New bis(thiosemicarbazonate) gold(III) complexes inhibit HIV replication at cytostatic concentrations: Potential for incorporation into virostatic cocktails

Journal of Inorganic Biochemistry

Volumn 105, Issue 9, 2011, Pages 1173-1180

  Fonteh, Pascaline N ^a,b   Keter, Frankline K ^a   Meyer, Debra ^a  

^a UNIVERSITY OF PRETORIA   (South Africa)

^b MINTEK   (South Africa)

Author keywords

Anti HIV activity; Bis(thiosemicarbazonate) gold(III) complexes; Cytostasis; Immune effect

Indexed keywords

ANTIVIRUS AGENT; DIACETYL BIS (N4 ETHYLTHIOSEMICARBAZONATE) GOLD (III) CHLORIDE; DIACETYL BIS (N4 METHYLTHIOSEMICARBAZONATE) GOLD (III) CHLORIDE; GAMMA INTERFERON; GLYOXAL BIS (N4 ETHYLTHIOSEMICARBAZONATE) GOLD (III) CHLORIDE; GLYOXAL BIS (N4 METHYLIOSEMICARBAZONATE) GOLD (III) CHLORIDE; THIOSEMICARBAZONE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CD4+ T LYMPHOCYTE; CELL PROLIFERATION; COMPLEX FORMATION; COMPUTER MODEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOSTASIS; DRUG PURITY; DRUG SCREENING; DRUG SOLUBILITY; DRUG SYNTHESIS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; INFRARED SPECTROSCOPY; LIPOPHILICITY; MICROANALYSIS; PROTON NUCLEAR MAGNETIC RESONANCE; VIRUS INHIBITION;

ANTI-HIV AGENTS; ANTIGENS, CD4; CD4-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CELL SURVIVAL; COORDINATION COMPLEXES; CYTOSTATIC AGENTS; FEMALE; FLOW CYTOMETRY; FLUORESCEINS; GENES, REPORTER; GOLD; HELA CELLS; HIV INFECTIONS; HIV-1; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LUCIFERASES; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; SPECTROPHOTOMETRY, INFRARED; SUCCINIMIDES; THIOSEMICARBAZONES; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS;

EID: 79959535962     PISSN: 01620134     EISSN: 18733344     Source Type: Journal    
DOI: 10.1016/j.jinorgbio.2011.05.011     Document Type: Article

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