Two-stage design of sequencing studies for testing association with rare variants

Human Heredity

Volumn 71, Issue 4, 2011, Pages 209-220

  Yang, Fan ^a   Thomas, Duncan C ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Burden indices; Multiple rare variants; Next generation sequencing; Study design

Indexed keywords

ALLELE; ARTICLE; COST BENEFIT ANALYSIS; GENETIC VARIABILITY; GENOME; SAMPLE SIZE; SEQUENCE ANALYSIS; SIMULATION; SINGLE NUCLEOTIDE POLYMORPHISM;

ALLELES; CASE-CONTROL STUDIES; COMPUTER SIMULATION; GENETIC ASSOCIATION STUDIES; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MODELS, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ANALYSIS;

EID: 79959818670     PISSN: 00015652     EISSN: 14230062     Source Type: Journal    
DOI: 10.1159/000328193     Document Type: Article

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