NADPH oxidase-dependent formation of reactive oxygen species contributes to angiotensin II-induced epithelial-mesenchymal transition in rat peritoneal mesothelial cells

International Journal of Molecular Medicine

Volumn 28, Issue 3, 2011, Pages 405-412

  Chang, Jie ^a   Jiang, Zongpei ^a   Zhang, Haiyan ^a   Zhu, Hengmei ^a   Zhou, Shu Feng ^b   Yu, Xueqing ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b RMIT UNIVERSITY   (Australia)

Author keywords

Angiotensin II; NADPH oxidase; Peritoneal mesothelial cells; Reactive oxygen species

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ANGIOTENSIN II; DICHLOROFLUORESCEIN; DIPHENYLIODONIUM SALT; LOSARTAN; MESSENGER RNA; OXIDOREDUCTASE; PLASMINOGEN ACTIVATOR INHIBITOR 1; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE SUBUNIT P47PHOX; UNCLASSIFIED DRUG; UVOMORULIN;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL CYCLE ARREST; CELL GROWTH; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CULTURE MEDIUM; DRUG INHIBITION; EPITHELIAL MESENCHYMAL TRANSITION; EXTRACELLULAR MATRIX; FLUOROMETRY; INTRACELLULAR MEMBRANE; MESOTHELIUM CELL; NONHUMAN; PERITONEAL MESOTHELIAL CELL; PERITONEUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; RAT; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SERUM; WESTERN BLOTTING;

ACTINS; ANGIOTENSIN II; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; BLOTTING, WESTERN; CADHERINS; CELL DEDIFFERENTIATION; CELLS, CULTURED; CULTURE MEDIA, SERUM-FREE; DOWN-REGULATION; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; EXTRACELLULAR MATRIX; LOSARTAN; MALE; MICROSCOPY, CONFOCAL; NADH, NADPH OXIDOREDUCTASES; ONIUM COMPOUNDS; PERITONEAL FIBROSIS; PLASMINOGEN ACTIVATOR INHIBITOR 1; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; UP-REGULATION;

EID: 79959940459     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2011.683     Document Type: Article

References (37)

1. Williams JD, Craig KJ, Topley N, et al: Morphologic changes in the peritoneal membrane of patients with renal disease. J Am Soc Nephrol 13: 470-479, 2002. (Pubitemid 34106290)
2. Ha H, Cha MK, Choi HN and Lee HB: Effects of peritoneal dialysis solutions on the secretion of growth factors and extra-cellular matrix proteins by human peritoneal mesothelial cells. Perit Dial Int 22: 171-177, 2002. (Pubitemid 34546327)
3. Gotloib L, Wajsbrot V, Cuperman Y and Shostak A: Acute oxidative stress induces peritoneal hyperpermeability, mesothelial loss, and fibrosis. J Lab Clin Med 143: 31-40, 2004. (Pubitemid 38156414)
4. Rampino T and Dal Canton A: Peritoneal dialysis and epithelial-to- mesenchymal transition. N Engl J Med 348: 2037-2039, 2003. (Pubitemid 36569998)
5. Lee HB, Yu MR, Song JS and Ha H: Reactive oxygen species amplify protein kinase C signaling in high glucose-induced fibronectin expression by human peritoneal mesothelial cells. Kidney Int 65: 1170-1179, 2004. (Pubitemid 38406955)
6. Aroeira LS, Aguilera A, Selgas R, et al: Mesenchymal conversion of mesothelial cells as a mechanism responsible for high solute transport rate in peritoneal dialysis: role of vascular endothelial growth factor. Am J Kidney Dis 46: 938-948, 2005. (Pubitemid 41505470)
7. Shen WL, Gao PJ, Che ZQ, et al: NAD(P)H oxidase-derived reactive oxygen species regulate angiotensin-II induced adventitial fibroblast phenotypic differentiation. Biochem Biophys Res Commun 339: 337-343, 2006.
8. Azhar M, Schultz Jel J, Grupp I, et al: Transforming growth factor beta in cardiovascular development and function. Cytokine Growth Factor Rev 14: 391-407, 2003. (Pubitemid 37099453)
9. Ruiz-Ortega M, Ruperez M, Esteban V, et al: Angiotensin II: a key factor in the inflammatory and fibrotic response in kidney diseases. Nephrol Dial Transplant 21: 16-20, 2006. (Pubitemid 43057101)
10. Bader M, Peters J, Baltatu O, Müller DN, Luft FC and Ganten D: Tissue renin-angiotensin systems: new insights from experimental animal models in hypertension research. J Mol Med 79: 76-102, 2001. (Pubitemid 32285333)
11. Noh H, Lee HB, Yu MR, Kim YO, Kim JH and Lee HB: Angiotensin II mediates high glucose-induced TGF-beta1 and fibronectin upregulation in HPMC through reactive oxygen species. Perit Dial Int 25: 38-47, 2005. (Pubitemid 40378496)
12. Sawada T, Ishii Y, Tojimbara T, Nakajima I, Fuchinoue S and Teraoka S: The ACE inhibitor, quinapril, ameliorates peritoneal fibrosis in an encapsulating peritoneal sclerosis model in mice. Pharmacol Res 46: 505-510, 2002. (Pubitemid 35435692)
13. Evans JL, Goldfine ID, Maddux BA and Grodsky GM: Oxidative stress and stress-activated signaling pathways: A unifying hypothesis of type 2 diabetes. Endocr Rev 23: 599-622, 2002. (Pubitemid 35191625)
14. Li JM and Shah AM: ROS Generation by nonphagocytic NADPH oxidase: potential relevance in diabetic nephropathy J Am Soc Nephrol 14 S221-S226, 2003.
15. Touyz RM: Reactive oxygen species and angiotensin II signaling in vascular cells - implications in cardiovascular disease. Braz J Med Biol Res 37: 1263-1273, 2004.
16. Kimura S, Zhang GX, Nishiyama A, et al: Role of NAD(P)H oxidase- and michotodria-derived reactive oxygen species in cardioprotection of ischemic reperfusion injury by angiotensin II. Hypertension 45: 860-866, 2005. (Pubitemid 40628929)
17. Li JM and Shah AM: Mechanism of endothelial cell NADPH oxidase activation by angiotensin II. J Biol Chem 278: 12094-12100, 2003.
18. Alvarez Y, Pérez-Girón JV, Hernanz R, et al: Losartan reduces the increased participation of cyclooxygenase-2-derived products in vascular responses of hypertensive rats. J Pharmacol Exp Ther 321: 381-388, 2007. (Pubitemid 46456962)
19. Bataller R, Schwabe RF, Choi YH, et al; NADPH oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosis. J Clin Invest 112: 1383-1394, 2003. (Pubitemid 38057692)
20. Akiba T, Ota T, Fushimi K, et al: Water channel AQP21 in the primary cell culture of rat peritoneum. Adv Perit Dial 15: 3-6, 1999.
21. Ha H, Yu MR, Choi YJ, Kitamura M and Lee HB: Role of high glucose-induced nuclear factor-κB activation in monocyte chemoattractant protein-1 expression by mesangial cells. J Am Soc Nephrol 13: 894-902, 2002. (Pubitemid 34274085)
22. Rhyu DY, Yang YQ, Ha H, et al: Role of reactive oxygen species in TGF-β-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells. J Am Soc Nephrol 16: 667-675, 2005. (Pubitemid 41725103)
23. Chen L, Liu BC, Zhang XL, Zhang JD, Liu H and Li MX: Influence of connective tissue growth factor antisense oligonucleotide on angiotensin Il-induced epithelial mesenchymal transition in HK2 cells. Acta Pharmacol Sin 27: 1029-1036, 2006. (Pubitemid 44127912)
24. Volpini RA, da Silva CG, Costa RS and Coimbra TM: Effect of enalapril and losartan on the events that precede diabetic nephropathy in rats. Diabetes Metab Res Rev 19: 43-51, 2003. (Pubitemid 36285373)
25. Park SY, Song CY, Kim BC, Hong HK and Lee HS: Angiotensin II mediates LDL-induced superoxide generation in mesangial cells. Am J Physiol Renal Physiol 285: F909-F915, 2003. (Pubitemid 37288637)
26. Ha H and Lee HB: Reactive oxygen species and matrix remodeling in diabetic nephropathy. J Am Soc Nephrol 14 (8 Suppl 3): S246-S249, 2003. (Pubitemid 36903934)
27. Jiang ZP, Seo J, Ha H, et al: ROS mediate TGF-β1-induced plasminogen activator inhibitor-1 upregulation in mesangial cells. Biochem Biophys Res Commun 309: 961-966, 2003. (Pubitemid 37122623)
28. Lee HB, Yu MR, Yang YQ, Jiang Z and Ha H: Reactive oxygen species-regulated signaling pathways in diabetic nephropathy. J Am Soc Nephrol 14 (8 Suppl 3): S241-S245, 2003. (Pubitemid 36903933)
29. Babior BM: NADPH oxidase: an update. Blood 93: 1464-1476, 1999.
30. Babior BM, Lambeth JD and Nauseef W: The neutrophil NADPH oxidase. Arch Biochem Biophys 397 342-344, 2002.
31. Nauseef WM: Assembly of the phagocyte NADPH oxidase. Histochem Cell Biol 122: 277-291, 2004.
32. Landmesser U, Cai H, Dikalov S, et al: Role of p47(phox) in vascular oxidative stress and hypertension caused by angiotensin II. Hypertension 40: 511-515, 2002.
33. Mizuki K, Takeya R, Kuribayashi F, et al: A region C-terminal to the proline-rich core of p47phox regulates activation of the phagocyte NADPH oxidase by interacting with the C-terminal SH3 domain of p67phox. Arch Biochem Biophys 444: 185-194, 2005 (Pubitemid 41728350)
34. Kiribayashi K, Masaki T, Naito T, et al: Angiotensin II induces fibronectin expression in human peritoneal cells via ERK1/2 and p38 MAPK Kidney Int 67: 1126-1135, 2005.
35. Lee YJ, Heo JS, Suh HN, Lee MY and Han HJ: Interleukin-6 stimulates alpha-MG uptake in renal proximal tubule cells: Involvement of STAT3, PI3K/Akt, MAPKs, and NF-kappaB. Am J Physiol Renal Physiol 293: F1036-F1046, 2007. (Pubitemid 47583935)
36. Tang EH, Leung FP, Huang Y, et al: Calcium and reactive oxygen species increase in endothelial cells in response to releasers of endothelium-derived contracting factor. Br J Pharmacol 151: 15-23, 2007. (Pubitemid 46676000)
37. Wan J and Winn LM: Benzene's metabolites alter c-MYB activity via reactive oxygen species in HD3 cells. Toxicol Appl Pharmacol 222: 180-189, 2007. (Pubitemid 47094867)