CD10 and ICOS expression by multiparametric flow cytometry in angioimmunoblastic T-cell lymphoma

Modern Pathology

Volumn 24, Issue 7, 2011, Pages 993-1003

  Baseggio, Lucile ^a,b   Traverse Glehen, Alexandra ^a,b   Berger, Françoise ^a,b   Ffrench, Martine ^a,b   Jallades, Laurent ^a,b   Morel, Dominique ^a,b   Goedert, Ghislaine ^a,b   Magaud, Jean Pierre ^a,b   Salles, Gilles ^a,b   Felman, Pascale ^a,b  

^a CENTRE HOSPITALIER LYON SUD   (France)

^b UNIVERSITÉ DE LYON   (France)

Author keywords

angioimmunoblastic T cell lymphoma; CD10; circulating neoplastic T cells; ICOS; multiparametric flow cytometry; PD 1

Indexed keywords

COMMON ACUTE LYMPHOBLASTIC LEUKEMIA ANTIGEN; INDUCIBLE T CELL COSTIMULATOR PROTEIN; PROGRAMMED DEATH 1 RECEPTOR; TUMOR MARKER; UNCLASSIFIED DRUG;

ADULT; AGED; ANGIOIMMUNOBLASTIC T CELL LYMPHOMA; ANTIGEN EXPRESSION; ARTICLE; BLOOD; CANCER DIAGNOSIS; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; HUMAN; HYPERPLASIA; LYMPH NODE; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; T CELL LYMPHOMA;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; APOPTOSIS REGULATORY PROTEINS; CELL SEPARATION; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOBLASTIC LYMPHADENOPATHY; LYMPH NODES; LYMPHOMA, T-CELL; MALE; MIDDLE AGED; NEOPLASTIC CELLS, CIRCULATING; NEPRILYSIN; TUMOR MARKERS, BIOLOGICAL;

EID: 79960005544     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.2011.53     Document Type: Article

References (27)

1. A clinical evaluation of the International Lymphoma Study Group classification of non-Hodgkin's lymphoma: by the Non-Hodgkin's Lymphoma Classification Project. Blood 1997;89:3909-3918.
2. Dogan A, Gaulard P, Jaffe E, et al. Angioimmunoblastic T-cell lymphoma. In: Swerdlow SH, Campo E, Harris NL et al. (eds). World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues, 4th edn. IARC Press: Lyon, 2008, pp 309-311.
3. Vose J, Armitage J, Weisenburger D, International TCell Lymphoma Project. International peripheral T-cell and natural killer/T-cell lymphoma study: pathology findings and clinical outcomes. J Clin Oncol 2008;26:4124-4130.
4. Mourad N, Mounier N, Brière J, , et al., Groupe d'Etude des Lymphomes de l'Adulte. Clinical, biologic, and pathologic features in 157 patients with angioimmunoblastic T-cell lymphoma treated within the Groupe d'Etude des Lymphomes de l'Adulte (GELA) trials. Blood 2008;111:4463-4467.
5. Attygalle A, Al-Jehani R, Diss TC, et al. Neoplastic T cells in angioimmunoblastic T-cell lymphoma express CD10. Blood 2002;99:627-633. (Pubitemid 34533101)
6. Attygalle AD, Diss TC, Munson P, et al. CD10 expression in extranodal dissemination of angioimmunoblastic T-cell lymphoma. Am J Surg Pathol 2004; 28:54-61. (Pubitemid 38031621)
7. Baseggio L, Berger F, Morel D, et al. Identification of circulating CD10 positive T cells in angioimmunoblastic T-cell lymphoma. Leukemia 2006;20:296-303. (Pubitemid 43148668)
8. Lee SS, Rudiger T, Odenwald T, et al. Angioimmunoblastic T cell lymphoma is derived from mature Thelper cells with varying expression and loss of detectable CD4. Int J Cancer 2003;103:12-20. (Pubitemid 35424200)
9. Dorfman DM, Brown JA, ShaHsafaei A, et al. Programmed death-1 (PD-1) is a marker of germinal centerassociated T cells and angio-immunoblastic T-cell lymphoma. Am J Surg Pathol 2006;30:802-810. (Pubitemid 44264969)
10. de Leval L, Rickman DS, Thielen C, et al. The gene expression profile of nodal peripheral T-cell lymphoma demonstrates a molecular link between angioimmunoblastic T-cell lymphoma (AITL) and follicular helper T (TFH) cells. Blood 2007;109:4952-4963. (Pubitemid 46827794)
11. Piccaluga PP, Agostinelli C, Califano A, et al. Gene expression analysis of angioimmunoblastic lymphoma indicates derivation from T follicular helper cells and vascular endothelial growth factor deregulation. Cancer Res 2007;67:10703-10710. (Pubitemid 350145896)
12. Grogg KL, Attygalle AD, Macon WR, et al. Expression of CXCL13, a chemokine highly upregulated in germinal center T-helper cells, distinguishes angioimmunoblastic T-cell lymphoma from peripheral T-cell lymphoma, unspecified. Mod Pathol 2006;19: 1101-1107. (Pubitemid 44106725)
13. Dupuis J, Boye K, Martin N, et al. Expression of CXCL13 by neoplastic cells in angioimmunoblastic Tcell lymphoma (AITL): a new diagnostic marker providing evidence that AITL derives from follicular helper T cells. Am J Surg Pathol 2006;30:490-494. (Pubitemid 43740150)
14. Krenacs L, Schaerli P, Kis G, et al. Phenotype of neoplastic cells in angioimmunoblastic T-cell lymphoma is consistent with activated follicular B helper T cells. Blood 2006;108:1110-1111. (Pubitemid 44154657)
15. Roncador G, Garc?́a Verdes-Montenegro JF, Tedoldi S, et al. Expression of two markers of germinal center T cells (SAP and PD-1) in angioimmunoblastic T-cell lymphoma. Haematologica 2007;92:1059-1066. (Pubitemid 350144212)
16. Rodriguez-Justo M, Attygalle AD, Munson P, et al. Angioimmunoblastic T-cell lymphoma with hyperplastic germinal centres: a neoplasia with origin in the outer zone of the germinal centre? Clinicopathological and immunohistochemical study of 10 cases with follicular T-cell markers. Mod Pathol 2009;22:753-761.
17. Marafioti T, Paterson JC, Ballabio E, et al. The inducible T-cell co-stimulator molecule is expressed on subsets of T cells and is a new marker of lymphomas of T follicular helper cell-derivation. Haematologica 2010;95:432-439.
18. Serke S, van Lessen A, Hummel M, et al. Circulating CD4+ T lymphocytes with intracellular but no surface CD3 antigen in five of seven patients consecutively diagnosed with angioimmunoblastic T-cell lymphoma. Cytometry 2000;42:180-187. (Pubitemid 30451718)
19. Diaz-Alderete A, Menarguez J, Alvarez-Doval A, et al. Lymphocyte immunophenotype of circulating angioimmunoblastic T-cell lymphoma cells. Br J Haematol 2006;134:347-348. (Pubitemid 43990804)
20. Theodorou I, Bigorgne C, Delfau MH, et al. VJ rearrangements of the TCR locus in peripheral T-cell lymphomas: analysis by polymerase chain reaction and denaturing gradient gel electrophoresis. J Pathol 1996;178:303-310.
21. van Dongen JJ, Langerak AW, Bruggemann M, et al. Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936. Leukemia 2003;7: 2257-2317. (Pubitemid 38072572)
22. Rawstron AC, Villamor N, Ritgen M, et al. International standardized approach for flow cytometric residual disease monitoring in chronic lymphocytic leukaemia. Leukemia 2007;21:956-964. (Pubitemid 46672072)
23. San-Miguel JF, Vidriales MB, Orfão A. Immunological evaluation of minimal residual disease (MRD) in acute myeloid leukaemia (AML). Best Pract Res Clin Haematol 2002;15:105-118.
24. Schaerli P, Willimann K, Lang AB, et al. CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function. J Exp Med 2000;192:1553-1562.
25. Breitfeld D, Ohl L, Kremmer E, et al. Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production. J Exp Med 2000;192:1545-1552.
26. Lim HW, Kim CH. Loss of IL-7 receptor alpha on CD4+ T cells defines terminally differentiated B cell-helping effector T cells in a B cell-rich lymphoid tissue. J Immunol 2007;179:7448-7456.
27. Chtanova T, Tangye SG, Newton R, et al. T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells. J Immunol 2004; 173:68-78. (Pubitemid 38797327)