Timing the multiple cell death pathways initiated by Rose Bengal acetate photodynamic therapy

Cell Death and Disease

Volumn 2, Issue 6, 2011, Pages

  Panzarini, E ^a   Inguscio, V ^a   Dini, L ^a  

^a UNIVERSITY OF SALENTO   (Italy)

Author keywords

Apoptosis; Autophagy; Bcl 2 family; Caspases; ROS; Rose Bengal acetate

Indexed keywords

CASPASE 12; CASPASE 3; CASPASE 8; CASPASE 9; GLUCOSE REGULATED PROTEIN 78; HEAT SHOCK PROTEIN 70; PHOTOSENSITIZING AGENT; PROTEIN BCL 2; ROSE BENGAL; ROSE BENGAL ACETATE; UNCLASSIFIED DRUG; DRUG DERIVATIVE; REACTIVE OXYGEN METABOLITE;

ARTICLE; AUTOPHAGY; CELL DEATH; CELL ORGANELLE; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; HELA CELL; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; PHOTODYNAMIC THERAPY; PHOTOSENSITIZATION; PRIORITY JOURNAL; BIOLOGICAL MODEL; CELL CULTURE; DRUG EFFECT; ENDOPLASMIC RETICULUM; METABOLISM; OXIDATIVE STRESS; PHOTOCHEMOTHERAPY; STRUCTURE ACTIVITY RELATION; TIME;

CELL DEATH; CELLS, CULTURED; ENDOPLASMIC RETICULUM; HELA CELLS; HUMANS; MODELS, BIOLOGICAL; OXIDATIVE STRESS; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; REACTIVE OXYGEN SPECIES; ROSE BENGAL; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS;

EID: 79959932371     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2011.51     Document Type: Article

References (40)

1. Babilas P, Karrer S, Sidoroff A, Landthaler M, Szeimies RM. Photodynamic therapy in dermatology - an update. Photodermatol Photoimmunol Photomed 2005; 21: 142-149. (Pubitemid 40778615)
2. Calzavara-Pinton PG, Venturini M, Sala R. Photodynamic therapy: update 2006. Part 1: photochemistry and photobiology. J Eur Acad Dermatol Venereol 2007; 21: 293-302.
3. Oleinick NL, Morris RL, Belichenko I. The role of apoptosis in response to photodynamic therapy: what, where, why and how. Photochem Photobiol Sci 2002; 1: 1-21. (Pubitemid 37069701)
4. Hilf R. Mitochondria are targets of photodynamic therapy. J Bioenerg Biomembr 2007; 39: 85-89. (Pubitemid 46877177)
5. Kessel D, Luo Y, Mathieu P, Reiners JJ. Determinants of the apoptotic response to lysosomal photodamage. Photochem Photobiol 2000; 71: 196-200.
6. Piette J, Volanti C, Vantieghem A, Matroule JY, Habraken Y, Agostinis P. Cell death and growth arrest in response to photodynamic therapy with membrane-bound photosensitizers. Biochem Pharmacol 2003; 15: 1651-1659. (Pubitemid 38373358)
7. Buytaert E, Dewaele M, Agostinis P. Molecular effectors of multiple cell death pathways initiated by photodynamic therapy. Biochim Biophys Acta 2007; 1776: 86-107. (Pubitemid 47332075)
8. Plaetzer K, Kiesslich T, Oberdanner CB, Krammer B. Apoptosis following photodynamic tumor therapy: induction, mechanisms and detection. Curr Pharm Des 2005; 11: 1151-1165. (Pubitemid 40403374)
9. Bottiroli G, Croce AC, Balzarini P, Locatelli D, Baglioni P, Lo Nostro P et al. Enzyme-assisted cell photosensitization: a proposal for an efficient approach to tumor therapy and diagnosis. The Rose Bengal fluorogenic substrate. Photochem Photobiol 1997; 66: 374-383. (Pubitemid 127494528)
10. Croce AC, Supino R, Lanza KS, Locatelli D, Baglioni P, Bottiroli G. Photosensitizer accumulation in spontaneous multidrug resistant cells: a comparative study with rhodamine 123, Rose Bengal and photofrin. Photochem Photobiol Sci 2002; 1: 71-78. (Pubitemid 37069709)
11. Soldani C, Croce AC, Bottone MG, Fraschini A, Biggiogera M, Bottiroli G et al. Apoptosis in tumor cells photosensitized with Rose Bengal acetate is induced by multiple organelle photodamage. Histochem Cell Biol 2007; 128: 485-495. (Pubitemid 350163686)
12. Panzarini E, Tenuzzo B, Palazzo F, Chionna A, Dini L. Apoptosis induction and mitochondria alteration in human HeLa tumor cells by photoproducts of Rose Bengal acetate. J Photochem Photobiol B 2006; 83: 39-47. (Pubitemid 43372641)
13. Panzarini E, Tenuzzo B, Dini L. Photodynamic therapy-induced apoptosis of HeLa cells. Ann NY Acad Sci 2009; 1171: 617-626.
14. Soldani C, Bottone MG, Croce AC, Fraschini A, Bottiroli G, Pellicciari C. The Golgi apparatus is a primary site of intracellular damage after photosensitization with Rose Bengal acetate. Eur J Histochem 2004; 48: 443-448.
15. Dini L, Inguscio V, Tenuzzo B, Panzarini E. Rose Bengal acetate photodynamic therapyinduced autophagy. Cancer Biol Ther 2010; 10: 1048-1055.
16. Kessel D, Oleinick NL. Initiation of autophagy by photodynamic therapy. Methods Enzymol 2009; 453: 1-16.
17. Zitvogel L, Kepp O, Senovilla L, Menger L, Chaput N, Kroemer G. Immunogenic tumor cell death for optimal anticancer therapy: the calreticulin exposure pathway. Clin Cancer Res 2010; 16: 3100-3104.
18. Kepp P, Tesniere A, Shlemmer F, Michaud M, Senovilla L, Zitvogel L et al. Immunogenic cell death modalities and their impact on cancer treatment. Apoptosis 2009; 14: 364-375.
19. Schmitz I, Kirchhoff S, Krammer PH. Regulation of death receptor-mediated apoptosis pathways. Int J Biochem Cell Biol 2000; 32: 1123-1136. (Pubitemid 32008300)
20. Green DR, Kroemer G. The pathophysiology of mitochondrial cell death. Science 2004; 305: 626-629. (Pubitemid 39006738)
21. Shiraishi H, Okamoto H, Yoshimura A, Yoshida H. ER stress-induced apoptosis and caspase-12 activation occurs downstream of mitochondrial apoptosis involving Apaf-1. J Cell Sc 2006; 119: 3958-3966. (Pubitemid 44650869)
22. Burlacu A. Regulation of apoptosis by Bcl-2 family proteins. J Cell Mol Med 2003; 7: 249-257. (Pubitemid 37372044)
23. Dewaele M, Maes H. Agostinis P ROS-mediated mechanisms of autophagy stimulation and their relevance in cancer therapy. Autophagy 2010; 6: 838-854.
24. Finkel T, Holbrook NJ. Oxidants, oxidative stress and the biology of ageing. Nature 2000; 408: 239-247.
25. Carthy CM, Granville DJ, Jiang H, Levy JG, Rudin CM, Thompson CB et al. Early release of mitochondrial cytochrome c and expression of mitochondrial epitope 7A6 with a porphyrinderived photosensitizer: Bcl-2 and Bcl-xL overexpression do not prevent early mitochondrial events but still depress caspase activity. Lab Invest 1999; 79: 953-965. (Pubitemid 29400140)
26. Kim HR, Luo Y, Li G, Kessel D. Enhanced apoptotic response to photodynamic therapy after bcl-2 transfection. Cancer Res 1999; 59: 3429-3432. (Pubitemid 29334504)
27. Sun L, Chen T, Wang X, Chen Y, Wei X. Bufalin induces reactive oxygen species dependent Bax translocation and apoptosis in ASTC-a-1 Cells. Evid Based Complement Alternat Med 2009; e-pub ahead of print 10 June 2009.
28. Granville DJ, Shaw JR, Leong S, Carthy CM, Margaron P, Hunt DW et al. Release of cytochrome c, Bax migration, Bid cleavage, and activation of caspases 2, 3, 6, 7, 8, and 9 during endothelial cell apoptosis. Am J Pathol 1999; 155: 1021-1025. (Pubitemid 29488907)
29. Granville DJ, Cassidy BA, Ruehlmann DO, Choy JC, Brenner C, Kroemer G et al. Mitochondrial release of apoptosis-inducing factor and cytochrome c during smooth muscle cell apoptosis. Am J Pathol 2001; 159: 305-311. (Pubitemid 33704215)
30. Kessel D, Castelli M. Evidence that bcl-2 is the target of three photosensitizers that induce a rapid apoptotic response. Photochem Photobiol 2001; 74: 318-322.
31. Cirman T, Oresić K, Mazovec GD, Turk V, Reed JC, Myers RM et al. Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of Bid by multiple papain-like lysosomal cathepsins. J Biol Chem 2004; 279: 3578-3587. (Pubitemid 38140598)
32. Bottone MG, Soldani C, Fraschini A, Croce AC, Bottiroli G, Camboni T et al. Enzymeassisted photosensitization activates different apoptotic pathways in Rose Bengal acetate treated HeLa cells. Histochem Cell Biol 2009; 131: 391-399.
33. Verfaillie T, Salazar M, Velasco G, Agostinis P. Linking ER stress to autophagy: potential implications for cancer therapy. Int J Cell Biol 2010; e-pub ahead of print 17 January 2010.
34. Apel A, Herr I, Schwarz H, Rodemann HP, Mayer A. Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy. Cancer Res 2008; 68: 1485-1494. (Pubitemid 351346857)
35. Ogata M, Hino S, Saito A, Morikawa K, Kondo S, Kanemoto S et al. Autophagy is activated for cell survival after endoplasmic reticulum stress. Mol Cell Biol 2006; 26: 9220-9231. (Pubitemid 44904418)
36. Demaurex N, Distelhorst C. Cell biology. Apoptosis - the calcium connection. Science 2003; 300: 65-67. (Pubitemid 36423022)
37. Tsai YC, Weissman AM. The unfolded protein response, degradation from endoplasmic reticulum and cancer. Genes Cancer 2010; 1: 764-778.
38. Zhuang S, Kochevar IE. Ultraviolet A radiation induces rapid apoptosis of human leukemia cells by Fas ligand-independent activation of the Fas death pathways. Photochem Photobiol 2003; 78: 61-67.
39. Saleh A, Srinivasula SM, Balkir L, Robbins PD, Alnemri ES. Negative regulation of the Apaf-1 apoptosome by Hsp70. Nat Cell Biol 2000; 2: 476-483.
40. Coupienne I, Bontems S, Dewaele M, Rubio N, Habraken Y, Fulda S et al. NF-kappaB inhibition improves the sensitivity of human glioblastoma cells to 5-aminolevulinic acidbased photodynamic therapy. Biochem Pharmacol 2011; 81: 606-616.