Structural and functional analysis of critical amino acids in TMVI of the NHE1 isoform of the Na+/H+ exchanger

Biochimica et Biophysica Acta - Biomembranes

Volumn 1808, Issue 9, 2011, Pages 2327-2335

  Tzeng, Jennifer ^a   Lee, Brian L ^a   Sykes, Brian D ^a   Fliegel, Larry ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Cation coordination; Membrane protein; Na+ H+ exchanger; NhaA; NMR; Site specific mutagenesis

Indexed keywords

ALANINE; AMINO ACID; ARGININE; ASPARAGINE; GLUTAMIC ACID; ISOLEUCINE; ISOPROTEIN; LEUCINE; MUTANT PROTEIN; PROTEIN TMVI; SODIUM PROTON EXCHANGE PROTEIN; SODIUM PROTON EXCHANGE PROTEIN 1; TRYPSIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL MEMBRANE CONDUCTANCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEFECT; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; PROTEIN TARGETING; RESIDUE ANALYSIS; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS;

AMINO ACIDS; ANIMALS; BASE SEQUENCE; CATION TRANSPORT PROTEINS; CELL DIFFERENTIATION; CRICETINAE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; HYDROGEN-ION CONCENTRATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN CONFORMATION; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; SODIUM-HYDROGEN ANTIPORTER; TIME FACTORS;

MAMMALIA;

EID: 79959955205     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2011.05.004     Document Type: Article

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