Cayman ataxia-related protein is a presynapse-specific caspase-3 substrate

Neurochemical Research

Volumn 36, Issue 7, 2011, Pages 1304-1313

  Itoh, Masanori ^a   Li, Shimo ^a   Ohta, Kazunori ^a   Yamada, Aiko ^a   Hayakawa Yano, Yoshika ^a   Ueda, Masashi ^a   Hida, Yoko ^a   Suzuki, Yoshihiro ^a   Ohta, Eri ^a   Mizuno, Akihito ^a   Banno, Yoshiko ^a   Nakagawa, Toshiyuki ^a  

^a GIFU UNIVERSITY   (Japan)

Author keywords

Apoptosis; Caspase; Cayman ataxia; Caytaxin; Synapse

Indexed keywords

BRAIN PROTEIN; CASPASE 3; CASPASE 7; CAYTAXIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN REGION; CARBOXY TERMINAL SEQUENCE; CAYMAN ATAXIA; CELL GRANULE; CEREBELLAR ATAXIA; CONTROLLED STUDY; DNA LIBRARY; DNA SEQUENCE; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME SPECIFICITY; HUMAN; HUMAN TISSUE; IN VITRO STUDY; MOUSE; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; CASPASE 3; CASPASE 7; CELL LINE; HUMANS; MAP KINASE KINASE 2; MICE; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; SYNAPSES;

EID: 79959869295     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-011-0430-5     Document Type: Article

References (42)

1. Kuranaga E, Kanuka H, Tonoki A, Takemoto K, Tomioka T et al (2006) Drosophila IKK-related kinase regulates nonapoptotic function of caspases via degradation of IAPs. Cell 126:583-596 (Pubitemid 44163604)
2. D'Amelio M, Cavallucci V, Cecconi F (2010) Neuronal caspase-3 signaling: not only cell death. Cell Death Differ 17:1104-1114
3. Yi CH, Yuan J (2009) The Jekyll and Hyde functions of caspases. Dev Cell 16:21-34
4. Kudryashova IV, Onufriev MV, Kudryashov IE, Gulyaeva NV (2009) Caspase-3 activity in hippocampal slices reflects changes in synaptic plasticity. Neurosci Behav Physiol 39:13-20
5. Bravarenko NI, Onufriev MV, Stepanichev MY, Ierusalimsky VN, Balaban PM et al (2006) Caspase-like activity is essential for long-term synaptic plasticity in the terrestrial snail Helix. Eur J Neurosci 23:129-140
6. Huesmann GR, Clayton DF (2006) Dynamic role of postsynaptic caspase-3 and BIRC4 in zebra finch song-response habituation. Neuron 52:1061-1072 (Pubitemid 44909403)
7. Fernando P, Brunette S, Megeney LA (2005) Neural stem cell differentiation is dependent upon endogenous caspase 3 activity. Faseb J 19:1671-1673 (Pubitemid 41429525)
8. Williams DW, Kondo S, Krzyzanowska A, Hiromi Y, Truman JW (2006) Local caspase activity directs engulfment of dendrites during pruning. Nat Neurosci 9:1234-1236 (Pubitemid 44454262)
9. Nikolaev A, McLaughlin T, O'Leary DD, Tessier-Lavigne M (2009) APP binds DR6 to trigger axon pruning and neuron death via distinct caspases. Nature 457:981-989
10. Arama E, Bader M, Rieckhof GE, Steller H (2007) A ubiquitin ligase complex regulates caspase activation during sperm differentiation in Drosophila. PLoS Biol 5:e251
11. Geisbrecht ER, Montell DJ (2004) A role for Drosophila IAP1-mediated caspase inhibition in Rac-dependent cell migration. Cell 118:111-125 (Pubitemid 38902818)
12. Li J, Brieher WM, Scimone ML, Kang SJ, Zhu H et al (2007) Caspase-11 regulates cell migration by promoting Aip1-Cofilin-mediated actin depolymerization. Nat Cell Biol 9:276-286
13. Louneva N, Cohen JW, Han LY, Talbot K, Wilson RS et al (2008) Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease. Am J Pathol 173:1488-1495
14. Li Z, Jo J, Jia JM, Lo SC, Whitcomb DJ et al (2010) Caspase-3 activation via mitochondria is required for long-term depression and AMPA receptor internalization. Cell 141:859-871
15. Mattson MP, Keller JN, Begley JG (1998) Evidence for synaptic apoptosis. Exp Neurol 153:35-48 (Pubitemid 28452295)
16. Mattson MP, Partin J, Begley JG (1998) Amyloid beta-peptide induces apoptosis-related events in synapses and dendrites. Brain Res 807:167-176 (Pubitemid 29005249)
17. D'Amelio M, Cavallucci V, Middei S, Marchetti C, Pacioni S et al (2011) Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease. Nat Neurosci 14:69-76
18. Glantz LA, Gilmore JH, Lieberman JA, Jarskog LF (2006) Apoptotic mechanisms and the synaptic pathology of schizophrenia. Schizophr Res 81:47-63 (Pubitemid 41817206)
19. Bomar JM, Benke PJ, Slattery EL, Puttagunta R, Taylor LP et al (2003) Mutations in a novel gene encoding a CRAL-TRIO domain cause human Cayman ataxia and ataxia/dystonia in the jittery mouse. Nat Genet 35:264-269 (Pubitemid 37363181)
20. Xiao J, Ledoux MS (2005) Caytaxin deficiency causes generalized dystonia in rats. Brain Res Mol Brain Res 141:181-192 (Pubitemid 41608700)
21. LeDoux MS, Lorden JF (2002) Abnormal spontaneous and harmaline- stimulated Purkinje cell activity in the awake genetically dystonic rat. Exp Brain Res 145:457-467
22. Hayakawa Y, Itoh M, Yamada A, Mitsuda T, Nakagawa T (2007) Expression and localization of Cayman ataxia-related protein, Caytaxin, is regulated in a developmental- and spatial-dependent manner. Brain Res 1129:100-109 (Pubitemid 46048773)
23. Buschdorf JP, Li Chew L, Zhang B, Cao Q, Liang FY et al (2006) Brain-specific BNIP-2-homology protein Caytaxin relocalises glutaminase to neurite terminals and reduces glutamate levels. J Cell Sci 119:3337-3350 (Pubitemid 44405219)
24. Buschdorf JP, Chew LL, Soh UJ, Liou YC, Low BC (2008) Nerve growth factor stimulates interaction of Cayman ataxia protein BNIP-H/Caytaxin with peptidyl-prolyl isomerase Pin1 in differentiating neurons. PLoS One 3:e2686
25. McAllister AK (2007) Dynamic aspects of CNS synapse formation. Annu Rev Neurosci 30:425-450
26. Sudhof TC (2004) The synaptic vesicle cycle. Annu Rev Neurosci 27:509-547
27. Rohrbough J, Broadie K (2005) Lipid regulation of the synaptic vesicle cycle. Nat Rev Neurosci 6:139-150 (Pubitemid 40188948)
28. Jovanovic JN, Benfenati F, Siow YL, Sihra TS, Sanghera JS et al (1996) Neurotrophins stimulate phosphorylation of synapsin I by MAP kinase and regulate synapsin I-actin interactions. Proc Natl Acad Sci USA 93:3679-3683 (Pubitemid 26127596)
29. Jovanovic JN, Czernik AJ, Fienberg AA, Greengard P, Sihra TS (2000) Synapsins as mediators of BDNF-enhanced neurotransmitter release. Nat Neurosci 3:323-329 (Pubitemid 30185481)
30. Giachello CN, Fiumara F, Giacomini C, Corradi A, Milanese C et al (2010) MAPK/Erk-dependent phosphorylation of synapsin mediates formation of functional synapses and short-term homosynaptic plasticity. J Cell Sci 123:881-893
31. Kushner SA, Elgersma Y, Murphy GG, Jaarsma D, van Woerden GM et al (2005) Modulation of presynaptic plasticity and learning by the H-ras/extracellular signal-regulated kinase/synapsin I signaling pathway. J Neurosci 25:9721-9734 (Pubitemid 41510912)
32. Vara H, Onofri F, Benfenati F, Sassoe-Pognetto M, Giustetto M (2009) ERK activation in axonal varicosities modulates presynaptic plasticity in the CA3 region of the hippocampus through synapsin I. Proc Natl Acad Sci USA 106:9872-9877
33. Cui Y, Costa RM, Murphy GG, Elgersma Y, Zhu Y et al (2008) Neurofibromin regulation of ERK signaling modulates GABA release and learning. Cell 135:549-560
34. Zhou YT, Guy GR, Low BC (2005) BNIP-2 induces cell elongation and membrane protrusions by interacting with Cdc42 via a unique Cdc42-binding motif within its BNIP-2 and Cdc42GAP homology domain. Exp Cell Res 303:263-274 (Pubitemid 40126261)
35. Thornberry NA, Rano TA, Peterson EP, Rasper DM, Timkey T et al (1997) A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis. J Biol Chem 272:17907-17911 (Pubitemid 27306365)
36. Caballero-Benitez A, Moran J (2003) Caspase activation pathways induced by staurosporine and low potassium: role of caspase-2. J Neurosci Res 71:383-396 (Pubitemid 36159497)
37. Aoyama T, Hata S, Nakao T, Tanigawa Y, Oka C et al (2009) Cayman ataxia protein caytaxin is transported by kinesin along neurites through binding to kinesin light chains. J Cell Sci 122:4177-4185
38. Wen W, Meinkoth JL, Tsien RY, Taylor SS (1995) Identification of a signal for rapid export of proteins from the nucleus. Cell 82:463-473
39. Valencia CA, Cotten SW, Liu R (2007) Cleavage of BNIP-2 and BNIP-XL by caspases. Biochem Biophys Res Commun 364:495-501 (Pubitemid 350026494)
40. Gulyaeva NV, Kudryashov IE, Kudryashova IV (2003) Caspase activity is essential for long-term potentiation. J Neurosci Res 73:853-864 (Pubitemid 37071740)
41. Morabito MA, Sheng M, Tsai LH (2004) Cyclin-dependent kinase 5 phosphorylates the N-terminal domain of the postsynaptic density protein PSD-95 in neurons. J Neurosci 24:865-876 (Pubitemid 38146597)
42. tom Dieck S, Sanmarti-Vila L, Langnaese K, Richter K, Kindler S et al (1998) Bassoon, a novel zinc-finger CAG/glutamine-repeat protein selectively localized at the active zone of presynaptic nerve terminals. J Cell Biol 142:499-509