SNP rs1801157 significantly correlates with distant metastasis in CXCL12 expressing esophagogastric cancer

International Journal of Oncology

Volumn 39, Issue 2, 2011, Pages 515-520

  Schimanski, Carl Christoph ^a   Jordan, Mareike ^a   Schlaegel, Friederike ^a   Schmidtmann, Irene ^a   Lang, Hauke ^a   Galle, Peter R ^a   Moehler, Markus ^a   Gockel, Ines ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

Esophagogastric cancer; Polymorphisms of chemokine CXCL12; Prognosis; Tumor dissemination

Indexed keywords

STROMAL CELL DERIVED FACTOR 1;

ADULT; AGED; ARTICLE; DISTANT METASTASIS; ESOPHAGUS CANCER; FEMALE; HUMAN; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM; STOMACH ADENOCARCINOMA;

ADULT; AGED; AGED, 80 AND OVER; CHEMOKINE CXCL12; ESOPHAGEAL NEOPLASMS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MIDDLE AGED; NEOPLASM METASTASIS; NEOPLASM STAGING; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS; STOMACH NEOPLASMS; SURVIVAL ANALYSIS;

EID: 79959988416     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2011.1044     Document Type: Article

References (31)

1. Yoshie O, Imai T and Nomiyama H: Novel lymphocyte-specific CC chemokines and their receptors. J Leukoc Biol 62: 634-644, 1997. (Pubitemid 27519774)
2. Gerard C and Rollins BJ: Chemokines and disease. Nat Immunol 2: 108-115, 2001. (Pubitemid 33707927)
3. Muller A, Homey B, Soto H, et al: Involvement of chemokine receptors in breast cancer metastasis. Nature 410: 50-56, 2001. (Pubitemid 32225831)
4. Mashino K, Sadanaga N, Yamaguchi H, et al: Expression of chemokine receptor CCR7 is associated with lymph node metastasis of gastric carcinoma. Cancer Res 62: 2937-2941, 2002. (Pubitemid 34525782)
5. Scotton CJ Wilson JL, Scott K, et al: Multiple actions of the chemokine CXCL12 on epithelial tumor cells in human ovarian cancer. Cancer Res 62: 5930-5938, 2002. (Pubitemid 35204756)
6. Oonakahara K, Matsuyama W, Higashimoto I, Kawabata M, Arimura K and Osame M: Stromal-derived factor-1alpha/CXCL12-CXCR 4 axis is involved in the dissemination of NSCLC cells into pleural space. Am J Respir Cell Mol Biol 30: 671-677, 2004. (Pubitemid 38591218)
7. Kucia M, Jankowski K, Reca R, Wysoczynski M, Bandura L, Allendorf DJ, Zhang J, Ratajczak J and Ratajczak MZ: CXCR4-SDF-1 signalling, locomotion, Chemotaxis and adhesion. J Mol Histol 35: 233-245, 2004.
8. Kucia M, Reca R, Miekus K, Wanzeck J, Wojakowski W, Janowska-Wieczorek A, Ratajczak J and Ratajczak MZ: Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axis. Stem Cells 23: 879-894, 2005. (Pubitemid 41170944)
9. Schimanski CC, Schwald S, Simiantonaki N, Jayasinghe C, Gönner U, Wilsberg V, Junginger T, Berger MR, Galle PR and Moehler M: Effect of chemokine receptors CXCR4 and CCR7 on metastatic behaviour of human colorectal cancer. Clin Cancer Res 11: 1743-1758, 2005.
10. Gockel I, Schimanski CC, Heinrich C, Wehler T, Frerichs K, Drescher D, von Langsdorff C, Domeyer M, Biesterfeld S, Galle PR, Junginger T and Moehler M: Expression of chemokine receptor CXCR4 in esophageal squamous cell cancer and adenocarcinoma. BMC Cancer 6: 290, 2006.
11. Wehler T, Wolfert F, Schimanski CC, Gockel I, Herr W, Biesterfeld S, Seifert JK, Adwan H, Berger MR Junginger T, Galle PR and Moehler M: Strong expression of chemokine receptor CXCR4 by pancreatic cancer correlates with advanced disease. Oncol Rep 16: 1159-1164, 2006.
12. Schimanski CC, Bahre R, Gockel I, Müller A, Frerichs K, Hörner V, Teufel A, Simiantonaki N, Biesterfeld S, Wehler T, Schuler M, Achenbach T, Junginger T, Galle PR and Moehler M: Dissemination of hepatocellular carcinoma is mediated via chemokine receptor CXCR4 Br J Cancer 95: 210-217, 2006.
13. Ishigami S, Natsugoe S, Okumura H, Matsumoto M, Nakajo A, Uenosono Y, Arigami T, Uchikado Y, Setoyama T, Arima H, Hokita S and Aikou T Clinical implication of CXCL12 expression in gastric cancer. Ann Surg Oncol 14: 3154-3158, 2007. (Pubitemid 47594282)
14. Hölscher AH, Drebber U, Mönig SP, Schulte C, Vallböhmer D and Bollschweiler E: Early gastric cancer: lymph node metastasis starts with deep mucosal infiltration. Ann Surg 250: 791-797, 2009.
15. Strieter RM: Chemokines: not just leukocyte chemoattractants in the promotion of cancer. Nat Immunol 2: 285-286, 2001.
16. Rempel SA, Dudas S, Ge S and Gutierrez JA: Identification and localization of the cytokine SDF1 and its receptor, CXC chemokine receptor 4, to regions of necrosis and angiogenesis in human glioblastoma. Clin Cancer Res 6: 102-111, 2000. (Pubitemid 30064982)
17. Murphy PM: Chemokines and the molecular basis of cancer metastasis. N Engl J Med 345: 833-835, 2001.
18. Jo DY, Rafii S, Hamada T and Moore MA: Chemotaxis of primitive hematopoietic cells in response to stromal cell-derived factor-I. J Clin Investig 105: 101-111, 2000. (Pubitemid 30036392)
19. Locati M, Deuschle U, Massardi ML, Martinez FO, Sironi M, Sozzani S, Bartfai T and Mantovani A: Analysis of the gene expression profile activated by the CC chemokine ligand 5/RANTES and by lipopolysaccharide in human monocytes. J Immunol 168: 3557-3562, 2002. (Pubitemid 34250425)
20. Yasumoto K, Koizumi K, Kawashima A, Saitoh Y, Arita Y, Shinohara K, Minami T, Nakayama T, Sakurai H, Takahashi Y, Yoshie O and Saiki I: Role of the CXCL12/CXCR4 axis in peritoneal carcinomatosis of gastric cancer. Cancer Res 66: 2181-2187, 2006.
21. Tsuboi K, Kodera Y, Nakanishi H, Ito S, Mochizuki Y, Nakayama G, Koike M, Fujiwara M, Yamamura Y and Nakao A: Expression of CXCL12 and CXCR4 in pT3-stage gastric cancer does not correlate with peritoneal metastasis. Oncol Rep 20: 1117-1123, 2008.
22. Thorban S, Roder JD, Nekarda H, Funk A, Pantel K and Siewert JR Disseminated epithelial tumor cells in bone marrow of patients with esophageal cancer: detection and prognostic significance. World J Surg 20: 567-572, 1996.
23. Thorban S, Rosenberg R, Busch R and Roder RJ: Epithelial cells in bone marrow of oesophageal cancer patients: a significant prognostic factor in multivariate analysis. Br J Cancer 83: 35-39, 2000. (Pubitemid 30352714)
24. Koshiba T, Hosotani R, Miyamoto Y, Ida J Tsuji S, Nakajima S, Kawaguchi M, Kobayashi H, Doi R, Hori T, Fujii N and Imamura M: Expression of stromal cell-derived factor 1 and CXCR4 ligand receptor system in pancreatic cancer: a possible role for tumor progression. Clin Cancer Res 6: 3530-3535, 2000.
25. Dimberg J, Hugander A, Löfgren S and Wågstäter D: Polymorphism and circulating levels of the chemokine CXC12 in colorectal cancer patients. Int J Mol Med 1: 11-15, 2007.
26. Hidalgo-Pascual M, Galan J, Chaves-Conde M, Ramírez-Armengol JA, Moreno C, Calvo E, Pelaez P, Crespo C, Ruiz A and Royo JL: Analysis of CXCL12 3′UTR G>A polymorphism in colorectal cancer. Oncol Rep 18: 1583-1587, 2007.
27. Chang SC, Lin PC, Yang SH, Wang HS, Li AFY and Lin JK: SDF-1alpha G801A polymorphism predicts lymph node metastasis in stage T3 colorectal cancer. Ann Surg Oncol 16: 2323-2330, 2009.
28. Razmkhah M, Talei AR, Doroudchi M, Khalili-Azad T and Ghaderi A: Stromal cell-derived factor-1 (SDF-1) alleles and susceptibility to breast carcinoma. Cancer Lett 225: 261-266, 2005. (Pubitemid 40835873)
29. Zafiropoulos A, Crikas N, Passam AM and Spandidos DA: Significant involvement of CCR2-641 and CXCL12-3a in the development of sporadic breast cancer. J Med Genet 41: e59, 2004.
30. Rubin JB, Kung AL, Klein RS, et al: A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors. Proc Natl Acad Sci USA 100: 13513-13518, 2003. (Pubitemid 37444773)
31. De Clercq E: Recent advances on the use of the CXCR4 antagonist plerixafor (AMD3100, Mozobil™) and potential of other CXCR4 antagonists as stem cell mobilizers. Pharmacol Ther 128: 509-518, 2010.