The possibilities of practical application of transgenic mammalian species generated by somatic cell cloning in pharmacology, veterinary medicine and xenotransplantology

Polish Journal of Veterinary Sciences

Volumn 14, Issue 2, 2011, Pages 329-340

  Samiec, M ^a   Skrzyszowska, M ^a  

^a NATIONAL RESEARCH INSTITUTE OF ANIMAL PRODUCTION   (Poland)

Author keywords

Kidney; Male accessory sex gland; Somatic cell nuclear transfer; Transgenesis; Urinary bladder; Veterinary medicine; Xenotransplantology

Indexed keywords

ANIMAL; CLONING; GENETICS; MAMMAL; METHODOLOGY; PHARMACOLOGY; REVIEW; TRANSGENIC ANIMAL; VETERINARY MEDICINE; XENOGRAFT;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CLONING, ORGANISM; MAMMALS; PHARMACOLOGY; TRANSPLANTATION, HETEROLOGOUS; VETERINARY MEDICINE;

ANIMALIA; MAMMALIA; RODENTIA; SUIDAE; SUS;

EID: 79959906410     PISSN: 15051773     EISSN: None     Source Type: Journal    
DOI: 10.2478/v10181-011-0051-6     Document Type: Review

References (62)

1. Bates JM, Raffi HM, Prasadan K, Mascarenhas R, Laszik Z, Maeda N, Hultgren SJ, Kumar S (2004) Tamm-Horsfall protein knockout mice are more prone to urinary tract infection: rapid communication. Kidney Int 65: 791-797. (Pubitemid 38251055)
2. Bondioli K, Ramsoondar J, Williams B, Costa C, Fodor W (2001) Cloned pigs generated from cultured skin fibroblasts derived from a H-transferase transgenic boar. Mol Reprod Dev 60: 189-195. (Pubitemid 32847128)
3. Chen SH, Vaught TD, Monahan JA, Boone J, Emslie E, Jobst PM, Lamborn AE, Schnieke A, Robertson L, Colman A, Dai Y, Polejaeva IA, Ayares DL (2002) Efficient production of transgenic cloned calves using preimplantation screening. Biol Reprod 67: 1488-1492. (Pubitemid 35204926)
4. +/+ mice. Neuroreport 19: 1027-1031.
5. Criado JR, Sánchez-Alavez M, Conti B, Giacchino JL, Wills DN, Henriksen SJ, Race R, Manson JC, Chesebro B, Oldstone MB (2005) Mice devoid of prion protein have cognitive deficits that are rescued by reconstitution of PrP in neurons. Neurobiol Dis 19: 255-265. (Pubitemid 40544743)
6. Sc formation by lentiviral gene transfer of PrP containing dominant negative mutations. J Cell Sci 117: 5591-5597.
7. Dai Y, Vaught TD, Boone J, Chen SH, Phelps CJ, Ball S, Monahan JA, Jobst PM, McCreath KJ, Lamborn AE, Cowell-Lucero JL, Wells KD, Colman A, Polejaeva IA, Ayares DL (2002) Targeted disruption of the α1,3-galactosyltransferase gene in cloned pigs. Nat Biotechnol 20: 251-255. (Pubitemid 34205417)
8. Denning C, Dickinson P, Burl S, Wylie D, Fletcher J, Clark AJ (2001a) Gene targeting in primary fetal fibroblasts from sheep and pig. Cloning Stem Cells 3: 221-231. (Pubitemid 34123564)
9. Denning C, Burl S, Ainslie A, Bracken J, Dinnyes A, Fletcher J, King T, Ritchie M, Ritchie WA, Rollo M, de Sousa P, Travers A, Wilmut I, Clark AJ (2001b) Deletion of the α(1,3)galactosyl transferase (GGTA1) gene and the prion protein (PrP) gene in sheep. Nat Biotechnol 19: 559-562. (Pubitemid 32521188)
10. Dyck MK, Gagné D, Ouellet M, Sénéchal JF, Bélanger E, Lacroix D, Sirard MA, Pothier F. (1999) Seminal vesicle production and secretion of growth hormone into seminal fluid. Nat Biotechnol 17: 1087-1090. (Pubitemid 29533547)
11. Echelard Y, Ziomek CA, Meade HM (2006) Production of recombinant therapeutic proteins in the milk of transgenic animals. BioPharm International 19: 36-46. (Pubitemid 44232256)
12. Galili U (2001) The a-gal epitope (Galα1-3Galß1-4GlcNAc-R) in xenotransplantation. Biochimie 83: 557-563.
13. Golding MC, Long CR, Carmell MA, Hannon GJ, Westhusin ME (2006) Suppression of prion protein in livestock by RNA interference. Proc Natl Acad Sci USA 103: 5285-5290.
14. Huang YJ, Chretien N, Bilodeau AS, Zhou JF, Lazaris A, Karatzas CN (2005) Goat uromodulin promoter directs kidney-specific expression of GFP gene in transgenic mice. BMC Biotechnol 5, published online, doi: 10.1186/1472-6750-5-9: 9-21.
15. Hyun S, Lee G, Kim D, Kim H, Lee S, Nam D, Jeong Y, Kim S, Yeom S, Kang S, Han J, Lee B, Hwang W (2003) Production of nuclear transfer-derived piglets using porcine fetal fibroblasts transfected with the enhanced green fluorescent protein. Biol Reprod 69: 1060-1068. (Pubitemid 37064636)
16. Joziasse DH, Oriol R (1999) Xenotransplantation: the importance of the Galα1,3Gal epitope in hyperacute vascular rejection. Biochim Biophys Acta 1455: 403-418. (Pubitemid 29436004)
17. Kang YK, Koo DB, Park JS, Choi YH, Kim HN, Chang WK, Lee KK, Han YM (2001) Typical demethylation events in cloned pig embryos. Clues on species-specific differences in epigenetic reprogramming of a cloned donor genome. J Biol Chem 276: 39980-39984.
18. Keefer CL, Baldassarre H, Keyston R, Wang B, Bhatia B, Bilodeau AS, Zhou JF, Leduc M, Downey BR, Lazaris A, Karatzas CN (2001) Generation of dwarf goat (Capra hircus) clones following nuclear transfer with transfected and nontransfected fetal fibroblasts and in vitro-matured oocytes. Biol Reprod 64: 849-856. (Pubitemid 32174056)
19. Kerr DE, Liang F, Bondioli KR, Zhao H, Kreibich G, Wall RJ, Sun TT (1998) The bladder as a bioreactor: urothelium production and secretion of growth hormone into urine. Nat Biotechnol 16: 75-79. (Pubitemid 28035953)
20. Kind A, Schnieke A (2008) Animal pharming, two decades on. Transgenic Res 17: 1025-1033.
21. Kolber-Simonds D, Lai L, Watt SR, Denaro M, Arn S, Augenstein ML, Betthauser J, Carter DB, Greenstein JL, Hao Y, Im GS, Liu Z, Meli GD, Murphy CN, Park KW, Rieke A, Ryan DJ, Sachs DH, Forsberg EJ, Prather RS, Hawley RJ (2004) Production of α-1,3-galactosyltransferase null pigs by means of nuclear transfer with fibroblasts bearing loss of heterozygosity mutations. Proc Natl Acad Sci USA 101: 7335-7340. (Pubitemid 38638033)
22. Kwon DN, Choi YJ, Park JY, Cho SK, Kim MO, Lee HT, Kim JH (2006) Cloning and molecular dissection of the 8.8 kb pig uroplakin II promoter using transgenic mice and RT4 cells. J Cell Biochem 99: 462-477. (Pubitemid 44435563)
23. Lai L, Kolber-Simonds D, Park KW, Cheong HT, Greenstein JL, Im GS, Samuel M, Bonk A, Rieke A, Day BN, Murphy CN, Carter DB, Hawley RJ, Prather RS (2002) Production of α-1,3-galactosyltransferase knockout pigs by nuclear transfer cloning. Science 295: 1089-1092. (Pubitemid 34132242)
24. Lee GS, Kim HS, Hyun SH, Lee SH, Jeon HY, Nam DH, Jeong YW, Kim S, Kim JH, Han JY, Ahn C, Kang SK, Lee BC, Hwang WS (2005) Production of transgenic cloned piglets from genetically transformed fetal fibroblasts selected by green fluorescent protein. Theriogenology 63: 973-991. (Pubitemid 40234505)
25. Lee JW, Wu SC, Tian XC, Barber M, Hoagland T, Riesen J, Lee KH, Tu CF, Cheng WT, Yang X (2003) Production of cloned pigs by whole-cell intracytoplasmic microinjection. Biol Reprod 69: 995-1001. (Pubitemid 37064629)
26. Lin JH, Zhao H, Sun TT (1995) A tissue-specific promoter that can drive a foreign gene to express in the suprabasal urothelial cells of transgenic mice. Proc Natl Acad Sci USA 92: 679-683.
27. Lobão-Soares B, Walz R, Carlotti CG Jr, Sakamoto AC, Calvo F, Terzian AL, da Silva JA, Wichert-Ana L, Coimbra NC, Bianchin MM (2007) Cellular prion protein regulates the motor behaviour performance and anxiety-induced responses in genetically modified mice. Behav Brain Res 183: 87-94.
28. Mann MR, Chung YG, Nolen LD, Verona RI, Latham KE, Bartolomei MS (2003) Disruption of imprinted gene methylation and expression in cloned preimplantation stage mouse embryos. Biol Reprod 69: 902-914. (Pubitemid 37064619)
29. McCreath KJ, Howcroft J, Campbell KH, Colman A, Schnieke AE, Kind AJ (2000) Production of gene-tar-geted sheep by nuclear transfer from cultured somatic cells. Nature 405: 1066-1069. (Pubitemid 30447792)
30. Meade H, Ziomek C (1998) Urine as a substitute for milk? Nat Biotechnol 16: 21-22. (Pubitemid 128723936)
31. Melo EO, Canavessi AM, Franco MM, Rumpf R (2007) Animal transgenesis: state of the art and applications. J Appl Genet 48: 47-61.
32. Mills JS, Needham M, Parker MG (1987) A secretory protease inhibitor requires androgens for its expression in male sex accessory tissues but is expressed constitutively in pancreas. EMBO J 6: 3711-3717.
33. Niemann H, Kues WA (2007) Transgenic farm animals: an update. Reprod Fertil Dev 19: 762-770. (Pubitemid 47206973)
34. Paleyanda RK, Velander WH, Lee TK, Scandella DH, Gwazdauskas FC, Knight JW, Hoyer LW, Drohan WN, Lubon H (1997) Transgenic pigs produce functional human factor VIII in milk. Nat Biotechnol 15: 971-975. (Pubitemid 27425935)
35. Phelps CJ, Koike C, Vaught TD, Boone J, Wells KD, Chen SH, Ball S, Specht SM, Polejaeva IA, Monahan JA, Jobst PM, Sharma SB, Lamborn AE, Garst AS, Moore M, Demetris AJ, Rudert WA, Bottino R, Bertera S, Trueco M, Starzl TE, Dai Y, Ayares DL (2003) Production of α1,3-galactosyltransferase-deficient pigs. Science 299: 411-414.
36. 2+-buffering in prion-null mice: association with reduced afterhyperpolarizations in CA1 hippocampal neurons. J Neurosci 28: 3877-3886.
37. Ramsoondar JJ, Machaty Z, Costa C, Williams BL, Fodor WL, Bondioli KR (2003) Production of α1,3-galactosyl-transferase-knockout cloned pigs expressing human α1,2-fucosylosyltransferase. Biol Reprod 69: 437-445. (Pubitemid 36885946)
38. Ryoo ZY, Kim MO, Kim KE, Bahk YY, Lee JW, Park SH, Kim JH, Byun SJ, Hwang HY, Youn J, Kim TY (2001) Expression of recombinant human granulocyte macrophage-colony stimulating factor (hGM-CSF) in mouse urine. Transgenic Res 10: 193-200. (Pubitemid 32532822)
39. Samiec M, Skrzyszowska M, Smorqg Z (2003) Effect of activation treatments on the in vitro developmental potential of porcine nuclear transfer embryos. Czech J Anim Sci 48: 499-507. (Pubitemid 41138294)
40. Samiec M (2004) Development of pig cloning studies: past, present and future. J Anim Feed Sci 13: 211-238.
41. Samiec M (2005) The effect of mitochondrial genome on architectural remodeling and epigenetic reprogramming of donor cell nuclei in mammalian nuclear transfer-derived embryos. J Anim Feed Sci 14: 393-422.
42. Santos F, Dean W (2004) Epigenetic reprogramming during early development in mammals. Reproduction 127: 643-651.
43. Schnieke AE, Kind AJ, Ritchie WA, Mycock K, Scott AR, Ritchie M, Wilmut I, Colman A, Campbell KH (1997) Human factor IX transgenic sheep produced by transfer of nuclei from transfected fetal fibroblasts. Science 278: 2130-2133. (Pubitemid 28028324)
44. Sharma A, Martin MJ, Okabe JF, Truglio RA, Dhanjal NK, Logan JS, Kumar R (1994) An isologous porcine promoter permits high level expression of human hemoglobin in transgenic swine. Biotechnology (NY) 12: 55-59.
45. Sharma A, Naziruddin B, Cui C, Martin MJ, Xu H, Wan H, Lei Y, Harrison C, Yin J, Okabe J, Mathews C, Stark A, Adams CS, Houtz J, Wiseman BS, Byrne GW, Logan JS (2003) Pig cells that lack the gene for α-1,3-galactosyl- transferase express low levels of the gal antigen. Transplantation 75: 430-436. (Pubitemid 36241133)
46. Shi W, Dirim F, Wolf E, Zakhartchenko V, Haaf T (2004) Methylation reprogramming and chromosomal aneuploidy in in vivo fertilized and cloned rabbit preimplantation embryos. Biol Reprod 71: 340-347. (Pubitemid 38915341)
47. Skrzyszowska M, Smora̧g Z, Slomski R, Ka̧tska- Ksia̧żkiewicz L, Kalak R, Michalak E, Wielgus K, Lehmann J, Lipiński D, Szalata M, Pławski A, Samiec M, Jura J, Gajda B, Ryñska B, Pieńkowski M (2006) Generation of transgenic rabbits by the novel technique of chimeric somatic cell cloning. Biol Reprod 74: 1114-1120. (Pubitemid 47394289)
48. Skrzyszowska M, Samiec M, Slomski R, Lipiński D, Mały E (2008) Development of porcine transgenic nuclear-transferred embryos derived from fibroblast cells transfected by the novel technique of nucleofection or standard lipofection. Theriogenology 70: 248-259.
49. Swanson ME, Martin MJ, O'Donnell KO, Hoover K, Lago W, Huntress V, Parsons CT, Pinkert CA, Pilder S, Logan JS (1992) Production of functional human hemoglobin in transgenic swine. Biotechnology (NY) 10: 557-559.
50. Thomson AJ, Marques MM, McWhir J (2003) Gene targeting in livestock. Reprod Suppl 61: 495-508.
51. Wang B, Zhou J (2003) Specific genetic modifications of domestic animals by gene targeting and animal cloning. Reprod Biol Endocrinol 1, published online, doi: 10.1186/1477-7827-1-103:103-110.
52. Weissmann C, Flechsig E (2003) PrP knock-out and PrP transgenic mice in prion research. Br Med Bull 66: 43-60. (Pubitemid 37173491)
53. Wrathall AE (2000) Risks of transmission of spongiform encephalopathies by reproductive technologies in domesticated ruminants. Livest Prod Sci 62: 287-316.
54. Yu G, Chen J, Yu H, Liu S, Chen J, Xu X, Sha H, Zhang X, Wu G, Xu S, Cheng G (2006) Functional disruption of the prion protein gene in cloned goats. J Gen Virol 87: 1019-1027.
55. Zbikowska HM, Soukhareva N, Behnam R, Chang R, Drews R, Lubon H, Hammond D, Soukharev S (2002a) The use of the uromodulin promoter to target production of recombinant proteins into urine of transgenic animals. Transgenic Res 11: 425-435. (Pubitemid 35301751)
56. Zbikowska HM, Soukhareva N, Behnam R, Lubon H, Hammond D, Soukharev S (2002b) Uromodulin promoter directs high-level expression of biologically active human α1-antitrypsin into mouse urine. Biochem J 365: 7-11. (Pubitemid 34756134)
57. Zhang J, Ramesh N, Chen Y, Li Y, Dilley J, Working P, Yu DC (2002) Identification of human uroplakin II promoter and its use in the construction of CG8840, a urothelium-specific adenovirus variant that eliminates established bladder tumors in combination with docetaxel. Cancer Res 62: 3743-3750. (Pubitemid 34728856)
58. -/- goats by gene targeting in adult fibroblasts. Transgenic Res 18: 163-171.
59. Zhu H, Zhang ZA, Xu C, Huang G, Zeng X, Wei S, Zhang Z, Guo Y (2003a) Targeting gene expression of the mouse uroplakin II promoter to human bladder cells. Urol Res 31: 17-21. (Pubitemid 36604897)
60. Zhu HJ, Zhang ZQ, Zeng XF, Wei SS, Zhang ZW, Guo YL (2004) Cloning and analysis of human UroplakinII promoter and its application for gene therapy in bladder cancer. Cancer Gene Ther 11: 263-272.
61. Zhu X, Cheng J, Gao J, Lepor H, Zhang ZT, Pak J, Wu XR (2002) Isolation of mouse THP gene promoter and demonstration of its kidney-specific activity in transgenic mice. Am J Physiol Renal Physiol 282: F608-F617. (Pubitemid 34654507)
62. Zhu X, Cheng J, Huang L, Gao J, Zhang ZT, Pak J, Wu XR (2003b) Renal tubule-specific expression and urinary secretion of human growth hormone: a kidney-based transgenic bioreactor. Transgenic Res 12: 155-162. (Pubitemid 36573228)