VJ rearrangements of the TCRy locus in peripheral T-cell lymphomas: Analysis by polymerase chain reaction and denaturing gradient gel electrophoresis

Journal of Pathology

Volumn 178, Issue 3, 1996, Pages 303-310

  Theodorou, Ioannis ^a   Bigorgne, Claude ^a   Delfau, Marie Hélène ^a   Lahet, Chantal ^a   Cochet, Gilles ^a   Vidaud, Michel ^b   Raphael, Martine ^c   Gaulard, Philippe ^a   Farcet, Jean Pierre ^a  

^a HENRI MONDOR HOSPITAL   (France)

^b CNRS   (France)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

Clonality; PCR; Peripheral T cell lymphoma; T cell receptor; Y locus

Indexed keywords

T LYMPHOCYTE RECEPTOR;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ELECTROPHORESIS; GENE REARRANGEMENT; HUMAN; HUMAN TISSUE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; T CELL LYMPHOMA;

BASE SEQUENCE; BLOTTING, SOUTHERN; DNA PRIMERS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENE REARRANGEMENT, GAMMA-CHAIN T-CELL ANTIGEN RECEPTOR; GENETIC MARKERS; HUMANS; LYMPHOMA, T-CELL, PERIPHERAL; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY;

EID: 0029670414     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1096-9896(199603)178:3<303::aid-path475>3.0.co;2-i     Document Type: Article

References (35)

1. Flug F, Pelieei PG, Bonetti F, Knowles DM, Dalla-Favera R. T-cell receptor gene rearrangements as markers of lineage and clonality in T-cell neoplasms. Proc Natl Acad Sci USA 1988; 82: 3460-3464.
2. Bertness V, Kirsh I, Hillis G, Johnson B, Bunn PA T-cell receptor gene rearrangements as clinical markers of human T-cell lymphomas. N Engl J Med 1985; 313: 535-538.
3. O'Connor NTJ, Wainscoat JS, Weatherall DJ, et al. Rearrangement of the T-cell receptor β-chain gene in the diagnosis of lymphoproliferative disorders. Lancet 1985; 1: 1295-1297.
4. Waldmann TA, Davis MM, Bongiovanni KF, Korsmeyer SJ Rearrangements of genes for the antigen receptor on T cells as markers of lineage and clonality in human lymphoid neoplasms. N Engl J Med 1985; 313: 776-783.
5. Williams ME, Innes DJ, Borowitz M, et al. Immunoglobulin and T cell receptor gene rearrangements in human lymphoma and leukemia. Blood 1987; 69: 79-86.
6. Minden MD, Toyonoga B, Ha Y, et al. Somatic rearrangement of T-cell antigen receptor gene in human T-ceH malignancies. Proc Natl Acad Sci USA 1985; 82: 1224-1228.
7. Aisenberg AC. Utility of gene rearrangements in lymphoid malignancies. Annu Rev Med 1993; 44: 75-84
8. Picker L, Brenner M, Weiss L, Smith S, Warnke R. Discordant expression of CD3 and TCR β-chain antigens in T lineage lymphomas. Am J Pathol 1987; 129: 434-440.
9. Gaulard P, Bourquelot P, Kanavaros P. Expression of the αβ and γδ T-cell receptors in 57 cases of peripheral T-cell lymphoma. Am J Pathol 1990; 137: 617-623.
10. Theodorou I, Raphael M, Bigorgne C, et al. Recombination pattern of the TCR γ locus in human peripheral T cell lymphomas J Pathol 1994; 174: 233-242.
11. Kanavaros P, Farcet JP, Gaulard P. Recombmative events of the T cell antigen receptor delta gene in peripheral T cell iymphomas. J Clm Invest 1991; 87: 666-672
12. Lefranc MP, Chuchana P, Dariavach P, et al. Molecular mapping of the human T cell receptor gamma (TRG) genes and linkage of the variable and constant regions. Eur J Immunol 1989; 19: 989-994.
13. Quetermous T. Strauss W, Murre C, Dialynas DP, Strominger JL, Seidman JG Human T-cell γ genes contain N segments and have marked junctional variability. Nature 1986: 322: 184-197
14. Bottaro M. Berti E, Biondi A, Migone N, Crosti L. Heteroduplex analysis of T-cell receptor γ gene rearrangements for diagnosis and monitoring of cutaneous T-cell lymphomas. Blood 1994; 11: 3271-3276.
15. Kneba M, Bolz I, Linke B, Bertram J, Rothaupt D, Hiddemann W Characterization of clone-specific rearranged T-cell receptor y-chain genes in lymphomas and leukemias by the polymerase chain reaction and DNA sequencing. Blood 1994; 84: 574-581.
16. Fischer SG, Lerman LS. DNA fragments differing by single base-pair substitutions are separated in denaturing gradient gels: correspondence with melting theory. Proc Natl Acad Sci USA 1983; 80: 1579-1583.
17. Sheffield V, Cox D, Lerman L, Myers R. Attachment of a 40-base-pair G + C-rich sequence (GC-clamp) to genomic DNA fragments by the polymerase chain reaction results in improved detection of single-base changes. Proc Natl Acad Sci USA 1989; 86: 232-236.
18. Bourguin A, Tung R, Galili N, Sklar RJ Rapid, nonradioactive detection of clonal T-cell receptor gene rearrangements in lymphoid neoplasms Proc Nail Acad Sci USA 1990; 87: 8536-8540.
19. Macintyre E, D'Auriol L, Duparc N, Leverger G, Gahbert F, Sigaux F. Use of ohgonucleotide probes directed against T cell antigen receptor gamma delta variable-; (diversity)-joining junctional sequences as a general method for detecting minimal residual disease in acute lymphoblastic leukemias J Clin Invest 1990; 86: 2125-2135
20. Trainor K, Brisco M, Wan J, Neoh S, Grist S, Morley A. Gene rearrangement in B- and T-lymphoprohferative disease detected by the polymerase chain reaction. Blood 1991; 78: 192-196.
21. Longo MC, Berninger MS, Hartley JL. The use of Uracil DNA glycosylase to control carryover contamination in polymerase chain reactions. Gene 1990; 93: 125-130.
22. Myers RM, Maniatis T, Lerman LS. Detection and localization of single base changes by denaturing gradient gel electrophoresis. Methods Enzymol 1987; 155: 501-525.
23. Huck S, Lefranc MP. Rearrangements to the JP1, JP and JP2 segments m the human T-cell rearranging gamma gene (TRGγ) locus FEES Lett 1987, 224: 291-296
24. Greiner TC, Raffeid M, Lutz C, Dick F, Jaffe ES. Analysis of T cell receptor-γ gene rearrangements by denaturing gradient gel electrophoresis of GC-clamped polymerase chain reaction products. Am J Pathol 1995; 146: 46-55.
25. Schlegelberger B. Himmler A, Gödde E, Grote W, Feller AC, Lennert K. Cytogenetic findings in peripheral T-cell lymphomas as a basis for distinguishing low-grade and high-grade lymphomas. Blood 1994; 83: 501-511
26. Furley AJ, Mizutam S, Weilbaecher D, et al Developmentally regulated rearrangement and expression of genes encoding the T cell receptor-T3 complex. Cell 1986; 46: 75-78.
27. Campana DF, Thompson JS, Amlot P, Brown S, Janossy G. The cytoplasmic expression of CD3 antigen in normal and malignant cells of the T lymphoid lineage. J Immunol 1987; 138; 648-654.
28. Lipkowitz S, Stern MH, Kirsch IR. Hybrid T cell receptor genes formed by interlocus recombination in normal and ataxia-telangiectasia lymphocytes. J Exp Med 1990; 172: 409-418.
29. Gaulard P, Kanavaros P, Farcet JP, et al. Bone marrow immunohistochemical findings in peripheral T-cell lymphoma' a study of 38 cases. Hum Pathol 1991; 22: 331-338.
30. Tycko B, Palmer JD, Link MP, Smith SD, Sklar J. Polymerase cham reaction amplification of rearranged antigen receptor genes using junction-specific oligonueleotides. possible application for detection of minimal residual disease in acute lymphoblastic leukemia Cancer Cell 1990; 7: 47-55.
31. Armitage JO, Greer JP, Levine AM, et al. Peripheral T-cell lymphoma. Cancer 1989; 63: 158-163.
32. Lefranc MP, Forster A, Baer R, Stinson M, Rabbits T Diversity and rearrangement of the human T cell rearranging 7 genes: nine germ-line variable genes belonging to two subgroups. Cell 1986; 45: 237-246
33. Forster A, Huck S, Ghanem N, Lefranc MP, Rabbits TH. New subgroups in the human T cell rearranging Vγ gene locus. EMBO J 1987; 6: 1945-1950.
34. Huck S, Dariavach P, Lefranc MP. Variable region genes in the human T-cell rearranging gamma (TRG) locus; V-J junction and homoloey with the mouse genes. EMBO J 1988; 7: 719-726.
35. Lefranc MP, Rabbits TH. Two tandemly organized human genes encoding the T-cell γ constant-region sequences show multiple rearrangement in different T-cell types. Nature 1985; 316: 464-466.