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Volumn 28, Issue 6, 2008, Pages 742-754

Epidermal growth factor receptor monoclonal antibodies for the treatment of metastatic colorectal cancer

Author keywords

Adverse events; Cetuximab; EGFR; Epidermal growth factor receptor; Metastatic colorectal cancer; Monoclonal antibodies; Panitumumab

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; BEVACIZUMAB; CAPECITABINE; CETUXIMAB; DIPHENHYDRAMINE; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; FLUOROURACIL; FOLINIC ACID; IRINOTECAN; MEMBRANE PROTEIN; OXALIPLATIN; PANITUMUMAB;

EID: 47149084688     PISSN: 02770008     EISSN: None     Source Type: Journal    
DOI: 10.1592/phco.28.6.742     Document Type: Review
Times cited : (85)

References (56)
  • 1
    • 33947593200 scopus 로고    scopus 로고
    • American Cancer Society, Atlanta: American Cancer Society;
    • American Cancer Society. Cancer facts and figures 2007. Atlanta: American Cancer Society; 2007.
    • (2007) Cancer facts and figures 2007
  • 3
    • 17644427902 scopus 로고    scopus 로고
    • American Cancer Society, Atlanta: American Cancer Society;
    • American Cancer Society. Cancer facts and figures 2006. Atlanta: American Cancer Society; 2006.
    • (2006) Cancer facts and figures 2006
  • 4
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004;350:2335-42.
    • (2004) N Engl J Med , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 5
    • 0035135378 scopus 로고    scopus 로고
    • Irinotecan plus fluorouracil/leucovorin for metastatic colorectal cancer: A new survival standard
    • Saltz LB, Douilard JY, Pirotta N, et al. Irinotecan plus fluorouracil/leucovorin for metastatic colorectal cancer: a new survival standard. Oncologist 2001;6:81-91.
    • (2001) Oncologist , vol.6 , pp. 81-91
    • Saltz, L.B.1    Douilard, J.Y.2    Pirotta, N.3
  • 6
    • 1842569206 scopus 로고    scopus 로고
    • A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer
    • Goldberg RM, Sargent DJ, Morton RF, et al. A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer. J Clin Oncol 2004;22:23-30.
    • (2004) J Clin Oncol , vol.22 , pp. 23-30
    • Goldberg, R.M.1    Sargent, D.J.2    Morton, R.F.3
  • 7
    • 1842471336 scopus 로고    scopus 로고
    • Signaling through the epidermal growth factor receptor during the development of malignancy
    • Grandis JR, Sok JC. Signaling through the epidermal growth factor receptor during the development of malignancy. Pharmacol Ther 2004;102:37-46.
    • (2004) Pharmacol Ther , vol.102 , pp. 37-46
    • Grandis, J.R.1    Sok, J.C.2
  • 8
    • 33749018813 scopus 로고    scopus 로고
    • Clinical implications of the mechanism of epidermal growth factor receptor inhibitors
    • Marshall J. Clinical implications of the mechanism of epidermal growth factor receptor inhibitors. Cancer 2006;107:1207-18.
    • (2006) Cancer , vol.107 , pp. 1207-1218
    • Marshall, J.1
  • 9
    • 1642533527 scopus 로고    scopus 로고
    • Cetuximab in the treatment of metastatic colorectal cancer
    • Reynolds NA, Wagstaff AJ. Cetuximab in the treatment of metastatic colorectal cancer. Drugs 2004;64:109-18.
    • (2004) Drugs , vol.64 , pp. 109-118
    • Reynolds, N.A.1    Wagstaff, A.J.2
  • 10
    • 33747340480 scopus 로고    scopus 로고
    • Targeting the epidermal growth factor receptor in the treatment of colorectal cancer: State of the art
    • Diasio RB, Fourie J. Targeting the epidermal growth factor receptor in the treatment of colorectal cancer: state of the art. Drugs 2006;66:1441-63.
    • (2006) Drugs , vol.66 , pp. 1441-1463
    • Diasio, R.B.1    Fourie, J.2
  • 11
    • 33751083588 scopus 로고    scopus 로고
    • Panitumumab: In the treatment of metastatic colorectal cancer
    • Hoy SM, Wagstaff AJ. Panitumumab: in the treatment of metastatic colorectal cancer. Drugs 2006;66:2005-16.
    • (2006) Drugs , vol.66 , pp. 2005-2016
    • Hoy, S.M.1    Wagstaff, A.J.2
  • 12
    • 0034754136 scopus 로고    scopus 로고
    • Epidermal growth factor receptor biology (IMC-C225)
    • Kim ES, Khuri FR, Herbst RS. Epidermal growth factor receptor biology (IMC-C225). Curr Opin Oncol 2001;13:506-13.
    • (2001) Curr Opin Oncol , vol.13 , pp. 506-513
    • Kim, E.S.1    Khuri, F.R.2    Herbst, R.S.3
  • 13
    • 47149088312 scopus 로고    scopus 로고
    • Amgen. Vectibix (panitumumab) package insert. Thousand Oaks, CA; 2006
    • Amgen. Vectibix (panitumumab) package insert. Thousand Oaks, CA; 2006.
  • 14
    • 47149114598 scopus 로고    scopus 로고
    • ImClone Systems Incorporated, Bristol-Myers Squibb. Erbitux (cetuximab) package insert. New York, NY, and Princeton, NJ; 2006
    • ImClone Systems Incorporated, Bristol-Myers Squibb. Erbitux (cetuximab) package insert. New York, NY, and Princeton, NJ; 2006.
  • 15
    • 0027290650 scopus 로고
    • Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies
    • Baselga J, Norton L, Masui H, et al. Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies. J Natl Cancer Inst 1993;85:1327-33.
    • (1993) J Natl Cancer Inst , vol.85 , pp. 1327-1333
    • Baselga, J.1    Norton, L.2    Masui, H.3
  • 16
    • 0032904485 scopus 로고    scopus 로고
    • Antitumor activity of sequential treatment with topotecan and anti-epidermal growth factor receptor monoclonal antibody c225
    • Ciardiello F, Bianco R, Damiano V, et al. Antitumor activity of sequential treatment with topotecan and anti-epidermal growth factor receptor monoclonal antibody c225. Clin Cancer Res 1999;5:909-16.
    • (1999) Clin Cancer Res , vol.5 , pp. 909-916
    • Ciardiello, F.1    Bianco, R.2    Damiano, V.3
  • 17
    • 0036094194 scopus 로고    scopus 로고
    • Enhanced antitumor activity of anti-epidermal growth factor receptor monoclonal antibody IMC-C225 in combination with irinotecan (CPT-11) against human colorectal tumor xenografts
    • Prewett MC, Hooper AT, Bassi R, Ellis LM, Waksal HW, Hicklin DJ. Enhanced antitumor activity of anti-epidermal growth factor receptor monoclonal antibody IMC-C225 in combination with irinotecan (CPT-11) against human colorectal tumor xenografts. Clin Cancer Res 2002;8:994-1003.
    • (2002) Clin Cancer Res , vol.8 , pp. 994-1003
    • Prewett, M.C.1    Hooper, A.T.2    Bassi, R.3    Ellis, L.M.4    Waksal, H.W.5    Hicklin, D.J.6
  • 18
    • 19244366949 scopus 로고    scopus 로고
    • Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin
    • Baselga J, Pfister D, Cooper MR, et al. Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin. J Clin Oncol 2000;18:904-14.
    • (2000) J Clin Oncol , vol.18 , pp. 904-914
    • Baselga, J.1    Pfister, D.2    Cooper, M.R.3
  • 19
    • 0036899229 scopus 로고    scopus 로고
    • Monoclonal antibodies as therapeutics in oncology
    • Trikha M, Yan L, Nakada MT. Monoclonal antibodies as therapeutics in oncology. Curr Opin Biotechnol 2002;13:609-14.
    • (2002) Curr Opin Biotechnol , vol.13 , pp. 609-614
    • Trikha, M.1    Yan, L.2    Nakada, M.T.3
  • 20
    • 4143050397 scopus 로고    scopus 로고
    • Safety, pharmacokinetics, and activity of ABX-EGF, a fully human anti-epidermal growth factor receptor monoclonal antibody in patients with metastatic renal cell cancer
    • Rowinsky EK, Schwartz GH, Gollob JA, et al. Safety, pharmacokinetics, and activity of ABX-EGF, a fully human anti-epidermal growth factor receptor monoclonal antibody in patients with metastatic renal cell cancer. J Clin Oncol 2004;22:3003-15.
    • (2004) J Clin Oncol , vol.22 , pp. 3003-3015
    • Rowinsky, E.K.1    Schwartz, G.H.2    Gollob, J.A.3
  • 23
    • 33645802841 scopus 로고    scopus 로고
    • In vivo disposition of irinotecan (cpt-11) and its metabolites in combination with the monoclonal antibody cetuximab
    • Ettlinger DE, Mitterhauser M, Wadsak W, et al. In vivo disposition of irinotecan (cpt-11) and its metabolites in combination with the monoclonal antibody cetuximab. Anticancer Res 2006;26:1337-42.
    • (2006) Anticancer Res , vol.26 , pp. 1337-1342
    • Ettlinger, D.E.1    Mitterhauser, M.2    Wadsak, W.3
  • 24
    • 34247480064 scopus 로고    scopus 로고
    • Panitumumab with irinotecan/leucovorin/5-fluorouracil for first-line treatment of metastatic colorectal cancer
    • Berlin J, Posey J, Tchekmedyian S, et al. Panitumumab with irinotecan/leucovorin/5-fluorouracil for first-line treatment of metastatic colorectal cancer. Clin Colorectal Cancer 2007;6:427-32.
    • (2007) Clin Colorectal Cancer , vol.6 , pp. 427-432
    • Berlin, J.1    Posey, J.2    Tchekmedyian, S.3
  • 25
    • 3242720345 scopus 로고    scopus 로고
    • Cetuximab monotherapy and cetuximab plus irinotecan-refractory metastatic colorectal caner
    • Cunningham D, Humblet Y, Siena S, et al. Cetuximab monotherapy and cetuximab plus irinotecan-refractory metastatic colorectal caner. N Engl J Med 2004;351:337-45.
    • (2004) N Engl J Med , vol.351 , pp. 337-345
    • Cunningham, D.1    Humblet, Y.2    Siena, S.3
  • 27
    • 47149086443 scopus 로고    scopus 로고
    • Jonker DJ, Karapetis CS, Moore M, et al. Randomized phase III trial of cetuximab monotherapy plus best supportive care (BSC) versus BSC alone in patients with pretreated metastatic epidermal growth factor (EGFR)-positive colorectal carcinoma: a trial of the National Cancer Institute of Canada Clinical Trials Group (NCIC CTG) and the Australasian Gastro-Intestinal Trials Group (AGITG) [abstract]. In: Program and proceedings of the 2007 annual meeting of the American Association for Cancer Research. Philadelphia, PA: American Association for Cancer Research, 2007:LB-1.
    • Jonker DJ, Karapetis CS, Moore M, et al. Randomized phase III trial of cetuximab monotherapy plus best supportive care (BSC) versus BSC alone in patients with pretreated metastatic epidermal growth factor (EGFR)-positive colorectal carcinoma: a trial of the National Cancer Institute of Canada Clinical Trials Group (NCIC CTG) and the Australasian Gastro-Intestinal Trials Group (AGITG) [abstract]. In: Program and proceedings of the 2007 annual meeting of the American Association for Cancer Research. Philadelphia, PA: American Association for Cancer Research, 2007:LB-1.
  • 28
    • 33645284166 scopus 로고    scopus 로고
    • Cetuximab and irinotecan as third-line therapy in advanced colorectal cancer patients: A single centre phase II trial
    • Vincenzi B, Santini D, Rabitti C, et al. Cetuximab and irinotecan as third-line therapy in advanced colorectal cancer patients: a single centre phase II trial. Br J Cancer 2006;94:792-7.
    • (2006) Br J Cancer , vol.94 , pp. 792-797
    • Vincenzi, B.1    Santini, D.2    Rabitti, C.3
  • 29
    • 2142641698 scopus 로고    scopus 로고
    • Phase II trial of cetuximab in patients with refractory colorectal cancer that express the epidermal growth factor receptor
    • Saltz LB, Meropol NJ, Loehrer PJ, Needle MN, Kopit J, Mayer RJ. Phase II trial of cetuximab in patients with refractory colorectal cancer that express the epidermal growth factor receptor. J Clin Oncol 2004;22:1201-8.
    • (2004) J Clin Oncol , vol.22 , pp. 1201-1208
    • Saltz, L.B.1    Meropol, N.J.2    Loehrer, P.J.3    Needle, M.N.4    Kopit, J.5    Mayer, R.J.6
  • 30
    • 33750615769 scopus 로고    scopus 로고
    • Multicenter phase II and translational study of cetuximab in metastatic colorectal carcinoma refractory to irinotecan, oxaliplatin, and fluoropyrimidines
    • Lenz HJ, Van Cutsem E, Khambata-Ford S, et al. Multicenter phase II and translational study of cetuximab in metastatic colorectal carcinoma refractory to irinotecan, oxaliplatin, and fluoropyrimidines. J Clin Oncol 2006;24:4914-21.
    • (2006) J Clin Oncol , vol.24 , pp. 4914-4921
    • Lenz, H.J.1    Van Cutsem, E.2    Khambata-Ford, S.3
  • 32
    • 34147103678 scopus 로고    scopus 로고
    • Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer
    • Van Cutsem E, Peeters M, Siena S, et al. Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer. J Clin Oncol 2007;25:1658-64.
    • (2007) J Clin Oncol , vol.25 , pp. 1658-1664
    • Van Cutsem, E.1    Peeters, M.2    Siena, S.3
  • 33
    • 47149112816 scopus 로고    scopus 로고
    • Cetuximab in combination with irinotecan/5-fluorouracil (5-FU)/folinic acid (FA) (FOLFIRI) in second and third line treatment of metastatic colorectal cancer (mCRC): Safety and efficacy analysis [abstract]
    • Smith DM, Legoux J, Brunet R, et al. Cetuximab in combination with irinotecan/5-fluorouracil (5-FU)/folinic acid (FA) (FOLFIRI) in second and third line treatment of metastatic colorectal cancer (mCRC): safety and efficacy analysis [abstract]. J Clin Oncol (2006 ASCO annual meeting proceedings) 2006;24(18S, June 20 suppl):3558.
    • J Clin Oncol (2006 ASCO annual meeting proceedings) 2006;24(18S, June 20 suppl):3558
    • Smith, D.M.1    Legoux, J.2    Brunet, R.3
  • 34
    • 35648941728 scopus 로고    scopus 로고
    • Randomized phase II trial of cetuximab, bevacizumab, and irinotecan compared with cetuximab and bevacizumab alone in irinotecan-refractory colorectal cancer: The BOND-2 study
    • Saltz LB, Lenz HJ, Kindler HL, et al. Randomized phase II trial of cetuximab, bevacizumab, and irinotecan compared with cetuximab and bevacizumab alone in irinotecan-refractory colorectal cancer: the BOND-2 study. J Clin Oncol 2007;25:4557-61.
    • (2007) J Clin Oncol , vol.25 , pp. 4557-4561
    • Saltz, L.B.1    Lenz, H.J.2    Kindler, H.L.3
  • 36
    • 47149112052 scopus 로고    scopus 로고
    • Randomized phase III study of irinotecan and 5-FU/LA with or without cetuximab in the first-line treatment of patients with metastatic colorectal cancer (mCRC): The CRYSTAL trial [abstract]
    • Van Cutsem E, Nowacki M, Lang I, et al. Randomized phase III study of irinotecan and 5-FU/LA with or without cetuximab in the first-line treatment of patients with metastatic colorectal cancer (mCRC): the CRYSTAL trial [abstract]. J Clin Oncol (2007 ASCO annual meeting proceedings) 2007;25(18S, June 20 suppl):4000.
    • J Clin Oncol (2007 ASCO annual meeting proceedings) 2007;25(18S, June 20 suppl):4000
    • Van Cutsem, E.1    Nowacki, M.2    Lang, I.3
  • 38
    • 24644457747 scopus 로고    scopus 로고
    • Phase III randomized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: A multicenter study of the gruppo oncologico dell'Italia meridionale
    • Colucci G, Gebbia V, Paoletti G, et al. Phase III randomized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: a multicenter study of the gruppo oncologico dell'Italia meridionale. J Clin Oncol 2005;23:4866-75.
    • (2005) J Clin Oncol , vol.23 , pp. 4866-4875
    • Colucci, G.1    Gebbia, V.2    Paoletti, G.3
  • 39
    • 34249000361 scopus 로고    scopus 로고
    • Falcone A, Ricci S, Brunetti I, et al. Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: the gruppo oncologico nord ovest. J Clin Oncol 2007;25:1670-6.
    • Falcone A, Ricci S, Brunetti I, et al. Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: the gruppo oncologico nord ovest. J Clin Oncol 2007;25:1670-6.
  • 40
    • 33645309877 scopus 로고    scopus 로고
    • FOLFOXIRI (folinic acid, 5-fluorouracil, oxaliplatin and irinotecan) vs FOLFIRI (folinic acid, 5-fluorouracil and irinotecan) as first-line treatment in metastatic colorectal cancer (MCC): A multicentre randomised phase III trial from the hellenic oncology research group (HORG)
    • Souglakos J, Androulakis N, Syrigos K, et al. FOLFOXIRI (folinic acid, 5-fluorouracil, oxaliplatin and irinotecan) vs FOLFIRI (folinic acid, 5-fluorouracil and irinotecan) as first-line treatment in metastatic colorectal cancer (MCC): a multicentre randomised phase III trial from the hellenic oncology research group (HORG). Br J Cancer 2006;94:798-805.
    • (2006) Br J Cancer , vol.94 , pp. 798-805
    • Souglakos, J.1    Androulakis, N.2    Syrigos, K.3
  • 41
    • 34248173883 scopus 로고    scopus 로고
    • Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: Results from the eastern cooperative oncology group study E3200
    • Giantonio BJ, Catalano PJ, Meropol NJ, et al. Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the eastern cooperative oncology group study E3200. J Clin Oncol 2007;25:1539-44.
    • (2007) J Clin Oncol , vol.25 , pp. 1539-1544
    • Giantonio, B.J.1    Catalano, P.J.2    Meropol, N.J.3
  • 42
    • 33644697486 scopus 로고    scopus 로고
    • Cetuximab and irinotecan/5-fluorouracil/folinic acid is a safe combination for the first-line treatment of patients with epidermal growth factor receptor expressing metastatic colorectal carcinoma
    • Folprecht G, Lutz MP, Schoffski P, et al. Cetuximab and irinotecan/5-fluorouracil/folinic acid is a safe combination for the first-line treatment of patients with epidermal growth factor receptor expressing metastatic colorectal carcinoma. Ann Oncol 2006;17:450-6.
    • (2006) Ann Oncol , vol.17 , pp. 450-456
    • Folprecht, G.1    Lutz, M.P.2    Schoffski, P.3
  • 43
    • 47149103901 scopus 로고    scopus 로고
    • XELIRI plus cetuximab versus XELOX plus cetuximab for first-line therapy of metastatic colorectal cancer (CRC): A randomized trial of the AIO CRC study group [abstract]
    • abstract 278
    • Heinemann V, Moosmann N, Vehling-Kaiser U, et al. XELIRI plus cetuximab versus XELOX plus cetuximab for first-line therapy of metastatic colorectal cancer (CRC): a randomized trial of the AIO CRC study group [abstract]. J Clin Oncol (2007 GI-ASCO annual meeting proceedings) 2007:abstract 278.
    • (2007) J Clin Oncol (2007 GI-ASCO annual meeting proceedings)
    • Heinemann, V.1    Moosmann, N.2    Vehling-Kaiser, U.3
  • 45
    • 47149114803 scopus 로고    scopus 로고
    • ClinicalTrials.gov. Clinical trials 2007. Available from www.clinicaltrials.gov. Accessed July 7, 2007.
    • ClinicalTrials.gov. Clinical trials 2007. Available from www.clinicaltrials.gov. Accessed July 7, 2007.
  • 46
    • 39049180071 scopus 로고    scopus 로고
    • CALGB/SWOG 80405: A phase III trial of FOLFIRI or FOLFOX with bevacizumab or cetuximab or both for untreated metastatic adenocarcinoma of the colon or rectum
    • Cancer and Leukemia Group B, Southwest Oncology Group
    • Cancer and Leukemia Group B, Southwest Oncology Group. CALGB/SWOG 80405: a phase III trial of FOLFIRI or FOLFOX with bevacizumab or cetuximab or both for untreated metastatic adenocarcinoma of the colon or rectum. Clin Adv Hematol Oncol 2006;4:452-3.
    • (2006) Clin Adv Hematol Oncol , vol.4 , pp. 452-453
  • 47
    • 33749847753 scopus 로고    scopus 로고
    • Challenges in the use of epidermal growth factor receptor inhibitors in colorectal cancer
    • Van Cutsem E. Challenges in the use of epidermal growth factor receptor inhibitors in colorectal cancer. Oncologist 2006;11:1010-17.
    • (2006) Oncologist , vol.11 , pp. 1010-1017
    • Van Cutsem, E.1
  • 48
    • 20144381957 scopus 로고    scopus 로고
    • Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunochemistry
    • Chung KY, Shia J, Kemeny NE, et al. Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunochemistry. J Clin Oncol 2005;23:1803-10.
    • (2005) J Clin Oncol , vol.23 , pp. 1803-1810
    • Chung, K.Y.1    Shia, J.2    Kemeny, N.E.3
  • 49
    • 33646355483 scopus 로고    scopus 로고
    • New issues on cetuximab mechanism of action in epidermal growth factor receptor-negative colorectal cancer: The role of vascular endothelial growth factor [letter]
    • Vincenzi B, Santini D, Tonini G. New issues on cetuximab mechanism of action in epidermal growth factor receptor-negative colorectal cancer: the role of vascular endothelial growth factor [letter]. J Clin Oncol 2006;24:1957.
    • (2006) J Clin Oncol , vol.24 , pp. 1957
    • Vincenzi, B.1    Santini, D.2    Tonini, G.3
  • 50
    • 47149097332 scopus 로고    scopus 로고
    • Predictive value of skin toxicity severity for response to panitumumab in patients with metastatic colorectal cancer (mCRC): A pooled analysis of five clinical trials [abstract]
    • Berlin J, Van Cutsem E, Peeters M, et al. Predictive value of skin toxicity severity for response to panitumumab in patients with metastatic colorectal cancer (mCRC): a pooled analysis of five clinical trials [abstract]. J Clin Oncol (2007 ASCO annual meeting proceedings) 2007;25(18S, June 20 suppl):4134.
    • J Clin Oncol (2007 ASCO annual meeting proceedings) 2007;25(18S, June 20 suppl):4134
    • Berlin, J.1    Van Cutsem, E.2    Peeters, M.3
  • 52
    • 16644369733 scopus 로고    scopus 로고
    • Practical management of patients with non-small-cell lung cancer treated with gefitinib
    • Shah NT, Kris MG, Pao W, et al. Practical management of patients with non-small-cell lung cancer treated with gefitinib. J Clin Oncol 2005;23:165-74.
    • (2005) J Clin Oncol , vol.23 , pp. 165-174
    • Shah, N.T.1    Kris, M.G.2    Pao, W.3
  • 54
    • 33749034712 scopus 로고    scopus 로고
    • Cetuximab-induced hypomagnesemia in patients with colorectal cancer
    • Fakih MG, Wilding G, Lombardo J. Cetuximab-induced hypomagnesemia in patients with colorectal cancer. Clin Colorectal Cancer 2006;6:152-6.
    • (2006) Clin Colorectal Cancer , vol.6 , pp. 152-156
    • Fakih, M.G.1    Wilding, G.2    Lombardo, J.3
  • 55
    • 34548501422 scopus 로고    scopus 로고
    • Cetuximab plus irinotecan for metastatic colorectal cancer (mCRC): Safety analysis of 800 patients in a randomized phase III trial (EPIC) [abstract]
    • Abubakr Y, Eng C, Pautret V, et al. Cetuximab plus irinotecan for metastatic colorectal cancer (mCRC): safety analysis of 800 patients in a randomized phase III trial (EPIC) [abstract]. J Clin Oncol (2006 ASCO annual meeting proceedings) 2006;24(18S):3556.
    • (2006) J Clin Oncol (2006 ASCO annual meeting proceedings) , vol.24 , Issue.18 S , pp. 3556
    • Abubakr, Y.1    Eng, C.2    Pautret, V.3
  • 56
    • 34250372165 scopus 로고    scopus 로고
    • Treatment with panitumumab after a severe infusion reaction to cetuximab in a patient with metastatic colorectal cancer: A case report
    • Heun J, Holen K. Treatment with panitumumab after a severe infusion reaction to cetuximab in a patient with metastatic colorectal cancer: a case report. Clin Colorectal Cancer 2007;6:529-31.
    • (2007) Clin Colorectal Cancer , vol.6 , pp. 529-531
    • Heun, J.1    Holen, K.2


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