Hexokinase II acts through UCP3 to suppress mitochondrial reactive oxygen species production and maintain aerobic respiration

Biochemical Journal

Volumn 437, Issue 2, 2011, Pages 301-311

  Mailloux, Ryan J ^a   Dumouchel, Tyler ^b   Aguer, Céline ^a   Dekemp, Rob ^b   Beanlands, Rob ^b   Harper, Mary Ellen ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

^b UNIVERSITY OF OTTAWA HEART INSTITUTE   (Canada)

Author keywords

Mitochondrion; Position emission tomography; Reactive oxygen species; Skelatal muscle; Uncoupling protein 3

Indexed keywords

GLUCOSE; HEXOKINASE; HEXOKINASE 2; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 3;

AEROBIC METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CATABOLISM; GLYCOLYSIS; MALE; MOUSE; MUSCLE MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION;

ANIMALS; CELL RESPIRATION; FOOD; GLUCOSE; GLYCOLYSIS; HEK293 CELLS; HEXOKINASE; HUMANS; ION CHANNELS; MICE; MICE, KNOCKOUT; MITOCHONDRIA, MUSCLE; MITOCHONDRIAL PROTEINS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

MUS;

EID: 79959716502     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20110571     Document Type: Article

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