Colocalization of protein kinase a with adenylyl cyclase enhances protein kinase a activity during induction of Long-Lasting Long-Term-Potentiation

PLoS Computational Biology

Volumn 7, Issue 6, 2011, Pages

  Kim, Myungsook ^a   Park, Alan Jung ^b   Havekes, Robbert ^b   Chay, Andrew ^a   Guercio, Leonardo Antonio ^b   Oliveira, Rodrigo Freire ^a   Abel, Ted ^b   Blackwell, Kim T ^a  

^a GEORGE MASON UNIVERSITY   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES; ESTERS; MOLECULES; SIGNALING; STOCHASTIC MODELS; STOCHASTIC SYSTEMS;

A-KINASE-ANCHORING PROTEINS; ADENYLYL CYCLASE; ANCHORINGS; COLOCALIZATION; INPUT PATTERNS; LONG LASTING; LONG-TERM POTENTIATIONS; PROTEIN KINASE A; SPATIAL INPUTS; TEMPORAL AND SPATIAL;

PHOSPHORYLATION;

ADENYLATE CYCLASE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; DOPAMINE 1 RECEPTOR; FORSKOLIN; GLUTAMATE RECEPTOR 1; PHOSPHODIESTERASE; CALCIUM; CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN; DOPAMINE; HT 31 PROTEIN, SYNTHETIC; PROTEIN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INACTIVATION; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; HIPPOCAMPAL CA1 REGION; LONG TERM POTENTIATION; MOUSE; NONHUMAN; POSTSYNAPTIC POTENTIAL; PROTEIN DEPHOSPHORYLATION; PROTEIN DOMAIN; PYRAMIDAL NERVE CELL; SIGNAL TRANSDUCTION; SIMULATION; STOCHASTIC MODEL; ANIMAL; BIOLOGICAL MODEL; COMPUTER SIMULATION; DIFFUSION; DRUG EFFECT; ENZYME SPECIFICITY; METABOLISM; PHYSIOLOGY; STATISTICS; SYNAPTIC POTENTIAL;

A KINASE ANCHOR PROTEINS; ADENYLATE CYCLASE; ANIMALS; CA1 REGION, HIPPOCAMPAL; CALCIUM; COMPUTER SIMULATION; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DIFFUSION; DOPAMINE; FORSKOLIN; LONG-TERM POTENTIATION; MICE; MODELS, BIOLOGICAL; PROTEINS; PYRAMIDAL CELLS; STOCHASTIC PROCESSES; SUBSTRATE SPECIFICITY; SYNAPTIC POTENTIALS;

EID: 79959823902     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1002084     Document Type: Article

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