Mitochondria-dependent apoptosis of activated T lymphocytes induced by astin C, a plant cyclopeptide, for preventing murine experimental colitis

Biochemical Pharmacology

Volumn 82, Issue 3, 2011, Pages 260-268

  Shen, Yan ^a   Luo, Qiong ^a   Xu, Huimin ^b   Gong, Fangyuan ^a   Zhou, Xiaobin ^a   Sun, Yang ^a   Wu, Xuefeng ^a   Liu, Wen ^a   Zeng, Guangzhi ^b   Tan, Ninghua ^b   Xu, Qiang ^a  

^a NANJING UNIVERSITY   (China)

^b KUNMING INSTITUTE OF BOTANY   (China)

Author keywords

Apoptosis; Astin C; Colitis; Mitochondria; T lymphocyte

Indexed keywords

ASTIN C; CASPASE 3; CASPASE 8; CASPASE 9; CYCLOPEPTIDE; CYTOCHROME C; INTERLEUKIN 17; INTERLEUKIN 4; PROTEIN BAD; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; ASTERACEAE; COLITIS; CONTROLLED STUDY; DRUG ISOLATION; ENTERITIS; FEMALE; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; UPREGULATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; APOPTOSIS; ASTER PLANT; CELLS, CULTURED; COLITIS; CYTOKINES; FEMALE; GENE EXPRESSION REGULATION; MICE; MICE, INBRED C57BL; MITOCHONDRIA; PEPTIDES, CYCLIC; PLANT ROOTS; T-LYMPHOCYTES; TRINITROBENZENESULFONIC ACID;

EID: 79959568087     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2011.04.013     Document Type: Article

References (32)

1. A. Strasser, and M. Pellegrini T-lymphocyte death during shutdown of an immune response Trends Immunol 25 2004 610 615 (Pubitemid 39369738)
2. D.K. Podolsky Inflammatory bowel disease (1) N Engl J Med 325 1991 928 937
3. C. Fiocchi Inflammatory bowel disease: etiology and pathogenesis Gastroenterology 115 1998 182 205 (Pubitemid 28307304)
4. M. Boirivant, M. Marini, G. Di Felice, A.M. Pronio, C. Montesani, and R. Tersigni Lamina propria T cells in Crohn's disease and other gastrointestinal inflammation show defective CD2 pathway-induced apoptosis Gastroenterology 116 1999 557 565 (Pubitemid 29106763)
5. K. Ina, J. Itoh, K. Fukushima, K. Kusugami, T. Yamaguchi, and K. Kyokane Resistance of Crohn's disease T cells to multiple apoptotic signals is associated with a Bcl-2/Bax mucosal imbalance J Immunol 163 1999 1081 1090 (Pubitemid 29328123)
6. M.F. Neurath, S. Finotto, I. Fuss, M. Boirivant, P.R. Galle, and W. Strober Regulation of T-cell apoptosis in inflammatory bowel disease: to die or not to die, that is the mucosal question Trends Immunol 22 2001 21 26 (Pubitemid 32675276)
7. R. Atreya, and M.F. Neurath New therapeutic strategies for treatment of inflammatory bowel disease Mucosal Immunol 1 2008 175 182 (Pubitemid 351541303)
8. R. Atreya, J. Mudter, S. Finotto, J. Mullberg, T. Jostock, and S. Wirtz Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in crohn disease and experimental colitis in vivo Nat Med 6 2000 583 588 (Pubitemid 30305911)
9. A. Stallmach, T. Marth, B. Weiss, B.M. Wittig, A. Hombach, and C. Schmidt An interleukin 12 p40-IgG2b fusion protein abrogates T cell mediated inflammation: anti-inflammatory activity in Crohn's disease and experimental colitis in vivo Gut 53 2004 339 345 (Pubitemid 38241326)
10. S.J. van Deventer Transmembrane TNF-alpha, induction of apoptosis, and the efficacy of TNF-targeting therapies in Crohn's disease Gastroenterology 121 2001 1242 1246 (Pubitemid 33022107)
11. J. Doering, B. Begue, M.J. Lentze, F. Rieux-Laucat, O. Goulet, and J. Schmitz Induction of T lymphocyte apoptosis by sulphasalazine in patients with Crohn's disease Gut 53 2004 1632 1638 (Pubitemid 39434107)
12. + T lymphocytes J Clin Invest 111 2003 1133 1145 (Pubitemid 36519931)
13. N.H. Tan, and J. Zhou Plant cyclopeptides Chem Rev 106 2006 840 895
14. H. Morita, S. Nagashima, K. Takeya, and H. Itokawa Astins A and B, antitumor cyclic pentapeptides from Aster tataricus Chem Pharm Bull (Tokyo) 41 1993 992 993 (Pubitemid 23240074)
15. F. Rossi, G. Zanotti, M. Saviano, R. Iacovino, P. Palladino, and G. Saviano New antitumour cyclic astin analogues: synthesis, conformation and bioactivity J Pept Sci 10 2004 92 102 (Pubitemid 38248020)
16. R. Cozzolino, P. Palladino, F. Rossi, G. Cali, E. Benedetti, and P. Laccetti Antineoplastic cyclic astin analogues kill tumour cells via caspase-mediated induction of apoptosis Carcinogenesis 26 2005 733 739 (Pubitemid 41214335)
17. I. Vermes, C. Haanen, H. Steffens-Nakken, and C. Reutelingsperger A novel assay for apoptosis flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V J Immunol Methods 184 1995 39 51
18. Y. Sun, X.X. Wu, Y. Yin, F.Y. Gong, Y. Shen, and T.T. Cai Novel immunomodulatory properties of cirsilineol through selective inhibition of IFN-gamma signaling in a murine model of inflammatory bowel disease Biochem Pharmacol 79 2010 229 238
19. N.E. Ruyssers, B.Y. De Winter, J.G. De Man, A. Loukas, M.S. Pearson, and J.V. Weinstock Therapeutic potential of helminth soluble proteins in TNBS-induced colitis in mice Inflamm Bowel Dis 15 2009 491 500
20. J. Busserolles, M. Paya, M.V. D'Auria, L. Gomez-Paloma, and M.J. Alcaraz Protection against 2,4,6-trinitrobenzenesulphonic acid-induced colonic inflammation in mice by the marine products bolinaquinone and petrosaspongiolide M Biochem Pharmacol 69 2005 1433 1440 (Pubitemid 40602443)
21. D. Chen, K.G. Daniel, M.S. Chen, D.J. Kuhn, K.R. Landis-Piwowar, and Q.P. Dou Dietary flavonoids as proteasome inhibitors and apoptosis inducers in human leukemia cells Biochem Pharmacol 69 2005 1421 1432 (Pubitemid 40602442)
22. S.Y. Chien, Y.C. Wu, J.G. Chung, J.S. Yang, H.F. Lu, and M.F. Tsou Quercetin-induced apoptosis acts through mitochondrial- and caspase-3-dependent pathways in human breast cancer MDA-MB-231 cells Hum Exp Toxicol 28 2009 493 503
23. T. Nakagawa, H. Zhu, N. Morishima, E. Li, J. Xu, and B.A. Yankner Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta Nature 403 2000 98 103 (Pubitemid 30038529)
24. S.M. Kim, H.S. Park, D.Y. Jun, H.J. Woo, M.H. Woo, and C.H. Yang Mollugin induces apoptosis in human Jurkat T cells through endoplasmic reticulum stress-mediated activation of JNK and caspase-12 and subsequent activation of mitochondria-dependent caspase cascade regulated by Bcl-xL Toxicol Appl Pharmacol 241 2009 210 220
25. L. Peyrin-Biroulet Anti-TNF therapy in inflammatory bowel diseases: a huge review Minerva Gastroenterol Dietol 56 2010 233 243
26. R. Calne Cyclosporine as a milestone in immunosuppression Transplant Proc 36 2004 13S 15S (Pubitemid 38373825)
27. J.T. Opferman, and S.J. Korsmeyer Apoptosis in the development and maintenance of the immune system Nat Immunol 4 2003 410 415 (Pubitemid 36592430)
28. R. Watanabe-Fukunaga, C.I. Brannan, N.G. Copeland, N.A. Jenkins, and S. Nagata Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis Nature 356 1992 314 317
29. X.M. Xu, J.P. Yu, X.F. He, J.H. Li, L.L. Yu, and H.G. Yu Effects of garlicin on apoptosis in rat model of colitis World J Gastroenterol 11 2005 4579 4582
30. H. Morita, S. Nagashima, Y. Uchiumi, O. Kuroki, K. Takeya, and H. Itokawa Cyclic peptides from higher plants XXVIII. Antitumor activity and hepatic microsomal biotransformation of cyclic pentapeptides, astins, from Aster tataricus Chem Pharm Bull (Tokyo) 44 1996 1026 1032 (Pubitemid 26194025)
31. H. Itokawa, K. Takeya, Y. Hitotsuyanagi, and H. Morita Antitumor compounds isolated from higher plant J Biochem Mol Biol Biophys 4 2000 213 222 (Pubitemid 30348651)
32. Y. Sun, Y. Qin, F.Y. Gong, X.F. Wu, Z.C. Hua, and T. Chen Selective triggering of apoptosis of concanavalin A-activated T cells by fraxinellone for the treatment of T-cell-dependent hepatitis in mice Biochem Pharmacol 77 2009 1717 1724