Early potassium channel blockade improves sepsis-induced organ damage and cardiovascular dysfunction

British Journal of Pharmacology

Volumn 163, Issue 6, 2011, Pages 1289-1301

  Sordi, R ^a   Fernandes, D ^b   Heckert, B T ^a   Assreuy, J ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^b STATE UNIVERSITY OF PONTA GROSSA   (Brazil)

Author keywords

glibenclamide; nitric oxide; NOS 2; peritonitis; potassium channels; sepsis; septic shock; tetraethylammonium; vascular hyporesponsiveness

Indexed keywords

CREATININE; GLIBENCLAMIDE; GLUCOSE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; LACTIC ACID; MYELOPEROXIDASE; NITRIC OXIDE; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; TETRYLAMMONIUM; TUMOR NECROSIS FACTOR ALPHA; UREA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; BLOOD LEVEL; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DISEASE EXACERBATION; EARLY INTERVENTION; ENZYME ACTIVITY; FEMALE; GLUCOSE BLOOD LEVEL; HEMODYNAMIC PARAMETERS; HYPERGLYCEMIA; HYPOGLYCEMIA; HYPOTENSION; INFLAMMATION; LACTATE BLOOD LEVEL; LUNG; MORTALITY; NONHUMAN; ORGAN INJURY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SEPSIS; SURVIVAL; THIGH;

ANIMALS; BLOOD PRESSURE; CARDIOVASCULAR DISEASES; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLYBURIDE; HEART RATE; LONGEVITY; LUNG; MUSCLE, SKELETAL; NITRIC OXIDE SYNTHASE TYPE II; POTASSIUM CHANNEL BLOCKERS; RATS; RATS, WISTAR; SEPSIS; TETRAETHYLAMMONIUM; VASOCONSTRICTOR AGENTS;

EID: 79959770731     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01324.x     Document Type: Article

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