The incidence of positive results in the mouse lymphoma TK assay (MLA) in pharmaceutical screening and their prediction by MultiCase MC4PC

Mutagenesis

Volumn 26, Issue 4, 2011, Pages 529-532

  Fellows, Michael D ^a   Boyer, Scott ^b   O'Donovan, Michael R ^a  

^a ASTRAZENECA   (United Kingdom)

^b ASTRAZENECA R AND D   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BACTERIAL MUTATION; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DRUG SCREENING; FALSE POSITIVE RESULT; GENOTOXICITY; IN VITRO STUDY; LYMPHOMA; MOUSE; MOUSE LYMPHOMA TK ASSAY; NONHUMAN; PHARMACEUTICAL CARE; PREDICTION; PRIORITY JOURNAL; RAT; SENSITIVITY AND SPECIFICITY;

ANIMALS; CARCINOGENICITY TESTS; CELL LINE, TUMOR; DRUG EVALUATION, PRECLINICAL; LYMPHOMA; MICE; SOFTWARE; STRUCTURE-ACTIVITY RELATIONSHIP; THYMIDINE KINASE;

BACTERIA (MICROORGANISMS);

EID: 79959700975     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/ger012     Document Type: Article

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