Determination of octreotide and assessment of matrix effects in human plasma using ultra high performance liquid chromatography-tandem mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 879, Issue 22, 2011, Pages 2081-2088

  Ismaiel, Omnia A ^a   Zhang, Tianyi ^b   Jenkins, Rand ^b   Karnes, H Thomas ^c  

^a Zagazig University   (Egypt)

^b Pharmaceutical Product Development   (United States)

^c VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Cancer; Ion suppression; Micro elution; Oncology; Peptide; Phospholipids; UPLC

Indexed keywords

ANALYTES; BACK-FLUSHING; BASELINE SEPARATION; CANCER; CHROMATOGRAPHIC CONDITIONS; CLINICAL PHARMACOKINETICS; COLUMN SWITCHING; CONCENTRATION RANGES; DIRECT MONITORING; HUMAN PLASMAS; INTERNAL STANDARDS; INTRA-ASSAY PRECISION; ION SUPPRESSION; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; MATRIX; MATRIX EFFECTS; METHOD DEVELOPMENT; MICRO ELUTION; OCTREOTIDE; PEAK SHAPES; PHOSPHOLIPID MATRIX; RUNTIMES; SELECTIVE EXTRACTION; THERAPEUTIC PEPTIDES; ULTRA HIGH PERFORMANCE; UPLC;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ION EXCHANGE; MASS SPECTROMETRY; PEPTIDES; PHOSPHOLIPIDS; PLASMA (HUMAN); PLASMAS; SIZE SEPARATION;

CHROMATOGRAPHY;

DRUG RESIDUE; OCTREOTIDE; PHOSPHOLIPID;

ACCURACY; ARTICLE; CALIBRATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG ISOLATION; DRUG MONITORING; DRUG STABILITY; HUMAN; HUMAN TISSUE; ION EXCHANGE; PARTICLE SIZE; PRIORITY JOURNAL; REPRODUCIBILITY; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; VALIDATION STUDY;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; HUMANS; LEAST-SQUARES ANALYSIS; OCTREOTIDE; PHOSPHOLIPIDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

EID: 79959880412     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2011.05.039     Document Type: Article

References (18)

1. Van den Broek I., Sparidans R.W., Schellens J.H.M., Beijnen J.H. J. Chromatogr. B 2008, 872:1.
2. Tucholska M., Florentinus A., Williams D., Marshall J.G. J. Proteomics 2010, 73:1254-1269.
3. Liu H., Finch J.W., Luongo J.A., Li G., Gebler J.C. J. Chromatogr. A 2006, 1135:43.
4. Liu A., Tweed J., Wujcik C.E. J. Chromatogr. B 2009, 877:1873.
5. Delahunty C., Yates J.R. Methods 2005, 35:248.
6. Jiang Y., Wang J., Wang Y., Du X., Zhang Y., Fawcett J.P., Gu J. Rapid Commun. Mass Spectrom. 2007, 21:3982.
7. Robben J.H., van den Brom W.E., Mol J.A., van Haeften T.W., Rijnberk A. Res. Vet. Sci. 2006, 80:25.
8. Woltering E.A., Mamikunian P.M., Zietz S., Krutzik S.R., Go V.L.W., Vinik A.I., Vinik E., O'Dorisio T.M., Mamikunian G. Pancreas 2005, 31:392.
9. Comets E., Mentre F., Nimmerfall F., Kawai R., Mueller I., Marbach P., Vonderscher J. J. Control. Release 1999, 59:197.
10. Novakov L., Matysov L., Solich P. Talanta 2006, 68:908.
11. Ismaiel O.A., Halquist M.S., Elmamly M.Y., Shalaby A., Karnes H.T. J. Chromatogr. B 2007, 859:84.
12. Ismaiel O.A., Halquist M.S., Elmamly M.Y., Shalaby A., Karnes H.T. J. Chromatogr. B 2008, 875:333.
13. Pascoe R., Foley J.P., Gusev A.I. Anal. Chem. 2001, 73:6014.
14. Jemal M. Biomed. Chromatogr. 2000, 14:422.
15. Chambers E., Wagrowski-Diehl D.M., Lu Z., Mazzeo J.R. J. Chromatogr. B 2007, 852:22.
16. Issaq H.J., Chan K.C., Janini G.M., Conrads T.P., Veenstra T.D. J. Chromatogr. B 2005, 817:35.
17. Little J.L., Wempe M.F., Buchanan C.M. J. Chromatogr. B 2006, 833:219.
18. US Department of Health and Human Services, Food and Drug Administration, 2001. http://www.fda.gov/cder/guidance/4252fnl.htm.