New, relevant information and innovative interventions in the management of acne

Giornale Italiano di Dermatologia e Venereologia

Volumn 146, Issue 3, 2011, Pages 197-210

  Danby, F W ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

Acne; Actinic damage; Dairy; Hidradenitis suppurativa; High glycemic load; Hyperin sulinemia; IGF 1; Rosacea; Unroofing

Indexed keywords

ANABOLIC AGENT; ANDROGEN RECEPTOR; ANDROGEN RECEPTOR ANTAGONIST; ANTIBIOTIC AGENT; CORTEXOLONE 17ALPHA PROPIONATE; CORTICOSTEROID; CROTAMITON; CYPROTERONE ACETATE; DAPSONE; DROSPIRENONE; DUTASTERIDE; FINASTERIDE; FLUCONAZOLE; GESTAGEN; GROWTH HORMONE; INSULIN; ISOTRETINOIN; ITRACONAZOLE; IVERMECTIN; KETOCONAZOLE; METRONIDAZOLE; NICOTINE; NONSTEROID ANTIINFLAMMATORY AGENT; PERMETHRIN; RESORCINOL; RETINOID; SOMATOMEDIN C; UNCLASSIFIED DRUG;

ACNE; ACNE VULGARIS; ANTIINFLAMMATORY ACTIVITY; ARTICLE; COMEDO; CREAM; DAIRY PRODUCT; DRUG DISTRIBUTION; DRUG SYNTHESIS; DRUG WITHDRAWAL; FURUNCULOSIS; GEL; HORMONAL REGULATION; HUMAN; INFLAMMATION; LIFESTYLE MODIFICATION; MEDICAL PRACTICE; PATHOGENESIS; PATIENT CARE; PHOTODYNAMIC THERAPY; PHOTOTHERAPY; PROTEIN PHOSPHORYLATION; ROSACEA; SINGLE DRUG DOSE; SUPPURATIVE HIDRADENITIS; TREATMENT INDICATION; TREATMENT RESPONSE; UNSPECIFIED SIDE EFFECT; VALIDATION PROCESS;

EID: 79959720335     PISSN: 03920488     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (67)

1. Kligman A. Letter of Welcome. 2nd International Conference "Sebaceous Gland, Acne Rosacea and Related Disorders - Basic and Clinical Research, Clinical Entities and Treatment. Rome September 2008.
2. Gandarillas A. Epidermal differentiation, apoptosis, and senescence: common pathways? Exp Gerontol 2000;35:53-62.
3. Danby FW. Pilosebaceous dynamics. 2010 [Internet]. [cited 2011 March 22]. Available at: http://www.acnemilk.com
4. Chen WC, Zouboulis CC. Hormones and the pilosebaceous unit. Dermatoendocrinol 2009;1:81-6.
5. Melnik BC, Schmitz G. Role of insulin, insulin-like growth factor-1, hyperglycaemic food and milk consumption in the pathogenesis of acne vulgaris. Exp Dermatol 2009;18:833-41.
6. Melnik BC. Acneigenic stimuli converge in phosphoinositol-3 kinase/Akt/FoxO1 signal transduction. J Clin Exp Dermatol 2010;1:101:1-8.
7. Melnik BC. The role of transcription factor FoxO1 in the pathogenesis of acne vulgaris and the mode of isotretinoin action. G Ital Dermatol Venereol 2010;145:559-72.
8. Melnik BC. FoxO1 - the key for the pathogenesis and therapy of acne? J Dtsch Dermatol Ges 2010;8:105-14.
9. Koldovsky O. Hormones in milk. Vitam Horm 1995;50:77-149.
10. Holmes MD, Pollak MN, Willett WC, Hankinson SE. Dietary correlates of plasma insulin-like growth factor I and insulin-like growth factor binding protein 3 concentrations. Cancer Epidemiol Biomarkers Prev 2002;11:852-61. (Pubitemid 35014888)
11. Honegger A, Humbel RE. Insulin-like growth factors I and II in fetal and adult bovine serum. Purification, primary structures, and immunological cross-reactivities. J Biol Chem 1986;261:569-75. (Pubitemid 16161708)
12. Hoppe C, Molgaard C, Juul A, Michaelsen KF. High intakes of skimmed milk, but not meat, increase serum IGF-1 and IGFBP-3 in eight-year-old boys. Eur J Clin Nutr 2004;58:1211-6. (Pubitemid 39264017)
13. Hoppe C, Molgaard C, Dalum C, Vaag A, Michaelsen KF. Differential effects of casein versus whey on fasting plasma levels of insulin, IGF-1 and IGF-1/IGFBP-3: results from a randomized 7-day supplementation study in prepubertal boys. Eur J Clin Nutr 2009;63:1076-83.
14. Harvard School of Public Health, McGill University. Milk, Hormones and Human Health. [cited 2011 March 22]. Available at URL:http://milksymposium. mcgill.ca/summary/. AccessedOctober 23, 2006.
15. Hoppe C, Molgaard C, Vaag A, Barkholt V, Michaelsen KF. High intakes of milk, but not meat, increase s-insulin and insulin resistance in 8-year-old boy. Eur J Clin Nutr 2005;59:393-8. (Pubitemid 40403293)
16. Hoyt G, Hickey MS, Cordain L. Dissociation of the glycaemic and insulinaemic responses to whole and skimmed milk. Br J Nutr 2005;93:175-7.
17. Hoppe C, Molgaard C, Dalum C, Vaag A, Michaelsen KF. Differential effects of casein versus whey on fasting plasma levels of insulin, IGF-1 and IGF-1/IGFBP-3: results from a randomized 7-day supplementation study in prepubertal boys. Eur J Clin Nutr 2009;63:1076-83.
18. Smith RN, Mann NJ, Braue A, Makelainen H, Varigos GA. The effect of a high-protein, low glycemic-load diet versus a conventional, high glycemic-load diet on biochemical parameters associated with acne vulgaris: a randomized, investigator-masked, controlled trial. J Am Acad Dermatol 2007;57:247-56. (Pubitemid 47048861)
19. Adebamowo CA, Spiegelman D, Danby FW, Frazier AL, Willett WC, Holmes MD. High school dietary dairy intake and teenage acne. J Am Acad Dermatol 2005;52:207-14.
20. Adebamowo CA, Spiegelman D, Berkey CS et al. Milk consumption and acne in adolescent girls. Dermatol Online J 2006;12:1.
21. Adebamowo CA, Spiegelman D, Berkey CS, Danby FW, Rockett HH, Colditz GA et al. Milk consumption and acne in teenaged boys. J Am Acad Dermatol 2008;58:787-93.
22. Smith RN, Mann NJ, Braue A, Makelainen H, Varigos GA. The effect of a high-protein, low glycemic-load diet versus a conventional, high glycemic-load diet on biochemical parameters associated with acne vulgaris: a randomized, investigator-masked, controlled trial. J Am Acad Dermatol 2007;57:247-56. (Pubitemid 47048861)
23. Smith RN, Mann NJ, Braue A, Makelainen H, Varigos GA. A low-glycemic-load diet improves symptoms in acne vulgaris patients: a randomized controlled trial. Am J Clin Nutr 2007;86:107-15. (Pubitemid 47041599)
24. Cordain L, Lindeberg S, Hurtado M, Hill K, Eaton SB, Brand-Miller J. Acne vulgaris: a disease of Western civilization. Arch Dermatol 2002;138:1584-90.
25. Hana A, Booken D, Henrich C, Gratchev A, Maas-Szabowski N, Goerdt S et al. Functional significance of non-neuronal acetylcholine in skin epithelia. Life Sci 2007;80:2214-20. (Pubitemid 46818279)
26. Konig A, Lehmann C, Rompel R, Happle R. Cigarette smoking as a triggering factor of hidradenitis suppurativa. Dermatology 1999;198:261-4. (Pubitemid 29281414)
27. Revuz J. HS patients' frequently asked questions. In: Jemec G, Revuz J, Leyden J, editors. Hidradenitis Suppurativa. Berlin: Springer; 2006. p. 191.
28. Capitanio B, Sinagra JL, Bordignon V, Cordiali FP, Picardo M, Zouboulis CC. Underestimated clinical features of postadolescent acne. J Am Acad Dermatol 2010;63:782-8.
29. Dickey RP. Managing contraceptive pill patients. 12 ed. Edmonton, AL: EMIS Inc.; 1998.
30. Rubig A. Drospirenone: a new cardiovascular-active progestin with antialdosterone and antiandrogenic properties. Climacteric 2003;6(Suppl 3):49-54. (Pubitemid 38112893)
31. Archer B, Irwin D, Jensen K, Johnson ME, Rorie J. Depot medroxy-progesterone. Management of side-effects commonly associated with its contraceptive use. J Nurse Midwifery 1997;42:104-11. (Pubitemid 127749889)
32. Kumar N, Koide SS, Tsong Y, Sundaram K. Nestorone: a progestin with a unique pharmacological profile. Steroids 2000;65:629-36.
33. Celasco G, Moro L, Bozzella R, Ferraboschi P, Bartorelli L, Quattrocchi C et al. Biological profile of cortexolone 17alpha-propionate (CB-03-01), a new topical and peripherally selective androgen antagonist. Arzneimittelforschung 2004;54:881-6.
34. Cortexolone Phase 1 Clinical Trial. 9-2-2008. 1-27-2011.
35. Degitz K, Placzek M, Arnold B, Schmidt H, Plewig G. Congenital adrenal hyperplasia and acne in male patients. Br J Dermatol 2003;148:1263-6. (Pubitemid 36819231)
36. Thiboutot D, Martin P, Volikos L, Gilliland K. Oxidative activity of the type 2 isozyme of 17beta-hydroxysteroid dehydrogenase (17beta-HSD) predominates in human sebaceous glands. J Invest Dermatol 1998;111:390-5. (Pubitemid 28400082)
37. Searles GE. Daily oral finasteride 5 mg for hidradenitis suppurativa. Canadian Derm Assoc Ann Conf 2010.
38. Ganceviciene R, Graziene V, Fimmel S, Zouboulis CC. Involvement of the corticotropin-releasing hormone system in the pathogenesis of acne vulgaris. Br J Dermatol 2009;160:345-52.
39. Ayala AR, Pushkas J, Higley JD, Ronsaville D, Gold PW, Chrousos GP et al. Behavioral, adrenal, and sympathetic responses to long-term administration of an oral corticotropin-releasing hormone receptor antagonist in a primate stress paradigm. J Clin Endocrinol Metab 2004;89:5729-37. (Pubitemid 39518466)
40. Darling JA, Laing AH, Harkness RA. A survey of the steroids in cows' milk. J Endocrinol 1974;62:291-7.
41. Belvedere P, Gabai G, Dalla Valle L, Accorsi P, Trivoletti M, Colombo L et al. Occurrence of steroidogenic enzymes in the bovine mammary gland at different functional stages. J Steroid Biochem Mol Biol 1996;59:339-47. (Pubitemid 27037940)
42. Kurokawa I, Danby FW, Ju Q, Wang X, Xiang LF, Xia L et al. New developments in our understanding of acne pathogenesis and treatment. Exp Dermatol 2009;18:821-32.
43. Zouboulis CC. Is acne vulgaris a genuine inflammatory disease? Dermatology 2001;203:277-9.
44. Zouboulis CC, Eady A, Philpott M, Goldsmith LA, Orfanos C, Cunliffe WC et al. What is the pathogenesis of acne? Exp Dermatol 2005;14:143-52.
45. Zouboulis CC. [Modern aspects of acne pathogenesis]. J Dtsch Dermatol Ges 2010;8(Suppl 1):S7-14.
46. Funt LS. Oral ibuprofen and minocycline for the treatment of resistant acne vulgaris. J Am Acad Dermatol 1985;13:524-5. (Pubitemid 15016505)
47. Kircik LH. Harnessing the anti-inflammatory effects of topical dapsone for management of acne. J Drugs Dermatol 2010;9:667-71.
48. Ganceviciene R, Zouboulis CC. Isotretinoin: state of the art treatment for acne vulgaris. J Dtsch Dermatol Ges 2010;8(Suppl 1):S47-S59.
49. Lee JW, Yoo KH, Park KY, Han TY, Li K, Seo SJ et al. Effectiveness of Conventional, Low-dose and Intermittent Oral Isotretinoin in the Treatment of Acne: A Randomized, Controlled Comparative study. Br J Dermatol 2010 [Epub ahead of print].
50. Bek-Thomsen M, Lomholt HB, Kilian M. Acne is not associated with yet-uncultured bacteria. J Clin Microbiol 2008;46:3355-60.
51. Leeming JP, Holland KT, Cunliffe WJ. The microbial ecology of pilosebaceous units isolated from human skin. J Gen Microbiol 1984;130:803-7. (Pubitemid 14132785)
52. Eichenfield L, Jorizzo J, Dirschka T, Taub AF, Lynde C, Graeber M et al. Treatment of 2,453 acne vulgaris patients aged 12-17 years with the fixed-dose adapalene-benzoyl peroxide combination topical gel: efficacy and safety. J Drugs Dermatol 2010;9:1395-401.
53. Sugita T, Miyamoto M, Tsuboi R, Takatori K, Ikeda R, Nishikawa A. In vitro activities of azole antifungal agents against Propionibacterium acnes isolated from patients with acne vulgaris. Biol Pharm Bull 2010;33:125-7.
54. Sur R, Babad JM, Garay M, Liebel FT, Southall MD. Anti-inflammatory activity of sertaconazole nitrate is mediated via activation of a p38-COX-2-PGE2 pathway. J Invest Dermatol 2008;128:336-44.
55. Venturoli S, Fabbri R, DaI Prato L, Mantovani B, Capelli M, Magrini O et al. Ketoconazole therapy for women with acne and/or hirsutism. J Clin Endocrinol Metab 1990;71:335-9.
56. Gniadecki R, Jemec GB. Lipid raft-enriched stem cell-like keratinocytes in the epidermis, hair follicles and sinus tracts in hidradenitis suppurativa. Exp Dermatol 2004;13:361-3. (Pubitemid 38877555)
57. Danby FW, Margesson LJ. Hidradenitis suppurativa. Dermatol Clin 2010;28:779-93.
58. Boer J, Jemec GB. Resorcinol peels as a possible self-treatment of painful nodules in hidradenitis suppurativa. Clin Exp Dermatol 2010;35:36-40.
59. Wortsman X, Jemec GB. Real-time compound imaging ultrasound of hidradenitis suppurativa. Dermatol Surg 2007;33:1340-2. (Pubitemid 47624087)
60. van der Zee HH, Prens EP, Boer J. Deroofing: a tissue-saving surgical technique for the treatment of mild to moderate hidradenitis suppurativa lesions. J Am Acad Dermatol 2010;63:475-80.
61. Mullins JF, McCash WB, Boudreau RF. Treatment of chronic hidradenitis suppurativa: surgical modification. Postgrad Med 1959;26:805-8.
62. Danby FW. Commentary: unroofing for hidradenitis suppurativa, why and how. J Am Acad Dermatol 2010;63:481-3.
63. Amano M, Grant A, Kerdel FA. A prospective open-label clinical trial of adalimumab for the treatment of hidradenitis suppurativa. Int J Dermatol 2010;49:950-5.
64. Fardet L, Dupuy A, Kerob D, Levy A, Allez M, Begon E et al. Infliximab for severe hidradenitis suppurativa: transient clinical efficacy in 7 consecutive patients. J Am Acad Dermatol 2007;56:624-8. (Pubitemid 46400174)
65. Grant A, Gonzalez T, Montgomery MO, Cardenas V, Kerdel FA. Infliximab therapy for patients with moderate to severe hidradenitis suppurativa: a randomized, double-blind, placebo-controlled cross-over trial. J Am Acad Dermatol 2010;62:205-17.
66. Lee RA, Dommasch E, Treat J, Sciacca-Kirby J, Chachkin S, Williams J et al. A prospective clinical trial of open-label etanercept for the treatment of hidradenitis suppurativa. J Am Acad Dermatol 2009;60:565-73.
67. RxDerm. Anecdotal Therapy of Acne Rosacea. 2011. Ref Type: Internet Communication. Limited access Discussion Group rxderm-l@ucdavis.edu