Enzyme-assisted photosensitization activates different apoptotic pathways in Rose Bengal acetate treated HeLa cells

Histochemistry and Cell Biology

Volumn 131, Issue 3, 2009, Pages 391-399

  Bottone, Maria Grazia ^a   Soldani, Cristiana ^a   Fraschini, Annunzia ^a   Croce, Anna Cleta ^b   Bottiroli, Giovanni ^b   Camboni, Tania ^b   Scovassi, Anna Ivana ^b   Pellicciari, Carlo ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b CNR   (Italy)

Author keywords

Apoptosis; DNA electrophoresis; Fluorescence microscopy; Immunocytochemistry; Photosensitizers; Rose Bengal acetate

Indexed keywords

ACETIC ACID; APOPTOSIS INDUCING FACTOR; CASPASE 3; CASPASE 9; CELL NUCLEUS DNA; CYTOTOXIC AGENT; GENOMIC DNA; ROSE BENGAL;

APOPTOSIS; ARTICLE; CELL NUCLEUS; CELL ORGANELLE; CONTROLLED STUDY; DNA CLEAVAGE; DNA DEGRADATION; ELECTROPHORESIS; ENZYME ACTIVATION; FEMALE; FLUORESCENCE MICROSCOPY; HELA CELL; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; MITOCHONDRION; MOLECULAR WEIGHT; PHOTOSENSITIZATION; PRIORITY JOURNAL; UTERINE CERVIX CANCER;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CASPASE 9; CASPASES; DNA FRAGMENTATION; HELA CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; MICROSCOPY, FLUORESCENCE; PHOTOSENSITIZING AGENTS; ROSE BENGAL; SIGNAL TRANSDUCTION;

EID: 64949159695     PISSN: 09486143     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00418-008-0538-0     Document Type: Article

References (42)

1. P Agostinis A Vantieghem W Merlevede PAM Witte 2002 Hypericin in cancer treatment: more light on the way Int J Biochem Cell Biol 34 221 241
2. P Agostinis E Buytaert H Breyssens N Hendrickx 2004 Regulatory pathways in photodynamic therapy induced apoptosis Photochem Photobiol Sci 3 721 729
3. RD Almeida BJ Manadas AP Carvalho CB Duarte 2004 Intracellular signaling mechanisms in photodynamic therapy Biochim Biophys Acta 1704 59 86
4. K Berg J Moan 1997 Lysosomes and microtubules as targets for photochemotherapy of cancer Photochem Photobiol 65 403 409
5. G Bottiroli AC Croce P Balzarini D Locatelli P Baglioni P Lo Nostro M Monici R Pratesi 1997 Enzyme-assisted cell photodsensitization: a proposal for an efficient approach to tumor therapy and diagnosis. The Rose Bengal fluorogenic substrate Photochem Photobiol 66 74 383
6. Bottiroli G, Croce AC, Baglioni P, Monici M (2000) Fluorogenic substrates for diagnosis and photodynamic treatment of tumors. US Patent 6,036,941, 14 March 2000
7. Bottiroli G, Croce AC, Biggiogera M, Lanza KS, Fiorani S, Locatelli D (2001) Photosensitizer damage targets in Rose Bengal acetate treated cells. Laser Surg Med Suppl 13:41
8. MG Bottone C Soldani A Fraschini C Alpini AC Croce G Bottiroli C Pellicciari 2007 Enzyme-assisted photosensitization with rose Bengal acetate induces structural and functional alteration of mitochondria in HeLa cells Histochem Cell Biol 127 263 271
9. E Buytaert M Dewaele P Agostinis 2007 Molecular effectors of multiple cell death pathways initiated by photodynamic therapy Biochim Biophys Acta 1776 86 107
10. AC Croce E Wyroba G Bottiroli 1992 Distribution and retention of rose bengal and disulphonated aluminium phthalocyanine: a comparative study in unicellular eukaryote J Photochem Photobiol 16 319 330
11. AC Croce R Supino KS Lanza D Locatelli P Baglioni G Bottiroli 2002 Photosensitizer accumulation in spontaneous multidrug resistant cells: a comparative study with Rhodamine 123, Rose Bengal acetate and Photofrin Photochem Photobiol Sci 1 71 78
12. J Dhale HB Steen J Moan 1999 The mode of cell death induced by photodynamic treatment depends on cell density Photochem Photobiol 70 363 368
13. J Dhale S Bagdonas O Kaathus G Olsen HB Steen J Moan 2000 The bystander effect in photodynamic inactivation of cells Biochim Biophys Acta 1475 273 280
14. DE Dolmans D Fukumura RK Jain 2003 Photodynamic therapy for cancer Nat Rev Cancer 3 380 387
15. M Donzelli R Bernardi C Negri E Prosperi L Padovan C Lavialle O Brison AI Scovassi 1999 Apoptosis-prone phenotype of human colon carcinoma cells with a high level amplification of the c-myc gene Oncogene 18 439 448
16. TJ Dougherty 2002 An update on photodynamic therapy applications J Clin Laser Med Surg 20 3 7
17. IE Furre MT Moller S Shahzidi JM Nesland Q Peng 2006 Involvement of both caspase-dependent and-independent pathways in apoptotic induction by hexaminolevulinate-mediated photodynamic therapy in human lymphoma cells Apoptosis 11 2031 2042
18. DJ Granville BM Mcmanus DW Hunt 2001 Photodynamic therapy: shedding light on the biochemical pathways regulating porphyrin-mediated cell death Histol Histopathol 16 309 317
19. R Hilf 2007 Mitochondria are target of photodynamic therapy J Bioenerg Biomembr 39 5 89
20. D Kessel Y Luo 1999 Photodynamic therapy: a mitochondrial inducer of apoptosis Cell Death Differ 6 28 35
21. D Kessel Y Luo Y Deng 1997 The role of subcellular localization in initiation of apoptosis by photodynamic therapy Photochem Photobiol 65 422 426
22. D Kessel Y Luo P Mathieu JJ Reiners 2000 Determinants of the apoptotic response to lysosomal photodamage Photochem Photobiol 71 196 200
23. D Kessel M Conley MG Vicente JJ Reiners 2005 Studies on the subcellular localization of the porphycene CPO Photochem Photobiol 81 569 572
24. D Kessel MGH Vicente JJ Reiners Jr 2006 Initiation of apoptosis and autophagy by photodynamic therapy Lasers Surg Med 38 482 488
25. Y Luo D Kessel 1997 Initiation of apoptosis versus necrosis by photodynamic therapy with chloroaluminum phthalocyanine Photochem Photobiol 66 479 483
26. J Moan K Berg 1991 The photodegradation of porphyrins in cells can be used to estimate the lifetime of singlet oxygen Photochem Photobiol 53 549 553
27. J Morgan AR Oseroff 2001 Mitochondria-based photodynamic anti-cancer therapy Adv Drug Deliv Rev 49 71 86
28. DC Neckers OM Valdes-Aguilera 1993 Photochemistry of the xanthene dyes Adv Photochem 18 315 394
29. M Niedre MS Patterson BC Wilson 2002 Direct near-infrared luminescence detection of singlet oxygen generated by photodynamic therapy in cells in vitro and tissues in vivo Photochem Photobiol 75 382 391
30. NL Oleinick RL Morris I Belichenko 2002 The role of apoptosis in response to photodynamic therapy: what, where, why, and how Photochem Photobiol Sci 1 1 21
31. E Panzarini B Tenuzzo F Palazzo A Chionna L Dini 2006 Apoptosis induction and mitochondria alteration in human HeLa tumour cells by photoproducts of Rose Bengal acetate J Photochem Photobiol B Biol 83 39 47
32. J Piette C Volanti A Vantieghem JY Matroule Y Habraken P Agostinis 2003 Cell death and growth arrest in response to photodynamic therapy with membrane-bound photosensitizers Biochem Pharmacol 15 1651 1659
33. C Soldani AI Scovassi 2002 Poly(ADP-ribose) polymerase-1 cleavage during apoptosis: an update Apoptosis 7 321 328
34. C Soldani MG Bottone C Pellicciari AI Scovassi 2001 Two-color fluorescence detection of Poly (ADP-Ribose) Polymerase-1 (PARP-1) cleavage and DNA strand breaks in etoposide-induced apoptotic cells Eur J Histochem 45 389 392
35. C Soldani M Lazzè MG Bottone G Tognon M Biggiogera C Pellicciari AI Scovassi 2001 Poly(ADP-ribose) polymerase cleavage during apoptosis: when and where? Exp Cell Res 269 193 201
36. C Soldani MG Bottone AC Croce A Fraschini G Bottiroli C Pellicciari 2004 The Golgi apparatus is a primary site of intracellular damage after photosensitization with rose Bengal acetate Eur J Histochem 48 443 448
37. C Soldani MG Bottone AC Croce A Fraschini M Biggiogera G Bottiroli C Pellicciari 2007 Apoptosis in tumor cells photosensitized with rose Bengal acetate is induced by multiple organelle photodamage Histochem Cell Biol 128 485 495
38. MH Teiten L Bezdetnaya P Morliere R Santus F Guillemin 2003 Endoplasmic reticulum and Golgi apparatus are the preferential sites of Foscan localisation in cultured tumour cells Br J Cancer 88 146 152
39. I Vermes C Haanen H Steffens-Nakken C Reutelingsperger 1995 A novel assay for apoptosis Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V J Immunol Methods 184 39 51
40. MB Vrouenraets GW Visser GB Snow GA van Dongen 2003 Basic principles, applications in oncology and improved selectivity of photodynamic therapy Anticancer Res 23 505 522
41. L Wyld MW Reed NJ Brown 2001 Differential cell death response to photodynamic therapy is dependent on dose and cell type Br J Cancer 84 1384 1386
42. VJ Yuste I Sanchez-Lopez C Solé RS Moubarak JR Bayaskas X Dolcet M Encinas SA Susin JX Comella 2005 The contribution of Apoptosis-inducing factor, caspases-activated DNase, and inhibitor of caspase-activated DNase to the nuclear phenotype and DNA degradation during apoptosis J Biol Chem 280 35670 35683