Effect of thymoquinone on hepatorenal dysfunction and alteration of CYP3A1 and spermidine/spermine N-1-acetyl-transferase gene expression induced by renal ischaemia-reperfusion in rats

Journal of Pharmacy and Pharmacology

Volumn 63, Issue 8, 2011, Pages 1037-1042

  Awad, Azza S ^a   Kamel, Rehab ^b   Sherief, Mohie Aldien Elsayed ^c  

^a Al Azhar University   (Egypt)

^b Ein Helwan   (Egypt)

^c BENHA UNIVERSITY   (Egypt)

Author keywords

CYP3A1; Oxidative stress; Renal ischaemia reperfusion; Spermidine spermine N 1 acetyl transferase; Thymoquinone

Indexed keywords

ACYLTRANSFERASE; ALANINE AMINOTRANSFERASE; CREATININE; CYTOCHROME P450 3A1; GLUTATHIONE TRANSFERASE; MALONALDEHYDE; MESSENGER RNA; POLYAMINE; SPERMIDINE SPERMINE N 1 ACETYL TRANSFERASE; SUPEROXIDE DISMUTASE; THYMOQUINONE; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CYP3A1 GENE; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; GENE; GENE EXPRESSION; GENE EXPRESSION REGULATION; HEPATORENAL SYNDROME; KIDNEY FUNCTION; KIDNEY ISCHEMIA; LIVER FUNCTION; MALE; NONHUMAN; POLYAMINE METABOLISM; RAT; REPERFUSION INJURY; SPERMIDINE SPERMINE N 1 ACETYL TRANSFERASE GENE;

ACETYLTRANSFERASES; ALANINE TRANSAMINASE; ANIMALS; ANTIOXIDANTS; BENZOQUINONES; CREATININE; CYTOCHROME P-450 CYP3A; DISEASE MODELS, ANIMAL; GENE EXPRESSION; GLUTATHIONE TRANSFERASE; ISCHEMIA; KIDNEY; KIDNEY DISEASES; LIVER; MALE; MALONDIALDEHYDE; NIGELLA SATIVA; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; RNA, MESSENGER; SEEDS; SPERMIDINE; SUPEROXIDE DISMUTASE;

EID: 79959871412     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/j.2042-7158.2011.01303.x     Document Type: Article

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