Cloning and characterization of an environmental DNA-derived gene cluster that encodes the biosynthesis of the antitumor substance BE-54017

Journal of the American Chemical Society

Volumn 133, Issue 26, 2011, Pages 9996-9999

  Chang, Fang Yuan ^a   Brady, Sean F ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-TUMORS; BACTERIAL SPECIES; BIOSYNTHETIC GENE CLUSTER; GENE CLUSTERS; HETEROLOGOUS EXPRESSION; INDOLOCARBAZOLES; MONOOXYGENASES; SECONDARY METABOLITES; SOIL DNA; TRANSPOSON MUTAGENESIS;

BIOCHEMISTRY; BIOSYNTHESIS; CLONING; DNA; ENCODING (SYMBOLS); GENE ENCODING; METABOLITES; MUTAGENESIS; SOILS;

GENE EXPRESSION;

ANTINEOPLASTIC AGENT; BE 54017; DNA; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DIMERIZATION; DNA LIBRARY; DRUG SYNTHESIS; ELECTROSPRAY MASS SPECTROMETRY; GENE CLUSTER; MOLECULAR CLONING; MUTAGENESIS; PROTON NUCLEAR MAGNETIC RESONANCE; TRANSPOSON; ULTRAVIOLET RADIATION;

ANTINEOPLASTIC AGENTS; CLONING, MOLECULAR; DNA; DNA, BACTERIAL; ENVIRONMENT; MULTIGENE FAMILY; SOIL MICROBIOLOGY; STREPTOMYCES;

EID: 79959894320     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja2022653     Document Type: Article

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