkylamine N acetyltransferase; Gastroesophageal reflux disorder; l Tryptophan; Melatonin; PGE2

Indexed keywords

ACETYLSEROTONIN METHYLTRANSFERASE; ARALKYLAMINE ACETYLTRANSFERASE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; MELATONIN; OMEPRAZOLE; PROSTAGLANDIN E2; STOMACH MUCIN; TRYPTOPHAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; GENE EXPRESSION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REFLUX ESOPHAGITIS; STOMACH PH; STOMACH SECRETION;

ACETYLSEROTONIN O-METHYLTRANSFERASE; ANIMALS; ARYLALKYLAMINE N-ACETYLTRANSFERASE; DINOPROSTONE; ESOPHAGITIS, PEPTIC; ESOPHAGUS; GENE EXPRESSION REGULATION; MELATONIN; PROTON-TRANSLOCATING ATPASES; RATS; RATS, SPRAGUE-DAWLEY; SODIUM-POTASSIUM-EXCHANGING ATPASE; TRYPTOPHAN;

EID: 79960013354     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2011.04.004     Document Type: Article

References (47)

1. J. Dent, H.B. El-Serag, M.A. Wallander, and S. Johansson Epidemiology of gastro-oesophageal reflux disease: a systematic review Gut 54 2005 710 717 (Pubitemid 40559260)
2. J. Lagergren, R. Bergstrom, A. Lindgren, and O. Nyren Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma N Engl J Med 340 1999 825 831 (Pubitemid 29142625)
3. P.O. Katz Optimizing medical therapy for gastroesophageal reflux disease: state of the art Rev Gastroenterol Disord 3 2003 59 69 (Pubitemid 36701287)
4. S. Pereira Rde Regression of gastroesophageal reflux disease symptoms using dietary supplementation with melatonin, vitamins and aminoacids: comparison with omeprazole J Pineal Res 41 2006 195 200
5. S.J. Konturek, O. Zayachkivska, X.O. Havryluk, T. Brzozowski, Z. Sliwowski, and M. Pawlik Protective influence of melatonin against acute esophageal lesions involves prostaglandins, nitric oxide and sensory nerves J Physiol Pharmacol 58 2007 361 377 (Pubitemid 47026568)
6. T.S. Kandil, A.A. Mousa, A.A. El-Gendy, and A.M. Abbas The potential therapeutic effect of melatonin in gastro-esophageal reflux disease BMC Gastroenterol 10 2010 7
7. G. Klupinska, M. Wisniewska-Jarosinska, A. Harasiuk, C. Chojnacki, K. Stec-Michalska, and J. Blasiak Nocturnal secretion of melatonin in patients with upper digestive tract disorders J Physiol Pharmacol 57 Suppl. 5 2006 41 50 (Pubitemid 46569783)
8. A. Lerner, J. Case, and J. Takahashi Isolation of melatonin, the pineal glan factor that ligghtens melanocytes J Am Chem Soc 80 1958 2587 2589
9. I.M. Kvetnoy Extrapineal melatonin: location and role within diffuse neuroendocrine system Histochem J 31 1999 1 12 (Pubitemid 29294785)
10. G. Huether The contribution of extrapineal sites of melatonin synthesis to circulating melatonin levels in higher vertebrates Experientia 49 1993 665 670 (Pubitemid 23256792)
11. N.T. Raikhlin, I.M. Kvetnoy, and V.N. Tolkachev Melatonin may be synthesised in enterochromaffin cells Nature 255 1975 344 345
12. W. Quay, and Y. Ma Demonstration of gastrointestinal hydroxyindole-o- methyl transferase IRCS Med Sci 4 1976 563
13. D. Sugden Melatonin biosynthesis in the mammalian pineal gland Experientia 45 1989 922 932 (Pubitemid 19254804)
14. G. Huether, B. Poeggeler, A. Reimer, and A. George Effect of tryptophan administration on circulating melatonin levels in chicks and rats: evidence for stimulation of melatonin synthesis and release in the gastrointestinal tract Life Sci 51 1992 945 953
15. K. Yaga, R.J. Reiter, and B.A. Richardson Tryptophan loading increases daytime serum melatonin levels in intact and pinealectomized rats Life Sci 52 1993 1231 1238
16. T. Brzozowski, P.C. Konturek, S.J. Konturek, R. Pajdo, W. Bielanski, and I. Brzozowska The role of melatonin and l-tryptophan in prevention of acute gastric lesions induced by stress, ethanol, ischemia, and aspirin J Pineal Res 23 1997 79 89 (Pubitemid 127731742)
17. N. Bulbuller, B. Pektas, A. Ozdarendeli, O. Dogru, E. Aygen, and N. Akpolat The effect of l-tryptophan on hemorrhagic shock induced bacterial translocation J Surg Res 123 2005 194 199 (Pubitemid 40186897)
18. K. Nakamura, Y. Ozawa, Y. Furuta, and H. Miyazaki Effects of sodium polyacrylate (PANa) on acute esophagitis by gastric juice in rats Jpn J Pharmacol 32 1982 445 456 (Pubitemid 12082389)
19. C.V. Rao, and M. Vijayakumar Effect of quercetin, flavonoids and alpha-tocopherol, an antioxidant vitamin, on experimental reflux oesophagitis in rats Eur J Pharmacol 589 2008 233 238
20. T. Hayakawa, Y. Fujiwara, M. Hamaguchi, T. Sugawa, M. Okuyama, and E. Sasaki Roles of cyclooxygenase 2 and microsomal prostaglandin E synthase 1 in rat acid reflux oesophagitis Gut 55 2006 450 456
21. Y. Sagara, Y. Okatani, S. Yamanaka, and T. Kiriyama Determination of plasma 5-hydroxytryptophan, 5-hydroxytryptamine, 5-hydroxyindoleacetic acid, tryptophan and melatonin by high-performance liquid chromatography with electrochemical detection J Chromatogr 431 1988 170 176
22. P.C. Konturek, S.J. Konturek, G. Burnat, T. Brzozowski, I. Brzozowska, and R.J. Reiter Dynamic physiological and molecular changes in gastric ulcer healing achieved by melatonin and its precursor l-tryptophan in rats J Pineal Res 45 2008 180 190
23. R.S. Crowther, and R.F. Wetmore Fluorometric assay of O-linked glycoproteins by reaction with 2-cyanoacetamide Anal Biochem 163 1987 170 174 (Pubitemid 17087569)
24. W.W. Reenstra, and J.G. Forte Isolation of H+,K(+)-ATPase-containing membranes from the gastric oxyntic cell Methods Enzymol 192 1990 151 165
25. H. Sanui Measurement of inorganic orthophosphate in biological materials: extraction properties of butyl acetate Anal Biochem 60 1974 489 504
26. O.H. Lowry, N.J. Rosebrough, A.L. Farr, and R.J. Randall Protein measurement with the Folin phenol reagent J Biol Chem 193 1951 265 275
27. G.A. Bubenik Localization of melatonin in the digestive tract of the rat. Effect of maturation, diurnal variation, melatonin treatment and pinealectomy Horm Res 12 1980 313 323 (Pubitemid 10056524)
28. S. Esteban, C. Nicolaus, A. Garmundi, R.V. Rial, A.B. Rodriguez, and E. Ortega Effect of orally administered l-tryptophan on serotonin, melatonin, and the innate immune response in the rat Mol Cell Biochem 267 2004 39 46 (Pubitemid 39562383)
29. G. Hajak, G. Huether, J. Blanke, M. Blomer, C. Freyer, and B. Poeggeler The influence of intravenous l-tryptophan on plasma melatonin and sleep in men Pharmacopsychiatry 24 1991 17 20
30. R.J. Wurtman, and F. Anton-Tay The mammalian pineal as a neuroendocrine transducer Recent Prog Horm Res 25 1969 493 522
31. M. Ikeda, H. Tsuji, S. Nakamura, A. Ichiyama, Y. Nishizuka, and O. Hayaishi Studies on the biosynthesis of nicotinamide adenine dinucleotide. II. A role of picolinic carboxylase in the biosynthesis of nicotinamide adenine dinucleotide from tryptophan in mammals J Biol Chem 240 1965 1395 1401
32. K. Schrocksnadel, B. Wirleitner, C. Winkler, and D. Fuchs Monitoring tryptophan metabolism in chronic immune activation Clin Chim Acta 364 2006 82 90 (Pubitemid 43120630)
33. N. Yoshida Inflammation and oxidative stress in gastroesophageal reflux disease J Clin Biochem Nutr 40 2007 13 23 (Pubitemid 46449683)
34. G.A. Bubenik, G.M. Brown, and L.J. Grota Immunohistological localization of melatonin in the rat digestive system Experientia 33 1977 662 663 (Pubitemid 8094289)
35. R.J. Reiter Neuroendocrine effects of light Int J Biometeorol 35 1991 169 175
36. D.C. Klein, S.L. Coon, P.H. Roseboom, J.L. Weller, M. Bernard, and J.A. Gastel The melatonin rhythm-generating enzyme: molecular regulation of serotonin N-acetyltransferase in the pineal gland Recent Prog Horm Res 52 1997 307 357 [Discussion 57-58] (Pubitemid 127470216)
37. J.A. Gastel, P.H. Roseboom, P.A. Rinaldi, J.L. Weller, and D.C. Klein Melatonin production: proteasomal proteolysis in serotonin N-acetyltransferase regulation Science 279 1998 1358 1360 (Pubitemid 28119578)
38. K.M. Harnett, W. Cao, N. Kim, U.D. Sohn, H. Rich, and J. Behar Signal transduction in esophageal and LES circular muscle contraction Yale J Biol Med 72 1999 153 168 (Pubitemid 30215115)
39. C. Schomerus, E. Laedtke, J. Olcese, J.L. Weller, D.C. Klein, and H.W. Korf Signal transduction and regulation of melatonin synthesis in bovine pinealocytes: impact of adrenergic, peptidergic and cholinergic stimuli Cell Tissue Res 309 2002 417 428 (Pubitemid 34994879)
40. A. Allen, G. Flemstrom, A. Garner, and E. Kivilaakso Gastroduodenal mucosal protection Physiol Rev 73 1993 823 857 (Pubitemid 24004654)
41. A. Allen, and A. Garner Mucus and bicarbonate secretion in the stomach and their possible role in mucosal protection Gut 21 1980 249 262 (Pubitemid 10082938)
42. I.P. Pavlov Lectures on the work of the digestive glands 1910 Charles Griffin and Co. London
43. H. Larsson, E. Carlsson, U. Junggren, L. Olbe, S.E. Sjostrand, and I. Skanberg Inhibition of gastric acid secretion by omeprazole in the dog and rat Gastroenterology 85 1983 900 907 (Pubitemid 13000644)
44. M. Sababi, E. Nilsson, and L. Holm Mucus and alkali secretion in the rat duodenum: effects of indomethacin, N omega-nitro-l-arginine, and luminal acid Gastroenterology 109 1995 1526 1534
45. C. Johansson, and B. Kollberg Effects of E2 prostaglandins on gastric secretion and gastrointestinal mucosa Scand J Gastroenterol Suppl 58 1980 93 97 (Pubitemid 10064068)
46. M. Ding, Y. Kinoshita, K. Kishi, H. Nakata, S. Hassan, and C. Kawanami Distribution of prostaglandin E receptors in the rat gastrointestinal tract Prostaglandins 53 1997 199 216 (Pubitemid 27187728)
47. S. Tani, M. Okuda, R. Morishige, and T. Tanaka Gastric mucin secretion from cultured rat epithelial cells Biol Pharm Bull 20 1997 482 485 (Pubitemid 27250630)