메뉴 건너뛰기




Volumn 65, Issue 3, 2011, Pages 168-174

The Ras signaling pathway mediates cetuximab resistance in nasopharyngeal carcinoma

Author keywords

Cetuximab; Drug resistance; Nasopharyngeal carcinoma

Indexed keywords

CETUXIMAB; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN C FOS; PROTEIN KINASE B; RAS PROTEIN; SHORT HAIRPIN RNA; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR RELA;

EID: 79959640290     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2011.02.005     Document Type: Article
Times cited : (11)

References (29)
  • 1
    • 0027722067 scopus 로고
    • Precise mapping of the EGF receptor gene on the human chromosome 7p12 using an improved fish technique
    • Wang Y., Minoshima S., Shimizu N. Precise mapping of the EGF receptor gene on the human chromosome 7p12 using an improved fish technique. Jpn J Hum Genet 1993, 38:399-406.
    • (1993) Jpn J Hum Genet , vol.38 , pp. 399-406
    • Wang, Y.1    Minoshima, S.2    Shimizu, N.3
  • 2
    • 65649086838 scopus 로고    scopus 로고
    • Cetuximab in combination with irinotecan/5-fluorouracil/folinic acid (FOLFIRI) in the initial treatment of metastatic colorectal cancer: a multicentre two-part phase I/II study
    • Raoul J.L., Van Laethem J.L., Peeters M., Brezault C., Husseini F., Cals L., et al. Cetuximab in combination with irinotecan/5-fluorouracil/folinic acid (FOLFIRI) in the initial treatment of metastatic colorectal cancer: a multicentre two-part phase I/II study. BMC Cancer 2009, 9:112.
    • (2009) BMC Cancer , vol.9 , pp. 112
    • Raoul, J.L.1    Van Laethem, J.L.2    Peeters, M.3    Brezault, C.4    Husseini, F.5    Cals, L.6
  • 3
    • 47149084688 scopus 로고    scopus 로고
    • Epidermal growth factor receptor monoclonal antibodies for the treatment of metastatic colorectal cancer
    • Jean G.W., Shah S.R. Epidermal growth factor receptor monoclonal antibodies for the treatment of metastatic colorectal cancer. Pharmacotherapy 2008, 28:742-754.
    • (2008) Pharmacotherapy , vol.28 , pp. 742-754
    • Jean, G.W.1    Shah, S.R.2
  • 6
    • 20644435370 scopus 로고    scopus 로고
    • Multicenter, phase II study of cetuximab in combination with carboplatin in patients with recurrent or metastatic nasopharyngeal carcinoma
    • Chan A.T., Hsu M.M., Goh B.C., Hui E.P., Liu T.W., Millward M.J., et al. Multicenter, phase II study of cetuximab in combination with carboplatin in patients with recurrent or metastatic nasopharyngeal carcinoma. J Clin Oncol 2005, 23:3568-3576.
    • (2005) J Clin Oncol , vol.23 , pp. 3568-3576
    • Chan, A.T.1    Hsu, M.M.2    Goh, B.C.3    Hui, E.P.4    Liu, T.W.5    Millward, M.J.6
  • 7
    • 32144433159 scopus 로고    scopus 로고
    • Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
    • Bonner J.A., Harari P.M., Giralt J., Azarnia N., Shin D.M., Cohen R.B., et al. Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 2006, 354:567-578.
    • (2006) N Engl J Med , vol.354 , pp. 567-578
    • Bonner, J.A.1    Harari, P.M.2    Giralt, J.3    Azarnia, N.4    Shin, D.M.5    Cohen, R.B.6
  • 9
    • 77956882253 scopus 로고    scopus 로고
    • Development of cetuximab-resistant human nasopharyngeal carcinoma cell lines and mechanisms of drug resistance
    • Zuo Q., Shi M., Li L., Chen J., Luo R. Development of cetuximab-resistant human nasopharyngeal carcinoma cell lines and mechanisms of drug resistance. Biomed Pharmacother 2010, 64:550-558.
    • (2010) Biomed Pharmacother , vol.64 , pp. 550-558
    • Zuo, Q.1    Shi, M.2    Li, L.3    Chen, J.4    Luo, R.5
  • 10
    • 66549099437 scopus 로고    scopus 로고
    • Primary colon cancer: ESMO clinical recommendations for diagnosis, adjuvant treatment and follow-up
    • Van Cutsem E., Oliveira J. Primary colon cancer: ESMO clinical recommendations for diagnosis, adjuvant treatment and follow-up. Ann Oncol 2009, 20(Suppl. 4):49-50.
    • (2009) Ann Oncol , vol.20 , Issue.4 SUPPL. , pp. 49-50
    • Van Cutsem, E.1    Oliveira, J.2
  • 11
    • 0029831041 scopus 로고    scopus 로고
    • Quantitative immunohistochemical analysis of transforming growth factor-alpha and epidermal growth factor receptor in patients with squamous cell carcinoma of the head and neck
    • Rubin Grandis J., Melhem M.F., Barnes E.L., Tweardy D.J. Quantitative immunohistochemical analysis of transforming growth factor-alpha and epidermal growth factor receptor in patients with squamous cell carcinoma of the head and neck. Cancer 1996, 78:1284-1292.
    • (1996) Cancer , vol.78 , pp. 1284-1292
    • Rubin Grandis, J.1    Melhem, M.F.2    Barnes, E.L.3    Tweardy, D.J.4
  • 12
    • 1242338149 scopus 로고    scopus 로고
    • Epidermal growth factor receptor and response of head-and-neck carcinoma to therapy
    • Ang K.K., Andratschke N.H., Milas L. Epidermal growth factor receptor and response of head-and-neck carcinoma to therapy. Int J Radiat Oncol Biol Phys 2004, 58:959-965.
    • (2004) Int J Radiat Oncol Biol Phys , vol.58 , pp. 959-965
    • Ang, K.K.1    Andratschke, N.H.2    Milas, L.3
  • 13
    • 0032478998 scopus 로고    scopus 로고
    • Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival
    • Rubin Grandis J., Melhem M.F., Gooding W.E., Day R., Holst V.A., Wagener M.M., et al. Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival. J Natl Cancer Inst 1998, 90:824-832.
    • (1998) J Natl Cancer Inst , vol.90 , pp. 824-832
    • Rubin Grandis, J.1    Melhem, M.F.2    Gooding, W.E.3    Day, R.4    Holst, V.A.5    Wagener, M.M.6
  • 14
    • 68949088035 scopus 로고    scopus 로고
    • Improving response rates to EGFR-targeted therapies for head and neck squamous cell carcinoma: candidate predictive biomarkers and combination treatment with Src inhibitors
    • Egloff A.M., Grandis J.R. Improving response rates to EGFR-targeted therapies for head and neck squamous cell carcinoma: candidate predictive biomarkers and combination treatment with Src inhibitors. J Oncol 2009, 2009:896407.
    • (2009) J Oncol , vol.2009 , pp. 896407
    • Egloff, A.M.1    Grandis, J.R.2
  • 15
    • 77954085990 scopus 로고    scopus 로고
    • PIK3CA mutation occurs in nasopharyngeal carcinoma but does not significantly influence the disease-specific survival
    • Chou C.C., Chou M.J., Tzen C.Y. PIK3CA mutation occurs in nasopharyngeal carcinoma but does not significantly influence the disease-specific survival. Med Oncol 2009, 26:322-326.
    • (2009) Med Oncol , vol.26 , pp. 322-326
    • Chou, C.C.1    Chou, M.J.2    Tzen, C.Y.3
  • 16
    • 0033528836 scopus 로고    scopus 로고
    • Genetic alterations in Ki-ras and Ha-ras genes in juvenile nasopharyngeal angiofibromas and head and neck cancer
    • Coutinho C.M., Bassini A.S., Gutierrez L.G., Butugan O., Kowalski L.P., Brentani M.M., et al. Genetic alterations in Ki-ras and Ha-ras genes in juvenile nasopharyngeal angiofibromas and head and neck cancer. Sao Paulo Med J 1999, 117:113-120.
    • (1999) Sao Paulo Med J , vol.117 , pp. 113-120
    • Coutinho, C.M.1    Bassini, A.S.2    Gutierrez, L.G.3    Butugan, O.4    Kowalski, L.P.5    Brentani, M.M.6
  • 19
    • 0037062951 scopus 로고    scopus 로고
    • RNA interference
    • Hannon G.J. RNA interference. Nature 2002, 418:244-251.
    • (2002) Nature , vol.418 , pp. 244-251
    • Hannon, G.J.1
  • 20
    • 33646253672 scopus 로고    scopus 로고
    • Akt signaling and cancer: surviving but not moving on
    • Toker A., Yoeli-Lerner M. Akt signaling and cancer: surviving but not moving on. Cancer Res 2006, 66:3963-3966.
    • (2006) Cancer Res , vol.66 , pp. 3963-3966
    • Toker, A.1    Yoeli-Lerner, M.2
  • 22
    • 0033607633 scopus 로고    scopus 로고
    • Phosphorylation and regulation of Raf by Akt (protein kinase B)
    • Zimmermann S., Moelling K. Phosphorylation and regulation of Raf by Akt (protein kinase B). Science 1999, 286:1741-1744.
    • (1999) Science , vol.286 , pp. 1741-1744
    • Zimmermann, S.1    Moelling, K.2
  • 23
    • 77956341456 scopus 로고    scopus 로고
    • Cell transformation by v-Rel reveals distinct roles of AP-1 family members in Rel/NF-kappaB oncogenesis
    • Liss A.S., Tiwari R., Kralova J., Bose H.R. Cell transformation by v-Rel reveals distinct roles of AP-1 family members in Rel/NF-kappaB oncogenesis. Oncogene 2010, 29:4925-4937.
    • (2010) Oncogene , vol.29 , pp. 4925-4937
    • Liss, A.S.1    Tiwari, R.2    Kralova, J.3    Bose, H.R.4
  • 24
    • 0027938445 scopus 로고
    • C-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases
    • Minden A., Lin A., Smeal T., Derijard B., Cobb M., Davis R., et al. c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases. Mol Cell Biol 1994, 14:6683-6688.
    • (1994) Mol Cell Biol , vol.14 , pp. 6683-6688
    • Minden, A.1    Lin, A.2    Smeal, T.3    Derijard, B.4    Cobb, M.5    Davis, R.6
  • 25
    • 0037405649 scopus 로고    scopus 로고
    • Bile acid regulation of C/EBPbeta, CREB, and c-Jun function, via the extracellular signal-regulated kinase and c-Jun NH2-terminal kinase pathways, modulates the apoptotic response of hepatocytes
    • Qiao L., Han S.I., Fang Y., Park J.S., Gupta S., Gilfor D., et al. Bile acid regulation of C/EBPbeta, CREB, and c-Jun function, via the extracellular signal-regulated kinase and c-Jun NH2-terminal kinase pathways, modulates the apoptotic response of hepatocytes. Mol Cell Biol 2003, 23:3052-3066.
    • (2003) Mol Cell Biol , vol.23 , pp. 3052-3066
    • Qiao, L.1    Han, S.I.2    Fang, Y.3    Park, J.S.4    Gupta, S.5    Gilfor, D.6
  • 26
    • 0029874138 scopus 로고    scopus 로고
    • The NF-kappa B and I kappa B proteins: new discoveries and insights
    • Baldwin A.S. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu Rev Immunol 1996, 14:649-683.
    • (1996) Annu Rev Immunol , vol.14 , pp. 649-683
    • Baldwin, A.S.1
  • 27
    • 0028971289 scopus 로고
    • Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation
    • Verma I.M., Stevenson J.K., Schwarz E.M., Van Antwerp D., Miyamoto S. Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation. Genes Dev 1995, 9:2723-2735.
    • (1995) Genes Dev , vol.9 , pp. 2723-2735
    • Verma, I.M.1    Stevenson, J.K.2    Schwarz, E.M.3    Van Antwerp, D.4    Miyamoto, S.5
  • 28
    • 77955072957 scopus 로고    scopus 로고
    • Phenethyl isothiocyanate inhibits migration and invasion of human gastric cancer AGS cells through suppressing MAPK and NF-kappaB signal pathways
    • Yang M.D., Lai K.C., Lai T.Y., Hsu S.C., Kuo C.L., Yu C.S., et al. Phenethyl isothiocyanate inhibits migration and invasion of human gastric cancer AGS cells through suppressing MAPK and NF-kappaB signal pathways. Anticancer Res 2010, 30:2135-2143.
    • (2010) Anticancer Res , vol.30 , pp. 2135-2143
    • Yang, M.D.1    Lai, K.C.2    Lai, T.Y.3    Hsu, S.C.4    Kuo, C.L.5    Yu, C.S.6
  • 29
    • 77956682914 scopus 로고    scopus 로고
    • Pneumocystis cell wall beta-glucan stimulates calcium-dependent signaling of IL-8 secretion by human airway epithelial cells
    • Carmona E.M., Lamont J.D., Xue A., Wylam M., Limper A.H. Pneumocystis cell wall beta-glucan stimulates calcium-dependent signaling of IL-8 secretion by human airway epithelial cells. Respir Res 2010, 11:95.
    • (2010) Respir Res , vol.11 , pp. 95
    • Carmona, E.M.1    Lamont, J.D.2    Xue, A.3    Wylam, M.4    Limper, A.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.