-
1
-
-
0027722067
-
Precise mapping of the EGF receptor gene on the human chromosome 7p12 using an improved fish technique
-
Wang Y., Minoshima S., Shimizu N. Precise mapping of the EGF receptor gene on the human chromosome 7p12 using an improved fish technique. Jpn J Hum Genet 1993, 38:399-406.
-
(1993)
Jpn J Hum Genet
, vol.38
, pp. 399-406
-
-
Wang, Y.1
Minoshima, S.2
Shimizu, N.3
-
2
-
-
65649086838
-
Cetuximab in combination with irinotecan/5-fluorouracil/folinic acid (FOLFIRI) in the initial treatment of metastatic colorectal cancer: a multicentre two-part phase I/II study
-
Raoul J.L., Van Laethem J.L., Peeters M., Brezault C., Husseini F., Cals L., et al. Cetuximab in combination with irinotecan/5-fluorouracil/folinic acid (FOLFIRI) in the initial treatment of metastatic colorectal cancer: a multicentre two-part phase I/II study. BMC Cancer 2009, 9:112.
-
(2009)
BMC Cancer
, vol.9
, pp. 112
-
-
Raoul, J.L.1
Van Laethem, J.L.2
Peeters, M.3
Brezault, C.4
Husseini, F.5
Cals, L.6
-
3
-
-
47149084688
-
Epidermal growth factor receptor monoclonal antibodies for the treatment of metastatic colorectal cancer
-
Jean G.W., Shah S.R. Epidermal growth factor receptor monoclonal antibodies for the treatment of metastatic colorectal cancer. Pharmacotherapy 2008, 28:742-754.
-
(2008)
Pharmacotherapy
, vol.28
, pp. 742-754
-
-
Jean, G.W.1
Shah, S.R.2
-
4
-
-
54949085398
-
K-ras mutations and benefit from cetuximab in advanced colorectal cancer
-
Karapetis C.S., Khambata-Ford S., Jonker D.J., O'Callaghan C.J., Tu D., Tebbutt N.C., et al. K-ras mutations and benefit from cetuximab in advanced colorectal cancer. N Engl J Med 2008, 359:1757-1765.
-
(2008)
N Engl J Med
, vol.359
, pp. 1757-1765
-
-
Karapetis, C.S.1
Khambata-Ford, S.2
Jonker, D.J.3
O'Callaghan, C.J.4
Tu, D.5
Tebbutt, N.C.6
-
5
-
-
70450195266
-
Implications for KRAS status and EGFR-targeted therapies in metastatic CRC
-
Normanno N., Tejpar S., Morgillo F., De Luca A., Van Cutsem E., Ciardiello F. Implications for KRAS status and EGFR-targeted therapies in metastatic CRC. Nat Rev Clin Oncol 2009, 6:519-527.
-
(2009)
Nat Rev Clin Oncol
, vol.6
, pp. 519-527
-
-
Normanno, N.1
Tejpar, S.2
Morgillo, F.3
De Luca, A.4
Van Cutsem, E.5
Ciardiello, F.6
-
6
-
-
20644435370
-
Multicenter, phase II study of cetuximab in combination with carboplatin in patients with recurrent or metastatic nasopharyngeal carcinoma
-
Chan A.T., Hsu M.M., Goh B.C., Hui E.P., Liu T.W., Millward M.J., et al. Multicenter, phase II study of cetuximab in combination with carboplatin in patients with recurrent or metastatic nasopharyngeal carcinoma. J Clin Oncol 2005, 23:3568-3576.
-
(2005)
J Clin Oncol
, vol.23
, pp. 3568-3576
-
-
Chan, A.T.1
Hsu, M.M.2
Goh, B.C.3
Hui, E.P.4
Liu, T.W.5
Millward, M.J.6
-
7
-
-
32144433159
-
Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
-
Bonner J.A., Harari P.M., Giralt J., Azarnia N., Shin D.M., Cohen R.B., et al. Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 2006, 354:567-578.
-
(2006)
N Engl J Med
, vol.354
, pp. 567-578
-
-
Bonner, J.A.1
Harari, P.M.2
Giralt, J.3
Azarnia, N.4
Shin, D.M.5
Cohen, R.B.6
-
8
-
-
51649085865
-
Platinum-based chemotherapy plus cetuximab in head and neck cancer
-
Vermorken J.B., Mesia R., Rivera F., Remenar E., Kawecki A., Rottey S., et al. Platinum-based chemotherapy plus cetuximab in head and neck cancer. N Engl J Med 2008, 359:1116-1127.
-
(2008)
N Engl J Med
, vol.359
, pp. 1116-1127
-
-
Vermorken, J.B.1
Mesia, R.2
Rivera, F.3
Remenar, E.4
Kawecki, A.5
Rottey, S.6
-
9
-
-
77956882253
-
Development of cetuximab-resistant human nasopharyngeal carcinoma cell lines and mechanisms of drug resistance
-
Zuo Q., Shi M., Li L., Chen J., Luo R. Development of cetuximab-resistant human nasopharyngeal carcinoma cell lines and mechanisms of drug resistance. Biomed Pharmacother 2010, 64:550-558.
-
(2010)
Biomed Pharmacother
, vol.64
, pp. 550-558
-
-
Zuo, Q.1
Shi, M.2
Li, L.3
Chen, J.4
Luo, R.5
-
10
-
-
66549099437
-
Primary colon cancer: ESMO clinical recommendations for diagnosis, adjuvant treatment and follow-up
-
Van Cutsem E., Oliveira J. Primary colon cancer: ESMO clinical recommendations for diagnosis, adjuvant treatment and follow-up. Ann Oncol 2009, 20(Suppl. 4):49-50.
-
(2009)
Ann Oncol
, vol.20
, Issue.4 SUPPL.
, pp. 49-50
-
-
Van Cutsem, E.1
Oliveira, J.2
-
11
-
-
0029831041
-
Quantitative immunohistochemical analysis of transforming growth factor-alpha and epidermal growth factor receptor in patients with squamous cell carcinoma of the head and neck
-
Rubin Grandis J., Melhem M.F., Barnes E.L., Tweardy D.J. Quantitative immunohistochemical analysis of transforming growth factor-alpha and epidermal growth factor receptor in patients with squamous cell carcinoma of the head and neck. Cancer 1996, 78:1284-1292.
-
(1996)
Cancer
, vol.78
, pp. 1284-1292
-
-
Rubin Grandis, J.1
Melhem, M.F.2
Barnes, E.L.3
Tweardy, D.J.4
-
12
-
-
1242338149
-
Epidermal growth factor receptor and response of head-and-neck carcinoma to therapy
-
Ang K.K., Andratschke N.H., Milas L. Epidermal growth factor receptor and response of head-and-neck carcinoma to therapy. Int J Radiat Oncol Biol Phys 2004, 58:959-965.
-
(2004)
Int J Radiat Oncol Biol Phys
, vol.58
, pp. 959-965
-
-
Ang, K.K.1
Andratschke, N.H.2
Milas, L.3
-
13
-
-
0032478998
-
Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival
-
Rubin Grandis J., Melhem M.F., Gooding W.E., Day R., Holst V.A., Wagener M.M., et al. Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival. J Natl Cancer Inst 1998, 90:824-832.
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 824-832
-
-
Rubin Grandis, J.1
Melhem, M.F.2
Gooding, W.E.3
Day, R.4
Holst, V.A.5
Wagener, M.M.6
-
14
-
-
68949088035
-
Improving response rates to EGFR-targeted therapies for head and neck squamous cell carcinoma: candidate predictive biomarkers and combination treatment with Src inhibitors
-
Egloff A.M., Grandis J.R. Improving response rates to EGFR-targeted therapies for head and neck squamous cell carcinoma: candidate predictive biomarkers and combination treatment with Src inhibitors. J Oncol 2009, 2009:896407.
-
(2009)
J Oncol
, vol.2009
, pp. 896407
-
-
Egloff, A.M.1
Grandis, J.R.2
-
15
-
-
77954085990
-
PIK3CA mutation occurs in nasopharyngeal carcinoma but does not significantly influence the disease-specific survival
-
Chou C.C., Chou M.J., Tzen C.Y. PIK3CA mutation occurs in nasopharyngeal carcinoma but does not significantly influence the disease-specific survival. Med Oncol 2009, 26:322-326.
-
(2009)
Med Oncol
, vol.26
, pp. 322-326
-
-
Chou, C.C.1
Chou, M.J.2
Tzen, C.Y.3
-
16
-
-
0033528836
-
Genetic alterations in Ki-ras and Ha-ras genes in juvenile nasopharyngeal angiofibromas and head and neck cancer
-
Coutinho C.M., Bassini A.S., Gutierrez L.G., Butugan O., Kowalski L.P., Brentani M.M., et al. Genetic alterations in Ki-ras and Ha-ras genes in juvenile nasopharyngeal angiofibromas and head and neck cancer. Sao Paulo Med J 1999, 117:113-120.
-
(1999)
Sao Paulo Med J
, vol.117
, pp. 113-120
-
-
Coutinho, C.M.1
Bassini, A.S.2
Gutierrez, L.G.3
Butugan, O.4
Kowalski, L.P.5
Brentani, M.M.6
-
18
-
-
41849088475
-
The roles of MAPKs in disease
-
Lawrence M.C., Jivan A., Shao C., Duan L., Goad D., Zaganjor E., et al. The roles of MAPKs in disease. Cell Res 2008, 18:436-442.
-
(2008)
Cell Res
, vol.18
, pp. 436-442
-
-
Lawrence, M.C.1
Jivan, A.2
Shao, C.3
Duan, L.4
Goad, D.5
Zaganjor, E.6
-
19
-
-
0037062951
-
RNA interference
-
Hannon G.J. RNA interference. Nature 2002, 418:244-251.
-
(2002)
Nature
, vol.418
, pp. 244-251
-
-
Hannon, G.J.1
-
20
-
-
33646253672
-
Akt signaling and cancer: surviving but not moving on
-
Toker A., Yoeli-Lerner M. Akt signaling and cancer: surviving but not moving on. Cancer Res 2006, 66:3963-3966.
-
(2006)
Cancer Res
, vol.66
, pp. 3963-3966
-
-
Toker, A.1
Yoeli-Lerner, M.2
-
21
-
-
1642617693
-
PI3K/Akt signalling pathway and cancer
-
Fresno Vara J.A., Casado E., de Castro J., Cejas P., Belda-Iniesta C., Gonzalez-Baron M. PI3K/Akt signalling pathway and cancer. Cancer Treat Rev 2004, 30:193-204.
-
(2004)
Cancer Treat Rev
, vol.30
, pp. 193-204
-
-
Fresno Vara, J.A.1
Casado, E.2
de Castro, J.3
Cejas, P.4
Belda-Iniesta, C.5
Gonzalez-Baron, M.6
-
22
-
-
0033607633
-
Phosphorylation and regulation of Raf by Akt (protein kinase B)
-
Zimmermann S., Moelling K. Phosphorylation and regulation of Raf by Akt (protein kinase B). Science 1999, 286:1741-1744.
-
(1999)
Science
, vol.286
, pp. 1741-1744
-
-
Zimmermann, S.1
Moelling, K.2
-
23
-
-
77956341456
-
Cell transformation by v-Rel reveals distinct roles of AP-1 family members in Rel/NF-kappaB oncogenesis
-
Liss A.S., Tiwari R., Kralova J., Bose H.R. Cell transformation by v-Rel reveals distinct roles of AP-1 family members in Rel/NF-kappaB oncogenesis. Oncogene 2010, 29:4925-4937.
-
(2010)
Oncogene
, vol.29
, pp. 4925-4937
-
-
Liss, A.S.1
Tiwari, R.2
Kralova, J.3
Bose, H.R.4
-
24
-
-
0027938445
-
C-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases
-
Minden A., Lin A., Smeal T., Derijard B., Cobb M., Davis R., et al. c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases. Mol Cell Biol 1994, 14:6683-6688.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 6683-6688
-
-
Minden, A.1
Lin, A.2
Smeal, T.3
Derijard, B.4
Cobb, M.5
Davis, R.6
-
25
-
-
0037405649
-
Bile acid regulation of C/EBPbeta, CREB, and c-Jun function, via the extracellular signal-regulated kinase and c-Jun NH2-terminal kinase pathways, modulates the apoptotic response of hepatocytes
-
Qiao L., Han S.I., Fang Y., Park J.S., Gupta S., Gilfor D., et al. Bile acid regulation of C/EBPbeta, CREB, and c-Jun function, via the extracellular signal-regulated kinase and c-Jun NH2-terminal kinase pathways, modulates the apoptotic response of hepatocytes. Mol Cell Biol 2003, 23:3052-3066.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 3052-3066
-
-
Qiao, L.1
Han, S.I.2
Fang, Y.3
Park, J.S.4
Gupta, S.5
Gilfor, D.6
-
26
-
-
0029874138
-
The NF-kappa B and I kappa B proteins: new discoveries and insights
-
Baldwin A.S. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu Rev Immunol 1996, 14:649-683.
-
(1996)
Annu Rev Immunol
, vol.14
, pp. 649-683
-
-
Baldwin, A.S.1
-
27
-
-
0028971289
-
Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation
-
Verma I.M., Stevenson J.K., Schwarz E.M., Van Antwerp D., Miyamoto S. Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation. Genes Dev 1995, 9:2723-2735.
-
(1995)
Genes Dev
, vol.9
, pp. 2723-2735
-
-
Verma, I.M.1
Stevenson, J.K.2
Schwarz, E.M.3
Van Antwerp, D.4
Miyamoto, S.5
-
28
-
-
77955072957
-
Phenethyl isothiocyanate inhibits migration and invasion of human gastric cancer AGS cells through suppressing MAPK and NF-kappaB signal pathways
-
Yang M.D., Lai K.C., Lai T.Y., Hsu S.C., Kuo C.L., Yu C.S., et al. Phenethyl isothiocyanate inhibits migration and invasion of human gastric cancer AGS cells through suppressing MAPK and NF-kappaB signal pathways. Anticancer Res 2010, 30:2135-2143.
-
(2010)
Anticancer Res
, vol.30
, pp. 2135-2143
-
-
Yang, M.D.1
Lai, K.C.2
Lai, T.Y.3
Hsu, S.C.4
Kuo, C.L.5
Yu, C.S.6
-
29
-
-
77956682914
-
Pneumocystis cell wall beta-glucan stimulates calcium-dependent signaling of IL-8 secretion by human airway epithelial cells
-
Carmona E.M., Lamont J.D., Xue A., Wylam M., Limper A.H. Pneumocystis cell wall beta-glucan stimulates calcium-dependent signaling of IL-8 secretion by human airway epithelial cells. Respir Res 2010, 11:95.
-
(2010)
Respir Res
, vol.11
, pp. 95
-
-
Carmona, E.M.1
Lamont, J.D.2
Xue, A.3
Wylam, M.4
Limper, A.H.5
|