Linking nutrition, maturation and aging: From thrifty genes to the spendthrift phenotype

Aging

Volumn 3, Issue 2, 2011, Pages 85-93

  Stipp, David ^a  

^a Aging/Impact Journals LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGING; AGRICULTURE; ARTICLE; FEMALE; GENETIC SELECTION; GENOTYPE; HUMAN; MALE; METHODOLOGY; NUTRITIONAL STATUS; PHENOTYPE; PHYSIOLOGY; SEXUAL MATURATION; STARVATION;

AGING; AGRICULTURE; FEMALE; GENOTYPE; HUMANS; MALE; NUTRITIONAL STATUS; PHENOTYPE; SELECTION, GENETIC; SEXUAL MATURATION; STARVATION;

EID: 79959569350     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.100286     Document Type: Note

References (78)

1. Neel J. Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"? Am J Hum Genet 1962;14:353-362.
2. Speakman JR. A nonadaptive scenario explaining the genetic predisposition to obesity: the "predation release" hypothesis. Cell Metab 2007;6(1):5-12.
3. Prentice AM, Rayco-Solon P, Moore SE. Insights from the developing world: thrifty genotypes and thrifty phenotypes. Proc Nutr Soc 2005;64(2):153-161.
4. Prentice A, Hennig B, Fulford A. Evolutionary origins of the obesity epidemic: natural selection of thrifty genes or genetic drift following predation release? Int J Obes (Lond) 2008; 32(11):1607-1610.
5. Frisch R. Body fat, menarche, fitness and fertility. Hum Reprod 1987;2(6):521-533.
6. Williams GC. Pleiotropy, Natural Selection, and the Evolution of Senescence. Evolution 1957;11(4):398-411.
7. Blagosklonny MV. Aging and immortality: quasi-programmed senescence and its pharmacologic inhibition. Cell Cycle 2006;5(18):2087-2102.
8. Knowler W, Pettitt D, Bennett P, Williams R. Diabetes mellitus in the Pima Indians: genetic and evolutionary considerations. Am J Phys Anthropol 1983;62(1):107-114.
9. Dowse G, Zimmet P, Finch C, Collins V. Decline in incidence of epidemic glucose intolerance in Nauruans: implications for the "thrifty genotype". Am J Epidemiol 1991;133(11):1093-1104.
10. Baschetti R. Diabetes epidemic in newly westernized populations: is it due to thrifty genes or to genetically unknown foods? J R Soc Med 1998;91(12):622-625.
11. Christian D. Maps of time: an introduction to big history. University of California Press; 2005.
12. Wells J. Thrift: a guide to thrifty genes, thrifty phenotypes and thrifty norms. Int J Obes (Lond) 2009;33(12):1331-1338.
13. Verginelli F, Aru F, Battista P, Mariani-Costantini R. Nutrigenetics in the light of human evolution. J Nutrigenet Nutrigenomics 2009;2(2):91-9102.
14. Finch CE. The neurotoxicology of hard foraging and fat-melts. Proc Natl Acad Sci U S A 2004;101(52):17887-17888.
15. Wyshak G, Frisch R. Evidence for a secular trend in age of menarche. N Engl J Med 1982;306(17):1033-1035.
16. Frisch R, Revelle R. Height and weight at menarche and a hypothesis of menarche. Arch Dis Child 1971 Oct;46(249):695-701.
17. Chehab F, Lim M, Lu R. Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin. Nat Genet 1996;12(3):318-320.
18. Hassink S, Sheslow D, de Lancey E, Opentanova I, Considine R, Caro J. Serum leptin in children with obesity: relationship to gender and development. Pediatrics 1996;98(2 Pt 1):201-203.
19. Farooqi I, Jebb S, Langmack G, Lawrence E, Cheetham C, Prentice A, Hughes I, McCamish M, O'Rahilly S. Effects of recombinant leptin therapy in a child with congenital leptin deficiency. N Engl J Med 1999;341(12):879-884.
20. Smith BD. The emergence of agriculture. Scientific American Library; 1998.
21. Diamond JM. Guns, germs, and steel: the fates of human societies. W. W. Norton & Company; 1999.
22. Brown P, Konner M. An anthropological perspective on obesity. Ann N Y Acad Sci 1987;499:29-46.
23. Mulder MB. Early maturing Kipsigis women have higher reproductive success than late maturing women and cost more to marry. Behav Ecol Sociobiol 1989;24(3):145-153.
24. Ma H, Du M, Luo X, Chen S, Liu L, Chen R, Zhu C, Xiong F, Li T, Wang W, Liu G, on behalf of the Pubertal Study Group of the Society of Pediatric Endocrinology and Genetic Disease CMA. Onset of Breast and Pubic Hair Development and Menses in Urban Chinese Girls. Pediatrics 2009;124(2):e269-277.
25. Kaplowitz PB. Link between body fat and the timing of puberty. Pediatrics 2008;121 Suppl 3:208-217.
26. Bourguignon J, Rasier G, Lebrethon M, Gerard A, Naveau E, Parent A. Neuroendocrine disruption of pubertal timing and interactions between homeostasis of reproduction and energy balance. Mol Cell Endocrinol 2010;324(1-2):110-120.
27. Davison KK, Susman EJ, Birch LL. Percent body fat at age 5 predicts earlier pubertal development among girls at age 9. Pediatrics 2003;111(4 Pt 1):815-821.
28. Lee JM, Appugliese D, Kaciroti N, Corwyn RF, Bradley RH, Lumeng JC. Weight status in young girls and the onset of puberty. Pediatrics 2007;119(3):624-630.
29. Elks CE, et al. Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nature Genetics 2010;42(12):1077-1087.
30. Lee JM, Kaciroti N, Appugliese D, Corwyn RF, Bradley RH, Lumeng JC. Body mass index and timing of pubertal initiation in boys. Arch Pediatr Adolesc Med 2010;164(2):139-144.
31. He Q, Karlberg J. Bmi in childhood and its association with height gain, timing of puberty, and final height. Pediatr Res 2001;49(2):244-251.
32. Mills J, Shiono P, Shapiro L, Crawford P, Rhoads G. Early growth predicts timing of puberty in boys: results of a 14-year nutrition and growth study. J Pediatr 1986;109(3):543-547.
33. Silventoinen K, Haukka J, Dunkel L, Tynelius P, Rasmussen F. Genetics of pubertal timing and its associations with relative weight in childhood and adult height: the Swedish Young Male Twins Study. Pediatrics 2008;121(4):885-891.
34. Cutler G. The role of estrogen in bone growth and maturation during childhood and adolescence. J Steroid Biochem Mol Biol 1997;61(3-6):141-144.
35. Vizmanos B, Marti-Henneberg C, Cliville R, Moreno A, Fernandez-Ballart J. Age of pubertal onset affects the intensity and duration of pubertal growth peak but not final height. Am J Hum Biol 2001;13(3):409-416.
36. McCay CM, Crowell MF. Prolonging the Life Span. Scientific Monthly 1934;39:405-414.
37. Metcalfe NB, Monaghan P. Growth versus lifespan: perspectives from evolutionary ecology. Exp Gerontol 2003;38(9):935-940.
38. Metcalfe N, Monaghan P. Compensation for a bad start: grow now, pay later? Trends Ecol Evol 2001;16(5):254-260.
39. Ludwig DS. Childhood obesity--the shape of things to come. N. Engl. J. Med 2007;357(23):2325-2327.
40. Dunger DB, Ahmed M, Ong KK. Early and late weight gain and the timing of puberty. Mol Cell Endocrinol 2006;254-255:140-145.
41. Dunger DB, Ahmed M, Ong KK. Effects of obesity on growth and puberty. Best Pract Res Clin Endocrinol Metab 2005;19(3):375-390.
42. Adair L. Size at birth predicts age at menarche. Pediatrics 2001;107(4)
43. Dunger DB, Ahmed M, Ong KK. Early and late weight gain and the timing of puberty. Mol Cell Endocrinol 2006;254-255:140-145.
44. Bateson P, Barker D, Clutton-Brock T, Deb D, D'Udine B, Foley RA, Gluckman P, Godfrey K, Kirkwood T, Lahr MM, McNamara J, Metcalfe NB, Monaghan P, Spencer HG, Sultan SE. Developmental plasticity and human health. Nature 2004;430(6998):419-421.
45. Hales C, Barker D. Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis. Diabetologia 1992;35(7):595-601.
46. Ong KK, Northstone K, Wells JC, Rubin C, Ness AR, Golding J, Dunger DB. Earlier mother's age at menarche predicts rapid infancy growth and childhood obesity. PLoS Med 2007;4(4)
47. Chehab F, Mounzih K, Lu R, Lim M. Early onset of reproductive function in normal female mice treated with leptin. Science 1997;275(5296):88-90.
48. Grasemann C, Wessels HT, Knauer-Fischer S, Richter-Unruh A, Hauffa BP. Increase of serum leptin after short-term pulsatile GnRH administration in children with delayed puberty. Eur J Endocrinol 2004;150(5):691-698.
49. Wilson ME, Fisher J, Chikazawa K, Yoda R, Legendre A, Mook D, Gould KG. Leptin administration increases nocturnal concentrations of luteinizing hormone and growth hormone in juvenile female rhesus monkeys. J Clin Endocrinol Metab 2003;88(10):4874-4883.
50. Matkovic V, Ilich J, Skugor M, Badenhop N, Goel P, Clairmont A, Klisovic D, Nahhas R, Landoll J. Leptin is inversely related to age at menarche in human females. J Clin Endocrinol Metab 1997;82(10):3239-3245.
51. Yura S, Ogawa Y, Sagawa N, Masuzaki H, Itoh H, Ebihara K, Aizawa-Abe M, Fujii S, Nakao K. Accelerated puberty and lateonset hypothalamic hypogonadism in female transgenic skinny mice overexpressing leptin. J Clin Invest 2000;105(6):749-755.
52. Golub MS, Collman GW, Foster PM, Kimmel CA, Rajpert-De Meyts E, Reiter EO, Sharpe RM, Skakkebaek NE, Toppari J. Public health implications of altered puberty timing. Pediatrics 2008;121 Suppl 3:218-230.
53. Frontini M, Srinivasan S, Berenson G. Longitudinal changes in risk variables underlying metabolic Syndrome X from childhood to young adulthood in female subjects with a history of early menarche: the Bogalusa Heart Study. Int J Obes Relat Metab Disord 2003;27(11):1398-1404.
54. Bartke A. Insulin and aging. Cell Cycle 2008;7(21):3338-3343.
55. Piper M, Selman C, McElwee J, Partridge L. Separating cause from effect: how does insulin/IGF signalling control lifespan in worms, flies and mice? J Intern Med 2008;263(2):179-191.
56. Perry JR, Stolk L, Franceschini N, Lunetta KL, Zhai G, McArdle PF, Smith AV, Aspelund T, Bandinelli S, Boerwinkle E, Cherkas L, Eiriksdottir G, Estrada K, Ferrucci L, Folsom AR, Garcia M, Gudnason V, Hofman A, Karasik D, Kiel DP, Launer LJ, van Meurs J, Nalls MA, Rivadeneira F, Shuldiner AR, Singleton A, Soranzo N, Tanaka T, Visser JA, Weedon MN, Wilson SG, Zhuang V, Streeten EA, Harris TB, Murray A, Spector TD, Demerath EW, Uitterlinden AG, Murabito JM. Meta-analysis of genome-wide association data identifies two loci influencing age at menarche. Nat Genet 2009;41(6):648-650.
57. Ong KK, Elks CE, Li S, Zhao JH, Luan J, Andersen LB, Bingham SA, Brage S, Smith GD, Ekelund U, Gillson CJ, Glaser B, Golding J, Hardy R, Khaw K, Kuh D, Luben R, Marcus M, McGeehin MA, Ness AR, Northstone K, Ring SM, Rubin C, Sims MA, Song K, Strachan DP, Vollenweider P, Waeber G, Waterworth DM, Wong A, Deloukas P, Barroso I, Mooser V, Loos RJ, Wareham NJ. Genetic variation in LIN28B is associated with the timing of puberty. Nat Genet 2009;41(6):729-733.
58. Widen E, Ripatti S, Cousminer DL, Surakka I, Lappalainen T, Jarvelin M, Eriksson JG, Raitakari O, Salomaa V, Sovio U, Hartikainen A, Pouta A, McCarthy MI, Osmond C, Kajantie E, Lehtimaki T, Viikari J, Kahonen M, Tyler-Smith C, Freimer N, Hirschhorn JN, Peltonen L, Palotie A. Distinct variants at LIN28B influence growth in height from birth to adulthood. Am J Hum Genet 2010;86(5):773-782.
59. Ong KK, Elks CE, Wills AK, Wong A, Wareham NJ, Loos RJ, Kuh D, Hardy R. Associations between the pubertal timing-related variant in LIN28B and BMI vary across the life course. J Clin Endocrinol Metab 2011;96(1):125-129.
60. Rougvie AE. Intrinsic and extrinsic regulators of developmental timing: from miRNAs to nutritional cues. Development 2005;132(17):3787-3798.
61. Viswanathan SR, Daley GQ. Lin28: A microRNA regulator with a macro role. Cell 2010;140(4):445-449.
62. Altarejos JY, Goebel N, Conkright MD, Inoue H, Xie J, Arias CM, Sawchenko PE, Montminy M. The Creb1 coactivator Crtc1 is required for energy balance and fertility. Nat Med 2008;14(10):1112-1117.
63. Roa J, Tena-Sempere M. Energy balance and puberty onset: emerging role of central mTOR signaling. Trends Endocrinol Metab 2010;21(9):519-528.
64. Ibanez L, Ong K, Valls C, Marcos MV, Dunger DB, de Zegher F. Metformin treatment to prevent early puberty in girls with precocious pubarche. J Clin Endocrinol Metab 2006;91(8):2888-2891.
65. Kapahi P, Chen D, Rogers AN, Katewa SD, Li PW, Thomas EL, Kockel L. With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging. Cell Metab 2010;11(6):453-465.
66. Stanfel MN, Shamieh LS, Kaeberlein M, Kennedy BK. The TOR pathway comes of age. Biochim Biophys Acta 2009;1790(10):1067-1074.
67. Polak P, Hall MN. mTOR and the control of whole body metabolism. Curr Opin Cell Biol 2009;21(2):209-218.
68. Harrison DE, Strong R, Sharp ZD, Nelson JF, Astle CM, Flurkey K, Nadon NL, Wilkinson J, Frenkel K, Carter CS, Pahor M, Javors MA, Fernandez E, Miller RA. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature 2009;460(7253):392-395.
69. Miller RA, Harrison DE, Astle C, Baur JA, Boyd AR, de Cabo R, Fernandez E, Flurkey K, Javors MA, Nelson JF, Orihuela CJ, Pletcher S, Sharp ZD, Sinclair D, Starnes JW, Wilkinson J, Nadon NL, Strong R. Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice. J Gerontol A Biol Sci Med Sci 2011;66(2):191-201.
70. Anisimov VN, Zabezhinski MA, Popovich IG, Piskunova TS, Semenchenko AV, Tyndyk ML, Yurova MN, Antoch MP, Blagosklonny MV. Rapamycin extends maximal lifespan in cancer-prone mice. Am J Pathol. 2011;176:2092-7
71. Miranda N, Tovar AR, Palacios B, Torres N. [AMPK as a cellular energy sensor and its function in the organism]. Rev Invest Clin 2007;59(6):458-469.
72. Zong H, Ren JM, Young LH, Pypaert M, Mu J, Birnbaum MJ, Shulman GI. AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation. Proc Natl Acad Sci U S A 2002;99(25):15983-15987.
73. Reznick RM, Zong H, Li J, Morino K, Moore IK, Yu HJ, Liu Z, Dong J, Mustard KJ, Hawley SA, Befroy D, Pypaert M, Hardie D, Young LH, Shulman GI. Aging-associated reductions in AMP-activated protein kinase activity and mitochondrial biogenesis. Cell Metab 2007;5(2):151-156.
74. Anisimov V, Egormin P, Bershtein L, Zabezhinskii M, Piskunova T, Popovich I, Semenchenko A. Metformin decelerates aging and development of mammary tumors in HER-2/neu transgenic mice. Bull Exp Biol Med 2005;139(6):721-723.
75. Anisimov VN, Berstein LM, Egormin PA, Piskunova TS, Popovich IG, Zabezhinski MA, Tyndyk ML, Yurova MV, Kovalenko IG, Poroshina TE, Semenchenko AV. Metformin slows down aging and extends life span of female SHR mice. Cell Cycle 2008;7(17):2769-2773.
76. Anisimov VN, Berstein LM, Popovich IG, Zabezhinski MA, Egormin PA, Piskunova TS, Semenchenko AV, Tyndyk ML, Yurova MN, Kovalenko IG, Poroshina TE. If started early in life, metformin treatment increases life span and postpones tumors in female SHR mice. Aging 2011; 3(3): (this issue).
77. Luchsinger JA, Gustafson DR. Adiposity, type 2 diabetes and Alzheimer's disease. J Alzheimers Dis 2009;16(4):693-704.
78. Lakshman R, Forouhi NG, Sharp SJ, Luben R, Bingham SA, Khaw K, Wareham NJ, Ong KK. Early age at menarche associated with cardiovascular disease and mortality. J Clin Endocrinol Metab 2009;94(12):4953-4960.