Synthesis and antitumor activity studies of some new fused 1,2,4-triazole derivatives carrying 2,4-dichloro-5-fluorophenyl moiety

European Journal of Medicinal Chemistry

Volumn 44, Issue 12, 2009, Pages 5066-5070

  Bhat, K Subrahmanya ^a   Poojary, Boja ^b   Prasad, D Jagadeesh ^b   Naik, Prashantha ^b   Holla, B Shivarama ^c  

^a MANIPAL INSTITUTE OF TECHNOLOGY   (India)

^b MANGALORE UNIVERSITY   (India)

^c Sri Dharmasthala Manjunatheshwara Institute of Technology   (India)

Author keywords

1,2,4 Triazoles; 1,3,4 thiadiazines; 2,4 dichloro 5 fluorophenyl; Anticancer activity; GI50 values

Indexed keywords

1,2,4 TRIAZOLE DERIVATIVE; 3 (2,4 DICHLORO 5 FLUOROPHENYL) 1,2,4 TRIAZOL 5 THIOL; 3 (2,4 DICHLORO 5 FLUOROPHENYL) 6 ARYL 1,2,4 TRIAZOLO[3,4 B] 1,3,4 THIADIAZINE DERIVATIVE; ANTINEOPLASTIC AGENT; BROMIDE; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER SCREENING; CONTROLLED STUDY; CYCLIZATION; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; INFRARED SPECTROMETRY; LEUKEMIA; LUNG NON SMALL CELL CANCER; MASS SPECTROMETRY; MELANOMA; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OVARY CANCER; PROSTATE CANCER;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CHLORINE; DRUG SCREENING ASSAYS, ANTITUMOR; FLUORINE; HUMANS; MOLECULAR STRUCTURE; TRIAZOLES;

EID: 70449687864     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.09.010     Document Type: Article

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