PLA nanoparticles loaded with an active lactone form of hydroxycamptothecin: Development, optimization, and in vitro-in vivo evaluation in mice bearing H22 solid tumor

Drug Development Research

Volumn 72, Issue 4, 2011, Pages 337-345

  Hou, Zhenqing ^a   Zhou, Chunxiao ^a   Luo, Ying ^a   Zhan, Chuanming ^a   Wang, Yixiao ^a   Xie, Liya ^b   Zhang, Qiqing ^a  

^a XIAMEN UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF XIAMEN UNIVERSITY   (China)

Author keywords

dialysis; drug delivery system; hydroxycamptothecin; nanoparticles; PLA

Indexed keywords

CAMPTOTHECIN DERIVATIVE; HYDROXYCAMPTOTHECIN; NANOCARRIER; POLYLACTIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CHEMICAL COMPOSITION; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIALYSIS; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG POTENTIATION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER CANCER; LIVER CELL CARCINOMA; MOLECULAR WEIGHT; MOUSE; NONHUMAN; SURFACE PROPERTY; SUSTAINED DRUG RELEASE; WEIGHT REDUCTION;

EID: 79959635566     PISSN: 02724391     EISSN: 10982299     Source Type: Journal    
DOI: 10.1002/ddr.20435     Document Type: Article

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