An effective synthetic entry to fused benzimidazoles via iodocyclization

Advanced Synthesis and Catalysis

Volumn 353, Issue 9, 2011, Pages 1429-1437

  Zhang, Xu ^a,b   Zhou, Yu ^a   Wang, Hengshuai ^a   Guo, Diliang ^a,b   Ye, Deju ^a   Xu, Yungen ^b   Jiang, Hualiang ^a   Liu, Hong ^a,b  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

cyclization; fused benzimidazoles; iodine; silver nitrate

Indexed keywords

EID: 79959617196     PISSN: 16154150     EISSN: 16154169     Source Type: Journal    
DOI: 10.1002/adsc.201100038     Document Type: Article

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35. Various acetylenic acids containing oxygen were synthesized from alkynols and ethyl 2-bromoacetate; various substituted acetylenic acids were prepared by Sonogashira coupling reactions between acetylenic ester and iodobenzene or substituted iodobenzenes. The details of operation are given in the Supporting Information.