Development of Novel Peptidomimetics Containing a Vinyl Sulfone Moiety as Proteasome Inhibitors

ChemMedChem

Volumn 6, Issue 7, 2011, Pages 1228-1237

  Ettari, Roberta ^a   Bonaccorso, Cinzia ^a   Micale, Nicola ^a   Heindl, Cornelia ^b   Schirmeister, Tanja ^b   Calabrò, Maria Luisa ^a   Grasso, Silvana ^a   Zappalà, Maria ^a  

^a UNIVERSITY OF MESSINA   (Italy)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Chymotrypsin like activity; Inhibitors; Peptidomimetics; Proteasome; Vinyl sulfones

Indexed keywords

CATHEPSIN B; CATHEPSIN L; CHYMOTRYPSIN A; LEUCINE; PANCREAS ENZYME; PEPTIDOMIMETIC AGENT; PHENYLALANINE; PROTEASOME INHIBITOR; UNCLASSIFIED DRUG; VINYL SULFONE;

AMINO ACID SEQUENCE; ARTICLE; BIOAVAILABILITY; DRUG DESIGN; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME DEGRADATION; ERYTHROCYTE; HUMAN; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CATHEPSIN B; CATHEPSIN L; CATTLE; CHYMOTRYPSIN; HUMANS; PEPTIDOMIMETICS; PROTEASE INHIBITORS; PROTEASOME ENDOPEPTIDASE COMPLEX; SULFONES;

EID: 79959757218     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201100093     Document Type: Article

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