Toll-like receptor 7/8 agonist resiquimod induces late preconditioning in neonatal cardiac myocytes

Acta Pharmacologica Sinica

Volumn 32, Issue 5, 2011, Pages 565-572

  Wang, Yong Yi ^a   Liu, Sha ^a   Lian, Feng ^a   Yang, Wen Gang ^a   Xue, Song ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

anoxia reoxygenation; cardioprotection; late preconditioning; reactive oxygen species; resiquimod; toll like receptor

Indexed keywords

ACETYLCYSTEINE; CYCLOHEXAMIDE; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LACTATE DEHYDROGENASE; MALONALDEHYDE; MESSENGER RNA; PROTEIN SYNTHESIS INHIBITOR; REACTIVE OXYGEN METABOLITE; RESIQUIMOD; RNA 18S; SMALL INTERFERING RNA; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG ANTAGONISM; ENZYME ACTIVITY; GEL MOBILITY SHIFT ASSAY; GENETIC TRANSFECTION; HEART MUSCLE CELL; HEART PROTECTION; NEWBORN; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ANIMALS, NEWBORN; CARDIOTONIC AGENTS; CELL HYPOXIA; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE KNOCKDOWN TECHNIQUES; HYPOXIA-INDUCIBLE FACTOR 1; IMIDAZOLES; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MYOCYTES, CARDIAC; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; OXYGEN; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 8;

EID: 79959715428     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2011.6     Document Type: Article

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